List of works by Robert M Hoffman

3-Deazaadenosine, a stabilizer of whole-blood homocysteine content, does not interfere with the single-enzyme homocysteine assay while totally inhibiting the enzyme conversion homocysteine immunoassay

scientific article

3-dimensional tissue is formed from cancer cells in vitro on Gelfoam®, but not on Matrigel™.

scientific article published on August 2014

A Color-coded Imageable Syngeneic Mouse Model of Stromal-cell Recruitment by Metastatic Lymphoma.

scientific article published on September 2015

A Mouse Model of Fluorescent Protein-expressing Disseminated Peritoneal Lymphoma for Fluorescence-guided Surgery

scientific article published on September 2016

A clinically relevant, syngeneic model of spontaneous, highly metastatic B16 mouse melanoma

scientific article published on December 2010

A dual-color genetically engineered mouse model for multispectral imaging of the pancreatic microenvironment

scientific article published on August 2013

A genetically engineered oncolytic adenovirus decoys and lethally traps quiescent cancer stem-like cells in S/G2/M phases.

scientific article published on 30 September 2013

A novel alkylating agent, glufosfamide, enhances the activity of gemcitabine in vitro and in vivo

scientific article published on August 2007

A novel anionic-phosphate-platinum complex effectively targets an undifferentiated pleomorphic sarcoma better than cisplatinum and doxorubicin in a patient-derived orthotopic xenograft (PDOX)

scientific article published on 28 June 2017

A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts

scientific article

A novel red fluorescent protein orthotopic pancreatic cancer model for the preclinical evaluation of chemotherapeutics

scientific article published on July 2003

A patient-derived orthotopic xenograft (PDOX) mouse model of a cisplatinum-resistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications for precision oncology

scientific article published on 8 July 2017

A patient-derived orthotopic xenograft (PDOX) nude-mouse model precisely identifies effective and ineffective therapies for recurrent leiomyosarcoma

scientific article published on 23 February 2019

A rapid HPLC method for the measurement of ultra-low plasma methionine concentrations applicable to methionine depletion therapy

scientific article published in January 2005

A rapid imageable in vivo metastasis assay for circulating tumor cells.

scientific article

A simultaneous colorimetric assay of free and protein-coupled polyethylene glycol

scientific article published in February 2003

A transgenic red fluorescent protein-expressing nude mouse for color-coded imaging of the tumor microenvironment

scientific article published on February 2009

Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models

scientific article published on 18 December 2015

Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model.

scientific article published on 19 October 2015

Advantages of fluorescence-guided laparoscopic surgery of pancreatic cancer labeled with fluorescent anti-carcinoembryonic antigen antibodies in an orthotopic mouse model

scientific article

Aging hair follicles rejuvenated by transplantation to a young subcutaneous environment

scientific article published on 03 March 2016

An LED light source and novel fluorophore combinations improve fluorescence laparoscopic detection of metastatic pancreatic cancer in orthotopic mouse models

scientific article

An imageable highly metastatic orthotopic red fluorescent protein model of pancreatic cancer

scientific article published on January 2004

Analysis of Stroma Labeling During Multiple Passage of a Sarcoma Imageable Patient-Derived Orthotopic Xenograft (iPDOX) in Red Fluorescent Protein Transgenic Nude Mice.

scientific article

Anti-metastatic Efficacy of Traditional Chinese Medicine (TCM) Ginsenoside Conjugated to a VEFGR-3 Antibody on Human Gastric Cancer in an Orthotopic Mouse Model

scientific article published on March 2017

Antimetastatic Efficacy of the Combination of Caffeine and Valproic Acid on an Orthotopic Human Osteosarcoma Cell Line Model in Nude Mice

scientific article published on March 2017

Antimetastatic efficacy of oral 5-FU imaged by green fluorescent protein in real time.

scientific article published in January 2003

Application of GFP imaging in cancer

scientific article

Automated enzymatic assay for homocysteine

scientific article published in June 2003

Bax-induction gene therapy of pancreatic cancer.

scientific article published in August 2002

Biological ablation of sentinel lymph node metastasis in submucosally invaded early gastrointestinal cancer

scientific article

Blockage of autophagy pathway enhances Salmonella tumor-targeting

scientific article published on 22 March 2016

Bone Marrow Mesenchymal Stem Cells Reverse Liver Damage in a Carbon Tetrachloride-induced Mouse Model of Chronic Liver Injury

scientific article published on January 2016

Broad selective efficacy of rMETase and PEG-rMETase on cancer cells in vitro.

scientific article published on March 2010

Broad selective efficacy of recombinant methioninase and polyethylene glycol-modified recombinant methioninase on cancer cells In Vitro

scientific article

CXC-chemokine/CXCR2 biological axis promotes angiogenesis in vitro and in vivo in pancreatic cancer

scientific article

Cancer cells mimic in vivo spatial-temporal cell-cycle phase distribution and chemosensitivity in 3-dimensional Gelfoam® histoculture but not 2-dimensional culture as visualized with real-time FUCCI imaging.

scientific article

Cancer metastasis directly eradicated by targeted therapy with a modified Salmonella typhimurium

scientific article

Cell-cycle fate-monitoring distinguishes individual chemosensitive and chemoresistant cancer cells in drug-treated heterogeneous populations demonstrated by real-time FUCCI imaging

scientific article published on January 2015

Cell-cycle-dependent drug-resistant quiescent cancer cells induce tumor angiogenesis after chemotherapy as visualized by real-time FUCCI imaging.

scientific article published on 11 August 2016

Cellular dynamics visualized in live cells in vitro and in vivo by differential dual-color nuclear-cytoplasmic fluorescent-protein expression

scientific article published on June 2004

Cervical Cancer Patient-Derived Orthotopic Xenograft (PDOX) Is Sensitive to Cisplatinum and Resistant to Nab-paclitaxel

scientific article published in January 2017

Chapter 2. Color-coded fluorescent mouse models of cancer cell interactions with blood vessels and lymphatics

scientific article

Chemoprevention by Quercetin of Oral Squamous Cell Carcinoma by Suppression of the NF-κB Signaling Pathway in DMBA-treated Hamsters

scientific article published on August 2017

Chemotherapy targets the hair-follicle vascular network but not the stem cells

scientific article published on 13 July 2006

Choline-Deficient-Diet-Induced Fatty Liver Is a Metastasis-Resistant Microenvironment

scientific article

Circulating half-life of PEGylated recombinant methioninase holoenzyme is highly dose dependent on cofactor pyridoxal-5'-phosphate

scientific article

Color coding cancer cells with fluorescent proteins to visualize in vivo cellular interaction in metastatic colonies.

scientific article published on November 2004

Color-Coded Imaging of Breast Cancer Metastatic Niche Formation in Nude Mice

scientific article

Color-Coded Imaging of Syngeneic Orthotopic Malignant Lymphoma Interacting with Host Stromal Cells During Metastasis

scientific article

Color-coded Imaging Enables Fluorescence-guided Surgery to Resect the Tumor Along with the Tumor Microenvironment in a Syngeneic Mouse Model of EL-4 Lymphoma

scientific article

Color-coded Live Imaging of Heterokaryon Formation and Nuclear Fusion of Hybridizing Cancer Cells

scientific article

Color-coded fluorescence imaging of lymph-node metastasis, angiogenesis, and its drug-induced inhibition

scientific article published in March 2014

Color-coded fluorescent protein imaging of angiogenesis: the AngioMouse models

scientific article published on January 2008

Color-coded imaging of splenocyte-pancreatic cancer cell interactions in the tumor microenvironment ⬇️

scientific article

Color-coded imaging of spontaneous vessel anastomosis in vivo.

