List of works by Richard M Ransohoff

"Thinking without thinking" about natalizumab and PML.

scientific article

A Neuroprotective Effect of the Glutamate Receptor Antagonist MK801 on Long-Term Cognitive and Behavioral Outcomes Secondary to Experimental Cerebral Malaria.

scientific article published on 28 October 2016

A destructive feedback loop mediated by CXCL10 in central nervous system inflammatory disease.

scientific article

A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury.

scientific article

A meditation on medications, among other things

scientific article

A mighty mouse: building a better model of multiple sclerosis

scientific article published in September 2006

A novel method for subarachnoid hemorrhage to induce vasospasm in mice

scientific article published on July 2009

A novel model of demyelinating encephalomyelitis induced by monocytes and dendritic cells

scientific article published on 01 November 2006

A polarizing question: do M1 and M2 microglia exist?

scientific article

A protective role for ELR+ chemokines during acute viral encephalomyelitis

scientific article

A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica

scientific article

A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica.

scientific article

AAV1/2-mediated CNS gene delivery of dominant-negative CCL2 mutant suppresses gliosis, beta-amyloidosis, and learning impairment of APP/PS1 mice

scientific article published on 10 March 2009

Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells

scientific article

Acute skeletal muscle injury: CCL2 expression by both monocytes and injured muscle is required for repair

scientific article

Ageing: Blood ties

scientific article published on 31 August 2011

All (animal) models (of neurodegeneration) are wrong. Are they also useful?

scientific article published on 20 November 2018

Alterations in the oligodendrocyte lineage, myelin, and white matter in adult mice lacking the chemokine receptor CXCR2.

scientific article published in October 2006

Altered Neuroinflammation and Behavior after Traumatic Brain Injury in a Mouse Model of Alzheimer's Disease

scientific article published on 28 September 2015

Alternative and accessory pathways in the regulation of IFN-beta-mediated gene expression

scientific article

An environment-dependent transcriptional network specifies human microglia identity

scientific article published on 25 May 2017

An in vitro blood-brain barrier model combining shear stress and endothelial cell/astrocyte co-culture

scientific article

Analyses of phenotypic and functional characteristics of CX3CR1-expressing natural killer cells.

scientific article published on 14 February 2011

Analysis of leukocyte extravasation across the blood-brain barrier: conceptual and technical aspects

scientific article published on January 2004

Animal models of multiple sclerosis: the good, the bad and the bottom line

scientific article published on 26 July 2012

Antiinflammatory autoimmune cellular responses to cardiac troponin I in idiopathic dilated cardiomyopathy

scientific article

Assault on the guardian

scientific article published in Nature

Astrocyte differentiation selectively upregulates CCL2/monocyte chemoattractant protein-1 in cultured human brain-derived progenitor cells.

scientific article

Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis

scientific article

Astrocytes as antigen-presenting cells: expression of IL-12/IL-23

scientific article published on 08 August 2005

Author Correction: Single-cell transcriptomic analysis of Alzheimer's disease

scientific article published on 01 July 2019

Author Correction: TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons

scientific article published in Nature Communications

Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis.

scientific article published in January 2002

BAFF/APRIL system in pediatric OMS: relation to severity, neuroinflammation, and immunotherapy

scientific article published on 16 January 2013

BIN1 favors the spreading of Tau via extracellular vesicles

scientific article published on 01 July 2019

BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology

scientific article published on 29 July 2020

Barrier to electrical storms

journal article; published in Nature on 2009-01-07

Biomarkers for interferon response in MS: are we there yet?

scientific article published on 01 March 2008

Biomimetic post-capillary venule expansions for leukocyte adhesion studies.

