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List of works by Christopher D Buckley

'I just thought it was normal aches and pains': a qualitative study of decision-making processes in patients with early rheumatoid arthritis

scientific article published on 18 August 2008

11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis

scientific article published in August 2018

11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy

scientific article published on 16 August 2019

11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation ⬇️

scientific article published on 31 August 2016

A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells.

scientific article

A HaemAtlas: characterizing gene expression in differentiated human blood cells

scientific article

A chemokine-dependent stromal induction mechanism for aberrant lymphocyte accumulation and compromised lymphatic return in rheumatoid arthritis

scientific article published on February 2005

A differential role for CD248 (Endosialin) in PDGF-mediated skeletal muscle angiogenesis ⬇️

scientific article (publication date: 2014)

A distinct profile of six soluble adhesion molecules (ICAM-1, ICAM-3, VCAM-1, E-selectin, L-selectin and P-selectin) in rheumatoid arthritis

scholarly article by A J Littler et al published February 1997 in British Journal of Rheumatology

A distinct subset of podoplanin (gp38) expressing F4/80+ macrophages mediate phagocytosis and are induced following zymosan peritonitis

scientific article published on 2 August 2010

A novel mechanism of neutrophil recruitment in a coculture model of the rheumatoid synovium

scientific article published on November 2005

A novel role for PECAM-1 (CD31) in regulating haematopoietic progenitor cell compartmentalization between the peripheral blood and bone marrow ⬇️

scientific article

A panel of monoclonal antibodies recognizing GPI-anchored ADP-ribosyltransferase ART4, the carrier of the Dombrock blood group antigens.

scientific article published in July 2005

A qualitative exploration of physical, mental and ocular fatigue in patients with primary Sjögren's Syndrome.

scientific article

A stromal address code defined by fibroblasts

scientific article

Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation.

scientific article

An in vitro model for analysing neutrophil migration into and away from the sub-endothelial space: Roles of flow and CD31

scientific article published on 01 January 2006

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis.

scientific article published on 9 May 2018

Analysis of the effects of stromal cells on the migration of lymphocytes into and through inflamed tissue using 3-D culture models

scientific article published on 16 October 2013

Annexin-1 modulates T-cell activation and differentiation

scientific article

Anti-collagen type II antibodies in patients with very early synovitis

scientific article

Anti-modified citrullinated vimentin (MCV) antibodies in patients with very early synovitis

scientific article published on 20 October 2009

Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment

scientific article

Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial protocol

scientific article published on 15 July 2019

Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation

scientific article published on 01 April 2019

Association between bone mineral density and C-reactive protein in a large population-based sample.

scientific article published in August 2012

Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans

scientific article

Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis.

scientific article

Author Correction: Pathogenic stromal cells as therapeutic targets in joint inflammation

scientific article published on 01 January 2019

Beliefs about medicines in patients with rheumatoid arthritis and systemic lupus erythematosus: a comparison between patients of South Asian and White British origin.

scientific article published on 29 March 2008

Bimodal Expansion of the Lymphatic Vessels Is Regulated by the Sequential Expression of IL-7 and Lymphotoxin α1β2 in Newly Formed Tertiary Lymphoid Structures

scientific article published on 29 July 2016

CCL21 expression pattern of human secondary lymphoid organ stroma is conserved in inflammatory lesions with lymphoid neogenesis.

scientific article

CD151 regulates tumorigenesis by modulating the communication between tumor cells and endothelium.

scientific article

CD248 expression on mesenchymal stromal cells is required for post-natal and infection-dependent thymus remodelling and regeneration

scientific article published on 20 July 2012

CD248+ stromal cells are associated with progressive chronic kidney disease.

scientific article published on 13 April 2011

CD248/Endosialin is dynamically expressed on a subset of stromal cells during lymphoid tissue development, splenic remodeling and repair.

scientific article published on 3 July 2007

CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism

scientific article published on 15 June 2015

CD31 Regulates Direction and Rate of Neutrophil Migration over and under Endothelial Cells ⬇️

scientific article published on September 1, 2003

CD31 is required on CD4+ T cells to promote T cell survival during Salmonella infection

scientific article

CD31 signals confer immune privilege to the vascular endothelium

scientific article

CD56bright human NK cells differentiate into CD56dim cells: role of contact with peripheral fibroblasts

scientific article

CLEC-2 expression is maintained on activated platelets and on platelet microparticles.