scientific article

Color-coded intravital imaging demonstrates a transforming growth factor-β (TGF-β) antagonist selectively targets stromal cells in a human pancreatic-cancer orthotopic mouse model

scientific article

Color-coded real-time subcellular fluorescence imaging of the interaction between cancer and host cells in live mice

scientific article

Combination Efficacy of Astragalus membranaceus and Curcuma wenyujin at Different Stages of Tumor Progression in an Imageable Orthotopic Nude Mouse Model of Metastatic Human Ovarian Cancer Expressing Red Fluorescent Protein.

scientific article published on June 2015

Combination Treatment With Sorafenib and Everolimus Regresses a Doxorubicin-resistant Osteosarcoma in a PDOX Mouse Model

scientific article published on 01 September 2019

Combination of gemcitabine and docetaxel regresses both gastric leiomyosarcoma proliferation and invasion in an imageable patient-derived orthotopic xenograft (iPDOX) model.

scientific article published on 20 April 2017

Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model.

scientific article

Combining Tumor-Selective Bacterial Therapy with Salmonella typhimurium A1-R and Cancer Metabolism Targeting with Oral Recombinant Methioninase Regressed an Ewing's Sarcoma in a Patient-Derived Orthotopic Xenograft Model

scientific article published on 01 January 2018

Common bile duct injection as a novel method for establishing red fluorescent protein (RFP)-expressing human pancreatic cancer in nude mice.

scientific article published on 9 March 2006

Comparative chemosensitivity of circulating human prostate cancer cells and primary cancer cells

scientific article

Comparison of GFP-Expressing Imageable Mouse Models of Human Esophageal Squamous Cell Carcinoma Established in Various Anatomical Sites

scientific article published on September 2015

Comparison of Tumor Recurrence After Resection of Highly- and Poorly-Metastatic Triple-negative Breast Cancer in Orthotopic Nude-Mouse Models.

scientific article published on January 2017

Comparison of UVB and UVC effects on the DNA damage-response protein 53BP1 in human pancreatic cancer

scientific article published on October 2014

Comparison of a chimeric anti-carcinoembryonic antigen antibody conjugated with visible or near-infrared fluorescent dyes for imaging pancreatic cancer in orthotopic nude mouse models

scientific article published on December 2013

Comparison of efficacy and toxicity of traditional Chinese medicine (TCM) herbal mixture LQ and conventional chemotherapy on lung cancer metastasis and survival in mouse models

scientific article

Comparison of efficacy of Salmonella typhimurium A1-R and chemotherapy on stem-like and non-stem human pancreatic cancer cells

scientific article published on 06 August 2013

Comparison of in vitro invasiveness of high- and low-metastatic triple-negative human breast cancer visualized by color-coded imaging

scientific article

Comparison of nestin-expressing multipotent stem cells in the tongue fungiform papilla and vibrissa hair follicle

scientific article

Comparison of the selective targeting efficacy of Salmonella typhimurium A1-R and VNP20009 on the Lewis lung carcinoma in nude mice

scientific article

Complementarity of ultrasound and fluorescence imaging in an orthotopic mouse model of pancreatic cancer

scientific article

Complementarity of variable-magnification and spectral-separation fluorescence imaging systems for noninvasive detection of metastasis and intravital detection of single cancer cells in mouse models

scientific article published in February 2015

Cover Image, Volume 118, Number 1, January 2017.

scientific article published in January 2017

Cryopreservation of Hair-Follicle Associated Pluripotent (HAP) Stem Cells Maintains Differentiation and Hair-Growth Potential

scientific article

Cryopreservation of the Hair Follicle Maintains Pluripotency of Nestin-Expressing Hair Follicle-Associated Pluripotent Stem Cells

scientific article published on 15 April 2015

Current status and future perspectives of fluorescence-guided surgery for cancer

scientific article

Decreased Expression of Tumor-suppressor Gene LKB1 Correlates with Poor Prognosis in Human Gastric Cancer

scientific article published on March 2016

Detection of colon cancer metastases with fluorescence laparoscopy in orthotopic nude mouse models

scientific article

Detection of early colorectal cancer imaged with peanut agglutinin-immobilized fluorescent nanospheres having surface poly(N-vinylacetamide) chains

scientific article

Determination of clonality of metastasis by cell-specific color-coded fluorescent-protein imaging

scientific article published on November 2003

Development of a clinically-precise mouse model of rectal cancer

scientific article

Development of a green fluorescent protein metastatic-cancer chick-embryo drug-screen model

scientific article published in January 2004

Development of real-time subcellular dynamic multicolor imaging of cancer-cell trafficking in live mice with a variable-magnification whole-mouse imaging system

scientific article published on April 2006

Development of the transgenic cyan fluorescent protein (CFP)-expressing nude mouse for "Technicolor" cancer imaging

scientific article

Direct evidence that PTHrP expression promotes prostate cancer progression in bone.

scientific article

Direct external imaging of nascent cancer, tumor progression, angiogenesis, and metastasis on internal organs in the fluorescent orthotopic model

scientific article

Discovery of HAP Stem Cells

scientific article published in January 2016

Disintegrin targeting of an αvβ3 integrin-over-expressing high-metastatic human osteosarcoma with echistatin inhibits cell proliferation, migration, invasion and adhesion in vitro

scientific article published on 16 June 2016

Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF.

scientific article

Dissecting p53 tumor suppressor functions in vivo

scientific article

Doxorubicin-resistant pleomorphic liposarcoma with PDGFRA gene amplification is targeted and regressed by pazopanib in a patient-derived orthotopic xenograft mouse model

scientific article published on 22 May 2018

Dual-color fluorescence imaging distinguishes tumor cells from induced host angiogenic vessels and stromal cells ⬇️

scientific article published on November 12, 2003

Dual-color imaging of angiogenesis and its inhibition in bone and soft tissue sarcoma

scientific article

Dual-color imaging of nascent angiogenesis and its inhibition in liver metastases of pancreatic cancer.

scientific article

Dual-color imaging of nascent blood vessels vascularizing pancreatic cancer in an orthotopic model demonstrates antiangiogenesis efficacy of gemcitabine

scientific article published on 28 February 2006

Dual-color imaging of nuclear-cytoplasmic dynamics, viability, and proliferation of cancer cells in the portal vein area

scientific article published on January 2006

Dual-color-coded imaging of viable circulating prostate carcinoma cells reveals genetic exchange between tumor cells in vivo, contributing to highly metastatic phenotypes

scientific article published on 16 January 2006

Dynamic color-coded fluorescence imaging of the cell-cycle phase, mitosis, and apoptosis demonstrates how caffeine modulates cisplatinum efficacy

scientific article published on November 2013

Dynamic subcellular imaging of cancer cell mitosis in the brain of live mice

scientific article

Early Reporting of Apoptosis by Real-time Imaging of Cancer Cells Labeled with Green Fluorescent Protein in the Nucleus and Red Fluorescent Protein in the Cytoplasm

scientific article published on May 2015

Early-age-dependent selective decrease of differentiation potential of hair-follicle-associated pluripotent (HAP) stem cells to beating cardiac-muscle cells

scientific article published on 18 July 2016

Effective Metabolic Targeting of Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models with Recombinant Methioninase.