scientific article published on 19 June 2018

Bone marrow transplantation confers modest benefits in mouse models of Huntington's disease

scientific article published on January 2012

CC chemokine receptor 2 is protective against noise-induced hair cell death: studies in CX3CR1(+/GFP) mice

scientific article

CC chemokine receptor 8 in the central nervous system is associated with phagocytic macrophages

scientific article published on February 2003

CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction

scientific article

CCL2 recruitment of IL-6-producing CD11b+ monocytes to the draining lymph nodes during the initiation of Th17-dependent B cell-mediated autoimmunity

scientific article published in July 2008

CCL2 transgene expression in the central nervous system directs diffuse infiltration of CD45(high)CD11b(+) monocytes and enhanced Theiler's murine encephalomyelitis virus-induced demyelinating disease ⬇️

scientific article published on December 1, 2003

CCR2 deficiency does not provide sustained improvement of muscular dystrophy in mdx5cv mice

scientific article published on 21 September 2016

CCR4 agonists CCL22 and CCL17 are elevated in pediatric OMS sera: rapid and selective down-regulation of CCL22 by ACTH or corticosteroids

scientific article published on 23 January 2013

CCR5 expression on monocytes and T cells: modulation by transmigration across the blood-brain barrier in vitro

scientific article

CCR5Delta32 polymorphism effects on CCR5 expression, patterns of immunopathology and disease course in multiple sclerosis.

scientific article

CCR7 signaling in pediatric opsoclonus-myoclonus: upregulated serum CCL21 expression is steroid-responsive

scientific article published on 10 June 2013

CD62L is not a reliable biomarker for predicting PML risk in natalizumab-treated R-MS patients

scientific article published on 30 December 2015

CD62L is not a reliable biomarker for predicting PML risk in natalizumab-treated R-MS patients. Author Response

scientific article published in August 2016

CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.

scientific article

CX3CR1 deficiency delays acute skeletal muscle injury repair by impairing macrophage functions

scientific article

CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.

scientific article

CX3CR1-dependent recruitment of mature NK cells into the central nervous system contributes to control autoimmune neuroinflammation

scientific article published on 21 June 2016

CXCL12 and CXCR4 in bone marrow physiology ⬇️

scientific article published on June 1, 2010

CXCL12-induced monocyte-endothelial interactions promote lymphocyte transmigration across an in vitro blood-brain barrier

scientific article

CXCR2 signaling protects oligodendrocyte progenitor cells from IFN-γ/CXCL10-mediated apoptosis

scientific article published on 08 June 2011

CXCR2 signaling protects oligodendrocytes and restricts demyelination in a mouse model of viral-induced demyelination

scientific article

CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis

scientific article

CXCR3 marks CD4+ memory T lymphocytes that are competent to migrate across a human brain microvascular endothelial cell layer

scientific article published on August 2004

CXCR3-dependent plasma blast migration to the central nervous system during viral encephalomyelitis

scientific article

Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion

scientific article

Capture, crawl, cross: the T cell code to breach the blood-brain barriers

scientific article published on 25 August 2012

Ccr2 deletion dissociates cavity size and tau pathology after mild traumatic brain injury

scientific article

Cell-autonomous and non-cell autonomous effects of neuronal BIN1 loss in vivo

scientific article published on 13 August 2019

Characterization of natural killer cells in paired CSF and blood samples during neuroinflammation

scientific article published on 2 September 2012

Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair

scientific article

Chemokine receptor CXCR2: physiology regulator and neuroinflammation controller?

scientific article

Chemokine receptor CXCR3: an unexpected enigma

scientific article

Chemokine receptor CXCR4 signaling modulates the growth factor‐induced cell cycle of self‐renewing and multipotent neural progenitor cells ⬇️

scientific article published on January 1, 2011

Chemokine receptors as biomarkers in multiple sclerosis

scientific article published on January 2006

Chemokines and chemokine receptors in inflammation of the CNS.

scientific article published in July 2005

Chemokines and chemokine receptors in inflammatory demyelinating neuropathies: a central role for IP-10.

scientific article published in April 2002

Chemokines and chemokine receptors in neurological disease: raise, retain, or reduce?

scientific article published on October 2007

Chemokines and chemokine receptors in the nervous system Rome, 27/28 October, 2007.

scientific article published on 29 May 2008

Chemokines and chemokine receptors in the nervous system. Rome, 24/25 October, 2009, 2nd workshop.

scientific article

Chemokines and chemokine receptors: multipurpose players in neuroinflammation.

scientific article published on January 2007

Chemokines and chemokine receptors: standing at the crossroads of immunobiology and neurobiology

scientific article

Chemokines in and out of the central nervous system: much more than chemotaxis and inflammation

scientific article published on 8 May 2008

Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment

scientific article published on 9 November 2005

Chemokines in neurological trauma models

scientific article

Chemokines, mononuclear cells and the nervous system: heaven (or hell) is in the details.

