Search filters

List of works by Hubertus Haas

18th European Symposium on Radiopharmacy and Radiopharmaceuticals

article

4?-Phosphopantetheinyl transferase-encoding npgA is essential for siderophore biosynthesis in Aspergillus nidulans ⬇️

scientific article published on September 24, 2003

68Ga-siderophores for PET imaging of invasive pulmonary aspergillosis: proof of principle

scientific article

68Ga-triacetylfusarinine C and 68Ga-ferrioxamine E for Aspergillus infection imaging: uptake specificity in various microorganisms

scientific article published on February 2014

A circadian oscillator in Aspergillus spp. regulates daily development and gene expression

scientific article

A novel motif in fungal class 1 histone deacetylases is essential for growth and development of Aspergillus

scientific article

Active internalization of the Penicillium chrysogenum antifungal protein PAF in sensitive aspergilli.

scientific article published on November 2003

Additional oxidative stress reroutes the global response of Aspergillus fumigatus to iron depletion.

scientific article published on 10 May 2018

Ambient Availability of Amino Acids, Proteins, and Iron Impacts Copper Resistance of <i>Aspergillus fumigatus</i>

scientific article published on 22 April 2022

AmcA-a putative mitochondrial ornithine transporter supporting fungal siderophore biosynthesis

scientific article

An endogenous promoter for conditional gene expression in Acremonium chrysogenum: the xylan and xylose inducible promoter xyl1(P.).

scientific article published on 15 November 2013

An iron-mimicking, Trojan horse-entering fungi--has the time come for molecular imaging of fungal infections?

scientific article published on 29 January 2015

Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia

scientific article

Arginine Auxotrophy Affects Siderophore Biosynthesis and Attenuates Virulence of Aspergillus fumigatus

scientific article published on 15 April 2020

Aspergillus fumigatus SidJ mediates intracellular siderophore hydrolysis

scientific article published on 13 September 2013

Bimodular peptide synthetase SidE produces fumarylalanine in the human pathogen Aspergillus fumigatus

scientific article published on 23 August 2013

Biosynthesis and uptake of siderophores is controlled by the PacC-mediated ambient-pH Regulatory system in Aspergillus nidulans

scientific article published on April 2004

Biotrophy-specific downregulation of siderophore biosynthesis in Colletotrichum graminicola is required for modulation of immune responses of maize

scientific article

Bronchoalveolar lavage triacetylfusarinine C (TAFC) determination for diagnosis of invasive pulmonary aspergillosis in patients with hematological malignancies

scientific article published on 30 May 2017

ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence

scientific article (publication date: November 2014)

Characterization of the Link between Ornithine, Arginine, Polyamine and Siderophore Metabolism in Aspergillus fumigatus.

scientific article

Comparative proteomics of a tor inducible Aspergillus fumigatus mutant reveals involvement of the Tor kinase in iron regulation.

scientific article published on 26 May 2015

Comparison of 68Ga-labeled RGD mono- and multimers based on a clickable siderophore-based scaffold

scientific article published on 25 October 2019

Comparison of Ga-68-Labeled Fusarinine C-Based Multivalent RGD Conjugates and [(68)Ga]NODAGA-RGD-In Vivo Imaging Studies in Human Xenograft Tumors

scientific article published on 23 February 2016

Coordination of hypoxia adaptation and iron homeostasis in human pathogenic fungi ⬇️

scientific article published on November 6, 2012

Correction: Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex

scientific article published on 14 December 2016

Correction: Targeting Iron Acquisition Blocks Infection with the Fungal Pathogens and

Correction: The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis. ⬇️

scientific article published on 18 June 2015

Deciphering the combinatorial DNA-binding code of the CCAAT-binding complex and the iron-regulatory basic region leucine zipper (bZIP) transcription factor HapX.

scientific article published on 14 January 2015

Developing Targeted Hybrid Imaging Probes by Chelator Scaffolding

scientific article

Development-dependent scavenging of nucleic acids in the filamentous fungus Aspergillus fumigatus.

scientific article published on 28 April 2009

Differentially regulated high-affinity iron assimilation systems support growth of the various cell types in the dimorphic pathogen Talaromyces marneffei.

scientific article

Distinct roles for intra- and extracellular siderophores during Aspergillus fumigatus infection

scientific article

Enhanced labile plasma iron in hematopoietic stem cell transplanted patients promotes Aspergillus outgrowth

scientific article published on 01 June 2019

Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus

scientific article published on 17 October 2016

Erratum: Corrigendum: Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

scientific article published in Nature

EstB-mediated hydrolysis of the siderophore triacetylfusarinine C optimizes iron uptake of Aspergillus fumigatus

scientific article published on 22 June 2007

Exploiting the Concept of Multivalency with 68Ga- and 89Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression.

scientific article published on 10 April 2018

Exploring the concordance of Aspergillus fumigatus pathogenicity in mice and Toll-deficient flies.

scientific article published in May 2010

Factor H Binding Molecule Hgt1p - A Low Glucose-Induced Transmembrane Protein Is Trafficked to the Cell Wall and Impairs Phagocytosis and Killing by Human Neutrophils

scientific article published in 2018

Ferricrocin, a siderophore involved in intra- and transcellular iron distribution in Aspergillus fumigatus.