scientific article

Effective fluorescence-guided surgery of liver metastasis using a fluorescent anti-CEA antibody

scientific article published on 3 October 2016

Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model.

scientific article published on 07 June 2016

Effects of siRNA Silencing of TUG1 and LCAL6 Long Non-coding RNAs on Patient-derived Xenograft of Non-small Cell Lung Cancer

scientific article published in January 2018

Efficacy In Vitro of Caffeine and Valproic Acid on Patient-Derived Undifferentiated Pleomorphic Sarcoma and Rhabdomyosarcoma Cell Lines

scientific article

Efficacy against lung metastasis with a tumor-targeting mutant of Salmonella typhimurium in immunocompetent mice

scientific article published on January 2012

Efficacy comparison of traditional Chinese medicine LQ versus gemcitabine in a mouse model of pancreatic cancer

scientific article published on September 2013

Efficacy of Salmonella typhimurium A1-R versus chemotherapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX).

scientific article published in July 2014

Efficacy of Tumor-Targeting Salmonella A1-R on a Melanoma Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Model

scientific article

Efficacy of Tumor-Targeting Salmonella typhimurium A1-R against Malignancies in Patient-Derived Orthotopic Xenograft (PDOX) Murine Models

scientific article published on 16 June 2019

Efficacy of a Cell-Cycle Decoying Killer Adenovirus on 3-D Gelfoam®-Histoculture and Tumor-Sphere Models of Chemo-Resistant Stomach Carcinomatosis Visualized by FUCCI Imaging

scientific article

Efficacy of a genetically-modified Salmonella typhimurium in an orthotopic human pancreatic cancer in nude mice.

scientific article

Efficacy of camptothecin analog DX-8951f (Exatecan Mesylate) on human pancreatic cancer in an orthotopic metastatic model

scientific article

Efficacy of dietary antioxidants combined with a chemotherapeutic agent on human colon cancer progression in a fluorescent orthotopic mouse model

scientific article

Efficacy of glycogen synthase kinase-3β targeting against osteosarcoma via activation of β-catenin

scientific article published on 20 October 2016

Efficacy of the Combination of a PARP Inhibitor and UVC on Cancer Cells as Imaged by Focus Formation by the DNA Repair-related Protein 53BP1 Linked to Green Fluorescent Protein

scientific article published on August 2016

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models.

scientific article

Efficacy of tumor-targeting Salmonella typhimurium A1-R on nude mouse models of metastatic and disseminated human ovarian cancer

scientific article

Embryonic development of hair follicle pluripotent stem (hfPS) cells ⬇️

scientific article published on August 4, 2010

Enhanced Metastatic Recurrence Via Lymphatic Trafficking of a High-Metastatic Variant of Human Triple-Negative Breast Cancer After Surgical Resection in Orthotopic Nude Mouse Models.

scientific article published on 14 September 2016

Enhanced resection of orthotopic red-fluorescent-protein-expressing human glioma by fluorescence-guided surgery in nude mice

scientific article

Enhancement of Wound Healing by the Traditional Chinese Medicine Herbal Mixture Sophora flavescens in a Rat Model of Perianal Ulceration

scientific article published on July 2017

Enhancing magnetic resonance imaging tumor detection with fluorescence intensity and lifetime imaging

scientific article

Eradication of melanoma in vitro and in vivo via targeting with a Killer-Red-containing telomerase-dependent adenovirus

scientific article

Eradication of osteosarcoma by fluorescence-guided surgery with tumor labeling by a killer-reporter adenovirus

scientific article published on 19 October 2015

Eribulin Suppressed Cisplatinum- and Doxorubicin-resistant Recurrent Lung Metastatic Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model

scientific article published on 01 September 2019

Eribulin regresses a doxorubicin-resistant Ewing's sarcoma with a FUS-ERG fusion and CDKN2A-deletion in a patient-derived orthotopic xenograft (PDOX) nude mouse model.

scientific article published on 6 July 2017

Essential role for activation of the Polycomb group (PcG) protein chromatin silencing pathway in metastatic prostate cancer

scientific article published on 15 August 2006

Establishment of a patient-derived orthotopic Xenograft (PDOX) model of HER-2-positive cervical cancer expressing the clinical metastatic pattern

scientific article

Experimental Curative Fluorescence-guided Surgery of Highly Invasive Glioblastoma Multiforme Selectively Labeled With a Killer-reporter Adenovirus.

scientific article published on 21 April 2015

Extensive Hair Shaft Growth after Mouse Whisker Follicle Isolation, Cryopreservation and Transplantation in Nude Mice

scientific article published on 30 December 2015

Extensive Hair-Shaft Elongation by Isolated Mouse Whisker Follicles in Very Long-Term Gelfoam® Histoculture

scientific article published on 30 September 2015

Fluorescence laparoscopy imaging of pancreatic tumor progression in an orthotopic mouse model

scientific article

Fluorescence-Guided Surgery of Liver Metastasis in Orthotopic Nude-Mouse Models

scientific article published on October 2015

Fluorescence-guided Surgery with Splenic Preservation Prevents Tumor Recurrence in an Orthotopic Nude-mouse Model of Human Pancreatic Cancer.

scientific article published in February 2018

Fluorescence-guided surgery allows for more complete resection of pancreatic cancer, resulting in longer disease-free survival compared with standard surgery in orthotopic mouse models

scientific article

Fluorescence-guided surgery and fluorescence laparoscopy for gastrointestinal cancers in clinically-relevant mouse models

scientific article published on 19 February 2013

Fluorescence-guided surgery improves outcome in an orthotopic osteosarcoma nude-mouse model

scientific article

Fluorescence-guided surgery in combination with UVC irradiation cures metastatic human pancreatic cancer in orthotopic mouse models

scientific article (publication date: 2014)

Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence.

scientific article published on 28 September 2016

Fluorescence-guided surgery of human colon cancer increases complete resection resulting in cures in an orthotopic nude mouse model

scientific article

Fluorescence-guided surgery of human prostate cancer experimental bone metastasis in nude mice using anti-CEA DyLight 650 for tumor illumination.