scientific article

CLEC-2 is required for development and maintenance of lymph nodes.

scientific article published on 14 February 2014

Cardiovascular risk factors and outcomes in early rheumatoid arthritis: a population-based study

scientific article published on 24 March 2020

Careers in clinical academic medicine: new opportunities or old threats?

scientific article published on January 2007

Celebrating the past, concentrating on the future: the next decade for AR&T.

scientific article published on 15 October 2015

Characterization of four CD18 mutants in leucocyte adhesion deficient (LAD) patients with differential capacities to support expression and function of the CD11/CD18 integrins LFA-1, Mac-1 and p150,95

scientific article published on 01 November 2001

Chemokine receptors in the rheumatoid synovium: upregulation of CXCR5

scientific article

Chemokine- and adhesion-dependent survival of neutrophils after transmigration through cytokine-stimulated endothelium

scientific article published on 3 February 2006

Corrigendum: Synovial tissue research: a state-of-the-art review

scientific article

Critical role of Src-Syk-PLC{gamma}2 signaling in megakaryocyte migration and thrombopoiesis.

scientific article

Crosstalk between mesenchymal stem cells and endothelial cells leads to downregulation of cytokine-induced leukocyte recruitment

scientific article published in December 2013

Curbing inflammation

scientific article published on October 2013

Cytokine mRNA profiling identifies B cells as a major source of RANKL in rheumatoid arthritis

scientific article

Cytokines in rheumatoid arthritis - shaping the immunological landscape

scientific article

DKK1 expression by synovial fibroblasts in very early rheumatoid arthritis associates with lymphocyte adhesion in an in vitro flow co-culture system

scientific article

Decrease in articular hypoxia and synovial blood flow at early time points following infliximab and etanercept treatment in rheumatoid arthritis

scientific article published on 8 September 2016

Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging

scientific article published on 10 August 2009

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

scientific article published on 06 May 2019

Delay in presentation to primary care physicians is the main reason why patients with rheumatoid arthritis are seen late by rheumatologists

scientific article published on 19 June 2007

Delays between the onset of symptoms and first rheumatology consultation in patients with rheumatoid arthritis in the UK: an observational study

scientific article published on 04 March 2019

Delays in assessment of patients with rheumatoid arthritis: variations across Europe.

scientific article published on 7 August 2011

Detailed analysis of intrahepatic CD8 T cells in the normal and hepatitis C-infected liver reveals differences in specific populations of memory cells with distinct homing phenotypes

scientific article published in July 2006

Development and formative evaluation of patient research partner involvement in a multi-disciplinary European translational research project

scientific article published on 19 February 2020

Diagnostic outcomes associated with ankle synovitis in early inflammatory arthritis: a cohort study

scientific article published on July 2014

Differential association of cytoplasmic signalling molecules SHP-1, SHP-2, SHIP and phospholipase C-gamma1 with PECAM-1/CD31

scientific article (publication date: 30 April 1999)

Differential expression of CD148 on leukocyte subsets in inflammatory arthritis.

scientific article published on January 2013

Differential expression, function and response to inflammatory stimuli of 11beta-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation ⬇️

scientific article published on January 2006

Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis ⬇️

scientific article published on 14 May 2015

Differential regulation of nuclear and mitochondrial Bcl-2 in T cell apoptosis.

scientific article published on January 2008

Differential survival of leukocyte subsets mediated by synovial, bone marrow, and skin fibroblasts: site-specific versus activation-dependent survival of T cells and neutrophils

scientific article

Direct observations of the kinetics of migrating T cells suggest active retention by endothelial cells with continual bidirectional migration

scientific article published on 23 October 2008

Disruptive innovation in rheumatology: new networks of global public-private partnerships are needed to take advantage of scientific progress

scientific article published on 05 March 2020

Distinct fibroblast subsets drive inflammation and damage in arthritis

scientific article published on 29 May 2019

Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis

scientific article published on 29 June 2020

Distinct types of fibrocyte can differentiate from mononuclear cells in the presence and absence of serum

scientific article (publication date: 2010)

Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin

scientific article published on 22 May 2015

Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to Lipopolysaccharide

scientific article published on 27 May 2015

Duffy antigen receptor for chemokines and CXCL5 are essential for the recruitment of neutrophils in a multicellular model of rheumatoid arthritis synovium

scientific article

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

scientific article published on 2 March 2012

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update ⬇️

scientific article published on 6 March 2017

Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin

scientific article

Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sjögren's syndrome

scientific article published on 01 November 2001

Editorial: Neutrophils live on a two-way street

scientific article published on 01 May 2011

Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts

scientific article published in Scientific Reports

Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium

scientific article (publication date: 9 May 2005)

Endothelial cells, fibroblasts and vasculitis

scientific article

Epidemiology of joint disorders in Parkinson's disease and their impact on health status

scientific article published on 02 July 2009

Epidemiology, morbidity and mortality in Behçet's disease: a cohort study using The Health Improvement Network (THIN)

scientific article published on 10 February 2020

Epidermal Notch1 recruits RORγ(+) group 3 innate lymphoid cells to orchestrate normal skin repair

scientific article published on 21 April 2016

Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions.

scientific article published on 23 March 2017

Epitope mapping and functional properties of anti-intercellular adhesion molecule-3 (CD50) monoclonal antibodies

scientific article published on February 1995

Evaluating the effects of an exercise program (Staying UpRight) for older adults in long-term care on rates of falls: study protocol for a randomised controlled trial

scientific article published on 08 January 2020

Expression of FcRL4 defines a pro-inflammatory, RANKL-producing B cell subset in rheumatoid arthritis

scientific article

Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis

scientific article published on 9 April 2015

Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide

scientific article

Fibroblasts and Osteoblasts in Inflammation and Bone Damage

scientific article published on 01 January 2018

Fibroblasts as novel therapeutic targets in chronic inflammation

scientific article published on 29 October 2007

Fibroblasts as therapeutic targets in rheumatoid arthritis and cancer

scientific article published on 24 February 2012

Fibroblasts from different sites may promote or inhibit recruitment of flowing lymphocytes by endothelial cells.

scientific article published on January 2009

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis.

scientific article published on 23 February 2018

Gain-of-Function Mutation of Tristetraprolin Impairs Negative Feedback Control of Macrophages In Vitro yet Has Overwhelmingly Anti-Inflammatory Consequences In Vivo.

scientific article published on 6 March 2017

Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways

scientific article

Generation and characterization of novel stromal specific antibodies

scientific article

Genetic Deletion of the Stromal Cell Marker CD248 (Endosialin) Protects against the Development of Renal Fibrosis.

scientific article published on 4 December 2015

Genomic Responses of Mouse Synovial Fibroblasts During Tumor Necrosis Factor-Driven Arthritogenesis Greatly Mimic Those in Human Rheumatoid Arthritis

scientific article published on 13 April 2017

Global gene expression profiles in fibroblasts from synovial, skin and lymphoid tissue reveals distinct cytokine and chemokine expression patterns ⬇️

scientific article published on October 1, 2003

Haematological abnormalities in new-onset rheumatoid arthritis and risk of common infections: a population-based study

scientific article published on 09 September 2019

Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis

scientific article published on 30 July 2018

Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease

scientific article published on 20 April 2015

IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs

scientific article

IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cells

scientific article published in July 2012

Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis.

scientific article published on 2 July 2018

Identification of a phenotypically and functionally distinct population of long-lived neutrophils in a model of reverse endothelial migration

scientific article published on 05 December 2005

Identification of a transitional fibroblast function in very early rheumatoid arthritis

scientific article published on 28 August 2017

Identification of novel antiacetylated vimentin antibodies in patients with early inflammatory arthritis

scientific article published on 09 July 2015

Identification of synovium-specific homing peptides by in vivo phage display selection.

scientific article

Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans

scientific article

IgG1 Is Required for Optimal Protection after Immunization with the Purified Porin OmpD from Salmonella Typhimurium.