scientific article published on 28 September 2006

Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice.

scientific article published in May 2005

Clinical outcomes following surgical management of coexistent cervical stenosis and multiple sclerosis: a cohort-controlled analysis.

scientific article

Comparison of ventricular and lumbar cerebrospinal fluid T cells in non-inflammatory neurological disorder (NIND) patients

scientific article published on 22 April 2005

Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model.

scientific article

Control of microglial neurotoxicity by the fractalkine receptor

scientific journal article

Correction: Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

scientific article published on 27 April 2017

Corrigendum: multiple sclerosis-a quiet revolution

scientific article published on 24 March 2015

Cortical demyelination in PML and MS: Similarities and differences

scientific article published on 01 January 2008

Crosstalk Between Astrocytes and Microglia: An Overview

scientific article published on 16 July 2020

Cutting Edge: The Silent Chemokine Receptor D6 Is Required for Generating T Cell Responses That Mediate Experimental Autoimmune Encephalomyelitis

article

Cx3cr1-deficient microglia exhibit a premature aging transcriptome

scientific article published on 02 December 2019

D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion

scientific article published on 6 October 2011

Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages

scientific article

Defining interferon beta response status in multiple sclerosis patients.

scientific article

Depletion of Ly6G/C(+) cells ameliorates delayed cerebral vasospasm in subarachnoid hemorrhage

scientific article

Determinants of CCL5-driven mononuclear cell migration across the blood-brain barrier. Implications for therapeutically modulating neuroinflammation

scientific article published on 20 July 2006

Development, maintenance and disruption of the blood-brain barrier

scientific article

Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain

scientific article published on 24 June 2020

Differential roles of microglia and monocytes in the inflamed central nervous system

scientific article

Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.

scientific article published on January 2017

Disrupted CXCR2 Signaling in Oligodendroglia Lineage Cells Enhances Myelin Repair in a Viral Model of Multiple Sclerosis

scientific article published on 28 August 2019

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

scholarly article

Double-label nonradioactive in situ hybridization for the analysis of chemokine receptor expression in the central nervous system

scientific article published in January 2009

EAE: pitfalls outweigh virtues of screening potential treatments for multiple sclerosis

scientific article published on 02 March 2006

Editorial Research Topic "Chemokines and chemokine receptors in brain homeostasis".

scientific article

Editors' preface: microglia--a new era dawns

scientific article published in January 2013

Effect of PF-00547659 on Central Nervous System Immune Surveillance and Circulating β7+ T Cells in Crohn's Disease: Report of the TOSCA Study

scientific article published on 16 September 2017

Effects of neuromyelitis optica-IgG at the blood-brain barrier in vitro

scientific article published on 19 December 2016

Efficient derivation of microglia-like cells from human pluripotent stem cells

scientific article published on 26 September 2016

Enhanced axonal growth into a spinal cord contusion injury site in a strain of mouse (129X1/SvJ) with a diminished inflammatory response.

scientific article published in July 2004

Evidence for synaptic stripping by cortical microglia

scientific article published in March 2007

Excessive biologic response to IFNβ is associated with poor treatment response in patients with multiple sclerosis

scientific article (publication date: 2011)

Experimental autoimmune encephalomyelitis: CC chemokine receptor expression by trafficking cells

scientific article published on 01 December 2002

Expression of CCR2, CCR5, and CXCR3 by CD4+ T cells is stable during a 2-year longitudinal study but varies widely between individuals

scientific article published on 01 June 2003

Expression of CCR7 in multiple sclerosis: implications for CNS immunity

scientific article

Expression of chemokine receptors CCR1 and CCR5 reflects differential activation of mononuclear phagocytes in pattern II and pattern III multiple sclerosis lesions

scientific article

Expression of fractalkine receptor CX3CR1 on cochlear macrophages influences survival of hair cells following ototoxic injury

scientific article

Flow cytometric analysis of chemokine receptor expression on cerebrospinal fluid leukocytes

scientific article published on 01 April 2003

Fluid in the flute: Reversible hydromyelia

scientific article published on 01 September 2005

Functional Analysis of Brain-Engrafted Monocytes After Microglia Ablation in Mouse Models

scientific article published on 01 January 2019

Functional defect of peripheral neutrophils in mice with induced deletion of CXCR2

scientific article published on 24 June 2013

G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands

scientific article

GRP78 autoantibodies initiate the breakdown of the blood-brain barrier in neuromyelitis optica

scientific article published on 21 November 2017

Gathering thunder

scientific article

Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica

scientific article published in July 2017

Growth factor treatment of demyelinating disease: at last, a leap into the light.

