List of works - Raymond A Sobel

A Model of Coccidioidal Meningoencephalitis and Cerebrospinal Vasculitis in the Rabbit ⬇️

scientific article published on October 1, 1998

A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease

scientific article

A transgenic model of central nervous system autoimmunity mediated by CD4+ and CD8+ T and B cells

scientific article published on 25 January 2012

Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo

scientific article

Altered peptide ligand modulation of experimental allergic encephalomyelitis: immune responses within the CNS ⬇️

scientific article published on January 1, 1998

Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation

scientific article

Anti-Myelin Proteolipid Protein Peptide Monoclonal Antibodies Recognize Cell Surface Proteins on Developing Neurons and Inhibit Their Differentiation

scientific article published on 01 September 2019

Anti-viral T-cell immunity+anti-CNS autoantibody=a model for human acute disseminated encephalomyelitis or multiple sclerosis relapse?

scientific article published on February 2007

Apparent expression of varicella-zoster virus proteins in latency resulting from reactivity of murine and rabbit antibodies with human blood group a determinants in sensory neurons

scientific article published on 19 October 2011

Aspergillus fumigatus invasion increases with progressive airway ischemia ⬇️

scientific article (publication date: 2013)

B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity.

scientific article published on 28 March 2015

Benign spinal nerve sheath tumors: their occurrence sporadically and in neurofibromatosis types 1 and 2 ⬇️

scientific article published on 01 February 1991

Buerger's disease involving the celiac artery

scientific article published on January 1, 1979

Chaperone Activity of Small Heat Shock Proteins Underlies Therapeutic Efficacy in Experimental Autoimmune Encephalomyelitis ⬇️

scientific article published on September 6, 2012

Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease

scientific article

Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis ⬇️

scientific article published on October 15, 1993

Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice

scientific article

Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.

scientific article

Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation

scientific article

Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity.

scientific article

Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function.

scientific article published on 12 March 2018

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

scientific article

Effects of phorbol myristate acetate (PMA) on functions of macrophages and microglia in vitro

scientific article published on 01 March 1998

Endothelial Cell Integrin Laminin Receptor Expression in Multiple Sclerosis Lesions ⬇️

scientific article published on August 1, 1998

Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice.

scientific article published on 11 December 2017

Expansion by self antigen is necessary for the induction of experimental autoimmune encephalomyelitis by T cells primed with a cross-reactive environmental antigen ⬇️

scientific article published on 01 October 1998

Experimental allergic encephalomyelitis mediated by cloned T cells specific for a synthetic peptide of myelin proteolipid protein. Fine specificity and T cell receptor V beta usage ⬇️

scientific article published on June 15, 1992

Expression of varicella-zoster virus immediate-early regulatory protein IE63 in neurons of latently infected human sensory ganglia

scientific article

Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis ⬇️

scientific article published on October 1, 1997

Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity.

scientific article published on 2 March 2018

Gene therapy and hypothermia for stroke treatment.

scientific article

Growth of human acoustic neuromas, neurofibromas and schwannomas in the subrenal capsule and sciatic nerve of the nude mouse

scientific article published on 01 October 1992

Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation

scientific article published on 25 January 2007

IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice ⬇️

scientific article published on October 1, 1998

IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

scientific article published on 24 July 2019

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

scientific journal article

Identification and characterization of a second encephalitogenic determinant of myelin proteolipid protein (residues 178-191) for SJL mice ⬇️

article by J M Greer et al published 1 August 1992 in Journal of Immunology

Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE.

scientific article

Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity

scientific article

Induction and molecular signature of pathogenic TH17 cells

scientific article

Inhibition of growth and angiogenesis of human neurofibrosarcoma by heparin and hydrocortisone ⬇️

scientific article published on 01 September 1990

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

scientific article

Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity

scientific article

Microhemorrhage-associated tissue iron enhances the risk for Aspergillus fumigatus invasion in a mouse model of airway transplantation.

scientific article

Mild hypothermia increases Bcl-2 protein expression following global cerebral ischemia ⬇️

scientific article published on November 1, 2001

Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination.

scientific article

Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice

scientific article

Myelin proteolipid protein: minimum sequence requirements for active induction of autoimmune encephalomyelitis in SWR/J and SJL/J mice

scientific article published on July 1, 1992

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

scientific article

Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity

scientific article

Pre-inflammatory expression of fibronectin (Fn) and Ia in acute experimental allergic encephalomyelitis (EAE): modulation of endothelial cells (EC) in the immune response detected by quantitative immunoperoxidase studies using monoclonal antibodies

scientific article published on 01 January 1984

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.

scientific article

Rubinstein-Taybi syndrome andnasopharyngeal rhabdomyosarcoma ⬇️

scientific article published on 01 December 1981

SJL mice infected with Acanthamoeba castellanii develop central nervous system autoimmunity through the generation of cross-reactive T cells for myelin antigens

scientific article (publication date: 2014)

Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin antigens: IV. Suppression of chronic relapsing disease in the lewis rat and strain 13 guinea pig ⬇️

scientific article published on June 1, 1991

Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein VI. Suppression of adoptively transferred disease and differential effects of oral vs. intravenous tolerization ⬇️

scientific article published on 01 July 1993

T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity

scientific article published on 09 November 2020

T cell responses to myelin basic protein in experimental autoimmune encephalomyelitis-resistant BALB/c mice ⬇️

scientific article published on June 1, 1993

TIM-4 expressed on APCs induces T cell expansion and survival

scientific article

Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes

scientific article

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

scientific article

Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation

scientific article

The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease ⬇️

scientific article published on November 23, 2001

The immunopathology of acute experimental allergic encephalomyelitis induced with myelin proteolipid protein. T cell receptors in inflammatory lesions ⬇️

scientific article published on August 15, 1992

The immunopathology of experimental allergic encephalomyelitis. I. Quantitative analysis of inflammatory cells in situ ⬇️

scientific article published on May 1, 1984

Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation

scientific article

Tim-2 regulates T helper type 2 responses and autoimmunity

scientific article published on 25 July 2005

Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells.

scientific article

Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis

scientific article published on 17 August 2011

Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE).

scientific article

List of works by Raymond A Sobel

A Model of Coccidioidal Meningoencephalitis and Cerebrospinal Vasculitis in the Rabbit ⬇️

A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease

A transgenic model of central nervous system autoimmunity mediated by CD4+ and CD8+ T and B cells

Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo

Altered peptide ligand modulation of experimental allergic encephalomyelitis: immune responses within the CNS ⬇️

Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation

Anti-Myelin Proteolipid Protein Peptide Monoclonal Antibodies Recognize Cell Surface Proteins on Developing Neurons and Inhibit Their Differentiation

Anti-viral T-cell immunity+anti-CNS autoantibody=a model for human acute disseminated encephalomyelitis or multiple sclerosis relapse?

Apparent expression of varicella-zoster virus proteins in latency resulting from reactivity of murine and rabbit antibodies with human blood group a determinants in sensory neurons

Aspergillus fumigatus invasion increases with progressive airway ischemia ⬇️

B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity.

Benign spinal nerve sheath tumors: their occurrence sporadically and in neurofibromatosis types 1 and 2 ⬇️

Buerger's disease involving the celiac artery

Chaperone Activity of Small Heat Shock Proteins Underlies Therapeutic Efficacy in Experimental Autoimmune Encephalomyelitis ⬇️

Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease

Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis ⬇️

Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice

Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.

Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation

Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity.

Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function.

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

Effects of phorbol myristate acetate (PMA) on functions of macrophages and microglia in vitro

Endothelial Cell Integrin Laminin Receptor Expression in Multiple Sclerosis Lesions ⬇️

Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice.

Expansion by self antigen is necessary for the induction of experimental autoimmune encephalomyelitis by T cells primed with a cross-reactive environmental antigen ⬇️

Experimental allergic encephalomyelitis mediated by cloned T cells specific for a synthetic peptide of myelin proteolipid protein. Fine specificity and T cell receptor V beta usage ⬇️

Expression of varicella-zoster virus immediate-early regulatory protein IE63 in neurons of latently infected human sensory ganglia

Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis ⬇️

Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity.

Gene therapy and hypothermia for stroke treatment.

Growth of human acoustic neuromas, neurofibromas and schwannomas in the subrenal capsule and sciatic nerve of the nude mouse

Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation

IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice ⬇️

IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

Identification and characterization of a second encephalitogenic determinant of myelin proteolipid protein (residues 178-191) for SJL mice ⬇️

Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE.

Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity

Induction and molecular signature of pathogenic TH17 cells

Inhibition of growth and angiogenesis of human neurofibrosarcoma by heparin and hydrocortisone ⬇️

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity

Microhemorrhage-associated tissue iron enhances the risk for Aspergillus fumigatus invasion in a mouse model of airway transplantation.

Mild hypothermia increases Bcl-2 protein expression following global cerebral ischemia ⬇️

Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination.

Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice

Myelin proteolipid protein: minimum sequence requirements for active induction of autoimmune encephalomyelitis in SWR/J and SJL/J mice

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity

Pre-inflammatory expression of fibronectin (Fn) and Ia in acute experimental allergic encephalomyelitis (EAE): modulation of endothelial cells (EC) in the immune response detected by quantitative immunoperoxidase studies using monoclonal antibodies

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.

Rubinstein-Taybi syndrome andnasopharyngeal rhabdomyosarcoma ⬇️

SJL mice infected with Acanthamoeba castellanii develop central nervous system autoimmunity through the generation of cross-reactive T cells for myelin antigens

Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin antigens: IV. Suppression of chronic relapsing disease in the lewis rat and strain 13 guinea pig ⬇️

Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein VI. Suppression of adoptively transferred disease and differential effects of oral vs. intravenous tolerization ⬇️

T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity

T cell responses to myelin basic protein in experimental autoimmune encephalomyelitis-resistant BALB/c mice ⬇️

TIM-4 expressed on APCs induces T cell expansion and survival

Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation

The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease ⬇️

The immunopathology of acute experimental allergic encephalomyelitis induced with myelin proteolipid protein. T cell receptors in inflammatory lesions ⬇️

The immunopathology of experimental allergic encephalomyelitis. I. Quantitative analysis of inflammatory cells in situ ⬇️

Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation

Tim-2 regulates T helper type 2 responses and autoimmunity

Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells.

Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis

Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE).