List of works - Kazuaki Chayama

<em>In vitro</em> analysis of hepatic stellate cell activation influenced by transmembrane 6 superfamily 2 polymorphism

scientific article published on 12 November 2020

A Comparison of Adrenalectomy and Eplerenone on Vascular Function in Patients with Aldosterone-producing Adenoma

scientific article published on 20 August 2020

A Cost-Effectiveness Analysis of Glecaprevir/Pibrentasvir Versus Existing Direct-Acting Antivirals to Treat Chronic Hepatitis C in Japan

scientific article published on 05 December 2019

A Data Mining-based Prognostic Algorithm for NAFLD-related Hepatoma Patients: A Nationwide Study by the Japan Study Group of NAFLD.

scientific article published on 11 July 2018

A MAVS/TICAM-1-independent interferon-inducing pathway contributes to regulation of hepatitis B virus replication in the mouse hydrodynamic injection model.

scientific article published on 8 August 2014

A Patient with CTLA-4 Haploinsufficiency Presenting Gastric Cancer

scientific article

A case of Crohn's disease with hydronephrosis caused by ureteropelvic junction obstruction.

scientific article

A case of advanced HCC treated with lenvatinib after hepatic arterial infusion chemotherapy combined with radiation therapy treatment for portal vein tumor thrombosis in the main trunk

scientific article published on 23 January 2020

A case of chronic hepatitis C with pancreas divisum and acute pancreatitis during combination treatment with telaprevir/peginterferon/ribavirin

scientific article published in October 2014

A case of congenital absence of the portal vein

scientific article

A case of fulminant hepatic failure caused by hepatitis E virus

scientific article

A case of intrahepatic cholangiocarcinoma with liver cirrhosis presenting atypical images

scientific article published on August 1, 1992

A case of large cell neuroendocrine carcinoma of the stomach with multiple liver metastases

scientific article published on 01 August 2016

A case of latent primary biliary cirrhosis

scientific article published on 01 March 2004

A case of multiple hepatic peribiliary cysts which contributed to the obstructive jaundice and led to liver failure at the young man with von Recklinghausen's disease

scientific article published on 26 May 2006

A case of primary malignant melanoma of the esophagus with a widely expanded surface area

scientific article published on 18 March 2019

A case of syndrome of inappropriate secretion of antidiuretic hormone following transarterial embolization with cisplatin

scientific article published on 01 September 2014

A case with life-threatening secondary sclerosing cholangitis caused by nivolumab

scientific article published on 16 November 2020

A classification system of echogenicity for gastrointestinal neoplasms

scientific article published on 25 July 2005

A combination of the Helicobacter pylori stool antigen test and urea breath test is useful for clinical evaluation of eradication therapy: a multicenter study

scientific article published in August 2005

A comparison of 4-Fr with 5-Fr endoscopic nasopancreatic drainage catheters: A randomized, controlled trial

scientific article published on 10 February 2016

A comparison of low-dose and standard-dose oral estrogen on forearm endothelial function in early postmenopausal women

scientific article published in March 2003

A computer system to be used with laser-based endoscopy for quantitative diagnosis of early gastric cancer

scientific article

A first case of hepatic angiosarcoma treated with recombinant interleukin-2.

scientific article published on December 2011

A frameshift mutation of beta subunit of epithelial sodium channel in a case of isolated Liddle syndrome

scientific article published in December 2002

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians

scientific article published on 6 April 2009

A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region

scientific journal article

A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population

scientific article published on 12 July 2011

A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1

scientific journal article

A huge metastatic liver tumor from leiomyosarcoma of the inferior vena cava: report of a case

scientific article published on 30 November 2011

A low-calorie diet improves endothelium-dependent vasodilation in obese patients with essential hypertension

scientific article

A multicenter, open-label, dose-ranging study to exploratively evaluate the efficacy, safety, and dose-response of tolvaptan in patients with decompensated liver cirrhosis

scientific article published on 13 April 2010

A multivariate analysis of risk factors for hepatocellular carcinogenesis: A prospective observation of 795 patients with viral and alcoholic cirrhosis ⬇️

scientific article published on July 1, 1993

A nationwide survey on non-B, non-C hepatocellular carcinoma in Japan: 2011-2015 update

scientific article published on 29 November 2018

A nonsynonymous polymorphism in semaphorin 3A as a risk factor for human unexplained cardiac arrest with documented ventricular fibrillation

scientific article

A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections.

scientific article published on 16 October 2013

A novel noninvasive and simple method for assessment of endothelial function: enclosed zone flow-mediated vasodilation (ezFMD) using an oscillation amplitude measurement.

scientific article published on 6 June 2013

A novel noninvasive diagnostic method for nonalcoholic steatohepatitis using two glycobiomarkers

scientific article published on 25 August 2015

A nuclear receptor ligand down-regulates cytosolic phospholipase A2 expression to reduce bile acid-induced cyclooxygenase 2 activity in cholangiocytes: implications of anticarcinogenic action of farnesoid X receptor agonists

scientific article published in March 2005

A nuclear receptor-mediated choleretic action of fibrates is associated with enhanced canalicular membrane fluidity and transporter activity mediating bile acid-independent bile secretion

scientific article

A phase III study of the efficacy and safety of meropenem in patients with febrile neutropenia

scientific article published on August 1, 2012

A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.

scientific article published on 31 January 2009

A proposed system for the nomenclature of hepatitis C viral genotypes

article by Peter Simmonds et al published May 1994 in Hepatology

A randomized controlled trial of interferon-alpha in patients with cirrhosis caused by 2a/2b genotype hepatitis C virus ⬇️

scientific article published on May 1, 1998

A randomized phase II trial of intra-arterial chemotherapy using SM-11355 (Miriplatin) for hepatocellular carcinoma

scientific article

A randomized trial of daclatasvir with peginterferon alfa-2b and ribavirin for HCV genotype 1 infection

scientific article published on 22 January 2014

A randomized, controlled study of peginterferon lambda-1a/ribavirin ± daclatasvir for hepatitis C virus genotype 2 or 3.

scientific article published on 19 August 2016

A second attack of cholestasis associated with erythropoietic protoporphyria was successfully treated by plasma exchange and blood transfusion

scientific article published on 10 June 2014

A simple clinical scoring system using ferritin, fasting insulin, and type IV collagen 7S for predicting steatohepatitis in nonalcoholic fatty liver disease

scientific article published on 15 September 2010

A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.

scientific article published on 18 November 2010

A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer

scientific article published on 18 February 2004

A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer

scientific article published on 30 September 2004

A spontaneous Type 1 electrocardiogram pattern in lead V2 is an independent predictor of ventricular fibrillation in Brugada syndrome

scientific article published on 31 January 2010

A translational study of resistance emergence using sequential direct-acting antiviral agents for hepatitis C using ultra-deep sequencing.

scientific article published on 30 July 2013

A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers

scientific article

A watch-and-wait policy versus rituximab-combined chemotherapy in Japanese patients with intestinal follicular lymphoma

scientific article published on 29 January 2018

A water-soluble extract from culture medium of Ganoderma lucidum mycelia suppresses the development of colorectal adenomas

scientific article published on 01 March 2010

ADH1B and ALDH2 are associated with metachronous SCC after endoscopic submucosal dissection of esophageal squamous cell carcinoma

scientific article published on 31 March 2016

ADIPOQ polymorphisms are associated with insulin resistance in Japanese women

scientific article published on 31 March 2015

AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl(4).

scientific article published in August 2003

Abatacept treatment for patients with severe acute hepatitis caused by hepatitis B virus infection - Pilot study

scientific article published on 16 November 2020

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

scientific article published on 25 November 2021

Ablation of the bach1 gene leads to the suppression of atherosclerosis in bach1 and apolipoprotein E double knockout mice

scientific article published in April 2008

Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice.

scientific article published on 23 September 2009

Accumulation of refractory factors for pegylated interferon plus ribavirin therapy in older female patients with chronic hepatitis C.

scientific article published on 7 October 2010

Achievement of sustained viral response after switching treatment from pegylated interferon α-2b to α-2a and ribavirin in patients with recurrence of hepatitis C virus genotype 1 infection after liver transplantation: a case report.

scientific article published on 25 August 2011

Activation of Akt is associated with poor prognosis and chemotherapeutic resistance in pediatric B‐precursor acute lymphoblastic leukemia ⬇️

scientific article published on December 19, 2011

Acute HBV infection in humanized chimeric mice has multiphasic viral kinetics

scientific article published on 23 March 2018

Acute moderate-intensity exercise induces vasodilation through an increase in nitric oxide bioavailiability in humans

scientific article published on 01 August 2007

Adoptive immunotherapy with liver allograft–derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice

scientific article

Adrenomedullin causes coronary vasodilation in humans: effects of inhibition of nitric oxide synthesis

scientific article

Advanced colorectal carcinoma smaller than 10 mm in maximum diameter with special reference to clinicopathologic and molecular features: a report of 3 cases

scientific article published on 01 August 2002

Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells

scientific article published on 06 May 2008

Advanced liver fibrosis effects on the response to sofosbuvir-based antiviral therapies for chronic hepatitis C

scientific article published on 13 August 2018

Advanced method for evaluation of gastric cancer risk by serum markers: determination of true low-risk subjects for gastric neoplasm

scientific article published on 11 November 2013

Advances of an internal treatment for early colorectal carcinoma

scientific article published in May 2004

Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer

scientific article published on 20 September 2006

Advantages of endoscopic submucosal dissection versus endoscopic oblique aspiration mucosectomy for superficial esophageal tumors

scientific article published in February 2011

Aged garlic extract has potential suppressive effect on colorectal adenomas in humans

scientific article published on 01 March 2006

Aggressive angiomyxoma of the liver: a case report and literature review

scientific article published on 23 August 2017

Aging and hypertension are independent risk factors for reduced number of circulating endothelial progenitor cells

scientific article published on 11 September 2008

Airway stenting for tracheal obstruction due to lymph node metastasis of hepatocellular carcinoma

scientific article

Alanine aminotransferase and HCV-RNA responses following interferon therapy of HCV-RNA positive chronic hepatitis

scientific article published on October 1, 1992

Alcohol Use Disorders Identification Test-consumption Predicts the Risk of Excessive Alcohol Consumption After Liver Transplantation

scientific article published on 01 July 2019

Alpha-fetoprotein and des-gamma-carboxy-prothrombin at twenty-four weeks after interferon-based therapy predict hepatocellular carcinoma development

scientific article

Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment

scientific article published on 8 June 2012

Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy

scientific article published on 5 July 2011

Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.

scientific article published in August 2010

Amino acid substitutions in core and NS5A regions of the HCV genome can predict virological decrease with pegylated interferon plus ribavirin therapy

scientific article published in January 2010

Amphipathic DNA Polymers Inhibit Hepatitis C Virus Infection by Blocking Viral Entry

scientific article

An Analysis of Surgical Treatment for the Spontaneous Rupture of Hepatocellular Carcinoma.

scientific article published on 19 November 2015

An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

scientific article

Analysis of Hepatitis C Virus Genotype 1b Resistance Variants in Japanese Patients Treated with Paritaprevir-Ritonavir and Ombitasvir

scientific article

Analysis of Post-Progression Survival in Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib

scientific article published on 03 September 2020

Angiogenic switch occurs during the precancerous stage of human esophageal squamous cell carcinoma.

scientific article published on February 2004

Angiotensin II participates in hepatic inflammation and fibrosis through MCP-1 expression

scientific article

Angiotensin II type I receptor blocker and endothelial function in humans: role of nitric oxide and oxidative stress

scientific article

Angiotensin II-induced osteopontin expression in vascular smooth muscle cells involves Gq/11, Ras, ERK, Src and Ets-1.

scientific article published in May 2008

Animal model for study of human hepatitis viruses

scientific article published on January 2011

Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis

scientific article published on 08 June 2006

Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model.

scientific article

Antibiotic prophylaxis for endoscopic retrograde chlangiopancreatography increases the detection rate of drug-resistant bacteria in bile

scholarly article by Tomoyuki Minami et al published September 2014 in Journal of Hepato-biliary-Pancreatic Sciences

Antibodies to Helicobacter pylori and CagA protein are associated with the response to antibacterial therapy in patients with H. pylori-positive API2-MALT1-negative gastric MALT lymphoma

scientific article published on 25 March 2009

Antiviral activity, dose-response relationship, and safety of entecavir following 24-week oral dosing in nucleoside-naive Japanese adult patients with chronic hepatitis B: a randomized, double-blind, phase II clinical trial

scientific article published on 23 May 2009

Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection

scientific article

Antiviral effects of peginterferon alpha-2b and ribavirin following 24-week monotherapy of telaprevir in Japanese hepatitis C patients

scientific article published on 10 May 2011

Apolipoprotein E phenotype affects the malondialdehyde-modified LDL concentration and forearm endothelial function in postmenopausal women

scientific article published in November 2004

Area of Submucosal Invasion and Width of Invasion Predict Lymph Node Metastasis in pT1 Colorectal Cancers

scientific article published in February 2016

Assessment of Outcome of Hepatic Arterial Infusion Chemotherapy in Patients with Advanced Hepatocellular Carcinoma by the Combination of RECIST and Tumor Markers

Assessment of trypsinogen-2 levels as an early diagnostic for post-endoscopic retrograde cholangiopancreatography pancreatitis

scientific article published on 01 November 2011

Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography

scientific article published on 01 March 2012

Association between variants in the interferon lambda 4 locus and substitutions in the hepatitis C virus non-structural protein 5A.

scientific article published on 4 April 2015

Association of Body Mass Index with Endothelial Function in Asian Men

scientific article published on 12 September 2020

Association of extremely high levels of high-density lipoprotein cholesterol with endothelial dysfunction in men

scientific article published on 20 June 2019

Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits

scientific article published on 01 May 2014

Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease

scientific article

Association of two polymorphisms of the IL28B gene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus.

scientific article published on 23 March 2012

Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH.

scientific article

Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property

scientific article published on 20 January 2012

Attention-getting sexually transmitted diseases: Hepatitis B

scientific article published in November 2007

Autologous bone marrow mononuclear cell implantation induces angiogenesis and bone regeneration in a patient with compartment syndrome

scientific article published on 01 October 2006

Autologous bone-marrow mesenchymal stem cell implantation and endothelial function in a rabbit ischemic limb model.

scientific article

Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia

scientific article published on 8 March 2004

Autologous bone-marrow mononuclear cell implantation reduces long-term major amputation risk in patients with critical limb ischemia: a comparison of atherosclerotic peripheral arterial disease and Buerger disease.

scientific article published on 04 January 2011

Availability of monitoring serum HBV DNA plus RNA during nucleot(s)ide analogue therapy

scientific article published on 3 April 2013

Bach1 Plays an Important Role in Angiogenesis Through Regulation of Oxidative Stress

scientific article published on 26 December 2020

Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model

scientific article published on 10 April 2010

Balloon-occluded retrograde transvenous obliteration for portal-systemic encephalopathy due to superior mesenteric-caval shunt via the right gonadal vein

scientific article

Balloon-occluded retrograde transvenous obliteration of gastric fundal varices with hemorrhage

scientific article published in May 2002

Basis of decreased risk of gastric cancer in severe atrophic gastritis with eradication of Helicobacter pylori

scientific article published on 7 December 2006

Beneficial effects of living-donor liver transplantation on esophageal varices

scientific article published on 24 December 2008

Bile acid promotes intestinal metaplasia and gastric carcinogenesis

scientific article

Bile-salt hydrophobicity is a key factor regulating rat liver plasma-membrane communication: relation to bilayer structure, fluidity and transporter expression and function ⬇️

scientific article published on November 1, 2001

Biliary complications after duct-to-duct biliary reconstruction in living-donor liver transplantation: causes and treatment

scientific article published in November 2007

Biphasic effect of HMG-CoA reductase inhibitor, pitavastatin, on vascular endothelial cells and angiogenesis

scientific article published in December 2005

Biphasic effect of alcohol intake on the development of fatty liver disease

scientific article

Borderline ankle-brachial index value of 0.91-0.99 is associated with endothelial dysfunction

scientific article published on 10 May 2014

Brachial artery diameter as a marker for cardiovascular risk assessment: FMD-J study.

scientific article

CASE REPORT: Clinical and virological analyses of a patient positive for hepatitis C virus‐RNA by branched DNA assay but negative for anti‐hepatitis C virus antibodies ⬇️

scientific article published on December 1, 1997

CD34+ progenitor cell transplantation from two HLA-mismatched healthy fathers to two infants with severe aplastic anemia

scientific article published on January 1, 1998

CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass.

scientific article published in October 2015

CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients

article

Calcium channel blocker and Rho-associated kinase activity in patients with hypertension

scientific article published on February 2011

Can surveillance colonoscopy be discontinued in an elderly population with diminutive polyps?

scientific article published on 30 July 2019

Cardiac angiotensin II type 2 receptor activates the kinin/NO system and inhibits fibrosis

scientific article published on 01 January 2003

Cardiac glands hyperplastic polyp of the stomach

scientific article published on 01 September 2005

Carvedilol improves endothelium-dependent vasodilation in patients with dilated cardiomyopathy

scientific article published on February 2007

Case reports of portal vein thrombosis and bile duct stenosis after stereotactic body radiation therapy for hepatocellular carcinoma

scholarly article by Shigeo Takahashi et al published October 2014 in Hepatology Research

Causal role of Helicobacter pylori infection and eradication therapy in gastric carcinogenesis

scientific article

Cavernous hemangioma in the ascending colon treated by endoscopic mucosal resection

scientific article

Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants

scientific article published on 6 July 2010

Change in Imaging Findings on Angiography-Assisted CT During Balloon-Occluded Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma

scientific article published on 28 December 2015

Change in malpractice claims in Japanese gastroenterological practice

scientific article published in January 2012

Characteristic Features of Cholangiocarcinoma Complicating Primary Sclerosing Cholangitis

scientific article published on 01 May 2014

Characteristic epithelium with low-grade atypia appears on the surface of gastric cancer after successful Helicobacter pylori eradication therapy

scientific article published on 28 April 2014

Characteristic magnifying narrow-band imaging features of colorectal tumors in each growth type

scientific article published on 04 December 2012

Characteristics and Early Diagnosis of Gastric Cancer Discovered after Helicobacter pylori Eradication

scientific article published on 24 April 2020

Characteristics of esophageal squamous cell carcinomas and lugol-voiding lesions in patients with head and neck squamous cell carcinoma

scientific article published in February 2010

Characteristics of gastric cancer in negative test of serum anti-Helicobacter pylori antibody and pepsinogen test: a multicenter study

scientific article

Characteristics of metachronous gastric tumors after endoscopic submucosal dissection for gastric intraepithelial neoplasms.