scientific article published on 10 November 2017

Immune interactions in hepatic fibrosis.

scientific article

Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology

scientific article published on 18 June 2019

Immunofibroblasts regulate LTα3 expression in tertiary lymphoid structures in a pathway dependent on ICOS/ICOSL interaction

scientific article published on 04 May 2022

Increased expression of inducible co-stimulator on CD4+ T-cells in the peripheral blood and synovial fluid of patients with failed hip arthroplasties

scientific article published on February 2016

Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice

scientific article

Induction and transcriptional regulation of the co-inhibitory gene module in T cells

scientific article published in Nature

Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets

scientific article

Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells ⬇️

scientific article published on July 2012

Inhibition of T cell apoptosis in the aqueous humor of patients with uveitis by IL-6/soluble IL-6 receptor trans-signaling.

scientific article published in October 2004

Inhibition of fibrocyte differentiation by serum amyloid P

scientific article

Interaction between integrin alpha9beta1 and vascular cell adhesion molecule-1 (VCAM-1) inhibits neutrophil apoptosis

scientific article published on 13 October 2005

Interleukin 23 is critical in the pathogenesis of spondyloarthropathy and acts on a novel population of interleukin 23R+ entheseal resident cells

scientific article published in The Lancet

Introducing our 20th anniversary collection

scientific article published on 20 November 2019

Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers

scientific article

Leukocyte trafficking between stromal compartments: lessons from rheumatoid arthritis

scientific article published on 01 August 2018

Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver

scientific article published on 15 October 2008

Local and systemic glucocorticoid metabolism in inflammatory arthritis ⬇️

scientific article published on 17 April 2008

Localized bowel vasculitis: postoperative cyclophosphamide or not?

scientific article published on 01 January 1999

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis

Ly49H+ NK cells migrate to and protect splenic white pulp stroma from murine cytomegalovirus infection.

scientific article

Lymphoid aggregates that resemble tertiary lymphoid organs define a specific pathological subset in metal-on-metal hip replacements

scientific article

Macrophages form a protective cellular barrier in joints

scientific article published on 01 August 2019

Measuring the specific activity of the protein tyrosine phosphatase Lyp

scientific article published on 03 December 2012

Mediation of the proinflammatory cytokine response in rheumatoid arthritis and spondylarthritis by interactions between fibroblast-like synoviocytes and natural killer cells

scientific article published on 01 March 2008

Memory T cells constitute a subset of the human CD8+CD45RA+ pool with distinct phenotypic and migratory characteristics.

scientific article

Mesenchymal stem cells: the fibroblasts' new clothes?

scientific article published on 23 December 2008

Metabolic Checkpoints in Rheumatoid Arthritis

scientific article published on 17 April 2020

Metabolic profiling predicts response to anti-tumor necrosis factor α therapy in patients with rheumatoid arthritis

scientific article published on June 2013

Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes

scientific article published on 01 August 2019

Monocytes/macrophages express chemokine receptor CCR9 in rheumatoid arthritis and CCL25 stimulates their differentiation

scientific article

Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface.

scientific article published on 3 July 2017

New pathogenic insights into rheumatoid arthritis

scientific article published on May 2015

Nonclassical Ly6C(-) monocytes drive the development of inflammatory arthritis in mice.

scientific article published on 16 October 2014

Notch signalling drives synovial fibroblast identity and arthritis pathology

scientific article published on 22 April 2020

Nurse-led care for the management of rheumatoid arthritis: a review of the global literature and proposed strategies for implementation in Africa and the Middle East

scientific article published on 26 August 2020

Oxidised metabolites of the omega-6 fatty acid linoleic acid activate dFOXO

scientific article published on 28 January 2020

Pathogenic stromal cells as therapeutic targets in joint inflammation

scientific article published on 01 December 2018

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

scientific article

Pathways involved in the resolution of inflammatory joint disease

scientific article

Patient and researcher perspectives on facilitating patient and public involvement in rheumatology research

scientific article published on 16 December 2016

Patients' perceptions of their relatives' risk of developing rheumatoid arthritis and of the potential for risk communication, prediction and modulation.

