List of works - Malabika Sen

Analysis of oncogenic activities of protein kinase D1 in head and neck squamous cell carcinoma

Antitumor mechanisms of targeting the PDK1 pathway in head and neck cancer

scientific article

Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death

scientific article

Caspase-8 mutations in head and neck cancer confer resistance to death receptor-mediated apoptosis and enhance migration, invasion, and tumor growth

scientific article

Crystallization and preliminary X-ray analysis of cyclophilin from Leishmania donovani

scientific article published on 28 September 2002

First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.

scientific article published on 20 June 2012

Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3

scientific article published on 16 September 2009

HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell lines

scientific article

High Content Imaging Assays for IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines

scientific article published in January 2018

High-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines

scientific article

Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies

scientific article

JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth.

scientific article

Lack of toxicity of a STAT3 decoy oligonucleotide.

scientific article

Mechanism of action of selective inhibitors of IL-6 induced STAT3 pathway in head and neck cancer cell lines

scientific article

Nucleic acid-based approaches to STAT inhibition

scientific article

Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors

scientific article

Orthotopic expression of human 15-lipoxygenase (LO)-1 in the dorsolateral prostate of normal wild-type C57BL/6 mouse causes PIN-like lesions.

scientific article published on 25 July 2006

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response

scientific article published on 16 November 2015

Phase 1 study of EGFR-antisense DNA, cetuximab, and radiotherapy in head and neck cancer with preclinical correlatives

scientific article published on 06 October 2018

Polyunsaturated fatty acid metabolizing 15-Lipoxygenase-1 (15-LO-1) expression in normal and tumorigenic human bladder tissues

scientific article published in March 2008

Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane

scientific article published on 23 June 2016

Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer

scientific article published on 23 March 2017

STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma

scientific article published on 7 June 2016

STAT3 oligonucleotide inhibits tumor angiogenesis in preclinical models of squamous cell carcinoma

scientific article (publication date: 2014)

Systemic administration of a cyclic signal transducer and activator of transcription 3 (STAT3) decoy oligonucleotide inhibits tumor growth without inducing toxicological effects

scientific article published on 18 March 2014

Targeting Stat3 abrogates EGFR inhibitor resistance in cancer.

scientific article

The Jigsaw Puzzle Model: Search for Conformational Specificity in Protein Interiors ⬇️

scientific article published on October 10, 2003

Toxicity, pharmacokinetics and metabolism of a novel inhibitor of IL-6-induced STAT3 activation

scientific article published on 24 October 2016

Ultrasound Targeted Microbubble Destruction-Mediated Delivery of a Transcription Factor Decoy Inhibits STAT3 Signaling and Tumor Growth

scientific article

Utility of 3'-[(18)F]fluoro-3'-deoxythymidine as a PET tracer to monitor response to gene therapy in a xenograft model of head and neck carcinoma ⬇️

scientific article published on January 5, 2013

List of works by Malabika Sen

Analysis of oncogenic activities of protein kinase D1 in head and neck squamous cell carcinoma

Antitumor mechanisms of targeting the PDK1 pathway in head and neck cancer

Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death

Caspase-8 mutations in head and neck cancer confer resistance to death receptor-mediated apoptosis and enhance migration, invasion, and tumor growth

Crystallization and preliminary X-ray analysis of cyclophilin from Leishmania donovani

First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.

Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3

HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell lines

High Content Imaging Assays for IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines

High-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines

Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies

JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth.

Lack of toxicity of a STAT3 decoy oligonucleotide.

Mechanism of action of selective inhibitors of IL-6 induced STAT3 pathway in head and neck cancer cell lines

Nucleic acid-based approaches to STAT inhibition

Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors

Orthotopic expression of human 15-lipoxygenase (LO)-1 in the dorsolateral prostate of normal wild-type C57BL/6 mouse causes PIN-like lesions.

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response

Phase 1 study of EGFR-antisense DNA, cetuximab, and radiotherapy in head and neck cancer with preclinical correlatives

Polyunsaturated fatty acid metabolizing 15-Lipoxygenase-1 (15-LO-1) expression in normal and tumorigenic human bladder tissues

Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane

Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer

STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma

STAT3 oligonucleotide inhibits tumor angiogenesis in preclinical models of squamous cell carcinoma

Systemic administration of a cyclic signal transducer and activator of transcription 3 (STAT3) decoy oligonucleotide inhibits tumor growth without inducing toxicological effects

Targeting Stat3 abrogates EGFR inhibitor resistance in cancer.

The Jigsaw Puzzle Model: Search for Conformational Specificity in Protein Interiors ⬇️

Toxicity, pharmacokinetics and metabolism of a novel inhibitor of IL-6-induced STAT3 activation

Ultrasound Targeted Microbubble Destruction-Mediated Delivery of a Transcription Factor Decoy Inhibits STAT3 Signaling and Tumor Growth

Utility of 3'-[(18)F]fluoro-3'-deoxythymidine as a PET tracer to monitor response to gene therapy in a xenograft model of head and neck carcinoma ⬇️