scientific article published on 11 February 2014

Characteristics of non-obese non-alcoholic fatty liver disease: Effect of genetic and environmental factors

scientific article published on 05 April 2016

Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers.

scientific article published on 18 May 2018

Characterization of colorectal tumors using narrow-band imaging magnification: combined diagnosis with both pit pattern and microvessel features

scientific article published in September 2010

Characterization of miR-122-independent propagation of HCV.

scientific article

Characterization of recombinant Flaviviridae viruses possessing a small reporter-tag

scientific article published in November 2017

Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir

scientific article published on 22 November 2012

Cheilitis granulomatosa as an early manifestation of Crohn's disease

scientific article published on 21 May 2009

Choleretic action of diosgenin is based upon the increases in canalicular membrane fluidity and transporter activity mediating bile acid independent bile flow

scientific article published on 01 March 2003

Choline Deficiency Causes Colonic Type II Natural Killer T (NKT) Cell Loss and Alleviates Murine Colitis under Type I NKT Cell Deficiency

scientific article

Chromosomal Abnormalities in Human Lymphocytes after Computed Tomography Scan Procedure

scientific article published on 24 July 2018

Chromosomal and microsatellite instability in sporadic gastric cancer

scientific article published on 01 July 2004

Chromosome 4q25 Variant rs6817105 Bring Sinus Node Dysfunction and Left Atrial Enlargement

scientific article published in Scientific Reports

Chronic hepatitis B in patients coinfected with human immunodeficiency virus in Japan: a retrospective multicenter analysis

scientific article published on 4 July 2012

Chronic hepatitis C in patients co-infected with human immunodeficiency virus in Japan: a retrospective multicenter analysis

scientific article published on 7 April 2009

Chronic kidney disease is associated with vascular smooth muscle dysfunction but not with endothelial dysfunction.

scientific article

Cigarette smoking abolishes ischemic preconditioning-induced augmentation of endothelium-dependent vasodilation

scientific article published on 23 February 2009

Cigarette smoking promotes atrophic gastritis in Helicobacter pylori-positive subjects.

scientific article published in March 2002

Circadian variation of blood pressure and endothelial function in patients with essential hypertension:a comparison of dippers and non-dippers

scientific article published in December 2002

Circulating Tumor DNA Analysis for Liver Cancers and Its Usefulness as a Liquid Biopsy

scientific article published on 17 June 2015

Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib

scientific article published on 20 May 2020

Circulating level of pigment epithelium-derived factor is associated with vascular function and structure: A cross-sectional study

scientific article published on 3 October 2016

Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B.

scientific article published in May 2013

Classification of corkscrew collaterals in thromboangiitis obliterans (Buerger's disease): relationship between corkscrew type and prevalence of ischemic ulcers

scientific article published on 9 June 2010

Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations

scientific article published on 26 February 2020

Clinical Features and Genomic Characterization of Post-Colonoscopy Colorectal Cancer

scientific article published on 01 October 2020

Clinical Significance of Reddish Depressed Lesions Observed in the Gastric Mucosa after Helicobacter pylori Eradication

scientific article

Clinical Usefulness of Dual Red Imaging in Gastric Endoscopic Submucosal Dissection: A Pilot Study

scientific article published on 03 September 2019

Clinical Usefulness of Serum Autotaxin for Early Prediction of Relapse in Male Patients with Type 1 Autoimmune Pancreatitis

scientific article published on 20 May 2020

Clinical Usefulness of the VS Classification System Using Magnifying Endoscopy with Blue Laser Imaging for Early Gastric Cancer

scientific article

Clinical Utility of Emergency Capsule Endoscopy for Diagnosing the Source and Nature of Ongoing Overt Obscure Gastrointestinal Bleeding

scientific article published on 01 December 2019

Clinical and genomic characteristics of mucosal signet-ring cell carcinoma in Helicobacter pylori-uninfected stomach

scientific article published on 29 July 2020

Clinical characteristics and natural history of patients with low-grade reflux esophagitis

scientific article published on 01 September 2002

Clinical characteristics of inflammatory bowel disease patients with immunoglobulin A nephropathy

scientific article published on 09 November 2020

Clinical characteristics of patients who developed hepatocellular carcinoma after hepatitis C virus eradication with interferon therapy: current status in Japan

scientific article published on January 2013

Clinical efficacy of combination therapy with ME3738 and pegylated interferon-alpha-2a in patients with hepatitis C virus genotype 1.

scientific article published on 20 June 2013

Clinical features and predictive value of serum inflammatory markers of perivascular involvement in immunoglobulin G4-related disease

scientific article published on 4 May 2017

Clinical features and prognosis in patients with hepatocellular carcinoma that developed after hepatitis C virus eradication with interferon therapy

scientific article published on 4 March 2011

Clinical features and prognosis of patients with extrahepatic metastases from hepatocellular carcinoma

scientific article

Clinical features of hepatocellular carcinoma in nonalcoholic fatty liver disease patients without advanced fibrosis

scientific article published on 06 March 2019

Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection

scientific article published on 27 September 2012

Clinical impact and characteristics of the narrow-band imaging magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team.

scientific article published on 25 July 2016

Clinical impact of dual red imaging in colorectal endoscopic submucosal dissection: a pilot study

scientific article

Clinical impact of surveillance colonoscopy using magnification without diminutive polyp removal.

scientific article published on 28 March 2017

Clinical impact of tumor invasion depth staging of esophageal squamous cell carcinoma using endoscopic ultrasonography

scientific article published on November 1, 2010

Clinical outcome and prognostic factors in hepatocellular carcinoma patients with bone metastases medicated with zoledronic acid

scientific article published on 15 November 2016

Clinical outcome and prognostic factors of patients with hepatocellular carcinoma and extrahepatic metastasis treated with sorafenib

scientific article published on 24 April 2014

Clinical outcome of esophageal varices after hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with major portal vein tumor thrombus

scientific article published on 01 November 2011

Clinical outcome of sorafenib treatment in patients with advanced hepatocellular carcinoma refractory to hepatic arterial infusion chemotherapy

scientific article published in December 2013

Clinical outcomes of endoscopic resection for superficial non-ampullary duodenal tumors

scientific article published on 21 February 2020

Clinical outcomes of endoscopic submucosal dissection and endoscopic mucosal resection for laterally spreading tumors larger than 20 mm

scientific article published on 01 April 2012

Clinical outcomes of endoscopic submucosal dissection for colorectal tumors: a large multicenter retrospective study from the Hiroshima GI Endoscopy Research Group.

scientific article published on 13 June 2017

Clinical outcomes of endoscopic submucosal dissection for early gastric cancer in patients with chronic kidney disease.

scientific article published in October 2013

Clinical outcomes of endoscopic submucosal dissection for rectal tumor close to the dentate line

scientific article published on 01 August 2012

Clinical outcomes of endoscopic submucosal dissection for superficial Barrett's adenocarcinoma

scientific article published on 22 February 2014

Clinical outcomes of sorafenib treatment failure for advanced hepatocellular carcinoma and candidates for regorafenib treatment in real-world practice

scientific article published on 27 May 2018

Clinical outcomes of stereotactic body radiotherapy for elderly patients with hepatocellular carcinoma

scientific article published on 24 June 2017

Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review

scientific article published on April 2009

Clinical significance and validity of the subclassification for colorectal laterally spreading tumor granular type

scientific article published on 25 November 2015

Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types.

scientific article published on October 2003

Clinical significance of angiogenesis in rectal carcinoid tumors

scientific article published on 01 May 2002

Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma

scientific article published in January 2003

Clinical significance of angiopoietin-2 expression at the deepest invasive tumor site of advanced colorectal carcinoma

scientific article published on 01 March 2004

Clinical significance of endoscopic ultrasonography in diagnosing invasion depth of early gastric cancer prior to endoscopic submucosal dissection

scientific article published on 22 June 2020

Clinical significance of immunohistochemical lymphovascular evaluation to determine additional surgery after endoscopic submucosal dissection for colorectal T1 carcinoma

scientific article published on 04 November 2020

Clinical significance of mucosal suppressors of cytokine signaling 3 expression in ulcerative colitis

scientific article

Clinical significance of small-bowel villous edema in patients with liver cirrhosis-a capsule endoscopy study

scientific article

Clinical significance of thrombospondin-1 expression in relation to vascular endothelial growth factor and interleukin-10 expression at the deepest invasive tumor site of advanced colorectal carcinoma

scientific article published on 01 October 2003

Clinical significance of type V(I) pit pattern subclassification in determining the depth of invasion of colorectal neoplasms

scientific article published on January 2008

Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma

scientific article published on 01 January 2002

Clinical usefulness of a single-use splinting tube for poor endoscope operability in deep colonic endoscopic submucosal dissection

scientific article published on 15 April 2016

Clinical usefulness of classification by transabdominal ultrasonography for detection of small-bowel stricture

scientific article published on 02 August 2013

Clinical usefulness of endocytoscopy in the remission stage of ulcerative colitis: a pilot study

scientific article

Clinical usefulness of magnifying endoscopy for non-ampullary duodenal tumors

scientific article published on April 2017

Clinical usefulness of narrow band imaging magnifying classification for colorectal tumors based on both surface pattern and microvessel features

scientific article published on May 2011

Clinical usefulness of narrow band imaging magnifying colonoscopy for assessing ulcerative colitis-associated cancer/dysplasia

scientific article

Clinical usefulness of the S-O clip during colorectal endoscopic submucosal dissection in difficult-to-access submucosal layer

scientific article published on 21 February 2020

Clinical usefulness of transabdominal ultrasonography prior to patency capsule for suspected small-bowel strictures

scientific article published on 14 October 2015

Clinical utility of gadoxetate disodium-enhanced hepatic MRI for stereotactic body radiotherapy of hepatocellular carcinoma

scientific article published on 31 July 2015

Clinical validity of endoscopic submucosal dissection for submucosal invasive gastric cancer: a single-center study

scientific article published on 23 July 2011

Clinical validity of the expanded criteria for endoscopic resection of undifferentiated-type early gastric cancer based on long-term outcomes

scientific article published on 11 October 2013

Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types

scientific article published on 01 February 2004

Clinicopathologic and endoscopic features of early-stage colorectal serrated adenocarcinoma

scientific article published on 12 December 2017

Clinicopathologic and genetic characteristics of gastric cancer in young male and female patients.

scientific article published in July 2006

Clinicopathologic features and endoscopic resection of early primary nonampullary duodenal carcinoma

scientific article

Clinicopathologic features of hyperplastic/serrated polyposis syndrome in Japan

scientific article published in November 2013

Clinicopathological features of elderly patients with hepatitis C virus-related hepatocellular carcinoma

scientific article published on 23 July 2008

Coffee with a high content of chlorogenic acids and low content of hydroxyhydroquinone improves postprandial endothelial dysfunction in patients with borderline and stage 1 hypertension

scientific article published on 12 January 2018

Colorectal endoscopic submucosal dissection: present status and future perspective, including its differentiation from endoscopic mucosal resection

scientific article published on 20 September 2008

Combination of Flow-Mediated Vasodilation and Nitroglycerine-Induced Vasodilation Is More Effective for Prediction of Cardiovascular Events.

scientific article published on 14 March 2016

Combination of hepatitis B viral antigens and DNA for prediction of relapse after discontinuation of nucleos(t)ide analogs in patients with chronic hepatitis B.

scientific article published on 22 November 2011

Combination of transcatheter arterial chemoembolization using cisplatin-lipiodol suspension and percutaneous ethanol injection for treatment of advanced small hepatocellular carcinoma

scientific article published in September 2002

Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice

scientific article published on 15 January 2013

Combination therapies with daclatasvir and asunaprevir on NS3-D168 mutated HCV in human hepatocyte chimeric mice.

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Combination therapy of low-dose medroxyprogesterone acetate and oral estrogen does not affect endothelial function in the forearms of postmenopausal women

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Combination therapy of oral fluoropyrimidine anticancer drug S-1 and interferon alpha for HCC patients with extrahepatic metastases

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Combinational use of hepatitis B viral antigens predicts responses to nucleos(t)ide analogue/peg-interferon sequential therapy.

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Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of HCV-infected Cells and Liver to Identify Pathways Associated With Disease Development

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Combining molecular targeted drugs to inhibit both cancer cells and activated stromal cells in gastric cancer

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Common Variant Near HEY2 Has a Protective Effect on Ventricular Fibrillation Occurrence in Brugada Syndrome by Regulating the Repolarization Current

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Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.

scientific article published in June 2011

Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.

scientific article published on 31 May 2010

Comparative study of 4 Fr versus 6 Fr nasobiliary drainage catheters: a randomized, controlled trial

Comparative study on the replication of HCV1b genome between wild-type and cell culture-adaptive mutant in regard to sensitivities against anti-HCV drugs

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Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy Combined with Radiotherapy and Sorafenib for Advanced Hepatocellular Carcinoma Patients with Major Portal Vein Tumor Thrombosis

scientific article published on 9 February 2018

Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy and Sorafenib in Patients with Hepatocellular Carcinoma Refractory to Transcatheter Arterial Chemoembolization

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Comparison of Stereotactic Body Radiation Therapy Combined With or Without Transcatheter Arterial Chemoembolization for Patients With Small Hepatocellular Carcinoma Ineligible for Resection or Ablation Therapies

scientific article published on 01 January 2018

Comparison of clinical outcome of hepatic arterial infusion chemotherapy and sorafenib for advanced hepatocellular carcinoma according to macrovascular invasion and transcatheter arterial chemoembolization refractory status

scientific article published on 10 May 2018

Comparison of detectability of small-bowel lesions between capsule endoscopy and double-balloon endoscopy for patients with suspected small-bowel disease

scientific article published on 10 January 2009

Comparison of forearm endothelial function between premenopausal and postmenopausal women with or without hypercholesterolemia

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Comparison of hepatic arterial infusion chemotherapy between 5-fluorouracil-based continuous infusion chemotherapy and low-dose cisplatin monotherapy for advanced hepatocellular carcinoma

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Comparison of hepatic arterial infusion chemotherapy versus sorafenib monotherapy in patients with advanced hepatocellular carcinoma

scientific article published in September 2015

Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice

scientific article published on 21 February 2019

Comparison of liver disease state progression in patients with eradication of versus persistent infection with hepatitis C virus: Markov chain analysis

scientific article published on 20 November 2020

Comparison of small-bowel mucosal injury between low-dose aspirin and non-aspirin non-steroidal anti-inflammatory drugs: a capsule endoscopy study

scientific article published on 22 May 2014

Complete response to pembrolizumab in advanced hepatocellular carcinoma with microsatellite instability

scientific article published on 04 February 2020

Complete response to short-term sorafenib treatment alone for hepatocellular carcinoma with bone, lymph node, and peritoneum metastases

scientific article published on 30 April 2016

Compliance with standard precautions among gastrointestinal endoscopists and endoscopy nurses in Japan

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Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area

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Computer-aided diagnosis of colorectal polyp histology by using a real-time image recognition system and narrow-band imaging magnifying colonoscopy

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Computer-aided system for predicting the histology of colorectal tumors by using narrow-band imaging magnifying colonoscopy (with video).

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Concise prediction models of anticancer efficacy of 8 drugs using expression data from 12 selected genes

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Condition of muscularis mucosae is a risk factor for lymph node metastasis in T1 colorectal carcinoma

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Construction of a risk model for the development of metachronous squamous cell carcinoma after endoscopic resection of esopahageal squamous cell carcinoma

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Continued use of low-dose aspirin does not increase the risk of bleeding during or after endoscopic submucosal dissection for early gastric cancer

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Coronary vasospasm produces reversible perfusion defects observed during adenosine triphosphate stress myocardial single-photon emission computed tomography

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Correction to: Efficacy and safety of glecaprevir/pibrentasvir in HCV-infected Japanese patients with prior DAA experience, severe renal impairment, or genotype 3 infection

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Correction to: Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradication therapy

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Correction to: The novel cutoff points for the FIB4 index categorized by age increase the diagnostic accuracy in NAFLD: a multi-center study

scientific article published on 01 November 2018

Correction: Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers

Correction: Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study

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Correlation between Early Tumor Marker Response and Imaging Response in Patients with Advanced Hepatocellular Carcinoma Treated with Lenvatinib

scientific article published on 26 June 2019

Correlation between efficacy of daclatasvir/asunaprevir combination therapy and HCV NS3/NS5A resistance-associated variants detected by the PCR-Invader assay

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Cost-effectiveness analyses of anti-HCV treatments using QOL scoring among patients with chronic liver disease in the Hiroshima prefecture.

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Critical role of exogenous nitric oxide in ROCK activity in vascular smooth muscle cells

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Cross-over study in hyperammonemia patients for efficacy, safety, and acceptability of a new lactulose preparation (SK-1202) compared to approved drug

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Culture density contributes to hepatic functions of fresh human hepatocytes isolated from chimeric mice with humanized livers: Novel, long-term, functional two-dimensional in vitro tool for developing new drugs

scientific article published on 11 September 2020

Current Status of Narrow-Band Imaging Magnifying Colonoscopy for Colorectal Neoplasia in Japan ⬇️

scientific article published on January 21, 2011

Current status and future perspectives of endoscopic submucosal dissection for colorectal tumors

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Current treatment for chronic hepatitis B in Japan

scientific article published on 28 July 2009

Cutaneous complications after transcatheter arterial treatment for hepatocellular carcinoma via the internal mammary artery: how to avoid this complication

scientific article published on 30 June 2011

Cytoprotective effect of tauroursodeoxycholate on hepatocyte apoptosis induced by peroxisome proliferator-activated receptor gamma ligand

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Daclatasvir and asunaprevir in hemodialysis patients with hepatitis C virus infection: a nationwide retrospective study in Japan

scientific article published on 30 May 2017

Daclatasvir and asunaprevir treatment improves liver function parameters and reduces liver fibrosis markers in chronic hepatitis C patients

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Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection

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Daclatasvir/asunaprevir/beclabuvir fixed-dose combination in Japanese patients with HCV genotype 1 infection

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Decrease in fasting insulin secretory function correlates with significant liver fibrosis in Japanese non-alcoholic fatty liver disease patients

scientific article published on 09 June 2020

Decreased frequency and duration of tooth brushing is a risk factor for endothelial dysfunction

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Defensive medicine practices among gastroenterologists in Japan

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Deletion of angiotensin II type I receptor reduces hepatic steatosis

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Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach.

