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List of works by Murray W Huff

A novel inhibitor of oxidosqualene:lanosterol cyclase inhibits very low-density lipoprotein apolipoprotein B100 (apoB100) production and enhances low-density lipoprotein apoB100 catabolism through marked reduction in hepatic cholesterol content

scientific article

A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia

scientific article published on 05 August 2009

APOC1 T45S polymorphism is associated with reduced obesity indices and lower plasma concentrations of leptin and apolipoprotein C-I in aboriginal Canadians

scientific article

ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia

scientific article published on 5 January 2017

An increased burden of common and rare lipid-associated risk alleles contributes to the phenotypic spectrum of hypertriglyceridemia

scientific article published on 19 May 2011

Ankyrin G overexpression in Hutchinson-Gilford progeria syndrome fibroblasts identified through biological filtering of expression profiles

scientific article

Antiatherogenic properties of flavonoids: implications for cardiovascular health.

scientific article

Apolipoprotein C-III: going back to the future for a lipid drug target

scientific article published in May 2013

Association between the -455T>C promoter polymorphism of the APOC3 gene and the metabolic syndrome in a multi-ethnic sample

scientific article

Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample

scientific article published on 13 March 2008

Avasimibe Pfizer.

scientific article

Bempedoic Acid Lowers Low-Density Lipoprotein Cholesterol and Attenuates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (LDLR+/- and LDLR-/- ) Yucatan Miniature Pigs.

scientific article published on 15 February 2018

Canadian global village reality: anthropometric surrogate cutoffs and metabolic abnormalities among Canadians of East Asian, South Asian, and European descent

scientific article

Cholesterol absorption inhibitors as a therapeutic option for hypercholesterolaemia

scientific article published on November 2006

Citrus Flavonoids and the Prevention of Atherosclerosis ⬇️

scientific article published on December 1, 2012

Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis

scientific article published on 4 May 2016

Citrus flavonoids and lipid metabolism ⬇️

scientific article published on February 1, 2013

Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: a novel mechanism for the attenuation of foam cell formation

scientific article published on 25 September 2003

Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia

scientific article published on December 2011

Fibroblast growth factor 21 reduces the severity of cerulein-induced pancreatitis in mice

scientific article published on 5 August 2009

G-protein estrogen receptor as a regulator of low-density lipoprotein cholesterol metabolism: cellular and population genetic studies

scientific article

Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor

scientific article published on 27 June 2008

Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters.

scientific article

Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes

scientific article

Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr-/- mice

scientific article published on 15 July 2018

Lipid incorporation inhibits Src-dependent assembly of fibronectin and type I collagen by vascular smooth muscle cells

scientific article

Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear

scientific article

NPC1L1: evolution from pharmacological target to physiological sterol transporter

scientific article published on 14 September 2006

Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice

scientific article published on 28 January 2010

Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr⁻/⁻ mice.

scientific article published on 26 December 2012

Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance

scientific article

Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21.

scientific article published on 16 March 2015

Nobiletin Attenuates VLDL Overproduction, Dyslipidemia, and Atherosclerosis in Mice With Diet-Induced Insulin Resistance ⬇️

scientific article published on April 6, 2011

PCSK9: Regulation and Target for Drug Development for Dyslipidemia

scientific article

PPARδ activation attenuates hepatic steatosis in Ldlr-/- mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity

scientific article

Peroxisome proliferator-activated receptor δ: a multifaceted metabolic player

scientific article published on April 2013

Polygenic determinants of severe hypertriglyceridemia

scientific article

Prevention of Diet-Induced Metabolic Dysregulation, Inflammation, and Atherosclerosis in Ldlr-/- Mice by Treatment With the ATP-Citrate Lyase Inhibitor Bempedoic Acid

scientific article published on 2 February 2017

Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation ⬇️

scientific article published on May 30, 2012

Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux

scientific article

Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol

scientific article

Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms

scientific article

Successful pregnancy outcome in a patient with severe chylomicronemia due to compound heterozygosity for mutant lipoprotein lipase

scientific article published in March 2002

The Oxysterol 24 (S) ,25‐Epoxycholesterol Attenuates Human Smooth Muscle–Derived Foam Cell Formation Via Reduced Low‐Density Lipoprotein Uptake and Enhanced Cholesterol Efflux ⬇️

scientific article published on June 22, 2012

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