scientific article published on 20 December 2016

Perceptions of first-degree relatives of patients with rheumatoid arthritis about lifestyle modifications and pharmacological interventions to reduce the risk of rheumatoid arthritis development: a qualitative interview study

scientific article published on 06 November 2018

Performance of the 2010 ACR/EULAR criteria for rheumatoid arthritis: comparison with 1987 ACR criteria in a very early synovitis cohort.

scientific article published in February 2011

Pericytes promote selective vessel regression to regulate vascular patterning

scientific journal article

Periodontitis in systemic rheumatic diseases

scientific article published on April 2009

Periodontitis prevalence and serum antibody reactivity to periodontal bacteria in primary Sjögren's syndrome: a pilot study

scientific article published on 8 December 2015

Persistent stromal fibroblast activation is present in chronic tendinopathy.

scientific article published on 25 January 2017

Phosphatidylinositol 3-kinase delta pathway: a novel therapeutic target for Sjögren's syndrome

scientific article published on 24 November 2018

Phototoxicity and fluorotoxicity combine to alter the behavior of neutrophils in fluorescence microscopy based flow adhesion assays

scientific article

Plasma Levels of Eicosapentaenoic Acid Are Associated with Anti-TNF Responsiveness in Rheumatoid Arthritis and Inhibit the Etanercept-driven Rise in Th17 Cell Differentiation in Vitro.

scientific article

Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development

scientific article

Podoplanin negatively regulates CD4+ effector T cell responses

scientific article

Postnatal Deletion of Podoplanin in Lymphatic Endothelium Results in Blood Filling of the Lymphatic System and Impairs Dendritic Cell Migration to Lymph Nodes

scientific article

Pre-symptomatic autoimmunity in rheumatoid arthritis: when does the disease start?

scientific article published on 23 March 2017

Predictive value of antibodies to cyclic citrullinated peptide in patients with very early inflammatory arthritis

scientific article

Predictors of time to revision and clinical outcomes following revision of metal-on-metal hip replacements for adverse reaction to metal debris

scientific article published on December 2014

Priming in response to pro-inflammatory cytokines is a feature of adult synovial but not dermal fibroblasts

scientific article

Prognostic value of comorbidity indices and lung diseases in early rheumatoid arthritis: a UK population-based study

scientific article published on 03 October 2019

Prolonged half-life of verapamil in a case of overdose: implications for therapy

scientific article

Prolonged, granulocyte-macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha

scientific article published on 23 April 2008

Proresolving lipid mediators and mechanisms in the resolution of acute inflammation

scientific article

Prostaglandin D2 regulates CD4+ memory T cell trafficking across blood vascular endothelium and primes these cells for clearance across lymphatic endothelium

scientific article published on 29 June 2011

RGD peptides induce apoptosis by direct caspase-3 activation.

scientific article published on February 1999

Ready-made cellular plugs heal skin wounds

scientific article published on 01 December 2019

Relationship between structural changes and hyperpolarized gas magnetic resonance imaging in chronic obstructive pulmonary disease using computational simulations with realistic alveolar geometry.

scientific article published on June 2009

Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid

scientific article published on 5 August 2015

Report on antibodies submitted to the stromal cell section of HLDA8.

scientific article published on July 2005

Resolution of inflammation: state of the art, definitions and terms

scientific article

Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function

scientific article published on 11 June 2014

Resolving the problem of persistence in the switch from acute to chronic inflammation

scholarly article

Response to: 'Potential roles for tenascin in (very) early diagnosis and treatment of rheumatoid arthritis' by Cutolo et al

scientific article published on 12 February 2019

Response to: 'The autoantibody repertoire in periodontitis: a role in the induction of autoimmunity to citrullinated proteins in rheumatoid arthritis? Antibodies against uncitrullinated peptides seem to occur prior to the antibodies to the correspon

scientific article published on 19 April 2014

Rheumatoid arthritis. The two faces of Rsk2 in hyperplastic disease

scientific article published on 27 January 2015

Rheumatoid fibroblast-like synoviocytes overexpress the chemokine stromal cell-derived factor 1 (CXCL12), which supports distinct patterns and rates of CD4+ and CD8+ T cell migration within synovial tissue

scientific article published on 01 September 2003

Rheumatoid synovial fibroblasts differentiate into distinct subsets in the presence of cytokines and cartilage.

