Search filters

List of works by William J Breslin

A framework for assessing risks to children from exposure to environmental agents

scientific article

An Enhanced Pre- and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody

scientific article published in June 2015

Assessment of fetal exposure risk following seminal excretion of a therapeutic IgG4 (T-IgG4) monoclonal antibody using a rabbit model

scientific article published on 23 May 2014

Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects

scientific article

Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects

scientific article

Considerations in assessing the developmental and reproductive toxicity potential of biopharmaceuticals

scientific article published on June 2009

Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody

scientific article

Fertility and Embryo-Fetal Development Assessment in Rats and Rabbits with Evacetrapib: A Cholesteryl Ester Transfer Protein Inhibitor

scientific article published on 22 March 2017

Fertility and developmental toxicity assessment in rats and rabbits with LY500307, a selective estrogen receptor beta (ERβ) agonist

scientific article

Frozen-sectioning yields similar results as traditional methods for fetal cephalic examination in the rat.

scientific article

Hazard identification and predictability of children's health risk from animal data

scientific article

In vitro testicular toxicity models: opportunities for advancement via biomedical engineering techniques

journal article published in 2013

Incidence and nature of testicular toxicity findings in pharmaceutical development.

scientific article published on December 2011

Introduction to the HESI DART Drugs in Semen Consortium

scientific article published on 04 May 2014

NTP-CERHR Expert Panel Update on the Reproductive and Developmental Toxicity of di(2-ethylhexyl) phthalate

scientific article published on October 2006

PDGFRα monoclonal antibody: Assessment of embryo-fetal toxicity and time-dependent placental transfer of a murine surrogate antibody of olaratumab in mice

scientific article published on 27 October 2018

Placental transfer of Fc-containing biopharmaceuticals across species, an industry survey analysis

scientific article published in December 2013

Potential seminal transport of pharmaceuticals to the conceptus

scientific article

Prenatal and Postnatal Assessment in Rabbits with Evacetrapib: A Cholesteryl Ester Transfer Protein Inhibitor

scientific article published on 31 March 2017

Reprint of "Potential seminal transport of pharmaceuticals to the conceptus"

scientific article

Summary of the HESI consortium studies exploring circulating inhibin B as a potential biomarker of testis damage in the rat.

scientific article published on 30 January 2013

TGF-β1 monoclonal antibody: Assessment of embryo-fetal toxicity in rats and rabbits

scientific article published on 12 August 2016

The inhibin B (InhB) response to the testicular toxicants mono-2-ethylhexyl phthalate (MEHP), 1,3 dinitrobenzene (DNB), or carbendazim (CBZ) following short-term repeat dosing in the male rat.

scientific article