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Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice

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Depressed-type, early duodenal carcinoma (carcinoma in situ) treated by endoscopic mucosal resection

scientific article published on 01 January 2003

Detectability and clinical significance of serum hepatitis B virus ribonucleic acid

scientific article published on June 2015

Detection of Hantaviral Antibodies among Patients with Hepatitis of Unknown Etiology in Japan

scientific article published in 2000

Detection of Helicobacter hepaticus in human bile samples of patients with biliary disease

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Detection of acute toxicity of aflatoxin B1 to human hepatocytes in vitro and in vivo using chimeric mice with humanized livers

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Detection of hepatitis C virus RNA

scientific article published in July 2004

Detection of nonpolypoid colorectal neoplasia using magnifying endoscopy in colonic inflammatory bowel disease

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Determining depth of invasion by VN pit pattern analysis in submucosal colorectal carcinoma

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Development of a Novel Site-Specific Pegylated Interferon Beta for Antiviral Therapy of Chronic Hepatitis B Virus

scientific article published on 3 April 2017

Development of a novel method to detect Helicobacter pylori cagA genotype from paraffin-embedded materials: comparison between patients with duodenal ulcer and gastric cancer in young Japanese

scientific article published on 14 March 2006

Development of hepatocellular carcinoma in patients with hepatitis C virus infection who achieved sustained virological response following interferon therapy: A large-scale, long-term cohort study.

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Development of new therapies using an animal model of hepatitis virus infection

scientific article published on December 2015

Diagnosis of Helicobacter pylori-induced gastritis by serum pepsinogen levels

scientific article published on 14 May 2015

Diagnostic Criteria of Flow-Mediated Vasodilation for Normal Endothelial Function and Nitroglycerin-Induced Vasodilation for Normal Vascular Smooth Muscle Function of the Brachial Artery

scientific article published on 08 January 2020

Diagnostic Yield of Colon Capsule Endoscopy in Detection of Superficial Colorectal Lesions

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Diagnostic performance of Japan NBI Expert Team classification for differentiation among noninvasive, superficially invasive, and deeply invasive colorectal neoplasia

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Diagnostic yield of capsule endoscopy vs. double-balloon endoscopy for patients who have undergone total enteroscopy with obscure gastrointestinal bleeding.

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Differences in K-ras and mitochondrial DNA mutations and microsatellite instability between colorectal cancers of Vietnamese and Japanese patients.

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Differences in characteristics of glucose intolerance between patients with NAFLD and chronic hepatitis C as determined by CGMS

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Differences in serum microRNA profiles in hepatitis B and C virus infection.

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Different role of macrophages and vascular smooth muscle cells in atherosclerotic lesions of Watanabe heritable hyperlipidemic (WHHL) rabbit between aorta and coronary artery

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Differential effects of interferon and lamivudine on serum HBV RNA inhibition in patients with chronic hepatitis B.

scientific article published in January 2010

Diminished hepatic IFN response following HCV clearance triggers HBV reactivation in coinfection

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Direct-acting antiviral-resistant variant

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Discordant pathological diagnosis of non-alcoholic fatty liver disease: A prospective multicenter study

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Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients ⬇️

scientific article published on June 1, 1998

Disruption of the type 2 dopamine receptor gene causes a sodium-dependent increase in blood pressure in mice

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Disseminated carcinomatosis of the bone marrow originating from hepatocellular carcinoma. A case report

scientific article published on 3 September 2014

Does intragastric nitrite concentration reflect gastric carcinogenesis in Japanese Helicobacter pylori-infected patients?

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Dose comparison study of pegylated interferon-alpha-2b plus ribavirin in naïve Japanese patients with hepatitis C virus genotype 2: a randomized clinical trial

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Double-balloon enteroscopy in patients with GI bleeding of obscure origin

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Dual Red Imaging Maintains Clear Visibility During Colorectal Endoscopic Submucosal Dissection

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Dual effect of APOBEC3G on Hepatitis B virus

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Dual oral therapy with daclatasvir and asunaprevir for patients with HCV genotype 1b infection and limited treatment options

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Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders

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Dynamic computed tomography appearance of tumor response after stereotactic body radiation therapy for hepatocellular carcinoma: How should we evaluate treatment effects?

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Early Multiphasic HBV Infection Initiation Kinetics Is Not Clone-Specific and Is Not Affected by Hepatitis D Virus (HDV) Infection

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Early changes in ammonia levels and liver function in patients with advanced hepatocellular carcinoma treated by lenvatinib therapy

scientific article published on 20 August 2019

Early events in hepatitis B virus infection: From the cell surface to the nucleus

scientific article published on 28 September 2015

Early experience of seven hepatocellular carcinoma cases treated with regorafenib

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Early squamous cell carcinoma of the anal canal resected by endoscopic submucosal dissection

scientific article published on January 2015

Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes

scientific article published on 20 February 2019

Earthworm fibrinolytic enzyme: anti-tumor activity on human hepatoma cells in vitro and in vivo.

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Ecabet sodium induces neuronal nitric oxide synthase-derived nitric oxide synthesis and gastric adaptive relaxation in the human stomach

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Edaravone (3-Methyl-1-Phenyl-2-Pyrazolin-5-one), A Novel Free Radical Scavenger, for Treatment of Cardiovascular Diseases

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Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study

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Effect of alcohol consumption on endothelial function in men with coronary artery disease

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Effect of aldosterone-producing adenoma on endothelial function and Rho-associated kinase activity in patients with primary aldosteronism.

scientific article published on 26 January 2015

Effect of arterial administration of a high molecular weight anti-tumor agent, styrene maleic acid neocarzinostatin, for multiple small liver cancer—A pilot study ⬇️

scientific article published on August 1, 1997

Effect of different intensities of exercise on endothelium-dependent vasodilation in humans: role of endothelium-dependent nitric oxide and oxidative stress

scientific article published on 21 July 2003

Effect of edaravone, a novel free radical scavenger, on endothelium-dependent vasodilation in smokers

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Effect of interferon therapy on viral titers in patients with chronic hepatitis C who are positive for hepatitis GB virus C ⬇️

scientific article published on October 1, 1997

Effect of obesity on endothelium-dependent, nitric oxide–mediated vasodilation in normotensive individuals and patients with essential hypertension ⬇️

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Effect of prolonged administration of pegylated interferon/ribavirin therapy in genotypes 2a and 2b: propensity score-matched analysis

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Effect of tenofovir disoproxil fumarate on drug-resistant HBV clones

scientific article published on 26 October 2015

Effect of urine pH changed by dietary intervention on uric acid clearance mechanism of pH-dependent excretion of urinary uric acid ⬇️

scientific article published on June 7, 2012

Effectiveness of polaprezinc for low-dose aspirin-induced small-bowel mucosal injuries as evaluated by capsule endoscopy: a pilot randomized controlled study.

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Effectiveness of prokinetic agents against diseases external to the gastrointestinal tract

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Effects of ITPA polymorphism on decrease of hemoglobin during simeprevir, peg-interferon, and ribavirin combination treatment for chronic hepatitis C.

scientific article published on 25 February 2016

Effects of a 24-week course of interferon-alpha therapy after curative treatment of hepatitis C virus-associated hepatocellular carcinoma

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Effects of acute administration of caffeine on vascular function

scientific article published on 16 October 2006

Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study

Effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway.

scientific article published on March 2015

Effects of hepatitis B virus infection on the interferon response in immunodeficient human hepatocyte chimeric mice

scientific article published in July 2011

Effects of structural variations of APOBEC3A and APOBEC3B genes in chronic hepatitis B virus infection

scientific article published on 25 September 2009

Effects of the Dipeptidyl Peptidase 4 Inhibitor Alogliptin on Blood Pressure in Hypertensive Patients with Type 2 Diabetes Mellitus

scientific article published on 01 June 2019

Efficacy and Safety of Glecaprevir/Pibrentasvir in Japanese Patients with Chronic Genotype 2 Hepatitis C Virus Infection.

scientific article published on 2 September 2017

Efficacy and safety of daclatasvir plus asunaprevir therapy for chronic hepatitis C patients with renal dysfunction.

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Efficacy and safety of edoxaban for treatment of portal vein thrombosis following danaparoid sodium in patients with liver cirrhosis

scientific article published on 24 March 2017

Efficacy and safety of glecaprevir/pibrentasvir in HCV-infected Japanese patients with prior DAA experience, severe renal impairment, or genotype 3 infection

scientific article published on 20 October 2017

Efficacy and safety of glecaprevir/pibrentasvir in Japanese patients with chronic genotype 1 hepatitis C virus infection with and without cirrhosis.

scientific article published on 25 September 2017

Efficacy and safety of ledipasvir/sofosbuvir with ribavirin in chronic hepatitis C patients who failed daclatasvir/asunaprevir therapy: pilot study

scientific article published on 16 August 2017

Efficacy and safety of sitagliptin for the treatment of nonalcoholic fatty liver disease with type 2 diabetes mellitus

scientific article published in March 2014

Efficacy and safety of sofosbuvir-velpatasvir with or without ribavirin in HCV-infected Japanese patients with decompensated cirrhosis: an open-label phase 3 trial

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Efficacy and safety of telaprevir with natural human interferon-β and ribavirin in Japanese chronic hepatitis C patients with depression

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Efficacy and safety of telaprevir, a new protease inhibitor, for difficult‐to‐treat patients with genotype 1 chronic hepatitis C ⬇️

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Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis

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Efficacy of Lusutrombopag for Thrombocytopenia in Patients with Chronic Liver Disease Scheduled to Undergo Invasive Procedures

scientific article published on 21 October 2020

Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia

scientific article published in December 2008

Efficacy of ecabet sodium enema on intractable rectal ulcer after piecemeal endoscopic mucosal resection for rectal tumor

scientific article published on 17 September 2010

Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice

scientific article published on 14 June 2019

Efficacy of percutaneous cementoplasty for bone metastasis from hepatocellular carcinoma

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Efficacy of probucol for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label pilot study

scientific article published on 15 May 2013

Efficacy of radiofrequency ablation for initial recurrent hepatocellular carcinoma after curative treatment: Comparison with primary cases

scientific article published on 28 April 2015

Efficacy of rosuvastatin for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label, pilot study

scientific article published on 14 May 2012

Efficacy of telaprevir-based therapy for difficult-to-treat patients with genotype 2 chronic hepatitis C in Japan

scientific article published on 18 November 2014

Eicosapentaenoic acid could permit maintenance of the original ribavirin dose in chronic hepatitis C virus patients during the first 12 weeks of combination therapy with pegylated interferon-alpha and ribavirin. A prospective randomized controlled t

scientific article published in January 2007

Eicosapentaenoic acid/arachidonic acid ratio as a possible link between non-alcoholic fatty liver disease and cardiovascular disease

scientific article published on 18 July 2014

Elevated expression of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 in primary sclerosing cholangitis: ιmplications for cholangiocarcinogenesis

scientific article published on 24 July 2013

Elevated levels of serum advanced glycation end products in patients with non-alcoholic steatohepatitis

scientific article published on 07 June 2007

Elevation of Serum Levels of Advanced Glycation End Products in Patients With Non-B or Non-C Hepatocellular Carcinoma.

scientific article published on 23 September 2014

Elimination of HCV via a non-ISG-mediated mechanism by vaniprevir and BMS-788329 combination therapy in human hepatocyte chimeric mice

scientific article published on 10 November 2015

Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice

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Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif.

scientific article published on 18 September 2006

Emergence of drug resistance-associated variants and changes in serum lipid profiles in sofosbuvir plus ledipasvir-treated chronic hepatitis C patients.

scientific article published on 28 June 2017

Emerging treatments for chronic hepatitis C.

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Endocannabinoid CB1 antagonists inhibit hepatitis C virus production, providing a novel class of antiviral host-targeting agents

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Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes

scientific article published on 18 September 2018

Endoscopic assessment of colorectal cancer with superficial or deep submucosal invasion using magnifying colonoscopy

scientific article published on 31 March 2013

Endoscopic features and management of diminutive colorectal submucosal invasive carcinoma

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Endoscopic findings of the gastric mucosa during long-term use of proton pump inhibitor - a multicenter study

scientific article published on 9 May 2017

Endoscopic submucosal dissection as total excisional biopsy for clinical T1 colorectal carcinoma

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Endoscopic submucosal dissection for anorectal tumor with hemorrhoids close to the dentate line: a multicenter study of Hiroshima GI Endoscopy Study Group

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Endoscopic submucosal dissection for colorectal neoplasia: possibility of standardization

scientific article published on July 2007

Endoscopic submucosal dissection for residual early gastric cancer after endoscopic submucosal dissection

scientific article published in December 2012

Endothelial Dysfunction, Increased Arterial Stiffness, and Cardiovascular Risk Prediction in Patients With Coronary Artery Disease: FMD-J (Flow-Mediated Dilation Japan) Study A

scientific article published on 12 July 2018

Endothelial Function Assessed by Automatic Measurement of Enclosed Zone Flow-Mediated Vasodilation Using an Oscillometric Method Is an Independent Predictor of Cardiovascular Events.

scientific article published on 21 December 2016

Endothelial Function Is Impaired in Patients Receiving Antihypertensive Drug Treatment Regardless of Blood Pressure Level: FMD-J Study (Flow-Mediated Dilation Japan).

scientific article published on 14 August 2017

Endothelial dysfunction and abnormal vascular structure are simultaneously present in patients with heart failure with preserved ejection fraction

scientific article published on 05 January 2017

Endothelial dysfunction is an independent factor responsible for vasospastic angina ⬇️

scientific article published on December 1, 2001

Endothelial dysfunction, abnormal vascular structure and lower urinary tract symptoms in men and women

scientific article published on 01 June 2018

Endothelial function and oxidative stress in renovascular hypertension

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Endothelial function in subjects with isolated low HDL cholesterol: role of nitric oxide and circulating progenitor cells

scientific article published on 10 November 2009

Endothelial function is impaired in relation to alcohol intake even in the case of light alcohol consumption in Asian men; Flow-mediated Dilation Japan (FMD-J) Study.

scientific article published on 21 December 2016

Epidemiological survey of hemoglobin A1c and liver fibrosis in a general population with non-alcoholic fatty liver disease

scientific article published on 28 November 2018

Epigenetic inactivation of SOCS-1 by CpG island hypermethylation in human gastric carcinoma

scientific article published on 01 December 2004

Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study

Eradication of hepatitis C virus genotype 1 after liver transplantation by interferon therapy before surgery: Report of three patients with analysis of interleukin-28 polymorphism, hepatitis C virus core region and interferon-sensitivity determining

scientific article published in November 2011

Erratum to: Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy

scientific article published in January 2018

Establishment of a novel hepatitis B virus culture system using immortalized human hepatocytes

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Establishment of an infectious genotype 1b hepatitis C virus clone in human hepatocyte chimeric mice

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Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development

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Estrogen replacement suppresses function of thrombin stimulated platelets by inhibiting Ca(2+) influx and raising cyclic adenosine monophosphate

scientific article published in February 2002

Etiology and outcome of acute liver failure: retrospective analysis of 50 patients treated at a single center

scientific article published on 10 July 2008

Evaluation and validation of computed virtual chromoendoscopy in early gastric cancer

scientific article published on 18 January 2009

Evaluation for the Clinical Efficacy of Colon Capsule Endoscopy in the Detection of Laterally Spreading Tumors

scientific article published on 5 January 2017

Evaluation of antibiotic use to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis and cholangitis

scientific article published in March 2015

Evaluation of antiviral effect of type I, II, and III interferons on direct-acting antiviral-resistant hepatitis C virus

scientific article published on 29 August 2017

Evaluation of colon cancer vascularity by flash echo imaging

scientific article published on 01 January 2008

Evaluation of dual-wavelength excitation autofluorescence imaging of colorectal tumours with a high-sensitivity CMOS imager: a cross-sectional study.

scientific article published on 2 September 2015

Evaluation of early response to hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma using the combination of response evaluation criteria in solid tumors and tumor markers

scientific article published on 01 April 2015

Evaluation of endoscopic and histological findings in Helicobacter pylori-positive Japanese young adults

scientific article

Evaluation of gastric cancer risk using topography of histological gastritis: a large-scaled cross-sectional study

scientific article published on 13 November 2007

Evaluation of glycemic variability in chronic liver disease patients with type 2 diabetes mellitus using continuous glucose monitoring

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Evaluation of individual risk in nonvariceal gastrointestinal bleeding patients with NSAID administration: a multicenter study in Japan

scientific article published on 17 August 2012

Evaluation of long-term entecavir treatment in stable chronic hepatitis B patients switched from lamivudine therapy

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Evaluation of microvessels in colorectal tumors by narrow band imaging magnification

scientific article published in November 2007

Evaluation of patients with esophageal varices after endoscopic injection sclerotherapy using multiplanar reconstruction MDCT images

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Evaluation of portosystemic collaterals by MDCT-MPR imaging for management of hemorrhagic esophageal varices

scientific article published on 14 July 2009

Evaluation of the mRECIST and α-fetoprotein ratio for stratification of the prognosis of advanced-hepatocellular-carcinoma patients treated with sorafenib

scientific article published on 11 August 2012

Evaluation of the visibility of early gastric cancer using linked color imaging and blue laser imaging

scientific article published on 8 December 2017

Evolution of hepatitis C virus quasispecies during ribavirin and interferon-alpha-2b combination therapy and interferon-alpha-2b monotherapy

scientific article published on 21 August 2006

Exacerbation of Portal Hypertensive Enteropathy after Endoscopic Injection Sclerotherapy for Esophageal Varices

scientific article published on 01 October 2019

Excess norepinephrine impairs both endothelium-dependent and -independent vasodilation in patients with pheochromocytoma

scientific article published in February 2002

Experience with Balloon Dilatation in Crohn's and Non-Crohn's Benign Small-Bowel Strictures: Is There a Difference?

scientific article published on 6 May 2019

Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma

scientific article published on January 2004

Expression of fibroblast growth factor receptor genes in human hepatoma-derived cell lines

scientific article published on July 2003

Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions

scientific article published on January 2004

Expression of hypoxia-inducible factor (HIF)-1alpha is associated with vascular endothelial growth factor expression and tumour angiogenesis in human oesophageal squamous cell carcinoma

scientific article published on August 2004

Expression of hypoxia-inducible factor-1alpha is associated with tumor vascularization in human colorectal carcinoma.

scientific article published on June 2003

Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer.

scientific article

Expression of p53 protein in esophageal squamous cell carcinoma: relation to hypoxia-inducible factor-1alpha, angiogenesis and apoptosis

scientific article published on January 2005

Expression of platelet-derived growth factor (PDGF)-B and PDGF-receptor β is associated with lymphatic metastasis in human gastric carcinoma

scientific article published on September 2010

Expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in early gastric carcinoma: correlation with clinicopathological parameters

scientific article published on August 2005

Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach

scientific article published on 01 January 2003

Expressions of angiogenic factors in pancreatic ductal carcinoma: a correlative study with clinicopathologic parameters and patient survival

scientific article published in May 2003

Extracellular water to total body water ratio obtained by bioelectrical impedance analysis determines the dose intensity of lenvatinib for the treatment of patients with advanced hepatocellular carcinoma

scientific article published on 16 December 2020

Extracorporeal Ultrasound is an Effective Diagnostic Alternative to Endoscopic Ultrasound for Gastric Submucosal Tumours ⬇️

scientific article published on 01 November 2001

FDG positron emission tomography/computed tomography for the detection of extrahepatic metastases from hepatocellular carcinoma

scientific article published on 01 February 2009

Factors associated with the effect of interferon-α sequential therapy in order to discontinue nucleoside/nucleotide analog treatment in patients with chronic hepatitis B.

scientific article published on 15 January 2015

Factors predictive of sustained virological response following 72 weeks of combination therapy for genotype 1b hepatitis C.

scientific article published on 19 January 2011

Fas and Fas ligand: Expression and soluble circulating levels in bile duct carcinoma.