scientific article

Fluorescence-guided surgery of prostate cancer bone metastasis

scientific article

Fluorescence-guided surgery of retroperitoneal-implanted human fibrosarcoma in nude mice delays or eliminates tumor recurrence and increases survival compared to bright-light surgery

scientific article

Fluorescence-guided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA), that highlights the tumor, improves surgical resection and increases survival in orthotopic mouse models of human pancreatic cancer

scientific article

Fluorescence-guided surgery, but not bright-light surgery, prevents local recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) model resistant to neoadjuvant chemotherapy (NAC)

scientific article published on 7 March 2015

Fluorescent LYVE-1 antibody to image dynamically lymphatic trafficking of cancer cells in vivo

scientific article published on 18 January 2008

Fluorescent proteins enhance UVC PDT of cancer cells

scientific article

Fluorescent-Antibody Targeting of Insulin-Like Growth Factor-1 Receptor Visualizes Metastatic Human Colon Cancer in Orthotopic Mouse Models

scientific article published on 5 January 2016

Fluorescently labeled chimeric anti-CEA antibody improves detection and resection of human colon cancer in a patient-derived orthotopic xenograft (PDOX) nude mouse model

scientific article

Fluorophore-conjugated anti-CEA antibody for the intraoperative imaging of pancreatic and colorectal cancer

scientific article

From hair to heart: nestin-expressing hair-follicle-associated pluripotent (HAP) stem cells differentiate to beating cardiac muscle cells

scientific article

GFP labeling kinetics of triple-negative human breast cancer by a killer-reporter adenovirus in 3D Gelfoam® histoculture.

scientific article published on 23 February 2017

Gemcitabine combined with docetaxel precisely regressed a recurrent leiomyosarcoma peritoneal metastasis in a patient-derived orthotopic xenograft (PDOX) model

scientific article published on 16 January 2019

Gene therapy of pancreatic cancer with green fluorescent protein and tumor necrosis factor-related apoptosis-inducing ligand fusion gene expression driven by a human telomerase reverse transcriptase promoter

scientific article published in August 2003

Genetic Recombination Between Stromal and Cancer Cells Results in Highly Malignant Cells Identified by Color-Coded Imaging in a Mouse Lymphoma Model.

scientific article published on 17 April 2017

Growth of doxorubicin-resistant undifferentiated spindle-cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase.

scientific article

Hair follicle-associated-pluripotent (HAP) stem cells

scientific article

Hair follicle-derived blood vessels vascularize tumors in skin and are inhibited by Doxorubicin

scientific article

Hand-held high-resolution fluorescence imaging system for fluorescence-guided surgery of patient and cell-line pancreatic tumors growing orthotopically in nude mice

scientific article

Heterogeneous cell-cycle behavior in response to UVB irradiation by a population of single cancer cells visualized by time-lapse FUCCI imaging.

scientific article published on June 2015

High Efficacy of Pazopanib on an Undifferentiated Spindle-Cell Sarcoma Resistant to First-Line Therapy Is Identified With a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model

scientific article

High antimetastatic efficacy of MEN4901/T-0128, a novel camptothecin carboxymethyldextran conjugate

scientific article

High correlation of whole-body red fluorescent protein imaging and magnetic resonance imaging on an orthotopic model of pancreatic cancer

scientific article published on November 2005

High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model.

scientific article published on 20 April 2016

High efficiency genetic modification of hair follicles and growing hair shafts

scientific article

High lung-metastatic variant of human osteosarcoma cells, selected by passage of lung metastasis in nude mice, is associated with increased expression of α(v)β(3) integrin

scientific article published on September 2013

High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models.

scientific article published on 23 September 2016

High-level expression and bulk crystallization of recombinant L-methionine gamma-lyase, an anticancer agent

scientific article published on 13 July 2005

High-metastatic triple-negative breast-cancer variants selected in vivo become chemoresistant in vitro

scientific article published on 26 January 2017

High-resolution magnetic resonance imaging of the efficacy of the cytosine analogue 1-[2-C-cyano-2-deoxy-beta-D-arabino-pentofuranosyl]-N(4)-palmitoyl cytosine (CS-682) in a liver-metastasis athymic nude mouse model ⬇️

scientific article published on May 15, 2003

Homogeneous enzymatic colorimetric assay for total cysteine

scientific article

Homogeneous, nonradioactive, enzymatic assay for plasma pyridoxal 5-phosphate.

scientific article published in September 2002

Human hair follicle pluripotent stem (hfPS) cells promote regeneration of peripheral-nerve injury: an advantageous alternative to ES and iPS cells

scientific article published in August 2009

Human hair-follicle associated pluripotent (hHAP) stem cells differentiate to cardiac-muscle cells

scientific article published on 23 November 2016

Human tumor growth in nude mice is associated with decreased plasma cysteine and homocysteine

scientific article

Hypoxia Enhances Differentiation of Hair Follicle-Associated-Pluripotent (HAP) Stem Cells to Cardiac-Muscle Cells

scientific article published on 14 September 2016

Imaging Nuclear-Cytoplasmic Dynamics in Primary and Metastatic Colon Cancer in Nude Mice

scientific article

Imaging UVC-induced DNA damage response in models of minimal cancer

scientific article published in November 2013

Imaging exosome transfer from breast cancer cells to stroma at metastatic sites in orthotopic nude-mouse models

scientific article published on 17 August 2012

Imaging nuclear - cytoplasm dynamics of cancer cells in the intravascular niche of live mice

scientific article published on October 2013

Imaging of nucleolar dynamics during the cell cycle of cancer cells in live mice

scientific article

Imaging of primary and metastatic pancreatic cancer using a fluorophore-conjugated anti-CA19-9 antibody for surgical navigation

scientific article

Imaging of the interaction of cancer cells and the lymphatic system

scientific article published on 28 June 2011

Imaging the Interaction of Pancreatic Cancer and Stellate Cells in the Tumor Microenvironment during Metastasis

scientific article published on May 2015

Imaging the Role of Multinucleate Pancreatic Cancer Cells and Cancer-Associated Fibroblasts in Peritoneal Metastasis in Mouse Models

scientific article

Imaging the efficacy of UVC irradiation on superficial brain tumors and metastasis in live mice at the subcellular level

scientific article published on February 2013

Imaging the inhibition by anti-β1 integrin antibody of lung seeding of single osteosarcoma cells in live mice.

scientific article published on 14 March 2012

Imaging the interaction of αv integrin-GFP in osteosarcoma cells with RFP-expressing host stromal cells and tumor-scaffold collagen in the primary and metastatic tumor microenvironment

scientific article published on 26 August 2018

Imaging the microenvironment of pancreatic cancer patient-derived orthotopic xenografts (PDOX) growing in transgenic nude mice expressing GFP, RFP, or CFP.

scientific article

Imaging the recruitment of cancer-associated fibroblasts by liver-metastatic colon cancer

scientific article

Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves

scientific article

Implanted hair-follicle-associated pluripotent (HAP) stem cells encapsulated in polyvinylidene fluoride membrane cylinders promote effective recovery of peripheral nerve injury.

scientific article published on 8 September 2017

Improved Resection and Outcome of Colon-Cancer Liver Metastasis with Fluorescence-Guided Surgery Using In Situ GFP Labeling with a Telomerase-Dependent Adenovirus in an Orthotopic Mouse Model

scientific article

Improved disease-free survival and overall survival after fluorescence-guided surgery of liver metastasis in an orthotopic nude mouse model.

scientific article published on 12 August 2015

In Vivo Isolation of a Highly-aggressive Variant of Triple-negative Human Breast Cancer MDA-MB-231 Using Serial Orthotopic Transplantation

scientific article published on August 2016

In Vivo Selection of Intermediately- and Highly-Malignant Variants of Triple-negative Breast Cancer in Orthotopic Nude Mouse Models

scientific article published on December 2016

In vitro/in vivo biorecognition of lectin-immobilized fluorescent nanospheres for human colorectal cancer cells

scientific article

In vivo color-coded imaging of the interaction of colon cancer cells and splenocytes in the formation of liver metastases.

