List of works - Jason R Spence

A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids

scientific article published on 11 October 2016

Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis

scientific article published on 09 September 2020

BRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis.

scientific article published on 10 January 2017

Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium.

scientific article published on 7 November 2017

Biologically inspired approaches to enhance human organoid complexity

scientific article published on 16 April 2019

Correction to: hPSC-derived organoids: models of human development and disease

scientific article published on 17 November 2020

Generation of lung organoids from human pluripotent stem cells in vitro

scientific article published on 01 February 2019

Human distal lung maps and lineage hierarchies reveal a bipotent progenitor

scientific article

Identification, isolation, and characterization of human LGR5-positive colon adenoma cells.

scientific article published on 21 February 2018

In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development.

scientific article published on 07 December 2016

Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity

scientific article published on 11 January 2021

R-SPONDIN2 mesenchymal cells form the bud tip progenitor niche during human lung development

scientific article published in 2022

RYK-mediated filopodial pathfinding facilitates midgut elongation

scientific article published on 29 September 2020

Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney

scientific article published on 30 August 2018

Synthetic hydrogels for human intestinal organoid generation and colonic wound repair

scientific article published on 23 October 2017

The Lumen of Human Intestinal Organoids Poses Greater Stress to Bacteria Compared to the Germ-Free Mouse Intestine: Escherichia coli Deficient in RpoS as a Colonization Probe

scientific article published in 2020

The lineage-specific transcription factor CDX2 navigates dynamic chromatin to control distinct stages of intestine development

scientific article published on 01 March 2019

Understanding Human Lung Development through In Vitro Model Systems

scientific article published on 20 April 2020

hPSC-derived organoids: models of human development and disease

scientific article published on 28 August 2020

List of works by Jason R Spence