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Feasibility of Freeze-Dried Sera for Serological and Molecular Biological Detection of Hepatitis B and C Viruses

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Flow-mediated vasodilation and anatomical variation of the brachial artery (double brachial artery) in healthy subjects and patients with cardiovascular disease

scientific article published on 7 December 2012

Flow-mediated vasodilation is augmented in a corkscrew collateral artery compared with that in a native artery in patients with thromboangiitis obliterans (Buerger disease)

scientific article published on 09 September 2011

Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion

scientific article published on 31 August 2020

Follow up of the 987 blood donors found with hepatitis C virus infection over 9-18 years

scientific article published on 8 March 2012

Food deprivation enhances somatostatin and somatostatin receptor subtype expression in rat colon

scientific article published in July 2003

Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma

scientific article published on June 2004

Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma

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Frequent loss of heterozygosity on chromosome 10p14-p15 in esophageal dysplasia and squamous cell carcinoma.

scientific article

Frequent loss of heterozygosity on chromosome 10p15, a putative telomerase repressor/senescence gene locus, in gastric cancer.

scientific article published in September 2003

Frequent somatic mutations of mitochondrial DNA in traditional serrated adenomas but not in sessile serrated adenomas of the colorectum

scientific article published in October 2011

Functional Behavior of NKp46-Positive Intrahepatic Natural Killer Cells Against Hepatitis C Virus Reinfection After Liver Transplantation

scientific article published on 28 December 2015

Future perspectives of treatment of chronic hepatitis C.

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G to A hypermutation of TT virus.

scientific article published on 6 February 2010

G to A hypermutation of hepatitis B virus.

scientific article published on March 2005

G-to-A hypermutation in hepatitis B virus (HBV) and clinical course of patients with chronic HBV infection

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GJA1 gene polymorphism is a genetic predictor of recurrence following pulmonary vein isolation in patients with paroxysmal atrial fibrillation

scientific article published in 2022

Gastric Cancer with Submucosal Invasion after Successful Helicobacter pylori Eradication: A Propensity Score-Matched Analysis of Patients with Annual Patient Endoscopic Survey

scientific article published on 14 December 2018

Gastric cancer development after Helicobacter pylori eradication therapy: a new form of gastric neoplasia

scientific article published on 5 January 2012

Gastric juice nitrite and vitamin C in patients with gastric cancer and atrophic gastritis: is low acidity solely responsible for cancer risk?

scientific article published in September 2003

Gastrointestinal stromal tumor in jejunum: diagnosis using contrast-enhanced ultrasonography and double-balloon enteroscopy

scientific article published on 01 July 2006

Gemcitabine suppresses malignant ascites of human pancreatic cancer: correlation with VEGF expression in ascites

scientific article published on January 2004

Gene delivery of paraoxonase-1 inhibits neointimal hyperplasia after arterial balloon-injury in rabbits fed a high-fat diet

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Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development

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Genetic and pathologic characteristics of gastrointestinal stromal tumors in extragastric lesions.

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Genetic pathways of multiple esophageal squamous cell carcinomas

scientific article published on 14 December 2010

Genetic polymorphisms and esophageal cancer risk

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Genetic polymorphisms and head and neck cancer risk (Review).

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Genetic progression and divergence in superficial esophageal squamous cell carcinoma by loss of heterozygosity analysis

scientific article published on 01 October 2006

Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women.

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Genetic variations of aldehyde dehydrogenase 2 and alcohol dehydrogenase 1B are associated with the etiology of atrial fibrillation in Japanese

scientific article published on 7 December 2016

Genetics of IL28B and HCV--response to infection and treatment

scientific article published on 29 May 2012

Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population

scientific article published on 5 January 2017

Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan.

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Genomic Characterization of Biliary Tract Cancers Identifies Driver Genes and Predisposing Mutations.

scientific article published on 19 January 2018

Genomic Characterization of Non-Invasive Differentiated-Type Gastric Cancer in the Japanese Population

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Genomic Landscape of Early-stage Colorectal Neoplasia Developing From the Ulcerative Colitis Mucosa in the Japanese Population

scientific article published on 22 October 2020

Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes

scientific article published on 23 May 2019

Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population

scientific article published on 25 June 2019

Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy

scientific article published on 13 June 2019

Geranylgeranylacetone, heat shock protein 90/AMP-activated protein kinase/endothelial nitric oxide synthase/nitric oxide pathway, and endothelial function in humans

scientific article published on 13 October 2011

Giant gastric folds: differential diagnosis at US

scientific article published on 24 January 2003

Glycemic variability is an independent predictive factor for development of hepatic fibrosis in nonalcoholic fatty liver disease

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Glycochenodeoxycholate plays a carcinogenic role in immortalized mouse cholangiocytes via oxidative DNA damage

scientific article published on 11 August 2005

Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis B virus infection for the fiscal year 2008 in Japan

scientific article published in January 2010

Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis C virus infection for the fiscal year 2008 in Japan

scientific article published in January 2010

H558R, a common SCN5A polymorphism, modifies the clinical phenotype of Brugada syndrome by modulating DNA methylation of SCN5A promoters

scientific article published on 4 December 2017

HBV culture and infectious systems

scientific article published on 2 March 2016

HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice.

scientific article published on 10 March 2010

HCN4 Gene Polymorphisms Are Associated With Occurrence of Tachycardia-Induced Cardiomyopathy in Patients With Atrial Fibrillation

scientific article published on 01 July 2018

HCV Drug Resistance Challenges in Japan: The Role of Pre-Existing Variants and Emerging Resistant Strains in Direct Acting Antiviral Therapy

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HCV kinetic and modeling analyses project shorter durations to cure under combined therapy with daclatasvir and asunaprevir in chronic HCV-infected patients

scientific article published on 7 December 2017

HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy

scientific article published on 10 November 2010

HCV-HBV infection

scientific article published in July 2006

HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response

scientific article published on 02 March 2019

HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study

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HOMA-IR: An independent predictor of advanced liver fibrosis in nondiabetic non-alcoholic fatty liver disease

scientific article published on 03 February 2019

Helicobacter pylori cagA polymorphism and gastric inflammation: an international comparison between Japanese and Brazilian patients

scientific article published on 8 July 2011

Helicobacter pylori dupA and gastric acid secretion are negatively associated with gastric cancer development

scientific article published on 9 September 2010

Helicobacter pylori infection increases serum nitrate and nitrite more prominently than serum pepsinogens

scientific article published on 01 February 2002

Helicobacter pylori infection influences expression of genes related to angiogenesis and invasion in human gastric carcinoma cells

scientific article published on November 2003

Helicobacter pylori infection is the major risk factor for gastric inflammation in the cardia

scientific article published on 8 April 2006

Helicobacter suis infection is associated with nodular gastritis-like appearance of gastric mucosa-associated lymphoid tissue lymphoma

scientific article published on 18 June 2019

Hematocrit, hemoglobin and red blood cells are associated with vascular function and vascular structure in men

scientific article published on 10 July 2020

Hepatectomy after down-staging of hepatocellular carcinoma with portal vein tumor thrombus using chemoradiotherapy: A retrospective cohort study

scientific article published on 01 July 2017

Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity-matched analysis in a single institution

scientific article published on 23 May 2018

Hepatic Arterial Infusion Chemotherapy versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma

scientific article published on 24 July 2020

Hepatic arterial infusion chemotherapy followed by sorafenib in patients with advanced hepatocellular carcinoma (HICS 55): an open label, non-comparative, phase II trial.

scientific article published on 4 June 2018

Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma according to Child-Pugh classification

scientific article published on 01 December 2012

Hepatic arterial infusion chemotherapy using 5-fluorouracil and systemic interferon-α for advanced hepatocellular carcinoma in combination with or without three-dimensional conformal radiotherapy to venous tumor thrombosis in hepatic vein or inferio

scientific article published on 16 December 2011

Hepatic carcinosarcoma with heterogeneous carcinomatous and sarcomatous elements: report of a case and review of the literature

scientific article published on 25 February 2010

Hepatitis B virus evades innate immunity of hepatocytes but activates cytokine production by macrophages

scientific article published on 30 June 2017

Hepatitis B virus-specific miRNAs and Argonaute2 play a role in the viral life cycle

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Hepatitis C virus (HCV) reactivation caused by steroid therapy for dermatomyositis

scientific article published on December 2014

Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver

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Hepatitis C virus core protein suppresses mitophagy by interacting with parkin in the context of mitochondrial depolarization

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Hepatitis C virus infection suppresses the interferon response in the liver of the human hepatocyte chimeric mouse

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Hepatitis C virus: How genetic variability affects pathobiology of disease

scientific article published on January 2011

Hepatocellular carcinoma in Japanese patients with nonalcoholic fatty liver disease and alcoholic liver disease: multicenter survey

scientific article published on 11 October 2015

Hepatocellular carcinoma treated with sorafenib: Arterial tumor perfusion in dynamic contrast-enhanced CT as early imaging biomarkers for survival

scientific article published on 4 November 2017

Hepatocellular carcinoma: towards personalized medicine.

scientific article published on 15 March 2012

High expression of gastrin receptor protein in injured mucosa of Helicobacter pylori-positive gastritis

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High incidence of B-cell monoclonality in follicular gastritis: a possible association between follicular gastritis and MALT lymphoma

scientific article published on 26 January 2002

High-magnification colonoscopy (with videos).

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Highly multiplexed CRISPR-Cas9-nuclease and Cas9-nickase vectors for inactivation of hepatitis B virus

scientific article published on 23 September 2016

Hormone replacement effects on endothelial function measured in the forearm resistance artery in normocholesterolemic and hypercholesterolemic postmenopausal women

scientific article published in October 2002

Host factors contributing to the discovery of gastric cancer after successful eradication therapy of Helicobacter pylori: preliminary report

scientific article published in April 2007

Human Cytotoxic T Lymphocyte-Mediated Acute Liver Failure and Rescue by Immunoglobulin in Human Hepatocyte Transplant TK-NOG Mice

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Hydrophilic bile salts have a cytoprotective effect against cyclosporine A-induced cholestasis through enhanced canalicular membrane fluidity and transporter activity

scientific article published in January 2003

Hyperbilirubinemia, augmentation of endothelial function, and decrease in oxidative stress in Gilbert syndrome

scientific article published on 06 July 2012

Hypersensitivity reactions to transcatheter chemoembolization with cisplatin and Lipiodol suspension for unresectable hepatocellular carcinoma

scientific article published on 01 August 2010

Hyperuricemia is independently associated with endothelial dysfunction in postmenopausal women but not in premenopausal women

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Hypovascular hepatic nodules showing hypointense on the hepatobiliary-phase image of Gd-EOB-DTPA-enhanced MRI to develop a hypervascular hepatocellular carcinoma: a nationwide retrospective study on their natural course and risk factors

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Hypoxia-inducible factor-1alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach

scientific article published on 01 July 2003

IFNL4 polymorphism effects on outcome of simeprevir, peginterferon, and ribavirin therapy for older patients with genotype 1 chronic hepatitis C.

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IFNL4/IL-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population

scientific article published on 19 March 2014

IL-1β/ATF3-mediated induction of Ski2 expression enhances hepatitis B virus x mRNA degradation

scientific article published on 25 July 2018

IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.

scientific article published on 12 January 2011

IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones.

scientific article published on 25 August 2010

IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.

scientific article published on 4 February 2011

IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C

scientific article published in July 2011

IL28B polymorphism is associated with fatty change in the liver of chronic hepatitis C patients.

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ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.

scientific article published on 14 July 2010

ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C.

scientific article published on 7 November 2016

Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk.

scientific article published on 11 April 2013

Identification of novel HCV deletion mutants in chronic hepatitis C patients

scientific article published on 25 July 2012

Identification of rare polymerase variants of hepatitis B virus using a two-stage PCR with peptide nucleic acid clamping

scientific article published in April 2004

Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor

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Images in cardiovascular medicine. Corkscrew collaterals in thromboangitis obliterans (Buerger's disease)

scientific article published on 01 November 2007

Immune response in mouse experimental cholangitis associated with colitis induced by dextran sulfate sodium

scientific article published on 01 August 2004

Immune response to CagA protein is associated with improved platelet count after Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura

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Immunohistochemical molecular markers as predictors of curability of endoscopically resected submucosal colorectal cancer

scientific article published on July 2007

Impact of Hepatitis C Virus Eradication on the Clinical Outcome of Patients with Hepatitis C Virus-Related Advanced Hepatocellular Carcinoma Treated with Sorafenib

scientific article published on March 2017

Impact of alloimmune T cell responses on hepatitis C virus replication in liver transplant recipients

scientific article published on 7 October 2014

Impact of interleukin-28B genotype on in vitro and in vivo systems of hepatitis C virus replication

scientific article published on 23 April 2012

Impact of pegylated interferon therapy on outcomes of patients with hepatitis C virus-related hepatocellular carcinoma after curative hepatic resection

scientific article published on 28 June 2011

Impact of radiation and hepatitis virus infection on risk of hepatocellular carcinoma

scientific article published in April 2011

Impact of ribavirin dose reduction on the efficacy of pegylated interferon plus ribavirin combination therapy for elderly patients infected with genotype 1b and high viral loads

scientific article published in July 2011

Impact of sclerosing dacryoadenitis/sialadenitis on relapse during steroid therapy in patients with type 1 autoimmune pancreatitis

scientific article published on 01 February 2019

Impact of the introduction of direct-acting anti-viral drugs on hepatocarcinogenesis: a prospective serial follow-up MRI study

scientific article published on 10 June 2020

Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus

scientific article published on 2 August 2011

Impact of viral eradication by DAAs on the risk of HCC development, prognosis and portal hypertension in HCV-related compensated cirrhosis patients

scientific article published on 06 August 2020

Impaired coronary microvascular endothelial function in men with metabolic syndrome

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Impaired gallbladder mucosal function in aged gallstone patients suppresses gallstone recurrence after successful extracorporeal shockwave lithotripsy

scientific article published in February 2003

Impaired gastric response to modified sham feeding in patients with postprandial distress syndrome ⬇️

scientific article published on 09 November 2010

Impaired myocardial blood flow reserve in subjects with metabolic syndrome analyzed using positron emission tomography and N-13 labeled ammonia

scientific article published on 14 November 2009

Implication of anti-parietal cell antibody levels in gastrointestinal diseases, including gastric carcinogenesis

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Importance of serum concentration of adefovir for Lamivudine-adefovir combination therapy in patients with lamivudine-resistant chronic hepatitis B.

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Improved detectability of small-bowel lesions via capsule endoscopy with computed virtual chromoendoscopy: a pilot study

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Improved visibility of lesions of the small intestine via capsule endoscopy with computed virtual chromoendoscopy

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Improvement of atrial signal-averaged electrocardiographic abnormalities after radiofrequency catheter ablation in persistent atrial flutter

scientific article published on 01 September 2004

Improvement of renal dysfunction in a patient with hepatitis C virus-related liver cirrhosis by daclatasvir and asunaprevir combination therapy: A case report.

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In vivo adaptation of hepatitis C virus in chimpanzees for efficient virus production and evasion of apoptosis.

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In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors

scientific article published on 9 April 2018

Incidence of microsatellite instability-high hepatocellular carcinoma among Japanese patients and response to pembrolizumab

scientific article published on 23 February 2020

Increased arterial stiffness and cardiovascular risk prediction in controlled hypertensive patients with coronary artery disease: post hoc analysis of FMD-J (Flow-mediated Dilation Japan) Study A

scientific article published on 09 March 2020

Increased insulinogenic index is an independent determinant of nonalcoholic fatty liver disease activity score in patients with normal glucose tolerance

scientific article published on 17 July 2012

Increasing Risk of Osteoporotic Fracture Is Associated With Vascular Dysfunction and Abnormal Vascular Structure in Both Men and Women

scientific article published on 23 February 2017

Indication and Usefulness of Bile Juice Cytology for Diagnosis of Gallbladder Cancer.

