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List of works by Antonio Oliver

A Genome-Based Model to Predict the Virulence of Pseudomonas aeruginosa Isolates

scientific article published on 25 August 2020

A Multinational, Preregistered Cohort Study of β-Lactam/β-Lactamase Inhibitor Combinations for Treatment of Bloodstream Infections Due to Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae

scientific article published on 02 May 2016

A Predictive Model of Mortality in Patients With Bloodstream Infections due to Carbapenemase-Producing Enterobacteriaceae

scientific article published on October 2016

A Standard Numbering Scheme for Class C β-Lactamases

scientific article published on 21 February 2020

A large sustained endemic outbreak of multiresistant Pseudomonas aeruginosa: a new epidemiological scenario for nosocomial acquisition.

scientific article

A randomized trial of intravenous glutamine supplementation in trauma ICU patients

scientific article published on 21 February 2014

A trade-off between oxidative stress resistance and DNA repair plays a role in the evolution of elevated mutation rates in bacteria.

scientific article published on 27 February 2013

Activity of Ceftazidime-Avibactam against Clinical and Isogenic Laboratory Pseudomonas aeruginosa Isolates Expressing Combinations of Most Relevant β-Lactam Resistance Mechanisms

scientific article published on August 2016

Activity of Imipenem-Relebactam against a Large Collection of Pseudomonas aeruginosa Clinical Isolates and Isogenic β-Lactam-Resistant Mutants

scientific article published on 27 January 2020

Activity of a new antipseudomonal cephalosporin, CXA-101 (FR264205), against carbapenem-resistant and multidrug-resistant Pseudomonas aeruginosa clinical strains

scientific article

Activity of a new cephalosporin, CXA-101 (FR264205), against beta-lactam-resistant Pseudomonas aeruginosa mutants selected in vitro and after antipseudomonal treatment of intensive care unit patients

scientific article published on 19 January 2010

Activity of ceftazidime-avibactam against multidrug-resistance Enterobacteriaceae expressing combined mechanisms of resistance.

scientific article

Activity of mammalian peptidoglycan-targeting immunity against Pseudomonas aeruginosa

scientific article published on 01 April 2020

Adding insult to injury: mechanistic basis for how AmpC mutations allow Pseudomonas aeruginosa to accelerate cephalosporin hydrolysis and evade avibactam

scientific article published on 13 July 2020

Alterations of OprD in carbapenem-intermediate and -susceptible strains of Pseudomonas aeruginosa isolated from patients with bacteremia in a Spanish multicenter study.

scientific article published on 30 January 2012

Anti-biofilm and resistance suppression activities of CXA-101 against chronic respiratory infection phenotypes of Pseudomonas aeruginosa strain PAO1.

scientific article published on 30 April 2010

Antibiotic resistance and population structure of cystic fibrosis Pseudomonas aeruginosa isolates from a Spanish multi-centre study.

scientific article

Antibiotic treatment of biofilm infections

scientific article published on April 2017

Antimicrobial stewardship in Spain: Programs for Optimizing the use of Antibiotics (PROA) in Spanish hospitals

article

Antimicrobial stewardship programs: a public health priority in Spain. The SEIMC-REIPI initiative.

scientific article published in September 2013

Assessing the emergence of resistance: the absence of biological cost in vivo may compromise fosfomycin treatments for P. aeruginosa infections

scientific article

Association between Pseudomonas aeruginosa O-antigen serotypes, resistance profiles and high-risk clones: results from a Spanish nationwide survey

scientific article published in 2019

Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants

scientific article published on 2 February 2009

Bacterial virulence regulation through soluble peptidoglycan fragments sensing and response: knowledge gaps and therapeutic potential

scientific article published in 2023

Benefit of having multiple ampD genes for acquiring beta-lactam resistance without losing fitness and virulence in Pseudomonas aeruginosa

scientific article published on 21 July 2008

Beta-lactam resistance response triggered by inactivation of a nonessential penicillin-binding protein

scientific article

Biological markers of Pseudomonas aeruginosa epidemic high-risk clones

scientific article published on 26 August 2013

Breakpoints for carbapenemase-producing Enterobacteriaceae: is the problem solved?

scientific article published on December 2014

Bronchopulmonary infection-colonization patterns in Spanish cystic fibrosis patients: Results from a national multicenter study.