scientific article published in December 2006

In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation.

scientific article

In vivo fluorescence imaging of gastrointestinal stromal tumors using fluorophore-conjugated anti-KIT antibody

scientific article

In vivo fluorescence imaging reveals the promotion of mammary tumorigenesis by mesenchymal stromal cells

scientific article

In vivo fluorescence of medullary carcinoma of the thyroid: a technology with potential to improve visualization of malignant tissue at surgical resection.

scientific article

In vivo gene transfer between interacting human osteosarcoma cell lines is associated with acquisition of enhanced metastatic potential

scientific article

In vivo imaging of nuclear-cytoplasmic deformation and partition during cancer cell death due to immune rejection

scientific article

In vivo imaging of pancreatic cancer with fluorescent proteins in mouse models

scientific article published in January 2012

In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation

scientific article published on 17 August 2009

Increased expression of apoptosis inhibitor protein XIAP contributes to anoikis resistance of circulating human prostate cancer metastasis precursor cells.

scientific article

Individualized doxorubicin sensitivity testing of undifferentiated soft tissue sarcoma (USTS) in a patient-derived orthotopic xenograft (PDOX) model demonstrates large differences between patients

scientific article published on 31 January 2018

Induction of Metastasis by Low-dose Gemcitabine in a Pancreatic Cancer Orthotopic Mouse Model: An Opposite Effect of Chemotherapy

scientific article published on 01 October 2019

Induction of cancer metastasis by cyclophosphamide pretreatment of host mice: an opposite effect of chemotherapy

scientific article

Inhibition and eradication of human glioma with tumor-targeting Salmonella typhimurium in an orthotopic nude-mouse model

scientific article published in February 2012

Inhibition of metastasis of circulating human prostate cancer cells in the chick embryo by an extracellular matrix produced by foreskin fibroblasts in culture.

scientific article

Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R

scientific article

Intra-arterial administration of tumor-targeting Salmonella typhimurium A1-R regresses a cisplatin-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model

scientific article published on 11 May 2017

Intraoperative imaging of metastatic lymph nodes using a fluorophore-conjugated antibody in a HER2/neu-expressing orthotopic breast cancer mouse model

scientific article published on February 2013

Intraperitoneal administration of tumor-targeting Salmonella typhimurium A1-R inhibits disseminated human ovarian cancer and extends survival in nude mice

scientific article published on May 2015

Invading cancer cells are predominantly in G0/G1 resulting in chemoresistance demonstrated by real-time FUCCI imaging

scientific article

In vivo serial selection of human pancreatic cancer cells in orthotopic mouse models produces high metastatic variants irrespective of Kras status

scientific article published on 05 April 2013

Isoproterenol directs hair follicle-associated pluripotent (HAP) stem cells to differentiate in vitro to cardiac muscle cells which can be induced to form beating heart-muscle tissue sheets

scientific article

KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer

scientific article published on May 2012

Knockdown of the β(1) integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis

scientific article

Labeling the Stroma of a Patient-Derived Orthotopic Xenograft (PDOX) Mouse Model of Undifferentiated Pleomorphic Soft-Tissue Sarcoma With Red Fluorescent Protein for Rapid Non-Invasive Imaging for Drug Screening.

scientific article

Long-Term Extensive Ectopic Hair Growth on the Spinal Cord of Mice from Transplanted Whisker Follicles

scientific article published on 5 August 2015

Long-working-distance fluorescence microscope with high-numerical-aperture objectives for variable-magnification imaging in live mice from macro- to subcellular

scientific article

MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model

scientific article published on 05 May 2018

MEK inhibitors cobimetinib and trametinib, regressed a gemcitabine-resistant pancreatic-cancer patient-derived orthotopic xenograft (PDOX)

scientific article published on 7 May 2017

MUC1 selectively targets human pancreatic cancer in orthotopic nude mouse models.

scientific article

Magnetic resonance and fluorescence imaging of doxorubicin-loaded nanoparticles using a novel in vivo model

scientific article published on 3 July 2010

Major liver resection stimulates stromal recruitment and metastasis compared with repeated minor resection

scientific article

Marker expression in circulating cancer cells of pancreatic cancer patients

scientific article published on June 2010

Metastatic recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) nude mouse model is inhibited by neoadjuvant chemotherapy in combination with fluorescence-guided surgery with an anti-CA 19-9-conjugated fluorophore

scientific article

Metronomic gemcitabine in combination with sunitinib inhibits multisite metastasis and increases survival in an orthotopic model of pancreatic cancer

scientific article

Modified Liver Hanging Maneuver for En-bloc Right-sided Hepatectomy Combined with Total Caudate Lobectomy for Colon-Cancer Liver Metastasis and Hepatocellular Carcinoma

scientific article published in April 2016

Moesin Expression Is Associated with Glioblastoma Cell Proliferation and Invasion

scientific article

Monotherapy with a tumor-targeting mutant of S. typhimurium inhibits liver metastasis in a mouse model of pancreatic cancer

scientific article

Monotherapy with a tumor-targeting mutant of Salmonella typhimurium cures orthotopic metastatic mouse models of human prostate cancer

scholarly article

Multi-color palette of fluorescent proteins for imaging the tumor microenvironment of orthotopic tumorgraft mouse models of clinical pancreatic cancer specimens

scientific article published on July 2012

Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function

scientific article published on 2 June 2008

Multipotent nestin-expressing stem cells capable of forming neurons are located in the upper, middle and lower part of the vibrissa hair follicle

scientific article published on 23 August 2012

Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons

scientific article

Nanoparticle albumin-bound-paclitaxel: a limited improvement under the current therapeutic paradigm of pancreatic cancer

scientific article published on May 2015

Nascent blood vessels in the skin arise from nestin-expressing hair-follicle cells

scholarly article

Near infra-red photoimmunotherapy with anti-CEA-IR700 results in extensive tumor lysis and a significant decrease in tumor burden in orthotopic mouse models of pancreatic cancer

scientific article

Near-infrared-conjugated humanized anti-carcinoembryonic antigen antibody targets colon cancer in an orthotopic nude-mouse model.

scientific article published in October 2017

Neddylation Inhibition Activates the Extrinsic Apoptosis Pathway through ATF4-CHOP-DR5 Axis in Human Esophageal Cancer Cells

scientific article published on 16 March 2016

Neoadjuvant chemoradiotherapy of pancreatic cancer induces a favorable immunogenic tumor microenvironment associated with increased major histocompatibility complex class I-related chain A/B expression.

scientific article published on 12 June 2017

Nestin expression in hair follicle sheath progenitor cells

scientific article published on 6 August 2003

Nestin-Expressing Stem Cells Promote Nerve Growth in Long-Term 3-Dimensional Gelfoam®-Supported Histoculture ⬇️

scientific article

Nestin-expressing interfollicular blood vessel network contributes to skin transplant survival and wound healing

scientific article published in May 2010

Nestin-linked green fluorescent protein transgenic nude mouse for imaging human tumor angiogenesis

scientific article published on June 2005

Non-toxic Efficacy of the Combination of Caffeine and Valproic Acid on Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models.