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Indications for Small-bowel Capsule Endoscopy in Patients with Chronic Abdominal Pain

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Individual patient data meta-analysis of controlled attenuation parameter (CAP) technology for assessing steatosis

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Induction of apoptosis by ionizing radiation and CI-1033 in HuCCT-1 cells

scientific article published on June 2004

Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus

scientific article published on November 2005

Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon.

scientific article published on 20 April 2007

Inferior vena cava tumor thrombus that directly infiltrated from paracaval lymph node metastases in a patient with recurrent hepatocellular carcinoma

scientific article published on 6 August 2013

Infliximab therapy for Crohn's disease in a patient with chronic hepatitis B.

scientific article published in January 2005

Infliximab treatment for Crohn's disease in a patient with IgA nephropathy

scientific article published on 03 October 2009

Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.

scientific article published on 18 January 2011

Influence of the rs738409 polymorphism in patatin-like phospholipase 3 on the treatment efficacy of non-alcoholic fatty liver disease with type 2 diabetes mellitus.

scientific article

Inhibition of cholesterol crystallization under bilirubin deconjugation: partial characterization of mechanisms whereby infected bile accelerates pigment stone formation

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Inhibition of hepatocellular carcinoma by PegIFNα-2a in patients with chronic hepatitis C: a nationwide multicenter cooperative study

scientific article published on 9 August 2012

Initial experience with catheter probe US when using a multibending endoscope

scientific article published in June 2004

Integrated Resistance Analysis of CERTAIN-1 and CERTAIN-2 Studies in Hepatitis C Virus-Infected Patients Receiving Glecaprevir and Pibrentasvir in Japan

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Integrated analysis of 8-week glecaprevir/pibrentasvir in Japanese and overseas patients without cirrhosis and with hepatitis C virus genotype 1 or 2 infection

scientific article published on 13 March 2019

Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers

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Integration of hepatitis B virus DNA and hepatocellular carcinoma

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Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus

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Interferon combination and interferon-free anti-viral therapy

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Interferon decreases hepatocellular carcinogenesis in patients with cirrhosis caused by the hepatitis B virus ⬇️

scientific article published on March 1, 1998

Interferon lambda 4 polymorphism affects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C.

scientific article published on 6 May 2014

Interferon stimulated genes and innate immune activation following infection with hepatitis B and C viruses

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Interferon-stimulated gene of 20 kDa protein (ISG20) degrades RNA of hepatitis B virus to impede the replication of HBV in vitro and in vivo

scientific article published on 08 September 2016

Interleukin 28B polymorphism predicts interferon plus ribavirin treatment outcome in patients with hepatitis C virus-related liver cirrhosis: A multicenter retrospective study in Japan

scientific article published on 9 January 2014

Interleukin-28B polymorphisms and hepatitis C virus clearance.

scientific article published on 29 January 2013

Interleukin-28B single nucleotide polymorphism of donors and recipients can predict viral response to pegylated interferon/ribavirin therapy in patients with recurrent hepatitis C after living donor liver transplantation

scientific article published on September 2012

Interleukin-34 as a fibroblast-derived marker of liver fibrosis in patients with non-alcoholic fatty liver disease

scientific article published on July 2016

Interobserver and intraobserver agreement for gastric mucosa atrophy

scientific article published on 4 August 2015

Interrelationships Among Flow-Mediated Vasodilation, Nitroglycerine-Induced Vasodilation, Baseline Brachial Artery Diameter, Hyperemic Shear Stress, and Cardiovascular Risk Factors.

scientific article published on 29 December 2017

Intestinal Tuberculosis with Hoarseness as a Chief Complaint due to Mediastinal Lymphadenitis

scientific article published on 10 September 2011

Intima-media thickness of brachial artery, vascular function, and cardiovascular risk factors

scientific article published on 12 July 2012

Intra-arterial 5-fluorouracil/interferon combination therapy for advanced hepatocellular carcinoma with or without three-dimensional conformal radiotherapy for portal vein tumor thrombosis

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Intra-arterial 5-fluorouracil/interferon combination therapy for hepatocellular carcinoma with portal vein tumor thrombosis and extrahepatic metastases

scientific article published on 14 January 2010

Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.

scientific article published in September 2011

Investigation of Fluorodeoxyglucose Positron Emission Tomography for the Diagnosis of Solid Pseudopapillary Neoplasm of the Pancreas: A Study Associated With a National Survey of Solid Pseudopapillary Neoplasms

scientific article published on 01 November 2019

Investigation of each histological type in undifferentiated early gastric cancer and validity of diagnosis of the disease range

scientific article published on 19 November 2015

Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma

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Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease.

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Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression.

scientific article published on January 2009

Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma

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Involvement of proinflammatory cytokines IL-1beta and IL-6 in progression of human gastric carcinoma

scientific article published on 01 March 2005

Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway

scientific article published on November 2002

Is Occult Obscure Gastrointestinal Bleeding a Definite Indication for Capsule Endoscopy? A Retrospective Analysis of Diagnostic Yield in Patients with Occult versus Overt Bleeding.

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Is it possible to discriminate between neoplastic and nonneoplastic lesions in ulcerative colitis by magnifying colonoscopy?

scientific article published in March 2014

Is small-bowel capsule endoscopy effective for diagnosis of esophagogastric lesions related to portal hypertension?

scientific article published in March 2014

Is structural remodeling of fibrillated atria the consequence of tissue hypoxia?

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Isolated cardiac metastases of hepatocellular carcinoma after resection: a case report

scientific article published on 28 November 2019

Isolated granulomatous gastritis successfully treated by Helicobacter pylori eradication: a possible association between granulomatous gastritis and Helicobacter pylori

scientific article published in January 2003

JNJ-4178 (adafosbuvir, odalasvir, and simeprevir) in Japanese patients with chronic hepatitis C virus genotype 1 or 2 infection with or without compensated cirrhosis: the Phase IIa OMEGA-3 study

scientific article published on 17 February 2020

JSH Consensus Kobe 2009: Diagnosis and Treatment of Hepatitis B

JSH Guidelines for the Management of Hepatitis C Virus Infection: 2019 Update Protective effect of antiviral therapy against hepatocarcinogenesis

scientific article published on 16 April 2020

K-ras mutation in helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer

scientific article published in February 2002

Knack and practical technique of colonoscopic treatment focused on endoscopic mucosal resection using snare

scientific article published in July 2009

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

scientific article published on 08 June 2020

Late-onset ornithine transcarbamylase deficiency associated with hyperammonemia

scientific article published on 09 June 2017

Left atrial thickness under the catheter ablation lines in patients with paroxysmal atrial fibrillation: insights from 64-slice multidetector computed tomography

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Leptin causes nitric-oxide independent coronary artery vasodilation in humans

scientific article published on 01 February 2003

Leptin causes vasodilation in humans

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Less hydrophobic phosphatidylcholine species simplify biliary vesicle morphology, but induce bile metastability with a broad spectrum of crystal forms

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Letter of response to the editor

scientific article published on 14 October 2020

Levocarnitine Use Is Associated With Improvement in Sarcopenia in Patients With Liver Cirrhosis

Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure

scientific article published on 19 June 2018

Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus

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Little necessity of acid inhibition against proton pump inhibitor rebound effects and prior helicobacter pylori eradication therapy in gastric ulcer patients: a randomized prospective study.

scientific article published in May 2009

Liver fibrosis assessment by FibroScan compared with pathological findings of liver resection specimen in hepatitis C infection

scientific article published on 3 September 2016

Liver fibrosis assessments using FibroScan, virtual-touch tissue quantification, the FIB-4 index, and mac-2 binding protein glycosylation isomer levels compared with pathological findings of liver resection specimens in patients with hepatitis C inf

scientific article published on 25 September 2020

Long term persistence of NS5A inhibitor-resistant hepatitis C virus in patients who failed daclatasvir and asunaprevir therapy

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Long-Term Outcomes after Endoscopic Submucosal Dissection for Ulcerative Colitis-Associated Dysplasia

scientific article published on 10 October 2019

Long-term Ultrasonographic Follow-up Study of Gastric Motility in Patients with Functional Dyspepsia

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Long-term elimination of hepatitis C virus from human hepatocyte chimeric mice after interferon-γ gene transfer.

scientific article published on 28 December 2013

Long-term follow-up of clinical trial patients treated for chronic HCV infection with daclatasvir-based regimens

scientific article published on 21 September 2017

Long-term outcome of patients with gastric varices treated by balloon-occluded retrograde transvenous obliteration

scientific article published on 01 May 2014

Long-term outcome of stereotactic body radiotherapy for patients with small hepatocellular carcinoma

scientific article published on 14 January 2018

Long-term outcomes after endoscopic submucosal dissection for superficial colorectal tumors

scientific article published on 27 July 2016

Long-term outcomes after treatment for T1 colorectal carcinoma

scientific article published on 22 December 2015

Long-term outcomes after treatment for T1 colorectal carcinoma: a multicenter retrospective cohort study of Hiroshima GI Endoscopy Research Group

scientific article published on 13 February 2017

Long-term outcomes after treatment for pedunculated-type T1 colorectal carcinoma: a multicenter retrospective cohort study

scientific article published on 16 November 2015

Long-term outcomes of hepatic arterial port implantation using a coaxial microcatheter system in 176 patients with hepatocellular carcinoma

scientific article published on 01 March 2012

Long-term prognosis after endoscopic submucosal dissection for early gastric cancer in super-elderly patients

scientific article published on 5 February 2016

Long-term prognosis after treatment for T1 carcinoma of laterally spreading tumors: a multicenter retrospective study

scientific article published on 03 January 2019

Long-term use of entecavir in nucleoside-naïve Japanese patients with chronic hepatitis B infection

scientific article published on 24 March 2010

Low Levels of Low-Density Lipoprotein Cholesterol and Endothelial Function in Subjects without Lipid-Lowering Therapy

scientific article published on 24 November 2020

Low body mass index is a risk factor for impaired endothelium-dependent vasodilation in humans: role of nitric oxide and oxidative stress

scientific article published in July 2003

Low prevalence of Helicobacter pylori-negative gastric cancer among Japanese

scientific article published on 01 December 2011

Low serum level of hepatitis B core-related antigen indicates unlikely reactivation of hepatitis after cessation of lamivudine therapy

scientific article published on 01 August 2007

Low-dose intermittent interferon-alpha therapy for HCV-related liver cirrhosis after curative treatment of hepatocellular carcinoma

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Lymphatic vessel density at the site of deepest penetration as a predictor of lymph node metastasis in submucosal colorectal cancer

scientific article published on 01 January 2007

Lymphocyte subset characterization associated with persistent hepatitis C virus infection and subsequent progression of liver fibrosis

scientific article published on 15 June 2011

ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo.

scientific article published on 29 November 2010

Magnifying Endoscopy with Narrow Band Imaging in Estimating the Invasion Depth of Superficial Esophageal Squamous Cell Carcinomas

scientific article published on 25 July 2018

Magnifying colonoscopic features of ulcerative colitis reflect histologic inflammation

scientific article published on 01 November 2004

Magnifying endoscopy with narrow band imaging for diagnosis of colorectal tumors

scientific article published on 26 February 2007

Maintenance of low inflammation level by the ZFHX3 SNP rs2106261 minor allele contributes to reduced atrial fibrillation recurrence after pulmonary vein isolation

scientific article published in PLoS ONE

Major predictors and management of small-bowel angioectasia

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Major predictors of portal hypertensive enteropathy in patients with liver cirrhosis

scientific article published on 01 January 2015

Management of HCV patients in cases of direct-acting antiviral failure

scientific article published on 08 August 2019

Management of T1 colorectal carcinoma with special reference to criteria for curative endoscopic resection

scientific article published on 01 June 2012

Management of chronic hepatitis C and prevention of hepatocellular carcinoma

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Management of hepatitis B: Consensus of the Japan Society of Hepatology 2009.

scientific article published on 11 November 2010

Management of intraductal papillary-mucinous neoplasm of the pancreas: treatment strategy based on morphologic classification

scientific article published on 01 October 2006

Management of occult obscure gastrointestinal bleeding patients based on long-term outcomes.

scientific article published on 16 July 2018

Management of refractory ascites attenuates muscle mass reduction and improves survival in patients with decompensated cirrhosis

scientific article published on 04 September 2019

Matrix metalloproteinase-9 contributes to human atrial remodeling during atrial fibrillation

scientific article published in March 2004

Measurement of Rho-associated kinase (ROCK) activity in humans: validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil

scientific article published on 12 October 2010

Measurement of flow-mediated vasodilation of the brachial artery: a comparison of measurements in the seated and supine positions

scientific article published in May 2007

Measurement of hepatitis B virus core-related antigen is valuable for identifying patients who are at low risk of lamivudine resistance

scientific article published in February 2006

Mechanisms responsible for vasodilation upon magnesium infusion in vivo: clinical evidence.

scientific article

Medical malpractice litigation in gastroenterological practice in Japan: a 22-yr review of civil court cases

scientific article published on September 2006

Medical malpractice litigation related to gastrointestinal endoscopy in Japan: a two-decade review of civil court cases

scientific article published on November 2006

Mesenchymal Stem Cells Induce Epithelial to Mesenchymal Transition in Colon Cancer Cells through Direct Cell-to-Cell Contact

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Mesenchymal stem cells enhance growth and metastasis of colon cancer

scientific article published on 01 November 2010

Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia

scientific article published in March 2007

Meta-analysis used to identify factors associated with the effectiveness of proton pump inhibitors against non-erosive reflux disease

scientific article published on August 2009

Metabolomic-/Lipidomic-based Analysis of Plasma to Diagnose Hepatocellular Ballooning in Patients with Nonalcoholic Fatty Liver Disease: A Multicenter Study

scientific article published on 26 May 2020

MicroRNAs as Biomarkers for Liver Disease and Hepatocellular Carcinoma

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Microsatellite instability is a genetic marker for the development of multiple gastric cancers ⬇️

scientific article published on November 20, 2001

Microvascular structure and perfusion imaging of colon cancer by means of contrast-enhanced ultrasonography

scientific article published on 01 April 2012

Migration to the pulmonary artery of nine metallic coils placed in the internal iliac vein for treatment of giant rectal varices

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Mineralocorticoid Receptor Blocker Eplerenone Improves Endothelial Function and Inhibits Rho-Associated Kinase Activity in Patients With Hypertension ⬇️

scientific article published on December 28, 2011

Minute depressed colon cancer with submucosal invasion

scientific article published on 01 April 2003

Mnk1 is required for angiotensin II-induced protein synthesis in vascular smooth muscle cells

scientific article published on 6 November 2003

Modeling suggests that virion production cycles within individual cells is key to understanding acute hepatitis B virus infection kinetics

scientific article published in 2023

Modeling-based response-guided therapy for chronic hepatitis C under glecaprevir/pibrentasvir may identify patients for ultra-short treatment duration

scientific article published on 04 May 2020

Modifying Effect of Chronic Atrophic Gastritis on Radiation Risk for Noncardia Gastric Cancer According to Histological Type

scientific article published on 01 August 2020

Molecular Mechanisms of Hepatocarcinogenesis Following Sustained Virological Response in Patients with Chronic Hepatitis C Virus Infection

scientific article published in 2018

Molecular analysis of intraspousal transmission of hepatitis C virus ⬇️

scientific article published on April 1, 1995

Molecular evolutionary analyses implicate injection treatment for schistosomiasis in the initial hepatitis C epidemics in Japan

scientific article published on January 2005

Molecular mechanism of infectious HCV particle production

scientific article published on December 2015

Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human esophageal squamous cell carcinomas

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Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human gastric carcinomas.

scientific article published on April 2003

Monocyte chemoattractant protein-1 transfection induces angiogenesis and tumorigenesis of gastric carcinoma in nude mice via macrophage recruitment

scientific article published on November 2005

Morbidly obese patient with non-alcoholic steatohepatitis-related cirrhosis who died from sepsis caused by dental infection of Porphyromonas gingivalis: A case report

scientific article published on 5 May 2015

Mouse model of proximal colon-specific tumorigenesis driven by microsatellite instability-induced Cre-mediated inactivation of Apc and activation of Kras.

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Mucin phenotype and background mucosa of intramucosal differentiated-type adenocarcinoma of the stomach

scientific article published on 01 January 2004

Multicentric hepatocarcinogenesis at 6 and 13 years after sustained viral response to hepatitis C virus

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Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma

scientific article published on 10 February 2016

Multiple carcinoid tumors of the ileum preoperatively diagnosed by enteroscopy with the double-balloon technique

scientific article published on 01 August 2005

Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system

scientific article published on 23 June 2014

Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1alpha

scientific article published in February 2004

Myocardial bridging increases the risk of coronary spasm

scientific article published in August 2003

NUDT3 rs206936 is associated with body mass index in obese Japanese women

scientific article published on 25 May 2013

Narrow-band imaging magnification predicts the histology and invasion depth of colorectal tumors

scientific article published in March 2009

Natural course of lugol-voiding lesions in patients with superficial esophageal squamous cell carcinoma

scientific article published on 5 March 2010

Natural histories of hepatitis C virus infection in men and women simulated by the Markov model

scientific article published in July 2003

Necessity of Multiple Gastric Biopsies from Different Sites for Detection of Clarithromycin-Resistant Helicobacter pylori Strains ⬇️

scientific article published on September 1, 2003

Neuropilin-1 is involved in regulation of apoptosis and migration of human colon cancer

scientific article published on July 2006

New assessment of endothelial function measured by short time flow-mediated vasodilation: Comparison with conventional flow-mediated vasodilation measurement

scientific article published on 04 May 2018

New insight into the enhanced effect of pegylated interferon-α.

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New method of evaluating gastric mucosal blood flow by ultrasound

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Nicorandil enhances myocardial tolerance to ischemia without progressive collateral recruitment during coronary angioplasty

scientific article published in April 2002

Nicorandil-induced preconditioning as evidenced by troponin T measurements after coronary angioplasty in patients with stable angina pectoris

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Nifedipine interferes with migration of vascular smooth muscle cells via inhibition of Pyk2-Src axis.

scientific article published on 25 June 2009

Nitroglycerine-induced vasodilation for assessment of vascular function: a comparison with flow-mediated vasodilation.

scientific article published on 21 March 2013

Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease

scientific article published on 15 June 2016

Nodular gastritis in adults is caused by Helicobacter pylori infection

scientific article published in May 2003

Non-SCN5A related Brugada syndromes: verification of normal splicing and trafficking of SCN5A without exonic mutations

scientific article published on 01 January 2007

Non-invasive assessment of liver steatosis in non-alcoholic fatty liver disease

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Non-invasive liver fibrosis score calculated by combination of virtual touch tissue quantification and serum liver functional tests in chronic hepatitis C patients

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Non-polypoid colorectal neoplasms in ulcerative colitis

scientific article published on July 2010

Non-ulcer dyspepsia and H. pylori

scientific article published in February 2002

Nonalcoholic fatty liver disease and cardiovascular disease

scientific article published on 01 January 2014

Noninvasive scoring systems in patients with nonalcoholic fatty liver disease with normal alanine aminotransferase levels.

scientific article published on 27 November 2012

Nonpolypoid (flat and depressed) colorectal neoplasms

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Novel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection

scientific article published on 23 October 2015

Novel robust in vitro hepatitis B virus infection model using fresh human hepatocytes isolated from humanized mice

scientific article published on 17 March 2015

Occupational Radiation Exposure during Endoscopic Retrograde Cholangiopancreatography and Usefulness of Radiation Protective Curtains

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On-treatment low serum HBV RNA level predicts initial virological response in chronic hepatitis B patients receiving nucleoside analogue therapy.

scientific article published on 16 April 2014

Optical biopsy of GI lesions by reflectance-type laser-scanning confocal microscopy

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Optical biopsy of early gastroesophageal cancer by catheter-based reflectance-type laser-scanning confocal microscopy

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Optimal Target Level of Low-density Lipoprotein Cholesterol for Vascular Function in Statin Naïve Individuals.

scientific article published on 21 August 2017

Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection

scientific article published on 14 September 2014

Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease.

scientific article published on 5 April 2009

Outcome of endoscopic submucosal dissection for colorectal tumors accompanied by fibrosis

scientific article published on 14 July 2010

Outcome of endoscopic submucosal dissection for gastric neoplasm in relationship to endoscopic classification of submucosal fibrosis

scientific article published on 7 October 2012

Outcome of patients who have undergone total enteroscopy for obscure gastrointestinal bleeding

scientific article published on February 2012

Oxidative stress, endothelial function and angiogenesis induced by cell therapy and gene therapy

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PD1 gene polymorphism is associated with a poor prognosis in hepatocellular carcinoma following liver resection, cohort study

scientific article published on 29 June 2020

PDE5 inhibitor sildenafil citrate augments endothelium-dependent vasodilation in smokers

scientific article published on 14 April 2003

PNPLA3 and HLA-DQB1 polymorphisms are associated with hepatocellular carcinoma after hepatitis C virus eradication

scientific article published on 15 October 2020

Pan-genotypic cell culture system for propagation of hepatitis C virus clinical isolates

scientific article published on 2 August 2016

Partial characterization of cytoprotective mechanisms of lecithin against bile salt-induced bile duct damage

scientific article published in October 2004

Pathogenetic role of the tyrosine-phosphorylated CagA EPIYA sequence of Helicobacter pylori in histological gastritis in Japanese patients

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Pathogenic Significance and Organic Virus Levels in Patients Infected with TT Virus ⬇️

scientific article published on January 1, 2001

Patients with early recurrence of hepatocellular carcinoma have poor prognosis

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Pedunculated-type T1 colorectal carcinoma with lung carcinoma metastasis at the deepest invasive portion

scientific article published on 3 June 2016

Percutaneous radiofrequency ablation as first-line treatment for small hepatocellular carcinoma: results and prognostic factors on long-term follow up.

scientific article published on 14 January 2010

Percutaneous transvenous embolization for portosystemic shunts associated with encephalopathy: Long-term outcomes in 14 patients

scientific article published on 11 July 2013

Percutaneous transvenous shunt occlusion for portosystemic encephalopathy due to lenvatinib administration to a patient with hepatocellular carcinoma and portosystemic shunt

scientific article published on 31 January 2019

Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients

scientific article published on 26 November 2007

Persistent Loss of Hepatitis B Virus Markers in Serum without Cellular Immunity by Combination of Peginterferon and Entecavir Therapy in Humanized Mice

scientific article published on 10 July 2017

Pilot study of stereotactic body radiation therapy combined with transcatheter arterial chemoembolization for small hepatocellular carcinoma

article by Yohji Honda et al published 1 January 2014 in Hepato-Gastroenterology

Pilot study of systemic combination therapy with S-1, an oral fluoropyrimidine, and cisplatin for hepatocellular carcinoma with extrahepatic metastases.

