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List of works by Susan K Pierce

A Simple, Versatile Antibody-Based Barcoding Method for Flow Cytometry.

scientific article published on 20 July 2016

A Streamlined Approach to Antibody Novel Germline Allele Prediction and Validation

scientific article published on 4 September 2017

A conformation-induced oligomerization model for B cell receptor microclustering and signaling

scientific article

A malaria vaccine protects Aotus monkeys against virulent Plasmodium falciparum infection

scientific article published on 22 May 2017

A method for analyzing protein-protein interactions in the plasma membrane of live B cells by fluorescence resonance energy transfer imaging as acquired by total internal reflection fluorescence microscopy

scientific article

A peptide binding protein having a role in antigen presentation is a member of the HSP70 heat shock family

scientific article

A peptide binding protein which plays a role in antigen presentation

scientific article

A positive correlation between atypical memory B cells and Plasmodium falciparum transmission intensity in cross-sectional studies in Peru and Mali

scientific article

A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray

scientific article

A role for MHC class II antigen processing in B cell development

scientific article

A role for lipid rafts in B cell antigen receptor signaling and antigen targeting

scientific journal article

A single-nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor alters the development of host immunity

scientific article published on 05 February 2020

Accurate immune repertoire sequencing reveals malaria infection driven antibody lineage diversification in young children

scientific article published on 14 September 2017

Adaptive NK cells in people exposed to Plasmodium falciparum correlate with protection from malaria

scientific article published on 12 April 2019

Advances and challenges in malaria vaccine development ⬇️

scientific article published on December 1, 2010

An Optimized Protocol to Analyze Glycolysis and Mitochondrial Respiration in Lymphocytes

scientific article published on 21 November 2016

Anti-immunoglobulin augments the B-cell antigen-presentation function independently of internalization of receptor-antigen complex

scientific article published on September 1985

Antibody-specific immunoregulation is restricted by the major histocompatibility gene complex ⬇️

scientific article published on 01 November 1982

Antigen affinity discrimination is an intrinsic function of the B cell receptor.

scientific article

Antigen processing: an interim report

scientific article

Antigen-induced oligomerization of the B cell receptor is an early target of Fc gamma RIIB inhibition.

scientific article

Antigen-presenting function of B lymphocytes

scientific article published on December 1988

Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors ⬇️

scientific article published on July 1, 2011

Atypical memory B cells are greatly expanded in individuals living in a malaria-endemic area

scientific article published on 10 July 2009

Atypical memory B cells in human chronic infectious diseases: An interim report

scientific article

Autoantigens act as tissue-specific chemoattractants.

scientific article

B Cells Produce Type 1 IFNs in Response to the TLR9 Agonist CpG-A Conjugated to Cationic Lipids.

scientific article published on 26 June 2017

B cell analysis of ethnic groups in Mali with differential susceptibility to malaria

scientific article

B cell antigen receptor signaling links biochemical changes in the class II peptide-loading compartment to enhanced processing

scientific article published on 01 December 1996

B cell memory: building two walls of protection against pathogens

scientific article published on 13 December 2019

B cell signaling in context

scientific article published on 08 July 2019

B cell signaling is regulated by induced palmitoylation of CD81.

scientific article published on 25 May 2004

Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion

scientific article

CD21/CD19 coreceptor signaling promotes B cell survival during primary immune responses

scientific article published on 01 September 2005

CD8+ T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature

scientific article

CD8+ T cells target cerebrovasculature in children with cerebral malaria

scientific article published on 01 March 2020

Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk.