scientific article published on September 2016

Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model

scientific article published on 10 March 2019

Optically imageable metastatic model of human breast cancer

scientific article published in January 2002

Oral 5-FU is a more effective antimetastatic agent than UFT.

scientific article

Oral Recombinant Methioninase Overcomes Colorectal-cancer Liver Metastasis Resistance to the Combination of 5-Fluorouracil and Oxaliplatinum in a Patient-derived Orthotopic Xenograft Mouse Model

scientific article published on 01 September 2019

Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma

scientific article published on 01 September 2019

Orthotopic Implantation of Intact Tumor Tissue Leads to Metastasis of OCUM-2MD3 Human Gastric Cancer in Nude Mice Visualized in Real Time by Intravital Fluorescence Imaging

scientific article published on May 2016

Osimertinib Regresses an EGFR-Mutant Cisplatinum- Resistant Lung Adenocarcinoma Growing in the Brain in Nude Mice

scientific article published on 23 February 2019

Osteosarcoma cells enhance angiogenesis visualized by color-coded imaging in the in vivo Gelfoam® assay

scientific article

Ovarian tumor attachment, invasion, and vascularization reflect unique microenvironments in the peritoneum: insights from xenograft and mathematical models.

scientific article

Overactivated neddylation pathway as a therapeutic target in lung cancer.

scientific article

PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates

scientific article published in September 2004

Paclitaxel nanosuspensions for targeted chemotherapy - nanosuspension preparation, characterization, and use.

scientific article published on 25 April 2013

Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation

scientific article

Parathyroid hormone related-protein promotes epithelial-to-mesenchymal transition in prostate cancer

scientific article published on 22 January 2014

Parathyroid hormone-related protein as a novel tumor marker in pancreatic adenocarcinoma

scientific article

Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy.

scientific article published on 28 September 2016

Patient-derived orthotopic xenograft (PDOX) mouse model of adult rhabdomyosarcoma invades and recurs after resection in contrast to the subcutaneous ectopic model.

scientific article published on 10 November 2016

Patient-derived orthotopic xenograft (PDOX) nude mouse model of soft-tissue sarcoma more closely mimics the patient behavior in contrast to the subcutaneous ectopic model.

scientific article

Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy, and tumor-targeting S. typhimurium A1-R is superior to first-line chemotherapy

scientific article published on 27 April 2018

Patient-derived orthotopic xenograft models of sarcoma

scientific article published on 19 October 2019

Peripheral-Nerve and Spinal-Cord Regeneration in Mice Using Hair-Follicle-Associated Pluripotent (HAP) Stem Cells

scientific article published in January 2016

Peritoneal Metastases in a Patient-derived Orthotopic Xenograft (PDOX) Model of Colon Cancer Imaged Non-invasively via Red Fluorescent Protein Labeled Stromal Cells

scientific article published on 01 July 2019

Pharmacokinetics, methionine depletion, and antigenicity of recombinant methioninase in primates

scientific article published in March 2004

Photoimmunotherapy Inhibits Tumor Recurrence After Surgical Resection on a Pancreatic Cancer Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model

scientific article published on 17 April 2015

Photoimmunotherapy lowers recurrence after pancreatic cancer surgery in orthotopic nude mouse models

scientific article published on 19 February 2015

Physicochemical and pharmacokinetic characterization of highly potent recombinant L-methionine gamma-lyase conjugated with polyethylene glycol as an antitumor agent

scientific article published in March 2006

Pioglitazone, an agonist of PPARγ, reverses doxorubicin-resistance in an osteosarcoma patient-derived orthotopic xenograft model by downregulating P-glycoprotein expression

scientific article published on 22 August 2019

Polyethylene glycol (PEG) linked to near infrared (NIR) dyes conjugated to chimeric anti-carcinoembryonic antigen (CEA) antibody enhances imaging of liver metastases in a nude-mouse model of human colon cancer

scientific article

Potent and highly selective hypoxia-activated achiral phosphoramidate mustards as anticancer drugs.

scientific article

Potential of immunotherapy for sarcoma

scientific article published on 27 February 2017

Precise navigation surgery of tumours in the lung in mouse models enabled by in situ fluorescence labelling with a killer-reporter adenovirus

scientific article

Primer dosing of S. typhimurium A1-R potentiates tumor-targeting and efficacy in immunocompetent mice

scientific article

Prolonged dormancy and site-specific growth potential of cancer cells spontaneously disseminated from nonmetastatic breast tumors as revealed by labeling with green fluorescent protein ⬇️

scientific article published on September 1, 2003

Protein carboxyl amidation increases the potential extent of protein polyethylene glycol conjugation

scientific article

Protocols for Cryopreservation of Intact Hair Follicle That Maintain Pluripotency of Nestin-Expressing Hair-Follicle-Associated Pluripotent (HAP) Stem Cells

scientific article published on January 2016

Protocols for Ectopic Hair Growth from Transplanted Whisker Follicles on the Spinal Cord of Mice

scientific article published in January 2016

Protocols for Gelfoam(®) Histoculture of Hair-Shaft-Producing Mouse Whisker Follicles Containing Nestin-GFP-Expressing Hair-Follicle-Associated Pluripotent (HAP) Stem Cells for Long Time Periods.

scientific article published in January 2016

Ratiometric activatable cell-penetrating peptides label pancreatic cancer, enabling fluorescence-guided surgery, which reduces metastases and recurrence in orthotopic mouse models

scientific article

Real Time Metastatic Route Tracking of Orthotopic PC-3-GFP Human Prostate Cancer Using Intravital Imaging

scientific article published on 7 October 2015

Real-Time GFP Intravital Imaging of the Differences in Cellular and Angiogenic Behavior of Subcutaneous and Orthotopic Nude-Mouse Models of Human PC-3 Prostate Cancer

scientific article

Real-Time In Vivo Confocal Fluorescence Imaging of Prostate Cancer Bone-Marrow Micrometastasis Development at the Cellular Level in Nude Mice.

scientific article published on 18 March 2016

Real-time GFP imaging of spontaneous HT-1080 fibrosarcoma lung metastases

scientific article published on January 1, 2003

Real-time Non-invasive Spectral Imaging of Orthotopic Red Fluorescent Protein-expressing Lung Tumor Growth in Nude Mice.

scientific article

Real-time fluorescence imaging of the DNA damage repair response during mitosis

scientific article

Real-time imaging of apoptosis induction of human breast cancer cells by the traditional Chinese medicinal herb tubeimu.

scientific article

Real-time imaging of individual fluorescent-protein color-coded metastatic colonies in vivo

scientific article published in January 2003

Real-time imaging of single cancer-cell dynamics of lung metastasis

scientific article

Real-time imaging of tumor progression in a fluorescent orthotopic mouse model of thyroid cancer

scientific article published on November 2010

Real-time imaging of tumor-cell shedding and trafficking in lymphatic channels

scientific article published on September 2007

Real-time imaging of αv integrin molecular dynamics in osteosarcoma cells in vitro and in vivo

scientific article

Real-time in vivo dual-color imaging of intracapillary cancer cell and nucleus deformation and migration

scientific article published in May 2005

Real-time in vivo green fluorescent protein imaging of a murine leishmaniasis model as a new tool for Leishmania vaccine and drug discovery

scientific article published on 22 October 2008

Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model.

