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List of works by Michele De Palma

A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships

scientific article published on 21 April 2009

A niche role for periostin and macrophages in glioblastoma

scientific article published in February 2015

A role for angiopoietin-2 in organ-specific metastasis

scientific article published in August 2013

Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion.

scientific article published on 2 March 2011

Angiopoietin-2 TIEs Up Macrophages in Tumor Angiogenesis ⬇️

scientific article published on May 16, 2011

Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions.

scientific article published on 8 June 2010

Antagonizing metastasis

scientific article published in April 2010

Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice

scientific article published on 01 March 2020

Assessing metastasis risk after pre-operative anti-angiogenic therapy

scientific article published on 12 November 2014

Bimodal CD40/Fas-Dependent Crosstalk between iNKT Cells and Tumor-Associated Macrophages Impairs Prostate Cancer Progression.

scientific article published in March 2018

Biology and therapeutic targeting of tumour-associated macrophages

scientific article published on 21 February 2020

CD4+ T Cell Activation and Vascular Normalization: Two Sides of the Same Coin?

scientific article published on 01 May 2017

Cancer Metastasis: Perivascular Macrophages Under Watch.

scientific article

Cancer: Macrophages limit chemotherapy

scientific article published on 01 April 2011

Cellular magnetic resonance with iron oxide nanoparticles: long-term persistence of SPIO signal in the CNS after transplanted cell death.

scientific article published on 13 May 2014

Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models

scientific article published on 31 December 2018

Circulating Endothelial Progenitors and Tumor Resistance to Vascular-Targeting Therapies ⬇️

scientific article published on 01 May 2012

Consensus guidelines for the use and interpretation of angiogenesis assays

article

Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells

scientific article

DICERing macrophages for reprogramming TAMs

scientific article published on 5 August 2016

Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade.

scientific article

EVIR: chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens.

scientific article

Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors

scientific article published on 18 February 2010

Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells

scientific article

Engineering dendritic cell vaccines to improve cancer immunotherapy

scientific article published on 27 November 2019

Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis

scientific article

FcRgamma activation regulates inflammation-associated squamous carcinogenesis.

scientific article

Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression

scientific article

Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages.

scientific article

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF

scientific article

Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer.

scientific article published on 27 February 2007

In vivo targeting of tumor endothelial cells by systemic delivery of lentiviral vectors.

scientific article published in August 2003

Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer

scientific article published on 01 May 2019

Lymphoma Chemotherapy: Hungry Macrophages Strike the Final Blow

scientific article published on 01 July 2019

Macrophage interference on chemotherapy

scientific article published on 01 April 2019

Macrophage regulation of tumor angiogenesis: Implications for cancer therapy ⬇️

scientific article published on May 1, 2011

Macrophage regulation of tumor responses to anticancer therapies

scientific article

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

scientific article

Metastasis risk after anti-macrophage therapy

journal article; published in Nature on 2014-10-22

MicroRNA-mediated control of macrophages and its implications for cancer

scientific article published on 13 March 2013

Microenvironmental regulation of tumour angiogenesis

scientific article

Micromanaging restenosis by therapeutic inhibition of miR-92a

scientific article published on 31 July 2014

Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.

scientific article published in June 2019

Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapy

scientific article published on 30 December 2019

PHD2 regulates arteriogenic macrophages through TIE2 signalling

scientific article published on 25 April 2013

Partners in crime: VEGF and IL‐4 conscript tumour‐promoting macrophages ⬇️

scientific article published on March 22, 2012

Periostin Limits Tumor Response to VEGFA Inhibition

scientific article published in March 2018

Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy

scientific article published on 12 August 2015

Perivascular Macrophages Limit Permeability

scientific article published on 15 September 2016

Perivascular macrophages in health and disease

scientific article published on 01 November 2018

Precision Targeting of Tumor Macrophages with a CD206 Binding Peptide.

scientific article published on 7 November 2017

Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.

scientific article published on 21 November 2016

Proangiogenic Tie2(+) macrophages infiltrate human and murine endometriotic lesions and dictate their growth in a mouse model of the disease.

scientific article

Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells

scientific article published on 12 November 2004

Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity

scientific article published on 7 February 2018

Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches.

scientific article published on 28 March 2013

Regulation of macrophage arginase expression and tumor growth by the Ron receptor tyrosine kinase

scientific article

Reprogramming Tumor Blood Vessels for Enhancing Immunotherapy

scientific article published on 27 October 2017

Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade.

scientific article

Role of haematopoietic cells and endothelial progenitors in tumour angiogenesis

scientific article published on 27 June 2006

Sequential Bone-Marrow Cell Delivery of VEGFA/S1P Improves Vascularization and Limits Adverse Cardiac Remodeling After Myocardial Infarction in Mice

scientific article published on 27 March 2019

Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity

scientific article published on 13 June 2016

Systemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor models

scientific article published on 4 January 2011

T cell-induced CSF1 promotes melanoma resistance to PD1 blockade.

scientific article published in April 2018

TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice

scientific article

TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb ⬇️

scientific article published on 07 May 2013

TIE2-expressing monocytes: A novel cellular biomarker for hepatocellular carcinoma? ⬇️

scientific article published on March 6, 2013

TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

scientific article

Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression

scientific article published on 10 February 2016

Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells

scientific article published on 12 May 2003

Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.

scientific article

Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2.

scientific article

The biology of personalized cancer medicine: Facing individual complexities underlying hallmark capabilities ⬇️

scientific article published on 04 February 2012

The interplay between macrophages and angiogenesis in development, tissue injury and regeneration

scientific article published on January 2011

Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.

scientific article published in September 2005

Tie2-expressing monocytes (TEMs): novel targets and vehicles of anticancer therapy?

scientific article published on 10 April 2009

Tie2-expressing monocytes and tumor angiogenesis: regulation by hypoxia and angiopoietin-2.

scientific article published on September 2007

Tie2-expressing monocytes: regulation of tumor angiogenesis and therapeutic implications

scientific article

Transduction of a gene expression cassette using advanced generation lentiviral vectors

scientific article published on 01 January 2002

Transplanted neural stem/precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord.

scientific article published on 23 January 2012

Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis

scientific article published on October 2008

miR-135a Inhibits Cancer Stem Cell-Driven Medulloblastoma Development by Directly Repressing Arhgef6 Expression

scientific article published in May 2015

miR-511-3p modulates genetic programs of tumor-associated macrophages

scientific journal article

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