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List of works by Irene Georgakoudi

A reflectance spectrofluorimeter for real-time spectral diagnosis of disease

article published in 2002

ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis

scientific article published on 27 December 2013

An automated image processing method to quantify collagen fibre organization within cutaneous scar tissue

scientific article

Assessment of the role of circulating breast cancer cells in tumor formation and metastatic potential using in vivo flow cytometry ⬇️

scientific article published on April 1, 2011

Autocorrelation method for fractal analysis in nonrectangular image domains.

scientific article published in November 2013

Automated Biochemical, Morphological, and Organizational Assessment of Precancerous Changes from Endogenous Two-Photon Fluorescence Images ⬇️

scientific article published on September 9, 2011

Bioactive silk protein biomaterial systems for optical devices.

scientific article published on 28 March 2008

Bioengineered silk gene delivery system for nuclear targeting

scientific article

Bioluminescence and second harmonic generation imaging reveal dynamic changes in the inflammatory and collagen landscape in early osteoarthritis

scientific article published on 14 March 2018

Bone regeneration on macroporous aqueous-derived silk 3-D scaffolds

scientific article published in May 2007

Cell-tethered ligands modulate bone remodeling by osteoblasts and osteoclasts.

scientific article

Characterization of dysplastic tissue morphology and biochemistry in Barrett's esophagus using diffuse reflectance and light scattering spectroscopy

scientific article

Characterization of mechanical and biochemical properties of developing embryonic tendon ⬇️

scientific article published on April 16, 2013

Characterization of metabolic changes associated with the functional development of 3D engineered tissues by non-invasive, dynamic measurement of individual cell redox ratios

scientific article published on 4 May 2012

Characterization of natural, decellularized and reseeded porcine tooth bud matrices.

scientific article published on 30 April 2012

Conditional deletion of RB1 in the Tie2 lineage leads to aortic valve regurgitation

scientific article published on 5 January 2018

Confocal backscattering spectroscopy for leukemic and normal blood cell discrimination

scientific article published on 8 July 2011

Confocal backscattering‐based detection of leukemic cells in flowing blood samples ⬇️

scientific article published on June 2, 2011

Confocal light scattering spectroscopic imaging system for in situ tissue characterization

scientific article published on May 2009

Detection of coronary atherosclerotic plaques with superficial proteoglycans and foam cells using real-time intrinsic fluorescence spectroscopy ⬇️

scientific article published on November 27, 2010

Development of an in vitro model to study the impact of BMP-2 on metastasis to bone

scientific article published on 23 September 2010

Diagnostic cellular organization features extracted from autofluorescence images

scientific article

Effect of processing on silk-based biomaterials: reproducibility and biocompatibility

scientific article

Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.

scientific article published on 29 February 2016

Endogenous Two-Photon Excited Fluorescence Imaging Characterizes Neuron and Astrocyte Metabolic Responses to Manganese Toxicity

scientific article published on 21 April 2017

Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues

scientific article

Endogenous light scattering as an optical signature of circulating tumor cell clusters

scientific article published on 25 February 2016

Endogenous optical biomarkers of normal and human papillomavirus immortalized epithelial cells

scientific article

Enhanced intracellular siRNA delivery using bioreducible lipid-like nanoparticles.

scientific article

Equine model for soft-tissue regeneration

scientific article

Extracellular matrix remodeling following myocardial infarction influences the therapeutic potential of mesenchymal stem cells

scientific article

Fetal brain extracellular matrix boosts neuronal network formation in 3D bioengineered model of cortical brain tissue

scientific article published on 10 December 2015

From shadow to light: visualization of extrahepatic bile ducts using image-enhanced laparoscopy

scientific article published on 30 April 2014

From single cells to tissues: interactions between the matrix and human breast cells in real time

scientific article

Fully automated, quantitative, noninvasive assessment of collagen fiber content and organization in thick collagen gels

scientific article published on 19 May 2009

Hormonal regulation of epithelial organization in a three-dimensional breast tissue culture model.

scientific article published on 25 June 2013

Hyaluronic acid modification of RNase A and its intracellular delivery using lipid-like nanoparticles

scientific article

Imaging and measurement of cell structure and organization with submicron accuracy using light scattering spectroscopy

Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis

scientific article

Improved Fourier-based characterization of intracellular fractal features.

scientific article published on October 2012

In vivo flow cytometry: a new method for enumerating circulating cancer cells

scientific article published on August 2004

Intrinsic fluorescence and diffuse reflectance spectroscopy identify superficial foam cells in coronary plaques prone to erosion

scientific article published on 4 May 2006

Intrinsic fluorescence and redox changes associated with apoptosis of primary human epithelial cells

scientific article published in November 2006

Intrinsic fluorescence changes associated with apoptosis of human epithelial keratinocytes

scientific article published in December 2005

Intrinsic fluorescence changes associated with the conformational state of silk fibroin in biomaterial matrices.