scientific article

Rheumatoid synovial fluid interleukin-17-producing CD4 T cells have abundant tumor necrosis factor-alpha co-expression, but little interleukin-22 and interleukin-23R expression

scientific article

Right target, right place, right time: how understandings of pathogenic mechanisms are informing the treatment of rheumatic diseases

scientific article published on 11 April 2013

Role of CD248 as a potential severity marker in idiopathic pulmonary fibrosis

scientific article

Role of ligands in the activation of LFA-1

scientific article published on 01 April 1997

SAT-LB056 Is AIP a Tumor Suppressor or an Oncogene? AIP as a Novel Regulator of the Oncogene BCL6 in Diffuse Large B Cell Lymphoma

Selective accumulation of virus-specific CD8+ T cells with unique homing phenotype within the human bone marrow

scientific article published on 17 July 2008

Serum amyloid P and fibrosis in systemic sclerosis: comment on the article by Tennent et al

scientific article published on 01 December 2007

Smoke exposure as a determinant of autoantibody titre in 1-antitrypsin deficiency and COPD

scientific article published on 04 June 2010

Splenic stromal cells mediate IL-7 independent adult lymphoid tissue inducer cell survival.

scientific article published in February 2010

Spondyloarthropathy: interleukin 23 and disease modification

scientific article published on May 2015

Spontaneously Resolving Joint Inflammation Is Characterised by Metabolic Agility of Fibroblast-Like Synoviocytes

scientific article published on 26 August 2021

Stroma: fertile soil for inflammation

scientific article

Stroma: the forgotten cells of innate immune memory.

scientific article published in July 2018

Stromal Fibroblasts in Tertiary Lymphoid Structures: A Novel Target in Chronic Inflammation

scientific article

Stromal cell markers are differentially expressed in the synovial tissue of patients with early arthritis.

scientific article published on 9 August 2017

Stromal cells differentially regulate neutrophil and lymphocyte recruitment through the endothelium

scientific article published on November 2010

Stromal cells in chronic inflammation and tertiary lymphoid organ formation

scientific article published on January 2015

Stromal transcriptional profiles reveal hierarchies of anatomical site, serum response and disease and identify disease specific pathways

scientific article published on 25 March 2015

Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss. ⬇️

scientific article published on 22 June 2009

Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis.

scientific article

Synovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritis ⬇️

scientific article published on 18 October 2012

Synovial cell metabolism and chronic inflammation in rheumatoid arthritis

scientific article published on 26 March 2018

Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients

scientific article published on 16 March 2019

Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthritis

scientific article published on January 2006

Synovial tissue research: a state-of-the-art review

scientific article

Synovial tissue research: a state-of-the-art review

scientific article published on 01 September 2017

TNFα regulates cortisol metabolism in vivo in patients with inflammatory arthritis

scholarly article by Dominika E Nanus et al published 2 January 2014 in Annals of the Rheumatic Diseases

Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?

scientific article

Targeting stromal cells in chronic inflammation

scientific article published on February 2007

Targeting the rheumatoid arthritis synovial fibroblast via cyclin dependent kinase inhibition: An early phase trial

scientific article published on 01 June 2020

Targeting the stromal microenvironment in chronic inflammation.

scientific article

The assessment of T-cell apoptosis in synovial fluid.

scientific article published on January 2007

The autoantibody repertoire in periodontitis: a role in the induction of autoimmunity to citrullinated proteins in rheumatoid arthritis?

scientific article published on 23 February 2013

The autoimmune-associated genetic variant PTPN22 R620W enhances neutrophil activation and function in patients with rheumatoid arthritis and healthy individuals

scientific article published on 24 March 2014

The biology of IL-23 and IL-17 and their therapeutic targeting in rheumatic diseases

scientific article

The critical role of interleukin-23 in spondyloarthropathy

scientific article published on August 2013

The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state

scientific article

The impact of inflammation on metabolomic profiles in patients with arthritis

scientific article published on August 2013

The influence of ethnicity on the extent of, and reasons underlying, delay in general practitioner consultation in patients with RA

scientific article published on 26 February 2010

The local physicochemical environment conditions the proinflammatory response of endothelial cells and thus modulates leukocyte recruitment

scientific article published in July 2004

The mesenchymal stem cell marker CD248 (endosialin) is a negative regulator of bone formation in mice.