scientific article published on 28 September 2015

CTX-M-10 linked to a phage-related element is widely disseminated among Enterobacteriaceae in a Spanish hospital

scientific article published on April 2005

Carbapenemase-producing Pseudomonas aeruginosa in Spain: interregional dissemination of the high risk-clones ST175 and ST244 carrying blaVIM-2, blaVIM-1, blaIMP-8, blaVIM-20 and blaKPC-2

scientific article published on 22 May 2020

Ceftazidime, carbapenems, or piperacillin-tazobactam as single definitive therapy for Pseudomonas aeruginosa bloodstream infection - a multi-site retrospective study

scientific article published on 17 July 2019

Ceftolozane/tazobactam for the treatment of multidrug resistant Pseudomonas aeruginosa: experience from the Balearic Islands

scientific article published on 23 August 2018

Challenges for accurate susceptibility testing, detection and interpretation of β-lactam resistance phenotypes in Pseudomonas aeruginosa: results from a Spanish multicentre study.

scientific article published on 9 November 2012

Challenging Antimicrobial Susceptibility and Evolution of Resistance (OXA-681) during Treatment of a Long-Term Nosocomial Infection Caused by a Pseudomonas aeruginosa ST175 Clone

scientific article published on 23 September 2019

Characterization and molecular epidemiology of ESBL in Escherichia coli and Klebsiella pneumoniae in 11 Spanish hospitals (2004)

scientific article published in August 2008

Characterization of AmpC β-lactamase mutations of extensively drug-resistant Pseudomonas aeruginosa isolates that develop resistance to ceftolozane/tazobactam during therapy

scientific article published on 03 March 2020

Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia

scientific article published on 27 March 2019

Characterization of a large outbreak by CTX-M-1-producing Klebsiella pneumoniae and mechanisms leading to in vivo carbapenem resistance development

scientific article published on August 2006

Characterization of a novel IMP-28 metallo-β-lactamase from a Spanish Klebsiella oxytoca clinical isolate.

scientific article published on 5 June 2012

Characterization of a novel Zn²⁺-dependent intrinsic imipenemase from Pseudomonas aeruginosa

scientific journal article

Characterization of plasmids encoding blaESBL and surrounding genes in Spanish clinical isolates of Escherichia coli and Klebsiella pneumoniae.

scientific article published on 6 November 2008

Characterization of the GO system of Pseudomonas aeruginosa

scientific journal article

Characterization of the new AmpC β-lactamase FOX-8 reveals a single mutation, Phe313Leu, located in the R2 loop that affects ceftazidime hydrolysis

scientific article published on 22 July 2013

Chronic Pseudomonas aeruginosa infection in chronic obstructive pulmonary disease

scientific article published on 01 December 2008

Chronic respiratory infections by mucoid carbapenemase-producing Pseudomonas aeruginosa strains, a new potential public health problem

scientific article published on 7 April 2008

Clinically relevant epithelial lining fluid concentrations of meropenem with ciprofloxacin provide synergistic killing and resistance suppression of hypermutable Pseudomonas aeruginosa in a dynamic biofilm model

scientific article published on 04 May 2020

Clonal dissemination, emergence of mutator lineages and antibiotic resistance evolution in Pseudomonas aeruginosa cystic fibrosis chronic lung infection.

scientific article

Coevolution with viruses drives the evolution of bacterial mutation rates.

scientific article

Colistin plus meropenem combination is synergistic in vitro against extensively drug-resistant Pseudomonas aeruginosa, including high-risk clones

scientific article published on 30 May 2019

Colonisation and infection due to Enterobacteriaceae producing plasmid-mediated AmpC β-lactamases

scientific article

Community infections caused by extended-spectrum beta-lactamase-producing Escherichia coli.

scientific article published in September 2008

Community-onset bacteremia due to extended-spectrum beta-lactamase-producing Escherichia coli: risk factors and prognosis

scientific article

Comparative Analysis of Peptidoglycans From Pseudomonas aeruginosa Isolates Recovered From Chronic and Acute Infections

scientific article published on 27 August 2019

Comparison of Local Features from Two Spanish Hospitals Reveals Common and Specific Traits at Multiple Levels of the Molecular Epidemiology of Metallo-β-Lactamase-Producing Pseudomonas spp.

scientific article published in August 2014

Comparison of Predictors and Mortality Between Bloodstream Infections Caused by ESBL-Producing Escherichia coli and ESBL-Producing Klebsiella pneumoniae

scientific article

Comparison of local features from two Spanish hospitals reveals common and specific traits at multiple levels of the molecular epidemiology of metallo-β-lactamase-producing Pseudomonas spp.