scientific article

Cellular and subcellular distribution of PBP72/74, a peptide-binding protein that plays a role in antigen processing

scientific article published on January 1991

Change we can believe in--of the conformational type. Workshop on the Initiation of Antigen Receptor Signaling

scientific article published on 13 March 2009

Characteristics of peptides which compete for presented antigen-binding sites on antigen-presenting cells

scientific article published in May 1990

Chronic Exposure to Plasmodium falciparum Is Associated with Phenotypic Evidence of B and T Cell Exhaustion ⬇️

scientific article published on December 21, 2012

Cloning of the Gene Encoding Peptide-Binding Protein 74 Shows that it is a New Member of the Heat Shock Protein 70 Family ⬇️

scientific article published on June 1, 1993

Cross-linking cell surface class II molecules stimulates Ig-mediated B cell antigen processing

scientific article published on 01 August 1995

Cutting edge: B cell antigen receptor signaling occurs outside lipid rafts in immature B cells

scientific article

Desperately Seeking Therapies for Cerebral Malaria

scientific article published on 01 January 2020

Discrimination of membrane antigen affinity by B cells requires dominance of kinetic proofreading over serial engagement

scientific article published on 12 September 2011

Do we know enough to find an adjunctive therapy for cerebral malaria in African children? ⬇️

scientific article published on 22 November 2017

Encoding immunological memory in the initiation of B-cell receptor signaling

scientific article

Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments

scientific article published on 02 October 2011

Entry of B cell antigen receptor and antigen into class II peptide-loading compartment is independent of receptor cross-linking ⬇️

scientific article published on 01 November 1995

Epstein-Barr virus coopts lipid rafts to block the signaling and antigen transport functions of the BCR.

scientific article published in January 2001

Ethnic differences in susceptibility to malaria: what have we learned from immuno-epidemiological studies in West Africa?

scientific article published on 27 March 2015

Exhaustion may not be in the human B cell vocabulary, at least not in malaria

scientific article published on 25 September 2019

Expression of inhibitory receptors by B cells in chronic human infectious diseases restricts responses to membrane-associated antigens

scientific article published on 24 July 2020

FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling ⬇️

scientific article published on September 8, 2011

Floating the raft hypothesis for immune receptors: access to rafts controls receptor signaling and trafficking

scientific article

Floating the raft hypothesis: lipid rafts play a role in immune cell activation

scientific article

Floating the raft hypothesis: the roles of lipid rafts in B cell antigen receptor function

scientific article

Fluorescence resonance energy transfer in living cells reveals dynamic membrane changes in the initiation of B cell signaling

scholarly article

Formation of BCR oligomers provides a mechanism for B cell affinity discrimination ⬇️

scientific article published on May 19, 2012

From zero to sixty and back to zero again: the metabolic life of B cells

scientific article published on 09 October 2018

Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice ⬇️

scientific article published on December 27, 2010

HLA-DM is present in one-fifth the amount of HLA-DR in the class II peptide-loading compartment where it associates with leupeptin-induced peptide (LIP)-HLA-DR complexes

scientific article published on 01 December 1996

High efficiency human memory B cell assay and its application to studying Plasmodium falciparum-specific memory B cells in natural infections

scientific article published on 22 September 2011

How location governs toll-like receptor signaling

scientific article published on June 2009

Identification of a peptide binding protein that plays a role in antigen presentation

scientific article

IgG3 regulates tissue-like memory B cells in HIV-infected individuals

article

In vitro growth-inhibitory activity and malaria risk in a cohort study in mali

scientific article

Increased Mitochondrial Biogenesis and Reactive Oxygen Species Production Accompany Prolonged CD4 T Cell Activation

scientific article published on 29 October 2018

Inhibiting the Mammalian target of rapamycin blocks the development of experimental cerebral malaria

scientific article published on 2 June 2015

Interleukin-1β-induced IRAK1 ubiquitination is required for TH-GM-CSF cell differentiation in T cell-mediated inflammation

scientific article published on 10 May 2019

Intracellular transport of invariant chain-MHC class II complexes to the peptide-loading compartment

scientific article

Intrinsic Differences in the Initiation of B Cell Receptor Signaling Favor Responses of Human IgG+ Memory B Cells over IgM+ Naive B Cells ⬇️

scientific article published on February 29, 2012

Intrinsic properties of human germinal center B cells set antigen affinity thresholds

scientific article published on 01 November 2018

Intrinsic properties of immunoglobulin IgG1 isotype-switched B cell receptors promote microclustering and the initiation of signaling

scientific article

Isolation of lipid rafts from B lymphocytes

scientific article

It's all about change: the antigen-driven initiation of B-cell receptor signaling

scientific article

Lipid rafts unite signaling cascades with clathrin to regulate BCR internalization

scientific article published on October 2002

Live cell imaging reveals that the inhibitory FcgammaRIIB destabilizes B cell receptor membrane-lipid interactions and blocks immune synapse formation

scientific article published on January 2008

Location is everything: lipid rafts and immune cell signaling.