scientific article

Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice

scientific article published on 24 September 2007

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

scientific article published on 27 September 2011

Heterogeneous, longitudinally stable molecular signatures in response to interferon-beta

scientific article

High-resolution intravital imaging reveals that blood-derived macrophages but not resident microglia facilitate secondary axonal dieback in traumatic spinal cord injury

scientific article published on 24 January 2014

How neuroinflammation contributes to neurodegeneration

scientific article

Human brain microvascular endothelial cells and umbilical vein endothelial cells differentially facilitate leukocyte recruitment and utilize chemokines for T cell migration

scientific article

Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin.

scientific article

Human cerebrospinal fluid contains CD4+ memory T cells expressing gut- or skin-specific trafficking determinants: relevance for immunotherapy.

scientific article

IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils

scientific article

IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression

scientific article

IL-17-induced Act1-mediated signaling is critical for cuprizone-induced demyelination

scientific article

Identification and Function of Fibrocytes in Skeletal Muscle Injury Repair and Muscular Dystrophy

scientific article

Identification of a unique TGF-β-dependent molecular and functional signature in microglia

scientific article

Illuminating neuromyelitis optica pathogenesis

scientific article published on 23 January 2012

Imaging correlates of leukocyte accumulation and CXCR4/CXCL12 in multiple sclerosis

scientific article

Imatinib attenuates skeletal muscle dystrophy in mdx mice

scientific article published on 16 March 2009

Immune attack: the role of inflammation in Alzheimer disease.

scientific article published on June 2015

Immune response to engineered tissues and cells: breakout session summary

Immune-cell crosstalk in multiple sclerosis

scientific article published in Nature

Immunological and clinical consequences of treating a patient with natalizumab

scientific article published on 9 September 2011

Immunological concerns with bioengineering approaches

scientific article

Immunology: In the beginning

scientific article published in November 2009

Immunology: Licensed in the lungs

scientific article published in August 2012

Immunotherapy for multiple sclerosis: the curious case of interferon beta

scientific article published on 01 October 2009

Impaired respiratory function in mdx and mdx/utrn(+/-) mice

scientific article published on February 2011

Infiltrating macrophages are broadly activated at the early stage to support acute skeletal muscle injury repair

scientific article published on 4 January 2018

Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus

scientific article published on 06 September 2016

Inflammatory cell migration into the central nervous system: a few new twists on an old tale

scientific article published on April 2007

Inflammatory cell trafficking across the blood-brain barrier: chemokine regulation and in vitro models

scientific article

Inflammatory cortical demyelination in early multiple sclerosis

scientific article published on December 2011

Inflammatory progressive multifocal leukoencephalopathy in human immunodeficiency virus-negative patients

scientific article published in July 2007

Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell-cell communication by chemokines

scientific article

Informing and inspiring

scientific article

Inhibitor of kappaB kinase is required to activate a subset of interferon gamma-stimulated genes.

scientific article

Innate immunity in the central nervous system

scientific article

Interferon signaling is dependent on specific tyrosines located within the intracellular domain of IFNAR2c. Expression of IFNAR2c tyrosine mutants in U5A cells

scientific article

Interferon-beta 1a does not reduce expression of CCR5 and CXCR3 on circulating T cells

scientific article published on 01 August 2003

Interferon-gamma-inducible protein (IP)-10 mRNA stabilized by RNA-binding proteins in monocytes treated with S100b

scientific article published on 24 August 2006

Interferons at age 50: past, current and future impact on biomedicine

scientific article

Interleukin-6 protects anterior horn neurons from lethal virus-induced injury.

scientific article published in January 2003

Is microglial apoptosis an early pathogenic change in cerebral X-linked adrenoleukodystrophy?

