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List of works by Graça Almeida-Porada

A Stro-1(+) human universal stromal feeder layer to expand/maintain human bone marrow hematopoietic stem/progenitor cells in a serum-free culture system.

scientific article published in October 2006

A human bone marrow mesodermal-derived cell population with hemogenic potential.

scientific article published on 2 February 2018

A human stromal-based serum-free culture system supports the ex vivo expansion/maintenance of bone marrow and cord blood hematopoietic stem/progenitor cells

scientific article published in July 2005

A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential

scientific article

AC133, a novel marker for human hematopoietic stem and progenitor cells

scientific journal article

Adult mesenchymal stem cells: a pluripotent population with multiple applications

scientific article published on September 2006

Adult stem cell plasticity and methods of detection

scientific article

Altered production of GM-CSF and IL-8 in cytomegalovirus-infected, IL-1-primed umbilical cord endothelial cells

scientific article published on 01 November 1997

Bioactivity of immobilized EGF on self-assembled monolayers: optimization of the immobilization process.

scientific article

Bone Marrow Endothelial Cells Influence Function and Phenotype of Hematopoietic Stem and Progenitor Cells after Mixed Neutron/Gamma Radiation ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2019

Bone marrow stem cells and liver regeneration

scientific article

Boosting Hematopoietic Engraftment after in Utero Transplantation through Vascular Niche Manipulation

scientific article

CD34+ human marrow cells that express low levels of Kit protein are enriched for long-term marrow-engrafting cells

scientific article published on 01 May 1996

Characterization and functionality of cardiac progenitor cells in congenital heart patients

scientific article published on 17 January 2011

Characterization of naturally-occurring humoral immunity to AAV in sheep

scientific article

Clinical and molecular characterization of a re-established line of sheep exhibiting hemophilia A.

scientific article

Consensus statement from the first international conference for in utero stem cell transplantation and gene therapy

scientific article published on 10 February 2015

Correction: A human bone marrow mesodermal-derived cell population with hemogenic potential

scientific article published on 01 July 2018

Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation

scientific article published on 01 June 2000

Cotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in utero

scientific article published on 01 October 1999

Cytomegalovirus as a cause of pancytopenia

scientific article

Definition of early progenitors and functional maturation of human natural killer cells: requirements for cytocidal activity

scientific article published on 01 January 1998

Detection of human cells in human/sheep chimeric lambs with in vitro human stroma-forming potential

scientific article published on 01 February 1996

Development and characterization of a novel CD34 monoclonal antibody that identifies sheep hematopoietic stem/progenitor cells

scientific article published on December 2008

Development and characterization of recombinant ovine coagulation factor VIII

scientific article

Differences amid bone marrow and cord blood hematopoietic stem/progenitor cell division kinetics

scientific article published on July 2009

Differentiative potential of human metanephric mesenchymal cells

scientific article published on 01 December 2002

Distinct contribution of human cord blood-derived endothelial colony forming cells to liver and gut in a fetal sheep model

scientific article published on 2 August 2012

Docosahexaenoic acid induces dose dependent cell death in an early undifferentiated subtype of acute myeloid leukemia cell line

scientific article published on 03 February 2009

Dynamic cell-cell interactions between cord blood haematopoietic progenitors and the cellular niche are essential for the expansion of CD34+, CD34+CD38- and early lymphoid CD7+ cells.

scientific article published in February 2010

Early fetal gene delivery utilizes both central and peripheral mechanisms of tolerance induction

scientific article published on 8 April 2008

Efficient generation of human hepatocytes by the intrahepatic delivery of clonal human mesenchymal stem cells in fetal sheep

scientific article published on 01 December 2007

Engraftment of cultured human hematopoietic cells in sheep

scientific article published on 01 May 1998

EphB2 isolates a human marrow stromal cell subpopulation with enhanced ability to contribute to the resident intestinal cellular pool

scientific article published on 14 February 2013

Evaluating Interaction of Cord Blood Hematopoietic Stem/Progenitor Cells with Functionally Integrated Three-Dimensional Microenvironments.

scientific article published on 23 February 2018

Evaluation of Cytotoxic and Genotoxic Effects of Extremely Low-frequency Electromagnetic Field on Mesenchymal Stromal Cells.