scientific article

Longitudinal analysis of naturally acquired PfEMP1 CIDR domain variant antibodies identifies associations with malaria protection

scientific article published on 19 May 2020

MHC class II antigen processing in B cells: accelerated intracellular targeting of antigens

scientific article published on 01 June 1999

MRI demonstrates glutamine antagonist-mediated reversal of cerebral malaria pathology in mice.

scientific article published on 4 December 2018

Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease

scientific article

Malaria infection alters the expression of B-cell activating factor resulting in diminished memory antibody responses and survival

scientific article

Malaria parasite detection and cell counting for human and mouse using thin blood smear microscopy

scientific article published on 01 October 2018

Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function

scientific article published on 8 May 2015

Malaria-induced interferon-γ drives the expansion of Tbethi atypical memory B cells

scientific article published on 27 September 2017

Membrane heterogeneities in the formation of B cell receptor-Lyn kinase microclusters and the immune synapse

scientific article published on 21 July 2008

NK cells inhibit Plasmodium falciparum growth in red blood cells via antibody-dependent cellular cytotoxicity.

scientific article

No receptor stands alone: IgG B-cell receptor intrinsic and extrinsic mechanisms contribute to antibody memory

scientific article

PBP74, a new member of the mammalian 70-kDa heat shock protein family, is a mitochondrial protein

scientific article

PD-L2 Elbows out PD-L1 to Rescue T Cell Immunity to Malaria

scientific article published on August 2016

Peptides of 23 residues or greater are required to stimulate a high affinity class II-restricted T cell response

scientific article published on May 1993

Peptides related to the antigenic determinant block T cell recognition of the native protein as processed by antigen-presenting cells

scientific article published on 01 July 1986

Perspective on malaria eradication: is eradication possible without modifying the mosquito?

scientific article

Plasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasis

scientific article

Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P

scientific article (publication date: 3 April 2012)

Rafts and synapses in the spatial organization of immune cell signaling receptors ⬇️

scientific article published on November 1, 2001

Regulation of B cell receptor-mediated MHC class II antigen processing by FcgammaRIIB1

scientific article published on 01 March 1999

Reprogramming macrophage orientation by microRNA 146b targeting transcription factor IRF5

scientific article published on 29 October 2016

Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice

scientific article

Role of L3T4 and Ia in the heteroclitic response of T cells to cytochrome c.

scientific article

Second signals rescue B cells from activation-induced mitochondrial dysfunction and death

scientific article published on 09 July 2018

Separation of subcellular compartments containing distinct functional forms of MHC class II

scientific article

Sickle cell trait is associated with a delayed onset of malaria: implications for time-to-event analysis in clinical studies of malaria

scientific article published on November 2008

Structural and Functional Studies of Igαβ and Its Assembly with the B Cell Antigen Receptor

scientific article

Synergistic effects of antigen and soluble T-cell factors in B-lymphocyte activation ⬇️

scientific article published on September 1, 1984

T cell activation by processed antigen is equally blocked by I-E and I-A-restricted immunodominant peptides

scientific article published on 01 November 1987

T cell-dependent antigen adjuvanted with DOTAP-CpG-B but not DOTAP-CpG-A induces robust germinal center responses and high affinity antibodies in mice

scientific article

TLRs innate immunereceptors and Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) CIDR1α-driven human polyclonal B-cell activation

scientific article

Targeting glutamine metabolism rescues mice from late-stage cerebral malaria

scientific article

Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria.