scientific article published in June 2008

Isolation and Preparation of Cells from Focal Remyelinating Central Nervous System Lesions for RNA Sequencing

scientific article published on 01 January 2019

Isolation of murine microglial cells for RNA analysis or flow cytometry

scientific article

Key role of CXCL13/CXCR5 axis for cerebrospinal fluid B cell recruitment in pediatric OMS.

scientific article published on 20 January 2012

Laquinimod attenuates inflammation by modulating macrophage functions in traumatic brain injury mouse model

scientific article published on 30 January 2018

Leukemia inhibitory factor deficiency modulates the immune response and limits autoimmune demyelination: a new role for neurotrophic cytokines in neuroinflammation

scientific article published on February 2008

Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis

scientific article

Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis.

scientific article

Loss of tau rescues inflammation-mediated neurodegeneration

scientific article published on 3 June 2015

Lysophosphatidylcholine regulates human microvascular endothelial cell expression of chemokines

scientific article published in November 2003

MCP-1 and CCR2 contribute to non-lymphocyte-mediated brain disease induced by Fr98 polytropic retrovirus infection in mice: role for astrocytes in retroviral neuropathogenesis

scientific article

ME-15INTERACTION BETWEEN CANCER STEM CELLS AND MYELOID DERIVED SUPPRESSOR CELLS DRIVES IMMUNOSUPPRESSION AND GLIOBLASTOMA GROWTH.

scientific article

MMP9 deficiency does not decrease blood-brain barrier disruption, but increases astrocyte MMP3 expression during viral encephalomyelitis.

scientific article

Macrophage migration inhibitory factor, the Zelig of cytokines, is a chaperone for SOD1 in non-neuronal cells

scientific article published on 01 April 2015

Macrophages recruited via CCR2 produce insulin‐like growth factor‐1 to repair acute skeletal muscle injury ⬇️

scientific article published on October 1, 2010

Major differences in the responses of primary human leukocyte subsets to IFN-beta.

scientific article published on 18 October 2010

Meet the new team!

scientific article

Memory CD4+ T-cell-mediated protection from lethal coronavirus encephalomyelitis.

scientific article published on 08 October 2008

Microglia and monocytes: 'tis plain the twain meet in the brain

scientific article published on 26 August 2011

Microglia in Health and Disease.

scientific article published on 9 September 2015

Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner

scientific article

Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy.

scientific article published on 20 February 2018

Microglial Physiology and Pathophysiology: Insights from Genome-wide Transcriptional Profiling

scientific article published on March 2016

Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events

scientific article published on 17 October 2013

Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells

scientific article

Microgliosis: the questions shape the answers

scientific article published on 01 December 2007

Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons

scientific article

Modulating CCR2 and CCL2 at the blood-brain barrier: relevance for multiple sclerosis pathogenesis

scientific article published on 17 October 2005

Modulating neurotoxicity through CX3CL1/CX3CR1 signaling

scientific article

Monocyte recruitment and myelin removal are delayed following spinal cord injury in mice with CCR2 chemokine receptor deletion

scientific article

Monocytes regulate T cell migration through the glia limitans during acute viral encephalitis

scientific article

Mononuclear phagocytes migrate into the murine cochlea after acoustic trauma

scientific article published in August 2005

Multiple roles of chemokine CXCL12 in the central nervous system: a migration from immunology to neurobiology

scientific article published on 26 November 2007

Multiple sclerosis normal-appearing white matter: pathology-imaging correlations

scientific article published on November 2011

Multiple sclerosis-a quiet revolution

scientific article

Multiple sclerosis: a study of CXCL10 and CXCR3 co-localization in the inflamed central nervous system

scientific article published on 01 June 2002

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases

scientific article

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases

Myelin repair is accelerated by inactivating CXCR2 on nonhematopoietic cells

scientific article

Natalizumab and PML

scientific article published on 01 October 2005

Natalizumab for multiple sclerosis

scientific article published on June 2007

Natalizumab, multiple sclerosis, and primary central nervous system lymphoma: enigma, wrapped in mystery, enclosed in conundrum

scientific article published on 01 September 2009

Natural killer cells modulate motor neuron-immune cell cross talk in models of Amyotrophic Lateral Sclerosis

scientific article published on 14 April 2020

Neuroimmunotherapeutics comes of age

scientific article published on 01 October 2007

Neuroinflammation in Alzheimer's disease

scientific article (publication date: April 2015)