scientific article published on 18 May 2018

Evaluation of gene delivery strategies to efficiently overexpress functional HLA-G on human bone marrow stromal cells

scientific article published on September 2014

Evaluation of serum-free culture conditions able to support the ex vivo expansion and engraftment of human hematopoietic stem cells in the human-to-sheep xenograft model

scientific article published on 01 October 2000

Ex vivo expanded cord blood cells provide rapid engraftment in fetal sheep but lack long-term engrafting potential

scientific article published on 01 June 2002

Exposure of the Bone Marrow Microenvironment to Simulated Solar and Galactic Cosmic Radiation Induces Biological Bystander Effects on Human Hematopoiesis.

scientific article published on 26 April 2018

Expression levels of the PiT-2 receptor explain, in part, the gestational age-dependent alterations in transduction efficiency after in utero retroviral-mediated gene transfer

scientific article published on March 2012

Factors determining the risk of inadvertent retroviral transduction of male germ cells after in utero gene transfer in sheep

scientific article

Formation of human hepatocytes by human hematopoietic stem cells in sheep

scientific article published in July 2004

Gene therapy: the promise of a permanent cure

scientific article published in November 2013

Generation of functional natural killer and dendritic cells in a human stromal-based serum-free culture system designed for cord blood expansion

scientific article

Generation of tissue-specific cells from MSC does not require fusion or donor-to-host mitochondrial/membrane transfer

scientific article published on 16 September 2008

Gestational age of recipient determines pattern and level of transgene expression following in utero retroviral gene transfer.

scientific article published on February 2005

HCMV protein LUNA is required for viral reactivation from latently infected primary CD14⁺ cells

scientific article

Hematopoietic stem cells: from the bone to the bioreactor

scientific article

Hemophilia A: an ideal disease to correct in utero ⬇️

scientific article

Human bone marrow CD34- cells engraft in vivo and undergo multilineage expression that includes giving rise to CD34+ cells

scientific article published on 01 April 1998

Human cytomegalovirus alters interleukin-6 production by endothelial cells

scientific article published on 01 January 1994

Human haematopoietic stem cells that mediate long-term in vivo engraftment are not susceptible to infection by human cytomegalovirus.

scientific article

Human natural killer cell development in a xenogeneic culture system

scientific article published on 01 September 2002

Human thymic stroma supports human natural killer (NK) cell development from immature progenitors

scientific article published on 01 June 1998

In utero stem cell transplantation and gene therapy: rationale, history, and recent advances toward clinical application

scientific article

In utero transfer and expression of exogenous genes in sheep

scientific article published on 01 January 2000

In vitro and in vivo assessment of direct effects of simulated solar and galactic cosmic radiation on human hematopoietic stem/progenitor cells

scientific article

In vivo generation of beta-cell-like cells from CD34(+) cells differentiated from human embryonic stem cells

scientific article

In vivo haematopoietic potential of human neural stem cells

scientific article published on 01 July 2005

Indocyanine green loaded hyaluronan-derived nanoparticles for fluorescence-enhanced surgical imaging of pancreatic cancer

scientific article published on 8 January 2018

Induction of notch signaling by immobilization of jagged-1 on self-assembled monolayers.

scientific article published on 23 September 2009

Initial CD34+ cell-enrichment of cord blood determines hematopoietic stem/progenitor cell yield upon ex vivo expansion.

scientific article published in July 2011

Integration pattern of HIV-1 based lentiviral vector carrying recombinant coagulation factor VIII in Sk-Hep and 293T cells.

scientific article published on 2 September 2010

Isolation, characterization, and biologic features of bone marrow endothelial cells

scientific article published on October 1996

KDR receptor: a key marker defining hematopoietic stem cells

scientific article

Kinetic analysis of the ex vivo expansion of human hematopoietic stem/progenitor cells.

scientific article published in March 2006

Kinetics of engraftment of CD34− and CD34+ cells from mobilized blood differs from that of CD34− and CD34+ cells from bone marrow

scientific article published on 01 September 2000

Male germ-line cells are at risk following direct-injection retroviral-mediated gene transfer in utero

scientific article

Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery

scientific article

Mesenchymal stem cells contribute to endogenous FVIII:c production

scientific article published on May 2013

Mesenchymal stem cells engineered to inhibit complement-mediated damage

scientific article

Mesenchymal stem cells in myeloproliferative disorders - focus on primary myelofibrosis

scientific article published on 02 October 2018

Microgravity Impairs DNA Damage Repair in Human Hematopoietic Stem/Progenitor Cells and Inhibits Their Differentiation into Dendritic Cells

scientific article published on 16 July 2018

Modelling of ex vivo expansion/maintenance of hematopoietic stem cells

scientific article published on 28 January 2003

Modulation of human mesenchymal stem cell immunogenicity through forced expression of human cytomegalovirus us proteins

scientific article

New models to investigate mechanisms of disease genesis from primitive BCR-ABL(+) hematopoietic cells

scientific article published on May 2003

Pancytopenia in allogeneic marrow transplant recipients: role of cytomegalovirus

scientific article published on 01 June 1994

Perivascular stromal cells as a potential reservoir of human cytomegalovirus

scientific article

Persistent circulating human insulin in sheep transplanted in utero with human mesenchymal stem cells

scientific article

Phenotypic correction of hemophilia A in sheep by postnatal intraperitoneal transplantation of FVIII-expressing MSC.

