List of works by Ulf Dittmer

Absence of measles virus genome and transcripts in Hodgkin-Reed/Sternberg cells of a cohort of Hodgkin lymphoma patients

scientific article published on July 2007

Activated CD8+ T cells induce expansion of Vβ5+ regulatory T cells via TNFR2 signaling.

scientific article

Activated regulatory T cells suppress effector NK cell responses by an IL-2-mediated mechanism during an acute retroviral infection

scientific article published on 30 July 2015

Advantages of Foxp3(+) regulatory T cell depletion using DEREG mice.

scientific article

Anti-retroviral effects of type I IFN subtypes in vivo

scientific journal article

Antibody-based immunotherapy of aciclovir resistant ocular herpes simplex virus infections

scientific article published on 3 October 2017

BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection

scientific article published on 10 September 2013

CD137 Agonist Therapy Can Reprogram Regulatory T Cells into Cytotoxic CD4+ T Cells with Antitumor Activity

scientific article published on 25 November 2015

CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection

scientific article

CD4+ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8+ T cells

scientific article published on 27 March 2013

CD8+ T cells are essential for controlling acute friend retrovirus infection in C57BL/6 mice

scientific article published on May 2014

CD8+ T-cell dysfunction due to cytolytic granule deficiency in persistent Friend retrovirus infection

scientific article

CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production

scientific article

Characterization of the Treg Response in the Hepatitis B Virus Hydrodynamic Injection Mouse Model

scientific article

Chemical modifications on siRNAs avoid Toll-like-receptor-mediated activation of the hepatic immune system in vivo and in vitro

scientific article published on 24 September 2013

Circulating HIV-Specific Interleukin-21(+)CD4(+) T Cells Represent Peripheral Tfh Cells with Antigen-Dependent Helper Functions

scientific article published on 11 January 2016

Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection

scientific article

Co-immunization of mice with a retroviral DNA vaccine and GITRL-encoding plasmid augments vaccine-induced protection against retrovirus infection

scientific article published in December 2008

Codelivery of the chemokine CCL3 by an adenovirus-based vaccine improves protection from retrovirus infection.

scientific article published on 16 November 2011

Combination of DNA prime--adenovirus boost immunization with entecavir elicits sustained control of chronic hepatitis B in the woodchuck model

scientific article

Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth

scientific article

Combining regulatory T cell depletion and inhibitory receptor blockade improves reactivation of exhausted virus-specific CD8+ T cells and efficiently reduces chronic retroviral loads

scientific article

Comment on "Premature terminal exhaustion of Friend virus-specific effector CD8+ T cells by rapid induction of multiple inhibitory receptors".

scientific article published in August 2010

Complement as an endogenous adjuvant for dendritic cell-mediated induction of retrovirus-specific CTLs.

scientific article

Complement opsonization enhances friend virus infection of B cells and thereby amplifies the virus-specific CD8+ T cell response

scientific article published on 3 November 2010

Cooperativity of HIV-Specific Cytolytic CD4 T Cells and CD8 T Cells in Control of HIV Viremia

scientific article published on 13 May 2015

Correction: PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing

scientific article published on 18 December 2015

Corrigendum to "Antibody-based immunotherapy of acyclovir resistant ocular herpes simplex virus infection" [Virology 512 (2017) 194-200]

scientific article published on 02 October 2018

CpG oligodeoxynucleotides activate HIV replication in latently infected human T cells

scientific article published on 11 March 2004

CpG oligodeoxynucleotides allow for effective adoptive T-cell therapy in chronic retroviral infection

scientific article published on 01 April 2007

Cytomegalovirus reactivation in patients with refractory checkpoint inhibitor-induced colitis

scientific article published on 19 October 2017

Different antiviral effects of IFNα and IFNβ in an HBV mouse model.

scientific article published on 8 November 2016

Different antiviral effects of IFNα subtypes in a mouse model of HBV infection.

scientific article

Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection

scientific article published on 13 September 2017

Differential impact of the transcriptional repressor Gfi1 on mature CD4+ and CD8+ T lymphocyte function

scientific article

Distinct antiviral activities of IFN-α subtypes.

scientific article

Distinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse model

scientific article

Distinct roles of NK cells in viral immunity during different phases of acute Friend retrovirus infection

scientific article published on November 2013

Dose of Retroviral Infection Determines Induction of Antiviral NK Cell Responses

scientific article published on 13 September 2017

Dual activity of phosphorothioate CpG oligodeoxynucleotides on HIV: reactivation of latent provirus and inhibition of productive infection in human T cells

scientific article

Effective postexposure treatment of retrovirus-induced disease with immunostimulatory DNA containing CpG motifs

scientific article

Effective treatment of retrovirus-induced suppression of antibody responses with CpG oligodeoxynucleotides

scientific article published on 01 December 2005

Effects of type I interferons on Friend retrovirus infection

scientific article published in April 2006

Essential role for virus-neutralizing antibodies in sterilizing immunity against Friend retrovirus infection

scholarly article

Essential roles for CD8+ T cells and gamma interferon in protection of mice against retrovirus-induced immunosuppression

scientific article

Evaluation of susceptibility of HIV-1 CRF01_AE variants to neutralization by a panel of broadly neutralizing antibodies

article

Evaluation of the Friend Virus model for the development of improved adenovirus-vectored anti-retroviral vaccination strategies

scientific article published on 5 December 2007

Evaluation of the immunomodulatory and antiviral effects of the cytokine combination IFN-α and IL-7 in the lymphocytic choriomeningitis virus and Friend retrovirus mouse infection models

scientific article published on 19 September 2011

Evolution of raltegravir resistance during therapy.