Neuroinflammation: Surprises from the sanitary engineers

scientific article published on 6 April 2016

Neuroinflammation: Ways in Which the Immune System Affects the Brain

scientific article

Neuroscience. How many cell types does it take to wire a brain?

scientific article published in September 2011

Neutrophil depletion after subarachnoid hemorrhage improves memory via NMDA receptors

scientific article

New directions in MS therapeutics: vehicles of hope

scientific article

Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation

scientific article

Novel interferon-beta-induced gene expression in peripheral blood cells.

scientific article published on 20 August 2007

Novel interferon-β-induced gene expression in peripheral blood cells

Nuclear receptors license phagocytosis by trem2+ myeloid cells in mouse models of Alzheimer's disease.

scientific article published on April 2015

Ontogeny and functions of central nervous system macrophages.

scientific article

Opposing effects of membrane-anchored CX3CL1 on amyloid and tau pathologies via the p38 MAPK pathway

scientific article

Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition

scientific article

PDGF synergistically enhances IFN-gamma-induced expression of CXCL10 in blood-derived macrophages: implications for HIV dementia

scientific article published on 01 September 2007

PML risk and natalizumab: more questions than answers

scientific article published on 29 January 2010

Perspective: Let the sunshine in!

journal article; published in Nature on 2012-04-11

Pertussis toxin-induced reversible encephalopathy dependent on monocyte chemoattractant protein-1 overexpression in mice.

scientific article published in December 2002

Physiology. Good barriers make good neighbors

scientific article published on 2 October 2014

Polymorphic regulation of mitochondrial fission and fusion modifies phenotypes of microglia in neuroinflammation

scientific article

Progressive multifocal leukoencephalopathy in rheumatic diseases: evolving clinical and pathologic patterns of disease

scientific article

Quantifying neurologic disease using biosensor measurements in-clinic and in free-living settings in multiple sclerosis

scientific article published on 11 December 2019

REMOVED: Identification of a unique molecular and functional microglia signature in health and disease

article

Rapid remodeling of tight junctions during paracellular diapedesis in a human model of the blood-brain barrier

scientific article published on 25 July 2014

Re-establishing immunological self-tolerance in autoimmune disease

scientific article published on 06 January 2012

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

scientific article

Recovery from EAE is associated with decreased survival of encephalitogenic T cells in the CNS of B7-1/B7-2-deficient mice

scientific article published on 01 July 2003

Recurrent varicella zoster virus myelopathy

scientific article

Regulation of Tau Pathology by the Microglial Fractalkine Receptor ⬇️

scientific article published on October 6, 2010

Regulation of adaptive immunity by the fractalkine receptor during autoimmune inflammation

scientific article published on July 2013

Reply

Repopulation of cochlear macrophages in murine hematopoietic progenitor cell chimeras: the role of CX3CR1.

scientific article

Requirement of catalytically active Tyk2 and accessory signals for the induction of TRAIL mRNA by IFN-beta

scientific article

Requirement of phosphoinositide 3-kinase and Akt for interferon-beta-mediated induction of the beta-R1 (SCYB11) gene

scientific article (publication date: 11 October 2002)

Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1 Variant

scientific article published on 17 October 2018

Roles of IKK-beta, IRF1, and p65 in the activation of chemokine genes by interferon-gamma

scientific article published on December 2009

SIV/SHIV Infection Triggers Vascular Inflammation, Diminished Expression of Krüppel-like Factor 2 and Endothelial Dysfunction.

scientific article published on 15 December 2015

STAT-phosphorylation-independent induction of interferon regulatory factor-9 by interferon-beta

scientific article

Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues

scientific article published on 17 March 2008

Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice

scientific article

Selective leukocyte chemoattractants emerge from the primeval sup(ernatants)

scientific article published on 01 November 2005

Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling

scientific article published on 17 June 2019

Severe disease, unaltered leukocyte migration, and reduced IFN-gamma production in CXCR3-/- mice with experimental autoimmune encephalomyelitis

scientific article published in April 2006

Should We Stop Saying 'Glia' and 'Neuroinflammation'?

