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List of works by Roland E Kontermann

A Fab-Selective Immunoglobulin-Binding Domain from Streptococcal Protein G with Improved Half-Life Extension Properties

scientific article published on 2 October 2015

A fast and effective determination of the biodistribution and subcellular localization of fluorescent immunoliposomes in freshly excised animal organs

scientific article

A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor

scientific article published on October 2014

A novel expression and purification system for the production of enzymatic and biologically active human granzyme B.

scientific article published on 22 June 2011

Activatable bispecific liposomes bearing fibroblast activation protein directed single chain fragment/Trastuzumab deliver encapsulated cargo into the nuclei of tumor cells and the tumor microenvironment simultaneously

scientific article published on 24 March 2017

Alternative antibody formats.

scientific article published on April 2010

An Antibody Fusion Protein for Cancer Immunotherapy Mimicking IL-15 trans-Presentation at the Tumor Site ⬇️

scientific article published on April 6, 2012

An EGF receptor targeting Ranpirnase-diabody fusion protein mediates potent antitumour activity in vitro and in vivo

scientific article

An optimized antibody-single-chain TRAIL fusion protein for cancer therapy.

scientific article published on 11 April 2016

Antagonistic TNF receptor one-specific antibody (ATROSAB): receptor binding and in vitro bioactivity

scientific article

Antagonists of TNF action: clinical experience and new developments

scientific article published on March 2009

Antibody phage display technologies with special reference to angiogenesis

scientific article

Antibody–cytokine fusion proteins ⬇️

scientific article published on March 16, 2012

Antitumor Activity of a Mesenchymal Stem Cell Line Stably Secreting a Tumor-Targeted TNF-Related Apoptosis-Inducing Ligand Fusion Protein

scientific article

Biodistribution of a bispecific single-chain diabody and its half-life extended derivatives

scientific article published on 23 July 2009

Bispecific antibodies for cancer immunotherapy: Current perspectives

scientific article

Bispecific single-chain diabody-immunoliposomes targeting endoglin (CD105) and fibroblast activation protein (FAP) simultaneously

scientific article

Bispecific single-chain diabody-mediated killing of endoglin-positive endothelial cells by cytotoxic T lymphocytes

scientific article published on March 2004

CAR-J cells for antibody discovery and lead optimization of TCR-like immunoglobulins

scientific article published on 01 January 2020

Cell selection and characterization of a novel human endothelial cell specific nanobody

scientific article

Dataset on FAP-induced emergence of spontaneous metastases and on the preparation of activatable FAP-targeting immunoliposomes to detect the metastases

scientific article

Design, selection and optimization of an anti-TRAIL-R2/anti-CD3 bispecific antibody able to educate T cells to recognize and destroy cancer cells

scientific article published on 06 August 2018

Diabody-Ig: a novel platform for the generation of multivalent and multispecific antibody molecules

scientific article published on 03 May 2019

Dual targeting strategies with bispecific antibodies ⬇️

scientific article published on March 1, 2012

Duokines: a novel class of dual-acting co-stimulatory molecules acting in cis or trans

scientific article published on 01 August 2018

Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration

scientific article published on 10 October 2016

Evaluating combinations of costimulatory antibody-ligand fusion proteins for targeted cancer immunotherapy

scientific article published on 30 May 2013

Expression and purification of recombinant antibody formats and antibody fusion proteins

scientific article published on January 2014

Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential

scientific article

Genetic delivery of an immunoRNase by an oncolytic adenovirus enhances anticancer activity

scientific article published on 12 November 2014

Half-life extended biotherapeutics

scientific article published on 11 March 2016

Half-life extension of a single-chain diabody by fusion to domain B of staphylococcal protein A ⬇️

scientific article published on January 11, 2012

Humanization of a mouse monoclonal antibody directed against a cell surface-exposed epitope of membrane-associated heat shock protein 70 (Hsp70).

scientific article

Immuno-LipoTRAIL: Targeted delivery of TRAIL-functionalized liposomal nanoparticles

scientific article published on 7 May 2014

Immunoliposomes for cancer therapy.

scientific article

Improved monovalent TNF receptor 1-selective inhibitor with novel heterodimerizing Fc

scientific article published on 31 March 2019

In vivo near-infrared fluorescence imaging of FAP-expressing tumors with activatable FAP-targeted, single-chain Fv-immunoliposomes

scientific article published on 5 May 2014

Inhibition of HER3 activation and tumor growth with a human antibody binding to a conserved epitope formed by domain III and IV.

scientific article published on 19 April 2017

Inhibition of cell proliferation and induction of apoptosis by novel tetravalent peptides inhibiting DNA binding of E2F.

scientific article

Intrabodies as therapeutic agents

scientific article published in October 2004

Isolation from phage display libraries of lysine-deficient human epidermal growth factor variants for directional conjugation as targeting ligands

scientific article published in December 2003

Isolation of endothelial cell-specific human antibodies from a novel fully synthetic scFv library

scientific article published in April 2004

Monovalent TNF receptor 1-selective antibody with improved affinity and neutralizing activity

scientific article published on 02 October 2018

Murine endoglin-specific single-chain Fv fragments for the analysis of vascular targeting strategies in mice

scientific article

Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells

scientific article

Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2.

scientific article

Pharmacokinetic properties of IgG and various Fc fusion proteins in mice

scientific article published on 29 October 2015

Phenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization

scientific article

Potential of activatable FAP-targeting immunoliposomes in intraoperative imaging of spontaneous metastases

scientific article published on 23 February 2016

Recombinant bispecific antibodies for cancer therapy

scientific article

Recombinant bispecific antibodies for cellular cancer immunotherapy

scientific article published on August 2007

Recombinant bispecific antibodies for the targeting of adenoviruses to CEA-expressing tumour cells: a comparative analysis of bacterially expressed single-chain diabody and tandem scFv

scientific article published in June 2004

Specific gene delivery to liver sinusoidal and artery endothelial cells

scientific article published on 24 July 2013

Strategies for extended serum half-life of protein therapeutics

scientific article published on 20 August 2011

Strategies to extend plasma half-lives of recombinant antibodies

scientific article published on January 2009

Tetravalent antibody-scTRAIL fusion proteins with improved properties

scientific article

Tumor-antigen-binding bispecific antibodies for cancer treatment

scientific article

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