scientific article published on 17 April 2009

Functional and physical interaction of blue- and red-light sensors in Aspergillus nidulans

scientific article published in February 2008

Fungal iron homeostasis with a focus on Aspergillus fumigatus

scientific article published on 09 October 2020

Fungal siderophore biosynthesis is partially localized in peroxisomes.

scientific article published on 26 April 2013

Fungal siderophore metabolism with a focus on <i>Aspergillus fumigatus</i>: impact on biotic interactions and potential translational applications

scientific article published in 2023

Fusarinine C, a novel siderophore-based bifunctional chelator for radiolabeling with Gallium-68.

scientific article published on 15 April 2015

Genome mining and functional genomics for siderophore production in Aspergillus niger ⬇️

scientific article published on 25 July 2014

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

scientific article

HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus

scientific article

HapX-mediated iron homeostasis is essential for rhizosphere competence and virulence of the soilborne pathogen Fusarium oxysporum

scientific article published on 11 September 2012

HdaA, a major class 2 histone deacetylase of Aspergillus nidulans, affects growth under conditions of oxidative stress.

scientific article

Histidine biosynthesis plays a crucial role in metal homeostasis and virulence of Aspergillus fumigatus.

scientific article published on 6 February 2016

Histone deacetylases in fungi: novel members, new facts

scientific article

Human tear lipocalin exhibits antimicrobial activity by scavenging microbial siderophores

scientific article

Hybrid Imaging Agents for Pretargeting Applications Based on Fusarinine C-Proof of Concept

scientific article published on 01 May 2020

Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores

scientific article published on 22 January 2020

Hydroxamate production as a high affinity iron acquisition mechanism in Paracoccidioides spp.

scientific article

Identification and characterization of haemofungin, a novel antifungal compound that inhibits the final step of haem biosynthesis

scientific article published on 7 January 2016

Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography

scientific article published in Scientific Reports

In Vitro and In Vivo Comparison of Selected Ga-68 and Zr-89 Labelled Siderophores.

scientific article published on 30 September 2015

In vitro and in vivo evaluation of selected 68Ga-siderophores for infection imaging

scientific article published on 14 December 2011

Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by iron

scientific article published on 14 June 2007

Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases

scientific article published on 27 August 2018

Iron competition in fungus-plant interactions: the battle takes place in the rhizosphere

scientific article

Iron homeostasis—Achilles’ heel of Aspergillus fumigatus? ⬇️

scientific article published on July 1, 2011

Iron-sensing is governed by mitochondrial, not by cytosolic iron-sulfur cluster biogenesis in Aspergillus fumigatus

scientific article published in November 2018

Live-cell imaging with Aspergillus fumigatus-specific fluorescent siderophore conjugates

scientific article published on 23 September 2020

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.

scientific article published on 14 June 2018

Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus

scientific article published on 21 November 2011

Microhemorrhage-associated tissue iron enhances the risk for Aspergillus fumigatus invasion in a mouse model of airway transplantation.

scientific article

Modifying the Siderophore Triacetylfusarinine C for Molecular Imaging of Fungal Infection

scientific article published on 01 December 2019

Multimerization results in formation of re-bindable metabolites: A proof of concept study with FSC-based minigastrin imaging probes targeting CCK2R expression

scientific article published in PLoS ONE

Multiplex Genetic Engineering Exploiting Pyrimidine Salvage Pathway-Based Endogenous Counterselectable Markers

scientific article published on 07 April 2020

Novel Bifunctional Cyclic Chelator for (89)Zr Labeling-Radiolabeling and Targeting Properties of RGD Conjugates

scientific article published on 19 May 2015

Novel intermicrobial molecular interaction: Pseudomonas aeruginosa Quinolone Signal (PQS) modulates Aspergillus fumigatus response to iron

scientific article published on 15 November 2019

Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus ⬇️

scientific article

Potential basis for amphotericin B resistance in Aspergillus terreus

scientific article published on 11 February 2008

Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging.

scientific article

Pseudomonas aeruginosa manipulates redox and iron homeostasis of its microbiota partner Aspergillus fumigatus via phenazines

scientific article published on 10 February 2015

Rapid detection of the aspergillosis biomarker triacetylfusarinine C using interference-enhanced Raman spectroscopy

scientific article published on 14 March 2020

Rational Design, Synthesis and Preliminary Evaluation of Novel Fusarinine C-Based Chelators for Radiolabeling with Zirconium-89

article

Regulation of sulphur assimilation is essential for virulence and affects iron homeostasis of the human-pathogenic mould Aspergillus fumigatus.