scientific article published on 3 February 2014

Comprehensive clinical and epidemiological assessment of colonisation and infection due to carbapenemase-producing Enterobacteriaceae in Spain

scientific article

Consolidation of a Staphylococcus aureus multiresistant clone not related to the Iberian in a hospital from Mallorca

scientific article

Corrigendum to ``Emergence of high level and stable metronidazole resistance in Clostridioides difficile'' [International Journal of Antimicrobial Agents Vol. 55 (2020) 5830]

scientific article published on 04 May 2020

Corrigendum to “Extended-spectrum β-lactamase-producing Escherichia coli in Spain belong to a large variety of multilocus sequence typing types, including ST10 complex/A, ST23 complex/A and ST131/B2” [Int. J. Antimicrob. Agents 34 (2009) 173–1

article

Deciphering the Resistome of the Widespread Pseudomonas aeruginosa Sequence Type 175 International High-Risk Clone through Whole-Genome Sequencing.

scientific article published on 10 October 2016

Deciphering β-lactamase-independent β-lactam resistance evolution trajectories in Pseudomonas aeruginosa

scientific article published on 01 December 2018

Detection and susceptibility testing of hypermutable Pseudomonas aeruginosa strains with the Etest and disk diffusion

scientific article published on July 2004

Determining β-lactam exposure threshold to suppress resistance development in Gram-negative bacteria

scientific article published on 31 January 2017

Development and validation of the INCREMENT-ESBL predictive score for mortality in patients with bloodstream infections due to extended-spectrum-β-lactamase-producing Enterobacteriaceae.

scientific article published on 6 January 2017

Development of antibiotic resistance and up-regulation of the antimutator gene pfpI in mutator Pseudomonas aeruginosa due to inactivation of two DNA oxidative repair genes (mutY, mutM).

scientific article

Distinct epidemiology and resistance mechanisms affecting ceftolozane/tazobactam in Pseudomonas aeruginosa isolates recovered from ICU patients in Spain and Portugal depicted by WGS

scientific article published on 25 October 2020

Diversity and regulation of intrinsic β-lactamases from non-fermenting and other Gram-negative opportunistic pathogens.

scientific article published on 22 September 2017

Draft Genome Sequence of Colistin-Only-Susceptible Pseudomonas aeruginosa Strain ST235, a Hypervirulent High-Risk Clone in Spain

scientific article

Draft Genome Sequence of VIM-2-Producing Multidrug-Resistant Pseudomonas aeruginosa ST175, an Epidemic High-Risk Clone.

scientific article published on March 2013

Draft Genome Sequence of the Quorum-Sensing and Biofilm-Producing Pseudomonas aeruginosa Strain Pae221, Belonging to the Epidemic High-Risk Clone Sequence Type 274.

scientific article published on 15 January 2015

Draft Genome Sequences of Four Pseudomonas aeruginosa Isolates Obtained from Patients with Chronic Obstructive Pulmonary Disease

scientific article published on 15 June 2017

Dynamics of mutator and antibiotic-resistant populations in a pharmacokinetic/pharmacodynamic model of Pseudomonas aeruginosa biofilm treatment.

scientific article

Effect of adequate single-drug vs combination antimicrobial therapy on mortality in Pseudomonas aeruginosa bloodstream infections: a post Hoc analysis of a prospective cohort.

scientific article published on 11 April 2013

Effect of appropriate combination therapy on mortality of patients with bloodstream infections due to carbapenemase-producing Enterobacteriaceae (INCREMENT): a retrospective cohort study

scientific article published on 21 April 2017

Effective inhibition of PBPs by cefepime and zidebactam in the presence of VIM-1 drives potent bactericidal activity against MBL-expressing Pseudomonas aeruginosa

scientific article published on 21 February 2020

Emergence of Resistance to Novel β-Lactam-β-Lactamase Inhibitor Combinations Due to Horizontally Acquired AmpC (FOX-4) in Pseudomonas aeruginosa Sequence Type 308

scientific article published on 20 December 2019

Emergence of high-level and stable metronidazole resistance in Clostridioides difficile

scientific article published on 21 November 2019

Empiric Therapy With Carbapenem-Sparing Regimens for Bloodstream Infections due to Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae: Results From the INCREMENT Cohort

scientific article published on 19 August 2017

Environmental microbiota represents a natural reservoir for dissemination of clinically relevant metallo-beta-lactamases

scientific article published on 22 August 2011

Epidemiological and clinical complexity of amoxicillin-clavulanate-resistant Escherichia coli.