scientific article

Testing in mice the hypothesis that melanin is protective in malaria infections

scientific article

Testing the impact of a single nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor on experimental cerebral malaria in mice

scientific article published on 12 August 2020

The B cell inhibitory Fc receptor triggers apoptosis by a novel c-Abl family kinase-dependent pathway

scientific article published on 22 August 2005

The CD19/CD21 complex functions to prolong B cell antigen receptor signaling from lipid rafts

scientific article published on February 2001

The Differentiation of Human Tonsil B Cells With the Phenotypic and Functional Characteristics of T-bet+ Atypical Memory B Cells in Malaria

scholarly article by Abhijit A Ambegaonkar et al published 2019 in Frontiers in Immunology

The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections

scientific article

The Regulation of Inherently Autoreactive VH4-34-Expressing B Cells in Individuals Living in a Malaria-Endemic Area of West Africa.

scientific article

The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum-specific memory B cells in semi-immune adults in Mali

scientific article published on 25 August 2009

The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparum-specific memory B cells in malaria-naive individuals

scientific article

The V gene repertoires of classical and atypical memory B cells in malaria-susceptible West African children

scientific article

The agonists of TLR4 and 9 are sufficient to activate memory B cells to differentiate into plasma cells in vitro but not in vivo

scientific article published on August 2008

The assembly and stability of MHC class II-(alpha beta)2 superdimers ⬇️

scientific article published on 01 September 1998

The autoinhibitory C-terminal SH2 domain of phospholipase C-γ2 stabilizes B cell receptor signalosome assembly

scientific article

The constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens.

scientific article

The effects of the Epstein-Barr virus latent membrane protein 2A on B cell function

scientific article

The impact of genetic susceptibility to systemic lupus erythematosus on placental malaria in mice

scientific article

The induction of B cells refractory to antibody-specific immunoregulation

scientific article published on 01 May 1982

The initiation of antigen-induced B cell antigen receptor signaling viewed in living cells by fluorescence resonance energy transfer

scientific article

The intracellular assembly of antigenic-peptide-class II complexes

scientific article published on January 1, 1995

The intracellular transport of MHC class II molecules in the absence of HLA-DM.

scientific article

The molecular assembly and organization of signaling active B-cell receptor oligomers.

scientific article

The nanoscale spatial organization of B-cell receptors on immunoglobulin M- and G-expressing human B-cells

scientific article published on 14 December 2016

The novelty of antigen-processing compartments ⬇️

scientific article published on August 15, 1995

The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis

scientific article

The role of surface immunoglobulin in the processing and presentation of antigen

scientific article published in January 1987

The role of the CD19/CD21 complex in B cell processing and presentation of complement-tagged antigens

scientific article published in July 2001

The scaffolding protein synapse-associated protein 97 is required for enhanced signaling through isotype-switched IgG memory B cell receptors

scientific article

The tetraspanin CD81 is necessary for partitioning of coligated CD19/CD21-B cell antigen receptor complexes into signaling-active lipid rafts

scientific article published on January 2004

The tipping points in the initiation of B cell signalling: how small changes make big differences.

scientific article

Time dependence of B cell processing and presentation of peptide and native protein antigens

Toll-like receptor 9 antagonizes antibody affinity maturation

scientific article

Translocation of the B cell antigen receptor into lipid rafts reveals a novel step in signaling

scientific journal article

Understanding the Initiation of B Cell Signaling Through Live Cell Imaging ⬇️

scientific article published on January 1, 2012

Ups and downs in the search for a Herpes simplex virus vaccine

scientific article

Viewing the antigen-induced initiation of B-cell activation in living cells

scientific article

Virus infection blocks the processing and presentation of exogenous antigen with the major histocompatibility complex class II molecules

scientific article published on August 1, 1992

Women in immunology: 2020 and beyond

scientific article published on 24 February 2020

World Malaria Day 2009: what malaria knows about the immune system that immunologists still do not.

scientific article published on May 2009

Wortmannin, a phosphatidylinositol 3-kinase inhibitor, blocks the assembly of peptide-MHC class II complexes ⬇️

scientific article published on 01 November 1997

Young lives lost as B cells falter: what we are learning about antibody responses in malaria

scientific article

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