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List of works by David A. Jones

A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC).

scientific article

A two-step model for colon adenoma initiation and progression caused by APC loss

scientific article published on May 2009

APC and DNA Demethylation in Cell Fate Specification and Intestinal Cancer ⬇️

scientific article published on January 1, 2013

Active BRAF-V600E is the key player in generation of a sessile serrated polyp-specific DNA methylation profile.

scientific article published on 28 March 2018

Adenomatous polyposis coli control of C-terminal binding protein-1 stability regulates expression of intestinal retinol dehydrogenases

scientific article published on 6 October 2006

Adenomatous polyposis coli control of retinoic acid biosynthesis is critical for zebrafish intestinal development and differentiation

scientific article published on 8 September 2004

Association of Sulindac and Erlotinib vs Placebo With Colorectal Neoplasia in Familial Adenomatous Polyposis: Secondary Analysis of a Randomized Clinical Trial

scientific article published on 8 February 2018

Cholinesterase Inhibitory Arisugacins L-Q from a Penicillium sp. Isolate Obtained through a Citizen Science Initiative and Their Activities in a Phenotype-Based Zebrafish Assay

scientific article published on 21 August 2019

DNA Demethylase Activity Maintains Intestinal Cells in an Undifferentiated State Following Loss of APC ⬇️

scientific article published on September 17, 2010

DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.

scientific article published on December 2008

DNA methylation profiling in zebrafish

scientific article published on January 1, 2011

DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling

scientific article published on September 2004

Discovery of biologically active oncologic and immunologic small molecule therapies using zebrafish: overview and example of modulation of T cell activation

scientific article published in March 2013

Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish

scientific article published on February 2007

Dnmt3 and G9a cooperate for tissue-specific development in zebrafish

scientific article

Dual roles for adenomatous polyposis coli in regulating retinoic acid biosynthesis and Wnt during ocular development

scholarly article

Effect of Sulindac and Erlotinib vs Placebo on Duodenal Neoplasia in Familial Adenomatous Polyposis: A Randomized Clinical Trial

scientific article

Epigenetic regulation of colon cancer and intestinal stem cells ⬇️

scientific article published on February 8, 2013

Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation

scientific article

Evaluation of pyridoacridine alkaloids in a zebrafish phenotypic assay

scientific article

Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors

scientific article published on 21 October 2004

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas

scientific article published on 11 June 2019

Genomic Landscape of Colorectal Mucosa and Adenomas

scientific article published on 24 May 2016

Identification of a gadd45beta 3' enhancer that mediates SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor beta

scientific article (publication date: 13 February 2004)

Juxtaposition of Chemical and Mutation-Induced Developmental Defects in Zebrafish Reveal a Copper-Chelating Activity for Kalihinol F ⬇️

scientific article published on June 20, 2013

Multivariate exploratory tools for microarray data analysis ⬇️

scientific article published on October 1, 2003

New perspectives on APC control of cell fate and proliferation in colorectal cancer

scientific article published on 16 August 2009

Reactivating the expression of methylation silenced genes in human cancer

scientific article

Retinoic acid inhibits beta-catenin through suppression of Cox-2: a role for truncated adenomatous polyposis coli

scientific article published on 2 August 2007

SUMOylation Regulates Growth Factor Independence 1 in Transcriptional Control and Hematopoiesis.

scientific article published on 7 March 2016

The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion.

scientific article

The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid

scientific article published on 14 May 2006

The role of cyclooxygenase-2 and prostaglandins in colon cancer

scientific article published on September 2006

The tumor suppressor adenomatous polyposis coli and caudal related homeodomain protein regulate expression of retinol dehydrogenase L

scientific article

The zebrafish retinol dehydrogenase, rdh1l, is essential for intestinal development and is regulated by the tumor suppressor adenomatous polyposis coli

scientific article published on 20 June 2005

Toxic effects of a methanolic coal dust extract on fish early life stage

scientific article published on 05 April 2019

Transcription factor Oct1 is a somatic and cancer stem cell determinant

scientific article

Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development

scientific article published on August 2006

Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development

scientific article

Zebrafish screen identifies novel compound with selective toxicity against leukemia.

scientific article

p53-inducible ribonucleotide reductase (p53R2/RRM2B) is a DNA hypomethylation-independent decitabine gene target that correlates with clinical response in myelodysplastic syndrome/acute myelogenous leukemia ⬇️

scientific article

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