scientific article published on May 2013

Epidemiology and Treatment of Multidrug-Resistant and Extensively Drug-Resistant Pseudomonas aeruginosa Infections

scientific article published on 28 August 2019

Epidemiology of extended-spectrum beta-lactamase-producing Enterobacter isolates in a Spanish hospital during a 12-year period

scientific article

Erratum for del Barrio-Tofiño et al., "Genomics and Susceptibility Profiles of Extensively Drug-Resistant Pseudomonas aeruginosa Isolates from Spain".

scientific article published on 21 December 2017

Ertapenem for the treatment of bloodstream infections due to ESBL-producing Enterobacteriaceae: a multinational pre-registered cohort study

scientific article published on 22 February 2016

Escherichia coli producing SHV-type extended-spectrum beta-lactamase is a significant cause of community-acquired infection.

scientific article published on 17 February 2009

Evaluation of Ceftolozane-Tazobactam in Combination with Meropenem against Pseudomonas aeruginosa ST175 in a Hollow-Fiber Infection Model.

scientific article published on 12 March 2018

Evaluation of Tobramycin and Ciprofloxacin as a Synergistic Combination Against Hypermutable Pseudomonas Aeruginosa Strains via Mechanism-Based Modelling

scientific article published on 12 September 2019

Evolution and adaptation in Pseudomonas aeruginosa biofilms driven by mismatch repair system-deficient mutators.

scientific article

Evolution of Pseudomonas aeruginosa Antimicrobial Resistance and Fitness under Low and High Mutation Rates.

scientific article published on 04 January 2016

Evolution of the Pseudomonas aeruginosa aminoglycoside mutational resistome in vitro and in the cystic fibrosis setting.

scientific article published on 5 February 2018

Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone

scientific article

Expression of toll-like receptors 2 and 4 is upregulated during hospital admission in traumatic patients: lack of correlation with blunted innate immune responses

scientific article published on 01 March 2010

Extended-spectrum beta-lactamase-producing Escherichia coli in Spain belong to a large variety of multilocus sequence typing types, including ST10 complex/A, ST23 complex/A and ST131/B2.

scientific article

From CLSI to EUCAST, a necessary step in Spanish laboratories

article

Genes encoding TEM-4, SHV-2, and CTX-M-10 extended-spectrum beta-lactamases are carried by multiple Klebsiella pneumoniae clones in a single hospital (Madrid, 1989 to 2000).

scientific article published on February 2002

Genetic and kinetic characterization of the novel AmpC β-lactamases DHA-6 and DHA-7. ⬇️

scientific article

Genetic markers of widespread extensively drug-resistant Pseudomonas aeruginosa high-risk clones.

scientific article published on 8 October 2012

Genomics and Susceptibility Profiles of Extensively Drug-Resistant (XDR) Pseudomonas aeruginosa from Spain.

scientific article published on 5 September 2017

Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains

scientific article

Geographical variation in therapy for bloodstream infections due to multidrug-resistant enterobacteriaceae: a post hoc analysis of the INCREMENT study.

scientific article published on 03 August 2017

High β-lactamase levels change the pharmacodynamics of β-lactam antibiotics in Pseudomonas aeruginosa biofilms

scientific article published on 22 October 2012

Higher MICs (>2 mg/L) Predict 30-Day Mortality in Patients With Lower Respiratory Tract Infections Caused by Multidrug- and Extensively Drug-Resistant Pseudomonas aeruginosa Treated With Ceftolozane/Tazobactam

scientific article published on 28 September 2019

Host and Pathogen Biomarkers for Severe Pseudomonas aeruginosa Infections

scientific article published on February 2017

Hypermutation and the preexistence of antibiotic-resistant Pseudomonas aeruginosa mutants: implications for susceptibility testing and treatment of chronic infections

scientific article

Hypermutation in Burkholderia cepacia complex is mediated by DNA mismatch repair inactivation and is highly prevalent in cystic fibrosis chronic respiratory infection

scientific article published on 28 August 2014

Hypermutation is a key factor in development of multiple-antimicrobial resistance in Pseudomonas aeruginosa strains causing chronic lung infections

scientific article published on August 2005

Identifying and exploiting genes that potentiate the evolution of antibiotic resistance

article

Impact of AmpC Derepression on Fitness and Virulence: the Mechanism or the Pathway?