scientific article

Real-time whole-body imaging of an orthotopic metastatic prostate cancer model expressing red fluorescent protein

scientific article published in March 2005

Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models

scientific article published on 12 December 2017

Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model

scientific article

Recombinant methioninase in combination with doxorubicin (DOX) overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma.

scientific article published on 3 January 2018

Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis

scientific article published on 19 January 2017

Recruitment of Cancer-Associated Fibroblasts and Blood Vessels by Orthotopic Liver Tumors Imaged in Red Fluorescent Protein (RFP) Transgenic Nude Mice

scientific article published in November 2015

Regorafenib regressed a doxorubicin-resistant Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude mouse model

scientific article published on 13 February 2019

Regorafenib regresses an imatinib-resistant recurrent gastrointestinal stromal tumor (GIST) with a mutation in exons 11 and 17 in a patient-derived orthotopic xenograft (PDOX) nude mouse model.

scientific article published on 15 January 2018

Salmonella typhimurium A1-R targeting of a chemotherapy-resistant BRAF-V600E melanoma in a patient-derived orthotopic xenograft (PDOX) model is enhanced in combination with either vemurafenib or temozolomide.

scientific article published on 16 June 2017

Salmonella typhimurium A1-R tumor targeting in immunocompetent mice is enhanced by a traditional Chinese medicine herbal mixture.

scientific article published in May 2013

Selective antimetastatic activity of cytosine analog CS-682 in a red fluorescent protein orthotopic model of pancreatic cancer ⬇️

scientific article published on September 1, 2003

Selective efficacy of zoledronic acid on metastasis in a patient-derived orthotopic xenograph (PDOX) nude-mouse model of human pancreatic cancer

scientific article published on 14 November 2014

Selective induction of apoptosis in the hamster flank sebaceous gland organ by a topical liposome 5-alpha-reductase inhibitor: a treatment strategy for acne

scientific article published in February 2010

Selective metastatic tumor labeling with green fluorescent protein and killing by systemic administration of telomerase-dependent adenoviruses

scientific article

Selective methioninase-induced trap of cancer cells in S/G2 phase visualized by FUCCI imaging confers chemosensitivity

scientific article

Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers.

scientific article published on 26 January 2010

Simultaneous color‐coded imaging to distinguish cancer “stem‐like” and non‐stem cells in the same tumor ⬇️

scientific article published on November 1, 2010

Single cell time-lapse imaging of focus formation by the DNA damage-response protein 53BP1 after UVC irradiation of human pancreatic cancer cells

scientific article published in April 2013

Sorafenib and Palbociclib Combination Regresses a Cisplatinum-resistant Osteosarcoma in a PDOX Mouse Model

scientific article published on 01 August 2019

Spatial-temporal FUCCI imaging of each cell in a tumor demonstrates locational dependence of cell cycle dynamics and chemoresponsiveness

scientific article

Specific route mapping visualized with GFP of single-file streaming contralateral and systemic metastasis of Lewis lung carcinoma cells beginning within hours of orthotopic implantation [correction of implantion].

scientific article published in August 2013

Specific tumor labeling enhanced by polyethylene glycol linkage of near infrared dyes conjugated to a chimeric anti-carcinoembryonic antigen antibody in a nude mouse model of human pancreatic cancer

scientific article

Splenectomy is associated with an aggressive tumor growth pattern and altered host immunity in an orthotopic syngeneic murine pancreatic cancer model.

scientific article published on 28 September 2017

Stem-like and non-stem human pancreatic cancer cells distinguished by morphology and metastatic behavior

scientific article

Subcellular real-time imaging of the efficacy of temozolomide on cancer cells in the brain of live mice.

scientific article

Surgically-Induced Multi-organ Metastasis in an Orthotopic Syngeneic Imageable Model of 4T1 Murine Breast Cancer.

scientific article published on September 2015

Survival efficacy of adjuvant cytosine-analogue CS-682 in a fluorescent orthotopic model of human pancreatic cancer

scientific article published on March 2004

Synergistic Inhibitory Effect of Traditional Chinese Medicine Astragaloside IV and Curcumin on Tumor Growth and Angiogenesis in an Orthotopic Nude-Mouse Model of Human Hepatocellular Carcinoma

scientific article published on February 2017

Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer

scientific article published in April 2015

Systemic targeting of primary bone tumor and lung metastasis of high-grade osteosarcoma in nude mice with a tumor-selective strain of Salmonella typhimurium

scientific article published on 20 March 2009

Tail spontaneous metastatic mouse model: comparison of metastatic potential of orthotopic and heterotopic models imaged by GFP and RFP protein.

scientific article

Targeted therapy with a Salmonella typhimurium leucine-arginine auxotroph cures orthotopic human breast tumors in nude mice

scientific article published in August 2006

Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention.

scientific article published on 29 November 2017

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models

scientific article published on 22 February 2016

Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma

scientific article

Temozolomide combined with irinotecan caused regression in an adult pleomorphic rhabdomyosarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model.

scientific article published on 24 March 2017

Temozolomide regresses a doxorubicin-resistant undifferentiated spindle-cell sarcoma patient-derived orthotopic xenograft (PDOX): precision-oncology nude-mouse model matching the patient with effective therapy

scientific article published on 08 May 2018

The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model

scientific article published on 09 July 2019

The Use of Living Cancer Cells Expressing Green Fluorescent Protein in the Nucleus and Red Fluorescence Protein in the Cytoplasm for Real-time Confocal Imaging of Chromosome and Cytoplasmic Dynamics During Mitosis

scientific article published on May 2015

The advantages of hair follicle pluripotent stem cells over embryonic stem cells and induced pluripotent stem cells for regenerative medicine

scientific article published on October 1, 2010

The bisphosphonate olpadronate inhibits skeletal prostate cancer progression in a green fluorescent protein nude mouse model

scientific article published on April 2006

The camptothecin derivative CPT-11 inhibits angiogenesis in a dual-color imageable orthotopic metastatic nude mouse model of human colon cancer.

scientific article published on March 2007

The combination of 5-FU, leucovorin and CPT-11 (FOLFIRI) prolongs survival through inhibition of metastasis in an orthotopic model of colon cancer.

scientific article published on February 2010

The combination of gemcitabine and docetaxel arrests a doxorubicin-resistant dedifferentiated liposarcoma in a patient-derived orthotopic xenograft model

scientific article published on 11 June 2019

The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model

scientific article published on 04 January 2019

The combination of olaratumab with gemcitabine and docetaxel arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft mouse model

scientific article published on 30 March 2019

The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing's sarcoma with a FUS-ERG fusion and CDKN2A deletion: Direction for third-line patient therap

scientific article published on 8 September 2017

The cyan fluorescent protein (CFP) transgenic mouse as a model for imaging pancreatic exocrine cells

scientific article

The disintegrin echistatin in combination with doxorubicin targets high-metastatic human osteosarcoma overexpressing ανβ3 integrin in chick embryo and nude mouse models

scientific article

The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago.