scientific article

The new aims and scope of Arthritis Research & Therapy

scientific article published on 7 February 2018

The pericyte and stromal cell marker CD248 (endosialin) is required for efficient lymph node expansion

scientific journal article

The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response

scholarly article

The relationship between the presence of anti-cyclic citrullinated peptide antibodies and clinical phenotype in very early rheumatoid arthritis

scientific article

The resolution of inflammation

scientific article published on 30 November 2012

The response of T cells to interleukin-6 is differentially regulated by the microenvironment of the rheumatoid synovial fluid and tissue

scientific article published on 01 November 2011

The role of chemokines in leucocyte-stromal interactions in rheumatoid arthritis

scientific article published on January 2008

The role of leukocyte-stromal interactions in chronic inflammatory joint disease

scientific article

The role of platelet-endothelial cell adhesion molecule-1 in atheroma formation varies depending on the site-specific hemodynamic environment

scientific article published on 31 January 2013

The role of stromal cells in inflammatory bone loss

scientific article

The role of stromal cells in the persistence of chronic inflammation

scientific article published on January 2013

The role of the cysteine-rich region of the beta2 integrin subunit in the leukocyte function-associated antigen-1 (LFA-1, alphaLbeta2, CD11a/CD18) heterodimer formation and ligand binding

scientific article published on 01 December 1998

The role of ultrasound-defined tenosynovitis and synovitis in the prediction of rheumatoid arthritis development.

scientific article published on 3 April 2018

The stromal cell antigen CD248 (endosialin) is expressed on naive CD8+ human T cells and regulates proliferation

scientific article published on 6 April 2011

Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis

scientific article published on 06 February 2020

Thymic function is maintained during Salmonella-induced atrophy and recovery

scientific article published on 19 September 2012

Tissue inflammation signatures point towards resolution in adhesive capsulitis

scientific article published on 01 June 2019

Tonsillar homing of Epstein-Barr virus-specific CD8+ T cells and the virus-host balance

scientific article published on 18 August 2005

Topical glucocorticoid therapy directly induces up-regulation of functional CXCR4 on primed T lymphocytes in the aqueous humor of patients with uveitis

scientific article published in June 2004

Transcriptional Profiling of Synovial Macrophages using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis.

scientific article published on 13 February 2018

Transendothelial migration confers a survival advantage to activated T lymphocytes: role of LFA-1/ICAM-1 interactions

scientific article published on November 2003

Transmigrated neutrophils down-regulate the expression of VCAM-1 on endothelial cells and inhibit the adhesion of flowing lymphocytes

scientific article published on 30 September 2004

Treating very early rheumatoid arthritis

scientific article published on October 2006

Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression

scientific article

Tumour necrosis factor inhibition versus rituximab for patients with rheumatoid arthritis who require biological treatment (ORBIT): an open-label, randomised controlled, non-inferiority, trial

scientific article published on 16 May 2016

Ultrasound guidance allows accurate needle placement and aspiration from small joints in patients with early inflammatory arthritis

scientific article published on 16 April 2003

Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients.

scientific article published on 13 December 2013

Utility of ultrasound joint counts in the prediction of rheumatoid arthritis in patients with very early synovitis

scientific article

What can rheumatologists learn from translational cancer therapy?

scientific article published on January 2013

Why does chronic inflammation persist: An unexpected role for fibroblasts ⬇️

scientific article published on February 17, 2011

Why does chronic inflammatory joint disease persist?

scientific article

Why does inflammation persist: a dominant role for the stromal microenvironment?

scientific article published on 9 December 2002

Why should rheumatologists care about fibroblasts?: Answering questions about tissue tropism and disease persistence

scientific article published on 01 June 2017

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