scientific article published on 25 October 2016

Impact of multidrug resistance on the pathogenicity of Pseudomonas aeruginosa: in vitro and in vivo studies.

scientific article

In Vitro and In Vivo Activities of β-Lactams in Combination with the Novel β-Lactam Enhancers Zidebactam and WCK 5153 against Multidrug-Resistant Metallo-β-Lactamase-Producing Klebsiella pneumoniae

scientific article published on 25 April 2019

In Vivo Emergence of Resistance to Novel Cephalosporin-β-Lactamase Inhibitor Combinations through the Duplication of Amino Acid D149 from OXA-2 β-Lactamase (OXA-539) in Sequence Type 235 Pseudomonas aeruginosa.

scientific article published on 3 July 2017

In Vivo Selection of Moxifloxacin-Resistant Clostridium difficile ⬇️

scientific article published on February 27, 2012

In Vivo Validation of Peptidoglycan Recycling as a Target to Disable AmpC-Mediated Resistance and Reduce Virulence Enhancing the Cell-Wall-Targeting Immunity

scientific article published on 01 October 2019

In vitro activity of cefiderocol and other newly approved antimicrobials against multi-drug resistant Gram-negative pathogens recovered in intensive care units in Spain and Portugal

scholarly article

In vitro and in vivo efficacy of combinations of colistin and different endolysins against clinical strains of multi-drug resistant pathogens

scientific article published on 28 April 2020

In vitro dynamics and mechanisms of resistance development to imipenem and imipenem/relebactam in Pseudomonas aeruginosa

scientific article published on 08 June 2020

In vivo evolution of resistance of Pseudomonas aeruginosa strains isolated from patients admitted to an intensive care unit: mechanisms of resistance and antimicrobial exposure.

scientific article

Inactivation of the glycoside hydrolase NagZ attenuates antipseudomonal beta-lactam resistance in Pseudomonas aeruginosa

scientific article published on 9 March 2009

Inactivation of the mismatch repair system in Pseudomonas aeruginosa attenuates virulence but favors persistence of oropharyngeal colonization in cystic fibrosis mice.

scientific article published on 16 February 2007

Inappropriate use of antibiotics in hospitals: the complex relationship between antibiotic use and antimicrobial resistance

scientific article

Increased Antimicrobial Resistance in a Novel CMY-54 AmpC-Type Enzyme with a GluLeu(217-218) Insertion in the Ω-Loop.

scientific article published on 30 June 2017

Influence of virulence genotype and resistance profile in the mortality of Pseudomonas aeruginosa bloodstream infections

scientific article published on 6 November 2014

Inhibitor-resistant TEM- and OXA-1-producing Escherichia coli isolates resistant to amoxicillin-clavulanate are more clonal and possess lower virulence gene content than susceptible clinical isolates

scientific article

Insights into the evolution of the mutational resistome of Pseudomonas aeruginosa in cystic fibrosis

scientific article published on 25 October 2017

Interplay among Resistance Profiles, High-Risk Clones, and Virulence in the Caenorhabditis elegans Pseudomonas aeruginosa Infection Model.

scientific article published on 18 September 2017

Interplay between Peptidoglycan Biology and Virulence in Gram-Negative Pathogens

scientific article published on 12 September 2018

Intrinsic and environmental mutagenesis drive diversification and persistence of Pseudomonas aeruginosa in chronic lung infections

scientific article

Lack of association between hypermutation and antibiotic resistance development in Pseudomonas aeruginosa isolates from intensive care unit patients

scientific article

Mechanisms leading to in vivo ceftolozane/tazobactam resistance development during the treatment of infections caused by MDR Pseudomonas aeruginosa.

scientific article published on 14 November 2017

Metagenomics Analysis Reveals an Extraordinary Inner Bacterial Diversity in Anisakids (Nematoda: Anisakidae) L3 Larvae

scientific article published in 2021

Metallo-beta-lactamase-producing Pseudomonas putida as a reservoir of multidrug resistance elements that can be transferred to successful Pseudomonas aeruginosa clones

scientific article

Microbiological diagnostic procedures for respiratory cystic fibrosis samples in Spain: towards standard of care practices.

scientific article

Microbiological methods for surveillance of carrier status of multiresistant bacteria.

