Search filters

List of works by Lisa R Yanek

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A Simple Scalable Association Hypothesis Test Combining Gene-wide Evidence From Multiple Polymorphisms

scientific article published on March 2014

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease

scientific article

A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry.

scientific article

A common variant in the Von Willebrand factor gene is associated with multiple functional consequences.

scientific article

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

scientific article published on 02 August 2019

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans

scientific article

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

scientific article

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

scientific article

A monocyte chemoattractant protein-1 gene polymorphism is associated with occult ischemia in a high-risk asymptomatic population

scientific article published on 24 August 2006

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability

scientific article published on 29 May 2008

Age differences in periventricular and deep white matter lesions.

scientific article

Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts

scientific article published on 26 December 2019

Assessment of Global Coronary Heart Disease Risk in Overweight and Obese African‐American Women ⬇️

scientific article published on May 1, 2003

Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease

scientific article

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Body image assessment: comparison of figure rating scales among urban Black women.

scientific article published on January 2002

Body image preferences among urban African Americans and whites from low income communities

scientific article published on January 1999

Casual chocolate consumption and inhibition of platelet function.

scientific article

Cerebral small vessel disease genomics and its implications across the lifespan

scientific article published on 08 December 2020

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

scientific article

Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities

scientific article published on 10 June 2020

Common genetic variants influence human subcortical brain structures

scientific article

Comparison of coronary calcium and stress myocardial perfusion imaging in apparently healthy siblings of individuals with premature coronary artery disease.

scientific article

Comparison of food frequency and dietary recall methods in African-American women

scientific article published in November 2001

Comparison of the effectiveness of a telephone 24-hour dietary recall method vs an in-person method among urban African-American women

scientific article published on October 2000

Correction: Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry.

scientific article published on 21 November 2011

Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

scientific article

Detecting occult coronary disease in a high-risk asymptomatic population

scientific article published on 01 February 2003

Diabetes and Platelet Response to Low-Dose Aspirin

scientific article published on 01 December 2018

Dietary Counseling for High Blood Cholesterol in Families at Risk of Coronary Disease

scientific article published on 01 January 2001

Dietary fat patterns in urban African American women

scientific article

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

scientific article

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

scientific article published on 24 August 2020

Effect of obesity on platelet reactivity and response to low-dose aspirin.

scientific article published in January 2010

Effect of positive well-being on incidence of symptomatic coronary artery disease

scientific article published on 28 June 2013

Effect of white matter lesions on manual dexterity in healthy middle-aged persons

scientific article published on 10 April 2015

Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies

scientific article published on 10 January 2019

Endomyocardial Biopsy Characterization of Heart Failure With Preserved Ejection Fraction and Prevalence of Cardiac Amyloidosis

scientific article published on 05 July 2020

Ethnic-specific determinants of exercise capacity in a healthy high-risk population

scientific article published in June 2012

Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World

Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World

scientific article published in 2019

Exome Chip Analysis Identifies Low-Frequency a on Brain Magnetic Imaging

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation

scientific article

Extreme deep white matter hyperintensity volumes are associated with African American race

scientific article

Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations

scientific article

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium

scientific article published on 2 February 2012

Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

scientific article published on 13 November 2020

Genetics of coronary artery calcification among African Americans, a meta-analysis

scientific article

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

scientific article published on 19 December 2016

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations

scientific article

Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network

scientific article published on 26 February 2013

Genome-wide association of body fat distribution in African ancestry populations suggests new loci

scientific article

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

scientific article

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

scientific article

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

scientific article published in Nature Communications

Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study / Study of Latinos (HCHS/SOL).

scientific article published on 17 May 2017

Genome-wide association study of platelet aggregation in African Americans

scientific article published on 30 May 2015

Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).

scientific article

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

scientific article

Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists

scientific article

Genome-wide meta-analyses of smoking behaviors in African Americans

scientific article

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

scientific article published on 13 October 2017

Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program

scientific article published on 06 May 2020

Glucose levels in the normal range predict incident diabetes in families with premature coronary heart disease

scientific article published on 23 May 2006

Greater collagen-induced platelet aggregation following cyclooxygenase 1 inhibition predicts incident acute coronary syndromes

scientific article

Heritability of platelet function in families with premature coronary artery disease

scientific article

Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1

scientific article (publication date: 15 May 2007)

Hypertension Among Siblings of Persons With Premature Coronary Heart Disease ⬇️

scientific article published on July 1, 1998

Hypertension Is Associated with White Matter Disruption in Apparently Healthy Middle-Aged Individuals

scientific article published on 15 November 2018

Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression

scientific article

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry

scientific article

Impact of Self-Preference Community Fitness Interventions in High-Risk African Americans

scientific article

Impact of a community-based multiple risk factor intervention on cardiovascular risk in black families with a history of premature coronary disease

scientific article published in March 2005

Incidence of coronary artery disease in siblings of patients with premature coronary artery disease: 10 years of follow-up.

scientific article

Independent metabolic syndrome variants predict new-onset coronary artery disease.