scientific article published on 14 May 2009

Expanded regulatory T cells in chronically friend retrovirus-infected mice suppress immunity to a murine cytomegalovirus superinfection

scientific article published on 17 September 2014

Expression Pattern of Individual IFNA Subtypes in Chronic HIV Infection

scientific article published in December 2017

Filariae-Retrovirus Co-infection in Mice is Associated with Suppressed Virus-Specific IgG Immune Response and Higher Viral Loads

scientific article

Friend retrovirus drives cytotoxic effectors through Toll-like receptor 3

scientific article

Friend retrovirus infection induces the development of memory-like natural killer cells

article

Friend retrovirus infection of myeloid dendritic cells impairs maturation, prolongs contact to naive T cells, and favors expansion of regulatory T cells

scientific article published on 15 August 2007

Friend virus limits adaptive cellular immune responses by imprinting a maturation-resistant and T helper type 2-biased immunophenotype in dendritic cells.

scientific article published on 9 February 2018

Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection

scientific article published in March 2004

Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8+ T cell responses during acute Friend retrovirus infection

scientific article

Hepatitis B Virus-Specific CD8+ T Cells Maintain Functional Exhaustion after Antigen Reexposure in an Acute Activation Immune Environment.

scientific article

Hepatitis B virus genome replication triggers toll-like receptor 3-dependent interferon responses in the absence of hepatitis B surface antigen

scientific article published on 28 April 2016

Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells

scientific article published in April 2009

Human pDCs display sex-specific differences in type I interferon subtypes and interferon α/β receptor expression

scientific article published on 28 November 2016

IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.

scientific article published on 11 January 2013

IL-2-independent and TNF-α-dependent expansion of Vβ5+ natural regulatory T cells during retrovirus infection

scientific article published on 03 May 2013

Imaging of cytotoxic antiviral immunity while considering the 3R principle of animal research.

scientific article published on 19 February 2018

Immune control and prevention of chronic Friend retrovirus infection

scientific article published on January 2007

Immunisation strategies against prion diseases: prime-boost immunisation with a PrP DNA vaccine containing foreign helper T-cell epitopes does not prevent mouse scrapie

scientific article published on 05 April 2007

Immunodominance of adenovirus-derived CD8(+) T cell epitopes interferes with the induction of transgene-specific immunity in adenovirus-based immunization

scientific article

Impact of valency of a glycoprotein B-specific monoclonal antibody on neutralization of herpes simplex virus

scientific article

Improved vaccine protection against retrovirus infection after co-administration of adenoviral vectors encoding viral antigens and type I interferon subtypes

scientific article

Independent roles of perforin, granzymes, and Fas in the control of Friend retrovirus infection.

scientific article published in December 2004

Infection of B Cell Follicle-Resident Cells by Friend Retrovirus Occurs during Acute Infection and Is Maintained during Viral Persistence

scientific article published in 2019

Inhibition of catecholamine degradation ameliorates while chemical sympathectomy aggravates the severity of acute Friend retrovirus infection in mice

scientific article

Interference of retroviral envelope with vaccine-induced CD8+ T cell responses is relieved by co-administration of cytokine-encoding vectors

scientific article

Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo

scientific article published on 20 April 2016

Interferon α subtypes in HIV infection.

scientific article published on 13 February 2018

Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection

scientific article

Interferon-α Subtypes in an Ex Vivo Model of Acute HIV-1 Infection: Expression, Potency and Effector Mechanisms

scientific article published on 3 November 2015

Interleukin 21 augments the hepatitis B virus-specific CD8+ T-cell response in vitro in patients coinfected with HIV-1.

scientific article published in November 2012

Interleukin-encoding adenoviral vectors as genetic adjuvant for vaccination against retroviral infection

scientific article

Kinetics of CD8+ effector T cell responses and induced CD4+ regulatory T cell responses during Friend retrovirus infection

scientific article published on 01 October 2006

Low hepatitis B virus-specific T-cell response in males correlates with high regulatory T-cell numbers in murine models

scientific article published on 13 March 2017

Mechanisms of control of acute Friend virus infection by CD4+ T helper cells and their functional impairment by regulatory T cells

scientific article published on 14 October 2009

Modification of one epitope-flanking amino acid allows for the induction of friend retrovirus-specific CD8+ T cells by Adenovirus-based immunization.