scientific article published on 8 February 2016

Molecular analysis of an outbreak of Serratia marcescens and its possible connection with the use of a chlorhexidine solution

scientific article published on 2 February 2016

Molecular and biochemical insights into the in vivo evolution of AmpC-mediated resistance to ceftolozane/tazobactam during treatment of an MDR Pseudomonas aeruginosa infection

scientific article published on 30 July 2020

Molecular characterization of a glycopeptide-resistant Enterococcus faecalis outbreak in an intensive care unit

scientific article published in October 2005

Molecular epidemiology and multidrug resistance mechanisms of Pseudomonas aeruginosa isolates from Bulgarian hospitals.

scientific article published on 21 April 2013

Molecular epidemiology and resistance profiles of Clostridium difficile in a tertiary care hospital in Spain ⬇️

scientific article published on March 22, 2013

Molecular identification of aminoglycoside-modifying enzymes in clinical isolates of Escherichia coli resistant to amoxicillin/clavulanic acid isolated in Spain.

scientific article

Molecular mechanisms driving the in vivo development of OXA-10-mediated resistance to ceftolozane/tazobactam and ceftazidime/avibactam during treatment of XDR Pseudomonas aeruginosa infections

scientific article published on 21 October 2020

Molecular mechanisms of beta-lactam resistance mediated by AmpC hyperproduction in Pseudomonas aeruginosa clinical strains.

scientific article published on November 2005

Multicenter Performance Evaluation of MALDI-TOF MS for Rapid Detection of Carbapenemase Activity in Enterobacterales: The Future of Networking Data Analysis With Online Software

scientific article published on 28 January 2022

Mutation and evolution of antibiotic resistance: antibiotics as promoters of antibiotic resistance?

scientific article

N-acetylcysteine selectively antagonizes the activity of imipenem in Pseudomonas aeruginosa by an OprD-mediated mechanism

scientific article published on 23 March 2015

Nontypable Haemophilus influenzae displays a prevalent surface structure molecular pattern in clinical isolates.

scientific article

Nosocomial outbreak linked to a flexible gastrointestinal endoscope contaminated with an amikacin-resistant ST17 clone of Pseudomonas aeruginosa

scientific article published on 06 May 2020

Nosocomial spread of colistin-only-sensitive sequence type 235 Pseudomonas aeruginosa isolates producing the extended-spectrum beta-lactamases GES-1 and GES-5 in Spain

scientific article published on 8 September 2009

Nosocomial spread of linezolid-resistant Staphylococcus hominis in two hospitals in Majorca ⬇️

scientific article published on March 23, 2011

Novel phosphorylcholine-containing protein of Pseudomonas aeruginosa chronic infection isolates interacts with airway epithelial cells

scientific article

O-antigen serotyping and MALDI-TOF, potentially useful tools for optimizing semi-empiric antipseudomonal treatments through the early detection of high-risk clones

scientific article published on 24 January 2019

OXA-24, a Novel Class D β-Lactamase with Carbapenemase Activity in an Acinetobacter baumannii Clinical Strain

scientific article published in June 2006

Optimization of a meropenem plus tobramycin combination dosage regimen against hypermutable and non-hypermutable Pseudomonas aeruginosa via mechanism-based modeling and the hollow-fiber infection model.

scientific article published on 5 February 2018

Overexpression of MexCD-OprJ reduces Pseudomonas aeruginosa virulence by increasing its susceptibility to complement-mediated killing.

scientific article published on 13 January 2014

PBP3 inhibition elicits adaptive responses in Pseudomonas aeruginosa.

scientific article published on 31 August 2006

Pan-β-Lactam Resistance Development in Pseudomonas aeruginosa Clinical Strains: Molecular Mechanisms, Penicillin-Binding Protein Profiles, and Binding Affinities ⬇️

scientific article published on June 25, 2012

Pathogenic characteristics of Pseudomonas aeruginosa bacteraemia isolates in a high-endemicity setting for ST175 and ST235 high-risk clones

scientific article published on 10 December 2019

Phenylboronic Acid Derivatives as Validated Leads Active in Clinical Strains Overexpressing KPC-2: A Step against Bacterial Resistance.

scientific article published on 22 January 2018

Potent β-Lactam Enhancer Activity of Zidebactam and WCK 5153 against Acinetobacter baumannii, Including Carbapenemase-Producing Clinical Isolates

scientific article published on 28 August 2017

Predicting antimicrobial resistance in Pseudomonas aeruginosa with machine learning-enabled molecular diagnostics

scientific article published on 12 February 2020

Prevalence of quinolone resistance mechanisms in Enterobacteriaceae producing acquired AmpC β-lactamases and/or carbapenemases in Spain.