scientific article published on 8 September 2011

Plasmodium-falciparum-infected erythrocytes adhere to immortalized human bone marrow endothelial cells

scientific article published on 01 July 1998

Plasticity of human stem cells in the fetal sheep model of human stem cell transplantation

scientific article published on January 2004

Purification of interstitial cells of Cajal by fluorescence-activated cell sorting.

scientific article

Reduced stem cell factor links smooth myopathy and loss of interstitial cells of cajal in murine diabetic gastroparesis.

scientific article

Regenerative medicine: prospects for the treatment of inflammatory bowel disease.

scientific article published on September 2013

Retention and multilineage expression of human hematopoietic stem cells in human-sheep chimeras

scientific article published on March 1995

Reversible expression of CD34 by adult human bone marrow long-term engrafting hematopoietic stem cells

scientific article published on 01 May 2003

Sheep CD34+ amniotic fluid cells have hematopoietic potential and engraft after autologous in utero transplantation

scientific article published in January 2015

Soluble Fas affects erythropoiesis in vitro and acts as a potential predictor of erythropoiesis-stimulating agent therapy in patients with chronic kidney disease

scientific article published on 31 January 2020

Stem cell gene manipulation and delivery as systemic therapeutics ⬇️

scientific article published on September 30, 2010

Sustained, retransplantable, multilineage engraftment of highly purified adult human bone marrow stem cells in vivo

scientific article published on 01 December 1996

Systematic delineation of optimal cytokine concentrations to expand hematopoietic stem/progenitor cells in co-culture with mesenchymal stem cells

scientific article published on 27 April 2010

Targeting Mesenchymal Stromal Cells/Pericytes (MSCs) With Pulsed Electromagnetic Field (PEMF) Has the Potential to Treat Rheumatoid Arthritis

scholarly article by Christina L. Ross et al published 4 March 2019 in Frontiers in Immunology

Temporal definition of haematopoietic stem cell niches in a large animal model of in utero stem cell transplantation

scientific article

The correlation between the adsorption of adhesive proteins and cell behaviour on hydroxyl-methyl mixed self-assembled monolayers

scientific article published on 25 October 2008

The effect of low-frequency electromagnetic field on human bone marrow stem/progenitor cell differentiation.

scientific article

The effect of short-chain fatty acids on the susceptibility of human umbilical vein endothelial cells to human cytomegalovirus infection.

scientific article

The fetal sheep: a unique model system for assessing the full differentiative potential of human stem cells

scientific article published in June 2004

The hematopoietic system in the context of regenerative medicine

scientific article published on 25 August 2015

The human-sheep chimeras as a model for human stem cell mobilization and evaluation of hematopoietic grafts' potential

scientific article

The human/sheep xenograft model: a large animal model of human hematopoiesis

scientific article published on April 1996

The monoclonal antibody W7C5 defines a novel surface antigen on hematopoietic stem cells

scientific article published on 01 June 2001

The role of sheep stroma in human haemopoiesis in the human/sheep chimaeras

scientific article published on 01 June 1996

The sheep model of in utero gene therapy

scientific article published on January 2004

The time course of engraftment of human mesenchymal stem cells in fetal heart demonstrates that Purkinje fiber aggregates derive from a single cell and not multi-cell homing

scientific article published on 01 July 2006

Therapeutic Mesenchymal Stromal Cells for Immunotherapy and for Gene and Drug Delivery

scientific article published on 22 January 2020

Transduction of long-term-engrafting human hematopoietic stem cells by retroviral vectors

scientific article published in May 2002

Transplantation of hematopoietic stem cells in utero

scientific article published on January 1997

Treatment of Hemophilia A in Utero and Postnatally using Sheep as a Model for Cell and Gene Delivery

scientific article

Treatment of X-linked severe combined immunodeficiency by in utero transplantation of paternal bone marrow

scientific article published on 01 December 1996

Umbilical cord blood cells capable of engrafting in primary, secondary, and tertiary xenogeneic hosts are preserved after ex vivo culture in a noncontact system

article

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