scientific article

Integrity of Induced Pluripotent Stem Cell (iPSC) Derived Megakaryocytes as Assessed by Genetic and Transcriptomic Analysis

scientific article

Interaction of body mass index and framingham risk score in predicting incident coronary disease in families

scientific article published on 01 April 2005

KLOTHO allele status and the risk of early-onset occult coronary artery disease

scientific article

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

scientific article

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

scientific article

Lean Mass and Fat Mass as Contributors to Physical Fitness in an Overweight and Obese African American Population

scientific article published on January 2015

Leukocyte count is associated with increased platelet reactivity and diminished response to aspirin in healthy individuals with a family history of coronary artery disease

scientific article published on 30 January 2009

Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data

scientific article published on 22 January 2019

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

Many sequence variants affecting diversity of adult human height

scientific article published in May 2008

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

scientific article published on 10 May 2019

Meta-analysis of correlated traits via summary statistics from GWASs with an application in hypertension

scientific article

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes

scientific article

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

scientific article published on 12 November 2019

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

scientific article published in Nature Communications

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

scientific article published on 21 November 2016

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)

Native platelet aggregation and response to aspirin in persons with the metabolic syndrome and its components

scientific article

Noncalcified coronary plaque volumes in healthy people with a family history of early onset coronary artery disease.

scientific article published on 27 February 2014

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

Partial derivatives meta-analysis: pooled analyses when individual participant data cannot be shared

Physical activity patterns of urban African Americans

scientific article published on April 1, 1998

Platelet hyperreactivity in women from families with premature atherosclerosis

scientific article (publication date: 2003)

Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular disease.

scientific article

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

scientific article

Pleiotropic genes for metabolic syndrome and inflammation

scientific article

Predictors of low-density lipoprotein particle size in a high-risk African-American population

scientific article

Prevalence of hypercholesterolemia among siblings of persons with premature coronary heart disease. Application of the Second Adult Treatment Panel guidelines

scientific article published in August 1996

Project Joy: faith based cardiovascular health promotion for African American women

scientific article published in January 2001

Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study

scientific article

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

scientific article

Recombination rates in admixed individuals identified by ancestry-based inference

scientific article published on 20 July 2011

Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population

scientific article (publication date: 15 September 2006)

Relation of Plasma Lipoprotein(a) to Subclinical Coronary Plaque Volumes, Three-Vessel and Left Main Coronary Disease, and Severe Coronary Stenoses in Apparently Healthy African-Americans With a Family History of Early-Onset Coronary Artery Disease.

scientific article

Relation of subclinical coronary artery atherosclerosis to cerebral white matter disease in healthy subjects from families with early-onset coronary artery disease

scientific article published on 03 June 2013

SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a).

scientific article published on 20 September 2016

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption

scientific article

Severity of inducible myocardial ischemia predicts incident acute coronary syndromes in asymptomatic individuals with a family history of premature coronary artery disease.

scientific article published on 12 November 2011

Sex differences in platelet reactivity and response to low-dose aspirin therapy

scientific article (publication date: 22 March 2006)

Shaping anesthetic techniques to reduce post-operative delirium (SHARP) study: a protocol for a prospective pragmatic randomized controlled trial to evaluate spinal anesthesia with targeted sedation compared with general anesthesia in older adults u

scientific article published on 27 October 2019

Silent myocardial ischaemia and long-term coronary artery disease outcomes in apparently healthy people from families with early-onset ischaemic heart disease

scientific article published on 23 July 2011

Silent small-vessel cerebrovascular disease and silent myocardial ischemia in families with premature coronary disease

scientific article published on 28 April 2009

Single nucleotide polymorphisms in monocyte chemoattractant protein-1 and its receptor act synergistically to increase the risk of carotid atherosclerosis

scientific article

Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

scientific article

Sociodemographic, behavioral, and psychological correlates of current overweight and obesity in older, urban african american women

scientific article published on August 2004

Spiritual beliefs and barriers among managed care practitioners

scientific article published in January 2005

Sustainability of a multiple risk factor intervention on cardiovascular disease in high-risk African American families.

scientific article published in January 2008

Targeted deep resequencing identifies coding variants in the PEAR1 gene that play a role in platelet aggregation

scientific article

Targeted deep sequencing of the PEAR1 locus for platelet aggregation in European and African American families

scientific article published on 19 March 2018

The association of brachial artery diameter with noncalcified coronary plaque burden in apparently healthy individuals

scientific article published on December 2013

The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans

scientific article

The relationship of family history and risk of type 2 diabetes differs by ancestry

scientific article published on 21 May 2018

The robustness of generalized estimating equations for association tests in extended family data

scientific article

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

scientific article

Trans-ethnic meta-analysis of white blood cell phenotypes

scientific article

Transcriptional profile of platelets and iPSC-derived megakaryocytes from whole genome and RNA sequencing

scientific article published on 22 October 2020

Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis

scientific article published in December 2023

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article published on 23 December 2019

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article

Using Mobile Health Tools to Assess Physical Activity Guideline Adherence and Smoking Urges: Secondary Analysis of mActive-Smoke

scientific article published on 06 January 2020

White Matter Injury Is Associated with Reduced Manual Dexterity and Elevated Serum Ceramides in Subjects with Cerebral Small Vessel Disease

scientific article published on 04 December 2020

White Matter Lesion Progression and Cognitive Function Over 5 Years in a Young Susceptible Population

scientific article published on 30 August 2017

Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation

scientific article published on 16 March 2017

Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium

scientific article published on 05 January 2021

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

scientific article

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

article

Women with a low Framingham risk score and a family history of premature coronary heart disease have a high prevalence of subclinical coronary atherosclerosis

scientific article (publication date: December 2005)

Paulina is supported by:

About Paulina

Help