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Pilot study of tenofovir disoproxil fumarate and pegylated interferon-alpha 2a add-on therapy in Japanese patients with chronic hepatitis B

scientific article published on 14 July 2020

Pioglitazone improves endothelium-dependent vasodilation in hypertensive patients with impaired glucose tolerance in part through a decrease in oxidative stress

scientific article published on 4 January 2010

Platelet count for predicting fibrosis in nonalcoholic fatty liver disease

scientific article published on 13 July 2011

Plaunotol induces a comparative increase of acidic mucin fraction in gastric juice

scientific article published on 01 March 2011

Polidocanol injection therapy for small-bowel hemangioma by using double-balloon endoscopy

scientific article published on 22 February 2016

Polysaccharides derived from Ganoderma lucidum fungus mycelia ameliorate indomethacin-induced small intestinal injury via induction of GM-CSF from macrophages

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Poor oral health, that is, decreased frequency of tooth brushing, is associated with endothelial dysfunction

scientific article published on 05 February 2014

Population Pharmacokinetics of Glecaprevir/Pibrentasvir in HCV-infected Japanese Subjects in Phase 3 CERTAIN-1 and CERTAIN-2 Trials

scientific article published on 12 September 2019

Portal-systemic shunt between the inferior mesenteric vein and inferior vena cava in a patient with hepatic encephalopathy: successful occlusion by balloon-occluded retrograde transvenous obliteration

scientific article published on 01 March 2011

Possibility of adoptive immunotherapy with peripheral blood-derived CD3⁻CD56+ and CD3+CD56+ cells for inducing antihepatocellular carcinoma and antihepatitis C virus activity.

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Postprandial insulin secretion pattern is associated with histological severity in non-alcoholic fatty liver disease patients without prior known diabetes mellitus

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Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection

Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells

scientific article published on April 2003

Potential of Helicobacter pylori-uninfected signet ring cell carcinoma to invade the submucosal layer

scientific article published on 30 May 2019

Potential role for vascular endothelial growth factor-D as an autocrine factor for human gastric carcinoma cells

scientific article published on 6 July 2010

Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor

scientific article published on 17 February 2010

Pre-impaired fasting glucose state is a risk factor for endothelial dysfunction: Flow-mediated Dilation Japan (FMD-J) study

scientific article published on 01 October 2020

Preceding endoscopic submucosal dissection for T1 colorectal carcinoma does not affect the prognosis of patients who underwent additional surgery: a large multicenter propensity score-matched analysis

scientific article published on 18 May 2019

Preclinical Pharmacological Development of Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection.

scientific article published on 24 January 2018

Preconditioning effect during coronary angioplasty in patients with stable angina pectoris.

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Predicting atrial fibrillation using a combination of genetic risk score and clinical risk factors

scientific article published on 11 January 2020

Predicting the absence of lymph node metastasis of submucosal invasive gastric cancer: expansion of the criteria for curative endoscopic resection

scientific article published on 20 July 2010

Predicting the clinical response to cytapheresis in steroid-refractory or -dependent ulcerative colitis using contrast-enhanced ultrasonography

scientific article published in January 2009

Predicting the need for surgery in Crohn's disease with contrast harmonic ultrasound

scientific article published in May 2007

Predicting the response to 48-week combination therapy with peginterferon alpha-2b plus ribavirin from the estimated HCV RNA load index after negative serum change in genotype 1b hepatitis C patients

scientific article published on 25 February 2009

Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.

scientific article published in June 2011

Predictive Factors of Portal Hypertensive Enteropathy Exacerbation in Patients with Liver Cirrhosis: A Capsule Endoscopy Study

scientific article published on 19 April 2018

Predictive value of the IFNL4 polymorphism on outcome of telaprevir, peginterferon, and ribavirin therapy for older patients with genotype 1b chronic hepatitis C.

scientific article published on 21 December 2013

Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.

scientific article published on 19 September 2010

Predictive values of amino acid sequences of the core and NS5A regions in antiviral therapy for hepatitis C: a Japanese multi-center study

scientific article published on 11 June 2009

Predictors and long-term prognostic implications of angiographic slow/no-flow during percutaneous coronary intervention for acute myocardial infarction

scientific article published on 15 May 2008

Predictors of incomplete resection and perforation associated with endoscopic submucosal dissection for colorectal tumors.

scientific article published on 7 November 2013

Preoperative Biliary Drainage in Cases of Borderline Resectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgery

scientific article published on 6 January 2016

Preoperative Fluorine 18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography for Prediction of Microvascular Invasion in Small Hepatocellular Carcinoma

scientific article published on 10 March 2016

Preoperative PET-CT is useful for predicting recurrent extrahepatic metastasis of hepatocellular carcinoma after resection

scientific article published on 11 January 2020

Presence of poorly differentiated component correlated with submucosal invasion in the early diffuse-type gastric cancer.

scientific article published in November 2008

Pretreatment predictor of response, time to progression, and survival to intraarterial 5-fluorouracil/interferon combination therapy in patients with advanced hepatocellular carcinoma.

scientific article

Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2009 to 2010 in Japan: a multicenter large retrospective study

scientific article published on 11 February 2012

Prevalence and impact of musculoskeletal pain in Japanese gastrointestinal endoscopists: a controlled study

scientific article

Prevalence of Helicobacter pylori resistance to clarithromycin and metronidazole determined by 23S ribosomal RNA and rdxA gene analyses in Hiroshima, Japan

scientific article published in October 2003

Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice

scientific article published on 2 April 2018

Prevention of hepatitis B virus reactivation in immunosuppressive therapy or chemotherapy

scientific article published on June 2011

Prevention of recurrence of hepatocellular carcinoma with anti-viral therapy for hepatitis C virus

scientific article published on December 2015

Prognostic value of p53 and Ki-67 expression in resected or biopsy specimens of bile duct carcinoma

scientific article published on 01 September 2003

Programs for continuing medical education: a session; 2. Current therapy for chronic hepatitis C

scientific article published in March 2014

Prolongation of interferon therapy for recurrent hepatitis C after living donor liver transplantation: analysis of predictive factors of sustained virological response, including amino acid sequence of the core and NS5A regions of hepatitis C virus

scientific article published on 22 July 2010

Prolonged negative HCV-RNA status led to a good outcome in chronic hepatitis C patients with genotype 1b and super-high viral load

scientific article published on 21 August 2006

Promoter methylation of cyclin D2 gene in gastric carcinoma

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Prophylaxis against recurrence of HBV hepatitis after living-donor liver transplantation.

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Prospective study of short-term peginterferon-alpha-2a monotherapy in patients who had a virological response at 2 weeks after initiation of interferon therapy

scientific article published on 01 April 2008

Protease Inhibitor Resistance Remains Even After Mutant Strains Become Undetectable by Deep Sequencing

scientific article published on 20 September 2016

Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis

scientific article published on 24 October 2019

Publisher Correction: Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP

scientific article published on 05 February 2020

Pulverized konjac glucomannan ameliorates oxazolone-induced colitis in mice.

scientific article

Pycnogenol, French maritime pine bark extract, augments endothelium-dependent vasodilation in humans

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Quantitative analysis and development of a computer-aided system for identification of regular pit patterns of colorectal lesions

scientific article published in November 2010

Quantitative analysis of colorectal lesions observed on magnified endoscopy images

scientific article published on 16 September 2011

Quantitative analysis of lymphangiogenic markers for predicting metastasis of human gastric carcinoma to lymph nodes.

scientific article published in June 2005

Quantitative effect of natural killer-cell licensing on hepatocellular carcinoma recurrence after curative hepatectomy

scientific article published on 18 August 2014

Quantitative identification of mucosal gastric cancer under magnifying endoscopy with flexible spectral imaging color enhancement.

scientific article published in May 2013

Quasispecies of Hepatitis C Virus Participate in Cell-Specific Infectivity

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RNA Exosome Complex Regulates Stability of the Hepatitis B Virus X-mRNA Transcript in a Non-stop-mediated (NSD) RNA Quality Control Mechanism

scientific article published on 8 June 2016

Randomized Phase 3 Trial of Ombitasvir/Paritaprevir/Ritonavir and Ribavirin for Hepatitis C Virus Genotype 2-Infected Japanese Patients

scientific article published on 23 May 2017

Randomized comparison of daclatasvir + asunaprevir versus telaprevir + peginterferon/ribavirin in Japanese hepatitis C virus patients

scientific article

Randomized phase 3 trial of ombitasvir/paritaprevir/ritonavir for hepatitis C virus genotype 1b-infected Japanese patients with or without cirrhosis

scientific article published on 03 July 2015

Randomized trial of high-dose interferon-alpha-2b combined with ribavirin in patients with chronic hepatitis C: Correlation between amino acid substitutions in the core/NS5A region and virological response to interferon therapy

scientific article published on April 2009

Randomized trial of interferon- and ribavirin-free ombitasvir/paritaprevir/ritonavir in treatment-experienced hepatitis C virus-infected patients

scientific article published on 23 March 2015

Range of Normal Liver Stiffness and Factors Associated With Increased Stiffness Measurements in Apparently Healthy Individuals

scientific article published on 07 September 2018

Rapid and persistent decline in soluble CD163 with successful direct-acting antiviral therapy and associations with chronic hepatitis C histology

scientific article published on 10 July 2018

Rapid emergence of telaprevir resistant hepatitis C virus strain from wildtype clone in vivo

scientific article published on 2 August 2011

Rapid progression of Epstein-Barr-virus-positive gastric diffuse large B-cell lymphoma during chemoradiotherapy: a case report

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Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay

scientific article

Rare quasispecies in the YMDD motif of hepatitis B virus detected by polymerase chain reaction with peptide nucleic acid clamping

scientific article published in January 2003

Rate of unintended Helicobacter pylori eradication in the Vietnamese

scientific article

Ratio of serum levels of AGEs to soluble form of RAGE is a predictor of endothelial function

scientific article published on 21 October 2014

Reactive hyperemia-peripheral arterial tonometry is useful for assessment of not only endothelial function but also stenosis of the digital artery.

scientific article published in June 2018

Real-time visualization and quantitation of canine gastric mucosal blood flow by contrast-enhanced ultrasonography

scientific article published in July 2006

Real-word efficacy of sofosbuvir, velpatasvir plus ribavirin therapy for chronic hepatitis patients who failed to prior DAA therapy with NS5A-P32 deletion mutated HCV infection

scientific article published on 12 July 2020

Real-world efficacy and safety of daclatasvir and asunaprevir therapy for hepatitis C virus-infected cirrhosis patients

scientific article published on 11 August 2016

Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures

scientific article published on 17 October 2018

Real-world efficacy of sofosbuvir plus velpatasvir therapy for patients with hepatitis C virus-related decompensated cirrhosis

scientific article published on 11 September 2020

Real-world learning curve analysis of colorectal endoscopic submucosal dissection: a large multicenter study

scientific article published on 03 September 2019

Real-world virological efficacy and safety of daclatasvir/asunaprevir/beclabuvir in patients with chronic hepatitis C virus genotype 1 infection in Japan

scientific article published on 08 March 2019

Recent trend of clinical features in patients with hepatocellular carcinoma

scientific article published on 13 December 2011

Rectal Lymphoid Follicle Aphthous Lesions Frequently Progress to Ulcerative Colitis with Proximal Extension

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Reduced Human α-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease

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Reduced expression of heme oxygenase-1 in patients with coronary atherosclerosis

scientific article published on 01 April 2007

Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study

scientific article published on 01 January 2018

Regression of Cecal MALT Lymphoma after Antibiotic Treatment in a Patient with Helicobacter pylori Infection

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Regression of Idiopathic Thrombocytopenic Purpura in a Patient With Eradication of Hepatitis C Virus by Direct-Acting Antivirals

scientific article published on 11 October 2019

Regular surveillance by imaging for early detection and better prognosis of hepatocellular carcinoma in patients infected with hepatitis C virus

scientific article published on 29 October 2009

Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP

scientific article published on 11 June 2019

Regulation of vascular endothelial growth factor (VEGF)-C and VEGF-D expression by the organ microenvironment in human colon carcinoma.

scientific article published on July 2004

Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia: evaluation by transabdominal ultrasonography

scientific article published on 01 July 2008

Relation of the Bilateral Earlobe Crease to Endothelial Dysfunction.

scientific article published on 29 March 2017

Relationship between Helicobacter pylori tyrosine-phosphorylated CagA-related markers and the development of diffuse-type gastric cancers: a case-control study

scientific article published on 9 February 2010

Relationship between augmentation index and flow-mediated vasodilation in the brachial artery

scientific article published in July 2008

Relationship between endothelial function in the coronary and brachial arteries.

scientific article published in October 2005

Relationship between flow-mediated vasodilation and cardiovascular risk factors in a large community-based study.

scientific article published on 23 October 2013

Relationship between high-density lipoprotein cholesterol levels and endothelial function in women: a cross-sectional study

scientific article published on 07 July 2020

Relationship between home blood pressure and vascular function in patients receiving antihypertensive drug treatment

scientific article published on 07 March 2019

Relationship between narrow-band imaging magnifying observation and pit pattern diagnosis in colorectal tumors

scientific article published on 21 January 2013

Relationship between nitroglycerine-induced vasodilation and clinical severity of peripheral artery disease

scientific article published on 26 April 2014

Relationship between serum triglyceride levels and endothelial function in a large community-based study.

scientific article published in April 2016

Relationships Between Calcium Channel Blockers and Vascular Function Tests

scientific article published on 01 June 2019

Reliable and cost-effective screening of inherited heterozygosity by Zn2+-cyclen polyacrylamide gel electrophoresis

scientific article published in November 2005

Removal of a sewing needle penetrating the wall of the third portion of the duodenum by double-balloon endoscopy

scientific article published on 28 December 2011

Renal endothelial dysfunction and hypertension

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Renal metastasis from primary hepatocellular carcinoma: a case report

scientific article published on 25 March 2020

Repetition of ischemic preconditioning augments endothelium-dependent vasodilation in humans: role of endothelium-derived nitric oxide and endothelial progenitor cells

scientific article published on 19 April 2007

Replication study of 15 recently published Loci for body fat distribution in the Japanese population.

scientific article published on 7 December 2012

Reply: Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity -matched analysis in a single institution

scientific article published on 22 February 2019

Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection.

scientific article

Resistance Characterization of Hepatitis C Virus Genotype 2 from Japanese Patients Treated with Ombitasvir and Paritaprevir/Ritonavir.

scientific article

Response

scientific article published on 01 June 2013

Response

scientific article published on 01 November 2016

Response of the left anterior descending coronary artery to acetylcholine in patients with chest pain and angiographically normal coronary arteries

scientific article published in December 2003

Response to "treatment guidelines for HCV genotype 1: mono for low, triple for high, and dual for 'middle'?"

scientific article published on 13 February 2013

Retrograde venography during balloon-occluded retrograde transvenous obliteration of gastric varices

scientific article published on 13 January 2017

Retrospective Identification of Herpes Simplex 2 Virus-Associated Acute Liver Failure in an Immunocompetent Patient Detected Using Whole Transcriptome Shotgun Sequencing.

scientific article published on 26 December 2017

Rho-associated kinase activity is a predictor of cardiovascular outcomes.

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Rho-associated kinase activity is an independent predictor of cardiovascular events in acute coronary syndrome.

scientific article published on 17 August 2015

Rho-associated kinase activity, endothelial function, and cardiovascular risk factors

scientific article published on 07 July 2011

Ribavirin induces hepatitis C virus genome mutations in chronic hepatitis patients who failed to respond to prior daclatasvir plus asunaprevir therapy

scientific article published on 16 October 2019

Risk analysis of submucosal invasive rectal carcinomas for lymph node metastasis to expand indication criteria for endoscopic resection

scientific article published on May 2013

Risk factors and management of positive horizontal margin in early gastric cancer resected by en bloc endoscopic submucosal dissection

scientific article published on 16 April 2014

Risk factors for bleeding after endoscopic submucosal dissection of gastric epithelial neoplasm

scientific article published on 10 May 2011

Risk factors for delayed bleeding after endoscopic submucosal dissection for colorectal neoplasms

scientific article published on 14 May 2014

Risk factors for esophageal stenosis after entire circumferential endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma

scientific article published on 24 December 2015

Risk factors for exacerbation of gastroesophageal varices and portosystemic encephalopathy during treatment with nucleos(t)ide analogs for hepatitis B virus-related cirrhosis

scientific article published on 8 November 2017

Risk factors for hepatocellular carcinoma in a Japanese population: a nested case-control study

scientific article published on April 2008

Risk factors for histological progression of non-alcoholic steatohepatitis analyzed from repeated biopsy cases

scientific article published on 02 January 2020

Risk factors for the exacerbation of esophageal varices or portosystemic encephalopathy after sustained virological response with IFN therapy for HCV-related compensated cirrhosis

scientific article published on 05 October 2012

Risk factors for vertical incomplete resection in endoscopic submucosal dissection as total excisional biopsy for submucosal invasive colorectal carcinoma

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Risk of bleeding after endoscopic submucosal dissection for colorectal tumors in patients with continued use of low-dose aspirin

scientific article published on 15 February 2015

Risk of lymph node metastasis in colorectal T1 (SM) carcinoma

scientific article published on 01 November 2016

Risk stratification of ventricular fibrillation in Brugada syndrome using noninvasive scoring methods

scientific article published on 13 July 2016

Role of 3-D conformal radiotherapy for major portal vein tumor thrombosis combined with hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma

scientific article published on 19 August 2014

Role of Helicobacter pylori infection and chronic inflammation in gastric cancer in the cardia

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Role of Natural Killer T Cells in the Mouse Colitis‐Associated Colon Cancer Model ⬇️

scientific article published on 01 January 2012

Role of the JNK pathway in thrombin-induced ICAM-1 expression in endothelial cells

scientific article published on 23 June 2005

Role of the angiotensin II type 2 receptor in arterial remodeling after wire injury in mice

scientific article published on 01 June 2008

Role of the gastrin-gastrin receptor system in the expansive growth of human gastric neoplasms

scientific article published on 10 December 2008

Roles of rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness

scientific article published on 26 January 2007

Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction

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Safety and efficacy of dual therapy with daclatasvir and asunaprevir for older patients with chronic hepatitis C.

scientific article published on 8 September 2016

Safety and feasibility of diet-treated donors with steatotic livers at the initial consultation for living-donor liver transplantation

scientific article published on 01 May 2012

Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease

scientific article published on 01 April 2007

Sarpogrelate hydrochloride, a selective 5-hydroxytryptamine(2A) antagonist, augments autologous bone marrow mononuclear cell implantation-induced improvement in endothelium-dependent vasodilation in patients with critical limb ischemia

scientific article published in January 2010

Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor

scientific article published on 19 February 2019

Screening of genes specifically activated in the pancreatic juice ductal cells from the patients with pancreatic ductal carcinoma

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Selective decrease in colonic CD56(+) T and CD161(+) T cells in the inflamed mucosa of patients with ulcerative colitis

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Ser96Ala genetic variant of the human histidine-rich calcium-binding protein is a genetic predictor of recurrence after catheter ablation in patients with paroxysmal atrial fibrillation

scientific article published on 06 March 2019

Serial amino acid sequence change in the hypervariable region of hepatitis C virus

scientific article published on 01 July 1994

Serial profiling of circulating tumor DNA for optimization of anti-VEGF chemotherapy in metastatic colorectal cancer patients

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Serial profiling of circulating tumor DNA identifies biomarkers for anti-VEGF chemotherapy in mCRC patients

scientific article published on 01 October 2017

Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model

scientific article published on 24 May 2006

Serological Evaluation of Gastric Cancer Risk Based on Pepsinogen and Helicobacter pylori Antibody: Relationship to Endoscopic Findings

scientific article published on 2 June 2017

Serological comparison of serum pepsinogen and anti-parietal cell antibody levels between Japanese and German patients

scientific article published on 01 February 2002

Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients.

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Serum HBV RNA is a predictor of early emergence of the YMDD mutant in patients treated with lamivudine

scientific article published in May 2007

Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy.

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Serum PAI‐1 is a novel predictor for response to pegylated interferon‐α‐2b plus ribavirin therapy in chronic hepatitis C virus infection ⬇️

scientific article published on September 14, 2011

Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease

scientific article published on 14 October 2016

Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission

scientific article published on 03 April 2020

Serum asymmetric dimethylarginine levels are independently associated with procollagen III N-terminal peptide in nonalcoholic fatty liver disease patients

scientific article published on 23 November 2012

Serum des-gamma-carboxyprothrombin concentration determined by the avidin-biotin complex method in small hepatocellular carcinomas ⬇️

scientific article published on December 1, 1994

Serum interleukin-6 associated with hepatocellular carcinoma risk: a nested case-control study.

scientific article published on 16 July 2013

Serum levels of pigment epithelium-derived factor (PEDF) are independently associated with procollagen III N-terminal peptide levels in patients with nonalcoholic fatty liver disease

scientific article published on 3 August 2012

Serum miR-379 expression is related to the development and progression of hypercholesterolemia in non-alcoholic fatty liver disease

scientific article published on 27 February 2020

Serum pepsinogen concentration as a marker of Helicobacter pyloriinfection and the histologic grade of gastritis; evaluation of gastric mucosa by serum pepsinogen levels

scientific article published on 01 January 2003

Serum pepsinogen levels in the Japanese population: prospective study of 9 years of follow-up

scientific article published on 01 September 2007

Serum screening for detection of high-risk group for early-stage diffuse type gastric cancer in Japanese

scientific article published in March 2012

Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse.

scientific article published on 10 July 2012

Severity of hypertension affects improved resistance artery endothelial function by angiotensin-converting enzyme inhibition

scientific article published in May 2002

Short-term outcomes of endoscopic submucosal dissection for superficial cecal tumors: a comparison between extension and nonextension into the appendiceal orifice.

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Should splenectomy be performed for hepatitis C patients undergoing living-donor liver transplantation?

scientific article published on 01 June 2007

Signal activation of hepatitis B virus-related hepatocarcinogenesis by upregulation of SUV39h1

scientific article published on 09 June 2020

Significance of an exaggerated meal-stimulated gastrin response in pathogenesis of Helicobacter pylori-negative duodenal ulcer

scientific article published in April 2003

Significance of non-alcoholic fatty liver disease in Crohn's disease: A retrospective cohort study

scientific article published on 13 October 2016

Significant correlation between spleen volume and thrombocytopenia in liver transplant patients: a concept for predicting persistent thrombocytopenia

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Significant regression of a cavernous hepatic hemangioma to a sclerosed hemangioma over 12 years: a case study

scientific article published in June 2011

Silencing of Discoidin Domain Receptor-1 (DDR1) Concurrently Inhibits Multiple Steps of Metastasis Cascade in Gastric Cancer.

scientific article published on 13 March 2018

Similar effects of recombinant interferon-alpha-2b and natural interferon-alpha when combined with intra-arterial 5-fluorouracil for the treatment of advanced hepatocellular carcinoma

scientific article published in November 2007

Simple scoring system for predicting cirrhosis in nonalcoholic fatty liver disease.

scientific article

Single administration of ecabet sodium diminishes the level of delta-13CO2 in urea breath test

scientific article published in January 2002

Single dose of OCH improves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of valpha14 natural killer T cells in mice

scientific article published on 01 January 2005

Single lymphocyte analysis with a microwell array chip

scientific article

Single nucleotide polymorphism in the hypoxia-inducible factor-1alpha gene in colorectal carcinoma.

scientific article published in November 2004

Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C.

scientific article

Sinusoidal obstruction syndrome post-treatment with trastuzumab emtansine (T-DM1) in advanced breast cancer

scientific article published on 24 October 2019

Skeletal Muscle Loss during Tyrosine Kinase Inhibitor Treatment for Advanced Hepatocellular Carcinoma Patients

scientific article published on 08 November 2019

Small bowel abnormalities in patients with compensated liver cirrhosis.

scientific article published on 18 December 2012

Small hepatocellular carcinoma: evaluation of portal blood flow with CT during arterial portography performed with balloon occlusion of the hepatic artery ⬇️

scientific article published on October 1, 1994

Small rectal carcinoid with lymph node metastasis diagnosed prior to treatment

scientific article published in February 2003

Smoking activates rho-kinase in smooth muscle cells of forearm vasculature in humans

scientific article published on 7 April 2003

Smoking cessation reverses DNA double-strand breaks in human mononuclear cells

scientific article

Smoking, endothelial function, and Rho-kinase in humans

scientific article

Sofosbuvir-velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 hepatitis C who failed direct-acting antivirals

scientific article published on 20 July 2018

Somatic mutation in mitochondrial DNA and nuclear microsatellite instability in gastric cancer.

scientific article published on November 2003

Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer.

scientific article

Somatic mutations of mitochondrial DNA in digestive tract cancers

scientific article published on 01 November 2005

Splenectomy in chronic hepatic disorders: portal vein thrombosis and improvement of liver function

scientific article published on 04 February 2011

Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells

scientific article published on 17 June 2011

Stepped assessment of gastric emptying of a solid meal using the (13)C-octanoic acid breath test

scientific article published on 01 June 2007

Stereotactic body radiation therapy combined with transcatheter arterial chemoembolization for small hepatocellular carcinoma

scientific article published in March 2013

Stereotactic body radiotherapy for patients with small hepatocellular carcinoma ineligible for resection or ablation therapies

scientific article published on 16 June 2014

Strategy for treatment of nonerosive reflux disease in Asia

scientific article published on May 2008

Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer

scientific article

Stromal reaction inhibitor and immune-checkpoint inhibitor combination therapy attenuates excluded-type colorectal cancer in a mouse model

scientific article published on 28 October 2020

Successful Use of Adalimumab for Treating Pyoderma Gangrenosum with Ulcerative Colitis under Corticosteroid-tapering Conditions

scientific article

Successful hepatitis B vaccination in liver transplant recipients with donor-specific hyporesponsiveness.

scientific article published on 17 March 2009

Successful retreatment with 12 weeks of glecaprevir and pibrentasvir for a genotype 2a HCV-infected hemodialysis patient who failed to respond to 8 weeks of prior glecaprevir and pibrentasvir therapy

scientific article published on 28 August 2019

Successful treatment of an entecavir-resistant hepatitis B virus variant

scientific article published in December 2007

Successful treatment of pulmonary metastases associated with advanced hepatocellular carcinoma by systemic 5-fluorouracil combined with interferon-alpha in a hemodialysis patient

scientific article published on 28 October 2008

Successive, rapid recurrences of in-stent restenoses in a woman with angina pectoris

scientific article published in November 2006

Suppression of STAT3 activity by Duplin, which is a negative regulator of the Wnt signal

scientific journal article

Suppression of interferon-related promoter activation by hepatitis C virus proteins expressed in cultured cells

scientific article published in September 2006

Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats

scientific article published in January 2005

Surface structure of antral gastric mucosa represents the status of histologic gastritis: fundamental evidence for the evaluation of antral gastritis by magnifying endoscopy

scientific article published on 01 May 2006

Surgical treatment for portosystemic encephalopathy in patients with liver cirrhosis: Occlusion of portosystemic shunt in combination with splenectomy

scientific article published on 26 June 2012

Susceptibility of chimeric mice with livers repopulated by serially subcultured human hepatocytes to hepatitis B virus

scientific article published in February 2008

Sustained virological response to antiviral therapy improves survival rate in patients with recurrent hepatitis C virus infection after liver transplantation

scientific article published on 5 November 2014

Synchronous and Subsequent Lesions of Serrated Adenomas and Tubular Adenomas of the Colorectum ⬇️

scientific article published on November 29, 2010

Systemic gemcitabine combined with intra-arterial low-dose cisplatin and 5-fluorouracil for advanced hepatocellular carcinoma: seven cases

scientific article

TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis

scientific article published on 4 May 2016

Taking Warfarin with Heparin Replacement and Direct Oral Anticoagulant Is a Risk Factor for Bleeding after Endoscopic Submucosal Dissection for Early Gastric Cancer

scientific article published on 8 February 2018

Target of Triglycerides as Residual Risk for Cardiovascular Events in Patients With Coronary Artery Disease　- Post Hoc Analysis of the FMD-J Study A

scientific article published on 26 March 2019

Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease

scientific article published on 13 March 2014

Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma

scientific article published on 26 March 2020

Telaprevir is effective given every 12 h at 750 mg with pegylated interferon-α2b and ribavirin to Japanese patients with HCV-1b IL28B rs8099917 TT.

scientific article published on 5 November 2013

Telaprevir with peginterferon and ribavirin for treatment-naive patients chronically infected with HCV of genotype 1 in Japan

scientific article published on 7 August 2011

Telaprevir, peginterferon and ribavirin therapy for chronic hepatitis C

scientific article published in December 2015

Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals

scientific article

Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production

scientific article published on 29 August 2005

Tetrahydrobiopterin improves coronary endothelial function, but does not prevent coronary spasm in patients with vasospastic angina

scientific article

The Association between Glyceraldehyde-Derived Advanced Glycation End-Products and Colorectal Cancer Risk

scientific article published on 24 September 2015

The Clinical Usefulness of the PillCam Progress Indicator for Route Selection in Double Balloon Endoscopy

scientific article published on 10 January 2019

The Evaluation of Esophageal Motility Using Infusion Manometry with a Trans-nasal Endoscope: A Preliminary Study

scientific article published on 06 December 2019

The Patient-Related Burden of Pegylated-Interferon-α Therapy and Adverse Events among Patients with Viral Hepatitis C in Japan

scientific article published on 21 April 2014

The Role of Lipids in Hepatocellular Carcinoma

scientific article published on 31 October 2019

The Time Course of Dynamic Computed Tomographic Appearance of Radiation Injury to the Cirrhotic Liver Following Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma

scientific article published on 11 June 2015

The Water‐Soluble Extract from Cultured Medium of Ganoderma lucidum (Reishi) Mycelia (Designated as MAK) Ameliorates Murine Colitis Induced by Trinitrobenzene Sulphonic Acid ⬇️

scientific article published on 01 November 2011

The association between serum cytokine and chemokine levels and antiviral response by entecavir treatment in chronic hepatitis B patients

scientific article

The association of insomnia with gastroesophageal reflux symptoms in biopsy-proven nonalcoholic fatty liver disease.

scientific article

The combination of elbasvir and grazoprevir for the treatment of chronic HCV infection in Japanese patients: a randomized phase II/III study

scientific article

The diagnosis of hepatocellular carcinoma determined by pattern of AFP bands separated by Con A affinity electrophoresis

scientific article published on 01 August 1994

The effect of Helicobacter pylori eradication therapy on gastric ulcer healing after endoscopic mucosal resection

scientific article published in April 2006

The effect of respiratory-gated positron emission tomography/computed tomography in patients with pancreatic cancer

scientific article published in January 2014

The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.

scientific article published on April 2006

The first Japanese case of COACH syndrome

scientific article

The impact of interferon-free direct-acting antivirals on clinical outcome after curative treatment for hepatitis C virus-associated hepatocellular carcinoma; comparison with interferon-based therapy

scientific article published on 19 November 2018

The long-term outcome of patients with bleeding gastric varices after balloon-occluded retrograde transvenous obliteration

scientific article published on 24 August 2007

The nicorandil-induced vasodilation in humans is inhibited by miconazole

scientific article

The novel cutoff points for the FIB4 index categorized by age increase the diagnostic accuracy in NAFLD: a multi-center study

scientific article published on 09 May 2018

The number of criminal prosecutions against physicians due to medical negligence is on the rise in Japan

scientific article published on 01 January 2008

The practical management of chronic hepatitis C infection in Japan - dual therapy of daclatasvir + asunaprevir

scientific article published on 12 December 2016

The promoter methylation status of the DNA repair gene O6-methylguanine-DNA methyltransferase in ulcerative colitis.

scientific article

The relationship between HBcrAg and HBV reinfection in HBV related post-liver transplantation patients

scientific article published on 15 July 2016

The retrospective analysis of the histological course by use of GPT integration value in anti HBe positive cases with abnormal GPT

scientific article published on 01 April 1988

The risk of transient postprandial oxyhypoglycemia in nonalcoholic fatty liver disease

scientific article published on 28 June 2016

The risks of hepatocellular carcinoma development after HCV eradication are similar between patients treated with peg-interferon plus ribavirin and direct-acting antiviral therapy.

scientific article published on 10 August 2017

The roles of H. pylori infection and K-ras gene mutation in gastric carcinogenesis

scientific article

The utility of a novel colonoscope with retroflexion for colorectal endoscopic submucosal dissection

Therapeutic effect of repeated natural killer T cell stimulation in mouse cholangitis complicated by colitis

scientific article published on 01 October 2005

Therapeutic strategy for colorectal laterally spreading tumor

scientific article published on 01 July 2009

Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices

scientific article

Three Children Treated with Direct-acting Antivirals for Chronic Hepatitis C Virus Genotype 1b Infection

scientific article published on 06 December 2019

Three patients treated with daclatasvir and asunaprevir for recurrent hepatitis C after liver transplantation: Case report

scientific article published on 6 October 2015

Three patients treated with sofosbuvir plus ledipasvir for recurrent hepatitis C after liver transplantation

scientific article published on 21 February 2017

Thromboxane A2 synthase inhibitors prevent production of infectious hepatitis C virus in mice with humanized livers

scientific article published on 16 May 2013

Time course of histological changes in patients with a sustained biochemical and virological response to interferon-α therapy for chronic hepatitis C virus infection ⬇️

scientific article published on July 1, 1997

Timing of radiological improvement after steroid therapy in patients with autoimmune pancreatitis

scientific article published on 26 March 2014

Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.

scientific article published on 28 November 2011

Towards safer and appropriate application of endoscopic submucosal dissection for T1 colorectal carcinoma as total excisional biopsy: future perspectives

scientific article published on 16 October 2014

Transarterial infusion chemotherapy using cisplatin-lipiodol suspension with or without embolization for unresectable hepatocellular carcinoma

scientific article published on 15 May 2009

Transarterial therapy of hepatocellular carcinoma fed by the right renal capsular artery

scientific article published in March 2014

Transcatheter chemoembolization for unresectable hepatocellular carcinoma and comparison of five staging systems

scientific article published on 28 September 2010

Treatment of HCV patients on hemodialysis with daclatasvir and asunaprevir

scientific article published on 19 August 2016

Treatment of chronic hepatitis B with nucleos(t)ide analogues

scientific article published on 19 December 2011

Treatment of chronic hepatitis C virus infection in Japan: update on therapy and guidelines

scientific article published on 28 November 2012

Treatment of functional dyspepsia with serotonin agonists: a meta-analysis of randomized controlled trials

scientific article

Treatment of hepatic amyloid light-chain amyloidosis with bortezomib and dexamethasone in a liver transplant patient.