scientific article

Regulatory interactions for iron homeostasis in Aspergillus fumigatus inferred by a Systems Biology approach ⬇️

scientific article published on January 19, 2012

Riboflavin and pantothenic acid biosynthesis are crucial for iron homeostasis and virulence in the pathogenic mold Aspergillus fumigatus

scientific article published on 01 January 2018

SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus

scientific article

Selected ⁶⁸Ga-siderophores versus ⁶⁸Ga-colloid and ⁶⁸Ga-citrate: biodistribution and small animal imaging in mice

scientific article published on 29 October 2014

Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin

scientific article

SidL, an Aspergillus fumigatus Transacetylase Involved in Biosynthesis of the Siderophores Ferricrocin and Hydroxyferricrocin ⬇️

scientific article published on May 27, 2011

Siderophore Scaffold as Carrier for Antifungal Peptides in Therapy of <i>Aspergillus fumigatus</i> Infections

scientific article published on 15 December 2020

Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence ⬇️

scientific article

Siderophore-Based Molecular Imaging of Fungal and Bacterial Infections-Current Status and Future Perspectives

scientific article published on 29 May 2020

Siderophores for molecular imaging applications.

scientific article published on 11 October 2016

Siroheme Is Essential for Assimilation of Nitrate and Sulfate as Well as Detoxification of Nitric Oxide but Dispensable for Murine Virulence of

scientific article published on 12 November 2018

Small ncRNA transcriptome analysis from Aspergillus fumigatus suggests a novel mechanism for regulation of protein synthesis

scientific article

SreA-mediated iron regulation in Aspergillus fumigatus

scientific article (publication date: October 2008)

Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex

scientific article

Structural basis of HapEP88L-linked antifungal triazole resistance in Aspergillus fumigatus

scientific article published on 28 May 2020

Sub-telomere directed gene expression during initiation of invasive aspergillosis

scientific article

Systematic Identification of Anti-Fungal Drug Targets by a Metabolic Network Approach

scientific article published on 17 June 2016

Targeting iron acquisition blocks infection with the fungal pathogens Aspergillus fumigatus and Fusarium oxysporum

scientific article

The CCAAT-binding complex (CBC) in Aspergillus species

scientific article published on 8 December 2016

The CCAAT-binding complex coordinates the oxidative stress response in eukaryotes

scientific article

The Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess

scientific article

The Lysine Deacetylase RpdA Is Essential for Virulence in Aspergillus fumigatus

scientific article published on 04 December 2019

The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus

scientific article published on 30 August 2011

The Siderophore Transporter Sit1 Determines Susceptibility to the Antifungal VL-2397

scientific article published on 23 September 2019

The Zn2Cys6-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus

scientific article published on 26 October 2018

The crucial role of the Aspergillus fumigatus siderophore system in interaction with alveolar macrophages

scientific article published on 24 July 2010

The cytochrome b5 CybE is regulated by iron availability and is crucial for azole resistance in A. fumigatus.

scientific article published on 26 October 2017

The first promoter for conditional gene expression in Acremonium chrysogenum: iron starvation-inducible mir1(P).

scientific article published on 23 October 2012

The fungal CCAAT-binding complex and HapX display highly variable but evolutionary conserved synergetic promoter-specific DNA recognition

scientific article published on 22 February 2020

The interplay between iron and zinc metabolism in Aspergillus fumigatus.

scientific article published on 19 May 2009

The interplay between vacuolar and siderophore-mediated iron storage in Aspergillus fumigatus ⬇️

scientific article published on November 14, 2012

The intracellular siderophore ferricrocin is involved in iron storage, oxidative-stress resistance, germination, and sexual development in Aspergillus nidulans

scientific article published on October 2006

The leucine biosynthetic pathway is crucial for adaptation to iron starvation and virulence in Aspergillus fumigatus

scientific article published on 01 December 2019

The metalloreductase FreB is involved in adaptation of Aspergillus fumigatus to iron starvation.

scientific article

The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus

scientific article published on 16 September 2019

The novel globin protein fungoglobin is involved in low oxygen adaptation of Aspergillus fumigatus

scientific article published on 7 July 2014

The pH-responsive PacC transcription factor of Aspergillus fumigatus governs epithelial entry and tissue invasion during pulmonary aspergillosis ⬇️

scientific article (publication date: October 2014)

The role of coproporphyrinogen III oxidase and ferrochelatase genes in heme biosynthesis and regulation in Aspergillus niger

scientific article published on 11 October 2013

The siderophore system is essential for viability of Aspergillus nidulans: functional analysis of two genes encoding l-ornithine N 5-monooxygenase (sidA) and a non-ribosomal peptide synthetase (sidC).

scientific article

The small molecular mass antifungal protein of Penicillium chrysogenum--a mechanism of action oriented review

scientific article published on 21 July 2011

Transcriptional response of <i>Aspergillus fumigatus</i> to copper and the role of the Cu chaperones

scientific article published on 01 December 2021

Triacetylfusarinine C: A urine biomarker for diagnosis of invasive aspergillosis

scientific article published on 26 September 2018

[(68)Ga]FSC-(RGD)3 a trimeric RGD peptide for imaging αvβ3 integrin expression based on a novel siderophore derived chelating scaffold-synthesis and evaluation

scientific article

β-1,3-glucan-lacking Aspergillus fumigatus mediates an efficient antifungal immune response by activating complement and dendritic cells

scientific article published on 29 October 2018

Paulina is supported by:

About Paulina

Help