scientific article published on 29 August 2012

Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response

scientific article published on 22 August 2013

NK cells improve control of friend virus infection in mice persistently infected with murine cytomegalovirus

scientific article published on 5 June 2013

Natural killer T cells contribute to the control of acute retroviral infection

scientific article published on 26 January 2017

Natural regulatory T cells and persistent viral infection

scientific article

Natural regulatory T cells inhibit production of cytotoxic molecules in CD8⁺ T cells during low-level Friend retrovirus infection

scientific article

No SEVI-mediated enhancement of rectal HIV-1 transmission of HIV-1 in two humanized mouse cohorts

scientific article published on 20 November 2015

Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus.

scientific article

Overcoming drug-resistant herpes simplex virus (HSV) infection by a humanized antibody

scientific article published on 8 April 2013

PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing

scientific article published on 20 October 2015

Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease

scientific article published on 13 October 2010

Pre-exposure prophylaxis failure with tenofovir disoproxil.

scientific article published on January 2017

Preclinical development of TLR ligands as drugs for the treatment of chronic viral infections.

scientific article published on 19 May 2012

Preinfection treatment of resistant mice with CpG oligodeoxynucleotides renders them susceptible to friend retrovirus-induced leukemia

scientific article published on October 2003

Prevention of herpes simplex virus induced stromal keratitis by a glycoprotein B-specific monoclonal antibody

scientific article

Prophylactic and therapeutic vaccination with a nanoparticle-based peptide vaccine induces efficient protective immunity during acute and chronic retroviral infection.

scientific article

Protection of mice against Friend retrovirus infection by vaccination with antigen-loaded, spleen-derived dendritic cells.

scientific article published in July 2004

Reduced Frequencies and Activation of Regulatory T Cells After the Treatment of HIV-1-Infected Individuals with the CCR5 Antagonist Maraviroc Are Associated with a Reduction in Viral Loads Rather Than a Direct Effect of the Drug on Regulatory T Cell

scientific article

Regulatory T cells suppress antiviral immune responses and increase viral loads during acute infection with a lymphotropic retrovirus

scientific article

Replication, Immunogenicity, and Protective Properties of Live-Attenuated Simian Immunodeficiency Viruses Expressing Interleukin-4 or Interferon-γ

scientific article published on 01 January 2003

Shift of HIV tropism in stem-cell transplantation with CCR5 Delta32 mutation

scientific article published in August 2014

Silencing T cells or T-cell silencing: concepts in virus-induced immunosuppression

scientific article

Suppression of acute anti-friend virus CD8+ T-cell responses by coinfection with lactate dehydrogenase-elevating virus

scientific article

Susceptibility of different hepatitis B virus isolates to interferon-alpha in a mouse model based on hydrodynamic injection

scientific article

TLR ligand induced IL-6 counter-regulates the anti-viral CD8(+) T cell response during an acute retrovirus infection

scientific article published on 21 May 2015

TLR1/2 ligand-stimulated mouse liver endothelial cells secrete IL-12 and trigger CD8+ T cell immunity in vitro

scientific article published on 13 November 2013

Targeting viral antigens to CD11c on dendritic cells induces retrovirus-specific T cell responses

scientific article

Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in mice

scientific article

Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.

scientific article published on 5 February 2016

The Cytotoxic Activity of Natural Killer Cells Is Suppressed by IL-10 Regulatory T Cells During Acute Retroviral Infection

The IL-1R/TLR signaling pathway is essential for efficient CD8(+) T-cell responses against hepatitis B virus in the hydrodynamic injection mouse model

scientific article

The PD-1/PD-L1 Pathway Affects the Expansion and Function of Cytotoxic CD8 T Cells During an Acute Retroviral Infection

The V1 region of gp120 is preferentially selected during SIV/HIV transmission and is indispensable for envelope function and virus infection

scientific article published on 19 April 2016

The expression of PD-1 ligands and their involvement in regulation of T cell functions in acute and chronic woodchuck hepatitis virus infection

scientific article

The level of friend retrovirus replication determines the cytolytic pathway of CD8+ T-cell-mediated pathogen control

scientific article published on 29 August 2007

The phenotype and activation status of regulatory T cells during Friend retrovirus infection.

scientific article published on 20 January 2014

The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell response

scientific article published on 11 August 2009

The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies

scientific article published on 6 March 2013

Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific

scientific article

Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice

scientific article published on 01 December 2007

Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points

scientific article

Treatment of infectious diseases with immunostimulatory oligodeoxynucleotides containing CpG motifs

scientific article published on October 2003

Tumor-specific CD4+ T cells develop cytotoxic activity and eliminate virus-induced tumor cells in the absence of regulatory T cells.

scientific article published on 14 August 2012

Vaccination with an adenoviral vector that encodes and displays a retroviral antigen induces improved neutralizing antibody and CD4+ T-cell responses and confers enhanced protection.

scientific article

Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replication

scientific article

Woodchuck hepatitis virus core antigen-based DNA and protein vaccines induce qualitatively different immune responses that affect T cell recall responses and antiviral effects

scientific article published on 25 November 2014

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