List of works - Christopher M Overall

A high-stringency blueprint of the human proteome

scientific article published on 16 October 2020

A myoglobin variant with a polar substitution in a conserved hydrophobic cluster in the heme binding pocket ⬇️

scientific article published on August 15, 1997

Advances in Identifying and Characterizing the Human Proteome

scientific article published on 01 December 2019

An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient

scientific article published on 28 January 2019

C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.

scientific article published on 20 June 2018

Deep Profiling of the Cleavage Specificity and Human Substrates of Snake Venom Metalloprotease HF3 by Proteomic Identification of Cleavage Site Specificity (PICS) Using Proteome Derived Peptide Libraries and Terminal Amine Isotopic Labeling of Subst

scientific article published on 08 August 2019

Discovery of a proteolytic flagellin family in diverse bacterial phyla that assembles enzymatically active flagella

scientific article published on 12 September 2017

Expression of matrix metalloproteinases (MMP-1 and -2) and their inhibitors (TIMP-1, -2 and -3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis ⬇️

scientific article published on June 1, 1998

Global Profiling of Proteolysis from the Mitochondrial Amino Terminome during Early Intrinsic Apoptosis Prior to Caspase-3 Activation

scientific article published on 29 October 2018

Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction.

scientific article

Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases

scientific article published on 04 January 2019

Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis

scientific article published on 19 June 2020

Launching the C-HPP pilot project for functional characterization of identified proteins with no known function

scientific article published on 29 November 2018

MMP8 increases tongue carcinoma cell-cell adhesion and diminishes migration via cleavage of anti-adhesive FXYD5

scientific article published on 31 May 2021

Master Sculptor at Work: Enteropathogenic Escherichia coli Infection Uniquely Modifies Mitochondrial Proteolysis during Its Control of Human Cell Death

scientific article published on 02 June 2020

Matrix metalloproteinases in the CNS: interferons get nervous

scientific article published on 04 June 2019

Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions

scientific article published on 18 July 2019

Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project

scientific article published on 23 August 2018

Progress on Identifying and Characterizing the Human Proteome: 2019 Metrics from the HUPO Human Proteome Project

scientific article published on 13 September 2019

Proteomic and N-Terminomic TAILS Analyses of Human Alveolar Bone Proteins: Improved Protein Extraction Methodology and LysargiNase Digestion Strategies Increase Proteome Coverage and Missing Protein Identification

scientific article published on 25 October 2019

Quantitative proteomics and terminomics to elucidate the role of ubiquitination and proteolysis in adaptive immunity

scientific article

Sharpening Host Defenses during Infection: Proteases Cut to the Chase

scientific article published on 8 February 2017

The HUPO High-Stringency Inventory of Humanity's Shared Human Proteome Revealed

scientific article published on 19 October 2020

The Human Proteome: 90% in the Light, 10% on the Dark Side

scientific article published on 01 December 2020

The Involvement of the Fibronectin Type II-like Modules of Human Gelatinase A in Cell Surface Localization and Activation ⬇️

scientific article published on August 7, 1998

TopFIND 2.0--linking protein termini with proteolytic processing and modifications altering protein function ⬇️

scientific article published on November 18, 2011

Toward Completion of the Human Proteome Parts List: Progress Uncovering Proteins That Are Missing or Have Unknown Function and Developing Analytical Methods

scientific article published on 01 December 2018

List of works by Christopher M Overall