scientific article published on 18 December 2014

Treatment outcomes after splenectomy with gastric devascularization or balloon-occluded retrograde transvenous obliteration for gastric varices: a propensity score-weighted analysis from a single institution

scientific article published on 12 June 2020

Treatment strategy for early hepatocellular carcinomas: comparison of radiofrequency ablation with or without transcatheter arterial chemoembolization and surgical resection

scientific article published in July 2011

Treatments of chronic hepatitis B aiming to HBs seroclearance

scientific article published on December 2015

Trend in Japanese malpractice litigation involving gastrointestinal endoscopy

scientific article published on 01 January 2009

Trends in Hepatic Functional Reserve of Patients with Hepatocellular Carcinoma Treated with Tyrosine Kinase Inhibitors

scientific article published on 24 July 2020

Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma

scientific article published on 01 May 2020

Two Cases of Severe Ulcerative Colitis with Colonic Dilatation Resolved with Tacrolimus Therapy

scientific article published on May 2015

Two patients treated with pegylated interferon/ribavirin/telaprevir triple therapy for recurrent hepatitis C after living donor liver transplantation.

scientific article published on 17 February 2014

Type 2 diabetes mellitus is associated with the fibrosis severity in patients with nonalcoholic fatty liver disease in a large retrospective cohort of Japanese patients

scientific article

Ubiquitin-interacting motifs of Epsin are involved in the regulation of insulin-dependent endocytosis

scientific article

Ultradeep sequencing study of chronic hepatitis C virus genotype 1 infection in patients treated with daclatasvir, peginterferon, and ribavirin.

scientific article

Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes

scientific article

Unique reciprocal changes of hepatocellular membrane transporter expression and fluidity in rats with selective biliary obstruction

scientific article

Upper limit of normal serum alanine aminotransferase levels in Japanese subjects

scientific article published on 17 February 2014

Upstroke Time Is a Useful Vascular Marker for Detecting Patients With Coronary Artery Disease Among Subjects With Normal Ankle-Brachial Index

scientific article published on 26 November 2020

Use of 4-Fr versus 6-Fr Nasobiliary Catheter for Biliary Drainage: A Prospective, Multicenter, Randomized, Controlled Study.

scientific article

Use of Mac-2 binding protein as a biomarker for nonalcoholic fatty liver disease diagnosis

scientific article published on 16 August 2017

Use of anticoagulants increases risk of bleeding after colorectal endoscopic submucosal dissection.

scientific article

Use of entecavir to prevent hepatitis B virus reactivation during cytotoxic chemotherapy for solid malignancy

scientific article

Useful condition of chromoendoscopy with indigo carmine and acetic acid for identifying a demarcation line prior to endoscopic submucosal dissection for early gastric cancer

scientific article

Usefulness and limitations of transabdominal ultrasonography for detecting small-bowel tumors

scientific article published on 01 January 2009

Usefulness and safety of SB knife Jr in endoscopic submucosal dissection for colorectal tumors

scientific article published in May 2012

Usefulness of EUS with double-balloon enteroscopy for diagnosis of small-bowel diseases

scientific article published in March 2007

Usefulness of combining gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging and contrast-enhanced ultrasound for diagnosing the macroscopic classification of small hepatocellular carcinoma

scientific article published on 3 June 2015

Usefulness of endoscopic ultrasonography in determining the depth of invasion and indication for endoscopic treatment of early gastric cancer

scientific article published on April 2009

Usefulness of flow-mediated dilation of the brachial artery and/or the intima-media thickness of the carotid artery in predicting coronary narrowing in patients suspected of having coronary artery disease ⬇️

scientific article published on November 15, 2001

Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology

scientific article published on 28 January 2017

Usefulness of linked color imaging in the early detection of superficial esophageal squamous cell carcinomas

scientific article published on 23 May 2020

Usefulness of multi-detector row computed tomography for management of duodenal varices by emergency balloon-occluded retrograde transvenous obliteration

scientific article

Usefulness of peroral cholangioscopy in the differential diagnosis of IgG4-related sclerosing cholangitis and extrahepatic cholangiocarcinoma: a single-center retrospective study

scientific article published on 24 August 2020

Utility of controlled attenuation parameter measurement for assessing liver steatosis in Japanese patients with chronic liver diseases

scientific article published on 02 April 2013

Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population

scientific article

Value of cytodiagnosis using endoscopic nasopancreatic drainage for early diagnosis of pancreatic cancer: establishing a new method for the early detection of pancreatic carcinoma in situ

scientific article published on 01 May 2012

Vaniprevir plus peginterferon alfa-2b and ribavirin in treatment-experienced Japanese patients with hepatitis C virus genotype 1 (GT1b) infection: Phase 3 studies

scientific article published on 02 March 2016

Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations

scientific article published on 26 September 2010

Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers

scientific journal article

Vascular Function and Intima-media Thickness of a Leg Artery in Peripheral Artery Disease: A Comparison of Buerger Disease and Atherosclerotic Peripheral Artery Disease

scientific article published on 09 May 2016

Vascular endothelial growth factor C stimulates progression of human gastric cancer via both autocrine and paracrine mechanisms.

scientific article

Vascular function and circulating progenitor cells in thromboangitis obliterans (Buerger's disease) and atherosclerosis obliterans

scientific article published on 29 November 2010

Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities

scientific article published on 01 January 2005

Vascular function is further impaired in subjects aged 80 years or older

scientific article published on 08 April 2020

Virological escape in HCV genotype-1-infected patients receiving daclatasvir plus ribavirin and peginterferon alfa-2a or alfa-2b

scientific article published on 22 January 2014

Virological response and safety of 24‐week telaprevir alone in Japanese patients infected with hepatitis C virus subtype 1b ⬇️

scientific article published on July 13, 2012

Vitamin D supplementation on IFN-based therapy

scientific article published on December 2015

Volume Elastic Modulus, Vascular Function, and Vascular Structure in Patients with Cardiovascular Risk Factors

scientific article published on 23 October 2020

Warning for unprincipled colorectal endoscopic submucosal dissection: accurate diagnosis and reasonable treatment strategy

scientific article published on 20 December 2012

Whole genome sequencing discriminates hepatocellular carcinoma with intrahepatic metastasis from multi-centric tumors

scientific article

Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity

scientific article published on 30 January 2015

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

scientific article

Will there be an HCV meeting in 2020? Summary of the 17th international meeting on hepatitis C virus and related viruses

scientific article published on 24 May 2011

Wisteria floribunda agglutinin positive Mac-2-binding protein level increases in patients with acute liver injury

scientific article

Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts the development of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease

scientific article published on 7 January 2018

Zoledronic acid delays disease progression of bone metastases from hepatocellular carcinoma

scientific article published on 7 October 2010

[A case of advanced hepatocellular carcinoma with lung, brain and lymph node metastases recurred 8 years after hepatectomy successfully treated by operation, radiation and systemic chemotherapy using S-1/CDDP]

scientific article published on 01 August 2012

[A case of clonorchiasis complicated with the expansion of liver cyst]

scientific article published on 01 March 2013

[A case of diversion colitis successfully treated with 5-aminosalicylic acid]

[A case of pancreatic solid-pseudopapillary tumor without cystic component in an elderly man]

scientific article published on 01 November 2006

[A case report of anaphylactoid purpura with acute abdominal pain secondary to trauma caused by traffic accident]

scientific article published on 01 April 2008

[A case report of hepatocellular carcinoma with metastases to the lip, stomach, and colorectum]

[Angiomyolipoma]

scientific article published on 01 February 2010

[Application of colonoscopy for patients with colonic adenoma--evaluation of the treatment efficacy and follow-up study]

scientific article published on 01 February 2007

[Case of double cancer of the liver, cholangiocarcinoma and hepatocellular carcinoma detected in a patient with hepatitis C 13 years after diminution of HCV-RNA by interferon treatment]

scientific article published on 01 May 2009

[Changing concept of liver diseases in the era of hepatitis virus control]

scientific article published on 01 January 2018

[Characteristics of H. pylori-negative gastric cancer]

scientific article published on 01 October 2012

[Classification of the bleeding pattern in colonic diverticulum is useful to predict the risk of bleeding or re-bleeding after endoscopic treatment]

scientific article published on 01 March 2012

[Current status and future prospects of endoscopic treatment for rectal cancer]

scientific article published on 01 January 2020

[Detection of hepatitis B core antibody (including IgM and IgA class antibodies)]

scientific article published on 01 August 2004

[Diagnosis and treatment for benign small bowel tumor]

scientific article published on 01 July 2008

[Differential diagnosis of GERD]

scientific article published on 01 August 2004

[Differential diagnosis of ulcerative colitis and Crohn's disease]

scientific article published on 01 February 2012

[Endoscopic diagnosis of early gastric cancer]

scientific article published on 01 October 2012

[Endoscopic treatment for early colorectal carcinoma: EMR or ESD?]

scientific article published on 01 April 2011

[Genetic factors in HLA-DP associated with pathology, therapeutic outcome, and prognosis of chronic hepatitis B]

[HCV persistence and HLA-DQB1]

[HCV replication animal model]

scientific article published on 01 May 2011

[Hepatic artery pseudoaneurysm after endoscopic biliary stenting for pancreatic cancer]

[Hepatitis C virus RNA and nucleic acid testing].

scientific article

[Hepatitis C]

scientific article published on 01 January 2002

[Hepatitis D virus infection]

scientific article published on 01 February 2003

[Indication and actual status of endoscopic submucosal dissection for colorectal tumors -present status and future perspective]

scientific article published on 01 April 2015

[Malignant phyllodes tumor metastatic to the pancreas: a case report]

scientific article published on 01 May 2012

[Management of diagnosis for biliary tract cancer]

scientific article published on 01 January 2006

[Management of treatment in nodule-aggregating colorectal cancer]

scientific article published on 01 September 2003

[Mechanism of HCV cell entry mediated by envelope and receptor proteins]

scientific article published on 01 July 2004

[Multiple hepatic sclerosed hemangiomas that are difficult to diagnose preoperatively:a case report]

scientific article published on 01 January 2018

[Practice of screening tests for a group of patients with a high risk of developing liver cancer]

scientific article published on 01 January 2008

[Q & A. Intra-hepatic multiple nodules developing following treatment of hepatic calculi].

scientific article published in December 2011

[Recent progress in the study of genetic variants associated with liver diseases]

scientific article published on 01 September 2013

[The 44th Scientific Meeting: Perspectives of Internal Medicine: Virology for Physician ∼Recent Advance in Viral Infection and Treatment∼: 3. Common Viral Infectious Diseases; Viral Hepatitis: 2) Hepatitis C]

scientific article published on 01 March 2017

[The 44th Scientific Meeting: Perspectives of Internal Medicine: Virology for Physician ∼Recent Advance in Viral Infection and Treatment∼: 5. Conclusion]

scientific article published on 01 March 2017

[The analysis of the recurrence ulcer after H. pylori eradication]

scientific article published on 01 February 2002

[The current status and prospect of treatment of hepatitis C. A discussion]

scientific article published on 01 April 2009

[Treatment of colorectal carcinoma having submucosal invasion]

scientific article published on 01 September 2003

eVIDENCE: a practical variant filtering for low-frequency variants detection in cell-free DNA

scientific article published on 22 October 2019

mTOR and PDGF pathway blockade inhibits liver metastasis of colorectal cancer by modulating the tumor microenvironment

scientific article

miR-135a-5p-mediated downregulation of protein tyrosine phosphatase receptor delta is a candidate driver of HCV-associated hepatocarcinogenesis

scientific article

p53 Codon 72 polymorphism in gastric cancer susceptibility in patients with Helicobacter pylori-associated chronic gastritis

scientific article

p53 expression, K-ras gene mutation and microsatellite instability in gastric B-cell lymphomas

scientific article published in September 2003

List of works by Kazuaki Chayama

<em>In vitro</em> analysis of hepatic stellate cell activation influenced by transmembrane 6 superfamily 2 polymorphism

A Comparison of Adrenalectomy and Eplerenone on Vascular Function in Patients with Aldosterone-producing Adenoma

A Cost-Effectiveness Analysis of Glecaprevir/Pibrentasvir Versus Existing Direct-Acting Antivirals to Treat Chronic Hepatitis C in Japan

A Data Mining-based Prognostic Algorithm for NAFLD-related Hepatoma Patients: A Nationwide Study by the Japan Study Group of NAFLD.

A MAVS/TICAM-1-independent interferon-inducing pathway contributes to regulation of hepatitis B virus replication in the mouse hydrodynamic injection model.

A Patient with CTLA-4 Haploinsufficiency Presenting Gastric Cancer

A case of Crohn's disease with hydronephrosis caused by ureteropelvic junction obstruction.

A case of advanced HCC treated with lenvatinib after hepatic arterial infusion chemotherapy combined with radiation therapy treatment for portal vein tumor thrombosis in the main trunk

A case of chronic hepatitis C with pancreas divisum and acute pancreatitis during combination treatment with telaprevir/peginterferon/ribavirin

A case of congenital absence of the portal vein

A case of fulminant hepatic failure caused by hepatitis E virus

A case of intrahepatic cholangiocarcinoma with liver cirrhosis presenting atypical images

A case of large cell neuroendocrine carcinoma of the stomach with multiple liver metastases

A case of latent primary biliary cirrhosis

A case of multiple hepatic peribiliary cysts which contributed to the obstructive jaundice and led to liver failure at the young man with von Recklinghausen's disease

A case of primary malignant melanoma of the esophagus with a widely expanded surface area

A case of syndrome of inappropriate secretion of antidiuretic hormone following transarterial embolization with cisplatin

A case with life-threatening secondary sclerosing cholangitis caused by nivolumab

A classification system of echogenicity for gastrointestinal neoplasms

A combination of the Helicobacter pylori stool antigen test and urea breath test is useful for clinical evaluation of eradication therapy: a multicenter study

A comparison of 4-Fr with 5-Fr endoscopic nasopancreatic drainage catheters: A randomized, controlled trial

A comparison of low-dose and standard-dose oral estrogen on forearm endothelial function in early postmenopausal women

A computer system to be used with laser-based endoscopy for quantitative diagnosis of early gastric cancer

A first case of hepatic angiosarcoma treated with recombinant interleukin-2.

A frameshift mutation of beta subunit of epithelial sodium channel in a case of isolated Liddle syndrome

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians

A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region

A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population

A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1

A huge metastatic liver tumor from leiomyosarcoma of the inferior vena cava: report of a case

A low-calorie diet improves endothelium-dependent vasodilation in obese patients with essential hypertension

A multicenter, open-label, dose-ranging study to exploratively evaluate the efficacy, safety, and dose-response of tolvaptan in patients with decompensated liver cirrhosis

A multivariate analysis of risk factors for hepatocellular carcinogenesis: A prospective observation of 795 patients with viral and alcoholic cirrhosis ⬇️

A nationwide survey on non-B, non-C hepatocellular carcinoma in Japan: 2011-2015 update

A nonsynonymous polymorphism in semaphorin 3A as a risk factor for human unexplained cardiac arrest with documented ventricular fibrillation

A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections.

A novel noninvasive and simple method for assessment of endothelial function: enclosed zone flow-mediated vasodilation (ezFMD) using an oscillation amplitude measurement.

A novel noninvasive diagnostic method for nonalcoholic steatohepatitis using two glycobiomarkers

A nuclear receptor ligand down-regulates cytosolic phospholipase A2 expression to reduce bile acid-induced cyclooxygenase 2 activity in cholangiocytes: implications of anticarcinogenic action of farnesoid X receptor agonists

A nuclear receptor-mediated choleretic action of fibrates is associated with enhanced canalicular membrane fluidity and transporter activity mediating bile acid-independent bile secretion

A phase III study of the efficacy and safety of meropenem in patients with febrile neutropenia

A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.

A proposed system for the nomenclature of hepatitis C viral genotypes

A randomized controlled trial of interferon-alpha in patients with cirrhosis caused by 2a/2b genotype hepatitis C virus ⬇️

A randomized phase II trial of intra-arterial chemotherapy using SM-11355 (Miriplatin) for hepatocellular carcinoma

A randomized trial of daclatasvir with peginterferon alfa-2b and ribavirin for HCV genotype 1 infection

A randomized, controlled study of peginterferon lambda-1a/ribavirin ± daclatasvir for hepatitis C virus genotype 2 or 3.

A second attack of cholestasis associated with erythropoietic protoporphyria was successfully treated by plasma exchange and blood transfusion

A simple clinical scoring system using ferritin, fasting insulin, and type IV collagen 7S for predicting steatohepatitis in nonalcoholic fatty liver disease

A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.

A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer

A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer

A spontaneous Type 1 electrocardiogram pattern in lead V2 is an independent predictor of ventricular fibrillation in Brugada syndrome

A translational study of resistance emergence using sequential direct-acting antiviral agents for hepatitis C using ultra-deep sequencing.

A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers

A watch-and-wait policy versus rituximab-combined chemotherapy in Japanese patients with intestinal follicular lymphoma

A water-soluble extract from culture medium of Ganoderma lucidum mycelia suppresses the development of colorectal adenomas

ADH1B and ALDH2 are associated with metachronous SCC after endoscopic submucosal dissection of esophageal squamous cell carcinoma

ADIPOQ polymorphisms are associated with insulin resistance in Japanese women

AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl(4).

Abatacept treatment for patients with severe acute hepatitis caused by hepatitis B virus infection - Pilot study

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

Ablation of the bach1 gene leads to the suppression of atherosclerosis in bach1 and apolipoprotein E double knockout mice

Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice.

Accumulation of refractory factors for pegylated interferon plus ribavirin therapy in older female patients with chronic hepatitis C.

Achievement of sustained viral response after switching treatment from pegylated interferon α-2b to α-2a and ribavirin in patients with recurrence of hepatitis C virus genotype 1 infection after liver transplantation: a case report.

Activation of Akt is associated with poor prognosis and chemotherapeutic resistance in pediatric B‐precursor acute lymphoblastic leukemia ⬇️

Acute HBV infection in humanized chimeric mice has multiphasic viral kinetics

Acute moderate-intensity exercise induces vasodilation through an increase in nitric oxide bioavailiability in humans

Adoptive immunotherapy with liver allograft–derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice

Adrenomedullin causes coronary vasodilation in humans: effects of inhibition of nitric oxide synthesis

Advanced colorectal carcinoma smaller than 10 mm in maximum diameter with special reference to clinicopathologic and molecular features: a report of 3 cases

Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells

Advanced liver fibrosis effects on the response to sofosbuvir-based antiviral therapies for chronic hepatitis C

Advanced method for evaluation of gastric cancer risk by serum markers: determination of true low-risk subjects for gastric neoplasm

Advances of an internal treatment for early colorectal carcinoma

Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer

Advantages of endoscopic submucosal dissection versus endoscopic oblique aspiration mucosectomy for superficial esophageal tumors

Aged garlic extract has potential suppressive effect on colorectal adenomas in humans