scientific article

Single-cell transcriptomic analysis of Alzheimer's disease

scientific article published on 01 May 2019

Snip-snip, kill-kill: truncated SDF-1 and HIV-associated neurodegeneration ⬇️

scientific article published on October 1, 2003

Spatiotemporal ablation of CXCR2 on oligodendrocyte lineage cells: Role in myelin repair.

scientific article

Specks of insight into Alzheimer's disease.

scientific article

Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?

scientific article

Sphingosine 1-phosphate signaling at the blood-brain barrier

scientific article published in May 2015

Steroid-responsive encephalopathy associated with autoimmune thyroiditis and primary CNS demyelination

scientific article published on 02 November 2004

Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression

scientific article published on 16 November 2012

Systemic lipopolysaccharide induces cochlear inflammation and exacerbates the synergistic ototoxicity of kanamycin and furosemide

scientific article

T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis

scientific article published on 21 March 2016

TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation

article

TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons.

scientific article

TNF-alpha microinjection upregulates chemokines and chemokine receptors in the central nervous system without inducing leukocyte infiltration

scientific article

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

scientific article

TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy

scientific article published on 16 October 2017

Taking two TRAILS.

scientific article

Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution

scientific article published on October 2017

The CD4-Th1 model for multiple sclerosis: a critical [correction of crucial] re-appraisal

scientific article published on March 2004

The Epstein-Barr virus oncoprotein latent membrane protein 1 induces expression of the chemokine IP-10: importance of mRNA half-life regulation

scientific article

The MHP36 line of murine neural stem cells expresses functional CXCR1 chemokine receptors that initiate chemotaxis in vitro

scientific article published on 07 May 2007

The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.

scientific article

The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis

scientific article published in January 2004

The anatomical and cellular basis of immune surveillance in the central nervous system.

scientific article published on 20 August 2012

The blood-brain barrier

scientific article published on 01 January 2016

The blood-brain barrier as target of multiple sclerosis research and therapy. Report of an international scientific meeting, Würzburg, January 23/24, 2004.

scientific article published in July 2004

The blood–brain barrier, chemokines and multiple sclerosis ⬇️

scientific article published on 06 August 2010

The chemokine receptor CXCR2 controls positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration

scientific article (publication date: 9 August 2002)

The expression and function of chemokines involved in CNS inflammation

scientific article

The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood

scientific article published on 11 November 2011

The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms

scientific article

The myeloid cells of the central nervous system parenchyma ⬇️

scientific article published on November 11, 2010

The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system

scientific article published in May 2006

The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE).

scientific article

The role of cell type-specific responses in IFN-β therapy of multiple sclerosis

scientific article published on 21 November 2011

The roles of chemokine CXCL12 in embryonic and brain tumor angiogenesis

scientific article

The roles of inflammation and immune mechanisms in Alzheimer's disease

scientific article published on 30 May 2016

Three or more routes for leukocyte migration into the central nervous system

scientific article

To Sleep, Perchance to Survive?

scientific article published on 15 March 2019

Transgenic expression of CCL2 in the central nervous system prevents experimental autoimmune encephalomyelitis

scientific article published on 11 November 2004

Translating research into treatments

scientific article published on 04 June 2008

Traumatic brain injury in hTau model mice: Enhanced acute macrophage response and altered long-term recovery.

scientific article published on 31 August 2017

Treatment of experimental autoimmune encephalomyelitis with the chemokine receptor antagonist Met-RANTES.

scientific article published in July 2002

Treatment with soluble tumor necrosis factor receptor (sTNFR):Fc/p80 fusion protein ameliorates relapsing-remitting experimental autoimmune encephalomyelitis and decreases chemokine expression

scientific article published on 01 September 2004

Turning over the Chance card on MS susceptibility

scientific article published on 01 July 2010

Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites

scientific article

VCAM-1-positive microglia target oligodendrocytes at the border of multiple sclerosis lesions

scientific article

VEGF-mediated inflammation precedes angiogenesis in adult brain

scientific article published in June 2004

alpha4 Integrin/FN-CS1 mediated leukocyte adhesion to brain microvascular endothelial cells under flow conditions

scientific article

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