scientific article

Intrinsic optical biomarkers associated with the invasive potential of tumor cells in engineered tissue models ⬇️

scientific article published on November 10, 2010

Intrinsic versus Laser-Induced Fluorescence Spectroscopy for Coronary Atherosclerosis: A Generational Comparison Model for Testing Diagnostic Accuracy ⬇️

scientific article published on December 1, 2012

Introduction: feature issue on optical molecular probes, imaging, and drug delivery

scientific article published on 29 January 2014

Label free monitoring of megakaryocytic development and proplatelet formation in vitro

scientific article published on 27 September 2017

Laparoscopic narrow band imaging for detection of occult cancer metastases: a randomized feasibility trial

scientific article published on 21 July 2015

Lysyl oxidase-mediated collagen crosslinks may be assessed as markers of functional properties of tendon tissue formation

scientific article published on 6 December 2013

Measuring cellular structure at submicrometer scale with light scattering spectroscopy

article by V. Backman et al published 2001 in IEEE Journal of Selected Topics in Quantum Electronics

Membrane potential depolarization causes alterations in neuron arrangement and connectivity in cocultures

scientific article

Multiexcitation fluorescence and reflectance spectroscopy as a real-time guide to biopsy in vivo

Non-destructive two-photon excited fluorescence imaging identifies early nodules in calcific aortic-valve disease

scientific article published on 06 November 2017

Non-invasive Assessments of Adipose Tissue Metabolism In Vitro

scientific article published on 23 September 2015

Non-invasive characterization of structure and morphology of silk fibroin biomaterials using non-linear microscopy

scientific article

Non-invasive monitoring of cell metabolism and lipid production in 3D engineered human adipose tissues using label-free multiphoton microscopy

scientific article published on 09 August 2013

Non-invasive optical characterization of biomaterial mineralization

scientific article published on 3 March 2008

Noninvasive assessment of mitochondrial organization in three-dimensional tissues reveals changes associated with cancer development

scientific article

Noninvasive identification of subcellular organization and nuclear morphology features associated with leukemic cells using light-scattering spectroscopy ⬇️

scientific article published on March 1, 2011

Noninvasive metabolic imaging of engineered 3D human adipose tissue in a perfusion bioreactor

scientific article

Optical characterization of the nanoscale organization of mineral deposits on silk films

scientific article

Optical metrics of the extracellular matrix predict compositional and mechanical changes after myocardial infarction

scientific article

Optical spectroscopy and imaging for the noninvasive evaluation of engineered tissues

scientific article published on December 2008

Osteoblastic differentiation and stress response of human mesenchymal stem cells exposed to alternating current electric fields

scientific article

Osteoinductive silk-silica composite biomaterials for bone regeneration

scientific article

Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells

scientific article published on March 2007

Quantitative biomarkers of stem cell differentiation based on intrinsic two-photon excited fluorescence

scientific article published in November 2007

Quantitative characterization of mineralized silk film remodeling during long-term osteoblast-osteoclast co-culture

scientific article published on 29 January 2014

Quantitative differentiation of normal and scarred tissues using second-harmonic generation microscopy

scientific article

Quantitative metabolic imaging using endogenous fluorescence to detect stem cell differentiation

scientific article published on 5 December 2013

Rapid quantification of pixel-wise fiber orientation data in micrographs.

scientific article

Rapid three-dimensional quantification of voxel-wise collagen fiber orientation.

scientific article published on 3 June 2015

Real-time detection of circulating apoptotic cells by in vivo flow cytometry

scientific article published on October 2005

Simple fabrication technique for rapid prototyping of seamless cylindrical microchannels in polymer substrates

scientific article published in April 2007

Skin regeneration with all accessory organs following ablation with irreversible electroporation

scientific article published on 14 December 2016

Skin rejuvenation with non-invasive pulsed electric fields

scientific article published on 12 May 2015

Spectroscopic detection and evaluation of morphologic and biochemical changes in early human oral carcinoma

scientific article

Spectroscopic diagnosis and imaging of invisible pre-cancer

scientific article

The combined use of fluorescence, reflectance, and light-scattering spectroscopy for evaluating dysplasia in Barrett's esophagus

scientific article published in July 2004

Topics in Biomedical Optics: introduction to the feature issue

scientific article published on 01 April 2009

Trimodal spectroscopy for the detection and characterization of cervical precancers in vivo

scientific article published in March 2002

Two-photon excited fluorescence of intrinsic fluorophores enables label-free assessment of adipose tissue function

scientific article published on 05 August 2016

Two-photon microscopy for non-invasive, quantitative monitoring of stem cell differentiation

scientific article

UV and NIR-Responsive Layer-by-Layer Films Containing 6-Bromo-7-hydroxycoumarin Photolabile Groups

scientific article published on 2 October 2017

Variability in responses observed in human white adipose tissue models

scientific article published on 6 September 2017

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