scientific article

The role of the intravascular microenvironment in spontaneous metastasis development

scientific article published on June 2010

The tumor-educated-macrophage increase of malignancy of human pancreatic cancer is prevented by zoledronic acid

scientific article

Therapeutic Cell-Cycle-Decoy Efficacy of a Telomerase-Dependent Adenovirus in an Orthotopic Model of Chemotherapy-Resistant Human Stomach Carcinomatosis Peritonitis Visualized With FUCCI Imaging.

scientific article

Therapeutic Efficacy of the Traditional Chinese Medicine Baishaoqiwu on TNBS-induced Colitis is Associated with Down-regulation of the TLR4/MyD88/NF-κB Signaling Pathway

scientific article published in January 2016

Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models

scientific article published on 7 September 2015

Toward Curative Fluorescence-Guided Surgery of Pancreatic Cancer

scientific article published on May 2015

Toxicology and efficacy of tumor-targeting Salmonella typhimurium A1-R compared to VNP 20009 in a syngeneic mouse tumor model in immunocompetent mice.

scientific article published on 3 May 2017

Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model

scientific article published on 05 April 2019

Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model

Traditional Chinese Medicine Curcumin Sensitizes Human Colon Cancer to Radiation by Altering the Expression of DNA Repair-related Genes

scientific article published in January 2018

Traditional Chinese medicine herbal mixture LQ arrests FUCCI-expressing HeLa cells in G₀/G₁ phase in 2D plastic, 2.5D Matrigel, and 3D Gelfoam culture visualized with FUCCI imaging

scientific article published on March 2015

Transdifferentiation of glioblastoma cells into vascular endothelial cells

scientific article

Transgenic nude mouse with ubiquitous green fluorescent protein expression as a host for human tumors.

scientific article published in December 2004

Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis

scientific article published on August 2002

Tumor cells genetically labeled with GFP in the nucleus and RFP in the cytoplasm for imaging cellular dynamics

scientific article published in June 2006

Tumor imaging technologies in mouse models

scientific article

Tumor imaging with multicolor fluorescent protein expression

scientific article published on 25 February 2011

Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore.

scientific article published on 25 January 2018

Tumor-Targeting Salmonella typhimurium A1-R Arrests a Chemo-Resistant Patient Soft-Tissue Sarcoma in Nude Mice.

scientific article published on 3 August 2015

Tumor-Targeting Salmonella typhimurium A1-R Promotes Tumoricidal CD8+ T Cell Tumor Infiltration and Arrests Growth and Metastasis in a Syngeneic Pancreatic-Cancer Orthotopic Mouse Model.

scientific article published on 19 June 2017

Tumor-Targeting Salmonella typhimurium A1-R Sensitizes Melanoma With a BRAF-V600E Mutation to Vemurafenib in a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model

scientific article published on 20 January 2017

Tumor-Targeting Salmonella typhimurium A1-R in Combination with Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived Mouse Models

scientific article published on 5 June 2015

Tumor-educated macrophages promote tumor growth and peritoneal metastasis in an orthotopic nude mouse model of human pancreatic cancer.

scientific article

Tumor-sealing Surgical Orthotopic Implantation of Human Colon Cancer in Nude Mice Induces Clinically-relevant Metastases Without Early Peritoneal Carcinomatosis

scientific article published on 01 August 2019

Tumor-selective, adenoviral-mediated GFP genetic labeling of human cancer in the live mouse reports future recurrence after resection

scientific article published on 15 August 2011

Tumor-specific cell-cycle decoy by Salmonella typhimurium A1-R combined with tumor-selective cell-cycle trap by methioninase overcome tumor intrinsic chemoresistance as visualized by FUCCI imaging

scientific article published on 06 May 2016

Tumor-specific fluorescence antibody imaging enables accurate staging laparoscopy in an orthotopic model of pancreatic cancer

scientific article

Tumor-targeting Salmonella typhimurium A1-R Inhibits Osteosarcoma Angiogenesis in the In Vivo Gelfoam® Assay Visualized by Color-coded Imaging.

scientific article published in January 2018

Tumor-targeting Salmonella typhimurium A1-R arrests a doxorubicin-resistant PDGFRA-amplified patient-derived orthotopic xenograft mouse model of pleomorphic liposarcoma

scientific article published on 22 June 2018

Tumor-targeting Salmonella typhimurium A1-R arrests growth of breast-cancer brain metastasis

scientific article published on February 2015

Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: Decoy, trap and kill ch

scientific article

Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic xenograft (PDOX) model

scientific article

Tumor-targeting Salmonella typhimurium A1-R decoys quiescent cancer cells to cycle as visualized by FUCCI imaging and become sensitive to chemotherapy

scientific article

Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model.

scientific article published on 07 February 2016

Tumor-targeting Salmonella typhimurium A1-R inhibits human prostate cancer experimental bone metastasis in mouse models

scientific article published on 28 September 2015

Tumor-targeting Salmonella typhimurium A1-R overcomes nab-paclitaxel resistance in a cervical cancer PDOX mouse model

scientific article published on 05 April 2019

Tumor-targeting Salmonella typhimurium A1-R prevents experimental human breast cancer bone metastasis in nude mice

scientific article

Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug

scientific article published on 20 December 2016

Tumor-targeting Salmonella typhimurium A1-R suppressed an imatinib-resistant gastrointestinal stromal tumor with c-kit exon 11 and 17 mutations

scientific article published on 06 June 2018

Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models

scientific article

Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium

scientific article

UV light killing efficacy of fluorescent protein-expressing cancer cells in vitro and in vivo

scientific article

Upregulation of thrombospondin-1 and angiogenesis in an aggressive human pancreatic cancer cell line selected for high metastasis

scientific article

Use of αv Integrin Linked to GFP to Image Molecular Dynamics in Trafficking Cancer-Cell Emboli

scientific article published on 18 May 2016

Use of αv Integrin Linked to Green Fluorescent Protein in Osteosarcoma Cells and Confocal Microscopy to Image Molecular Dynamics During Lung Metastasis in Nude Mice

scientific article published on August 2016

VEGF receptor antisense therapy inhibits angiogenesis and peritoneal dissemination of human gastric cancer in nude mice

scientific article published on February 2002

VEGF-C ShRNA inhibits pancreatic cancer growth and lymphangiogenesis in an orthotopic fluorescent nude mouse model.

scientific article published on February 2013

Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model

scientific article published on 28 September 2016

Vessel destruction by tumor-targeting Salmonella typhimurium A1-R is enhanced by high tumor vascularity

scientific article

Viable circulating metastatic cells produced in orthotopic but not ectopic prostate cancer models.

scientific article published in July 2003

Visualization of nascent tumor angiogenesis in lung and liver metastasis by differential dual-color fluorescence imaging in nestin-linked-GFP mice

scientific article published on 30 November 2006

Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression

scientific article

Whole-body subcellular multicolor imaging of tumor-host interaction and drug response in real time

scientific article

siRNA Targeting of MDR1 Reverses Multidrug Resistance in a Nude Mouse Model of Doxorubicin-resistant Human Hepatocellular Carcinoma

scientific article published on June 2016

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