scientific article published on 23 June 2016

Profiling the susceptibility of Pseudomonas aeruginosa strains from acute and chronic infections to cell-wall-targeting immune proteins

scientific article published on 05 March 2019

Programs for optimizing the use of antibiotics (PROA) in Spanish hospitals: GEIH-SEIMC, SEFH and SEMPSPH consensus document

scientific article published on 15 December 2011

Prospective multicenter study of carbapenemase-producing Enterobacteriaceae from 83 hospitals in Spain reveals high in vitro susceptibility to colistin and meropenem

scientific article published on 30 March 2015

Prospective multicenter study of the impact of carbapenem resistance on mortality in Pseudomonas aeruginosa bloodstream infections

scientific article published on 12 December 2011

Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway.

scientific article published on December 2011

Pseudomonas aeruginosa RsmA plays an important role during murine infection by influencing colonization, virulence, persistence, and pulmonary inflammation

scientific article

Pseudomonas aeruginosa carbapenem resistance mechanisms in Spain: impact on the activity of imipenem, meropenem and doripenem

article

Pseudomonas aeruginosa ceftolozane-tazobactam resistance development requires multiple mutations leading to overexpression and structural modification of AmpC

scientific article

Pseudomonas aeruginosa epidemic high-risk clones and their association with horizontally-acquired β-lactamases: 2020 update

scientific article published on 09 October 2020

Publisher Correction: Profiling the susceptibility of Pseudomonas aeruginosa strains from acute and chronic infections to cell-wall-targeting immune proteins

scientific article published on 04 March 2020

Rates of faecal colonization by carbapenemase-producing Enterobacteriaceae among patients admitted to ICUs in Spain: Table 1

article

Recomendaciones para la selección de antimicrobianos en el estudio de la sensibilidad in vitro con sistemas automáticos y semiautomáticos

scientific article published on 01 June 2007

Recommendations of the Spanish Antibiogram Committee (COESANT) for selecting antimicrobial agents and concentrations for in vitro susceptibility studies using automated systems

scientific article published on 14 March 2019

Regulation of AmpC-Driven β-Lactam Resistance in Pseudomonas aeruginosa: Different Pathways, Different Signaling

scientific article published on 03 December 2019

Risk factors for mortality among patients with Pseudomonas aeruginosa bacteraemia: a retrospective multicentre study

scientific article published on 23 November 2019

Role of Pseudomonas aeruginosa low-molecular-mass penicillin-binding proteins in AmpC expression, β-lactam resistance, and peptidoglycan structure.

scientific article published on 20 April 2015

Selective trihydroxyazepane NagZ inhibitors increase sensitivity of Pseudomonas aeruginosa to β-lactams

scientific article

Sequential Treatment of Biofilms with Aztreonam and Tobramycin Is a Novel Strategy for Combating Pseudomonas aeruginosa Chronic Respiratory Infections.

scientific article

Social Behavior of Antibiotic Resistant Mutants Within Biofilm Communities

scientific article published in 2019

Spanish consensus on the prevention and treatment of Pseudomonas aeruginosa bronchial infections in cystic fibrosis patients

scientific article

Spanish multicenter study of the epidemiology and mechanisms of amoxicillin-clavulanate resistance in Escherichia coli

scientific article

Spanish nationwide survey on Pseudomonas aeruginosa antimicrobial resistance mechanisms and epidemiology

scientific article published in 2019

Stepwise upregulation of the Pseudomonas aeruginosa chromosomal cephalosporinase conferring high-level beta-lactam resistance involves three AmpD homologues

scientific article

Structure and interaction with phospholipids of a prokaryotic lipoxygenase from Pseudomonas aeruginosa

scientific article

Surfactant Protein A Recognizes Outer Membrane Protein OprH on Pseudomonas aeruginosa Isolates From Individuals With Chronic Infection.

scientific article published on 19 August 2016

Susceptibility to R-pyocins of Pseudomonas aeruginosa clinical isolates from cystic fibrosis patients

scientific article published on 01 October 2018

Synergistic Meropenem-Tobramycin Combination Dosage Regimens against Clinical Hypermutable Pseudomonas aeruginosa at Simulated Epithelial Lining Fluid Concentrations in a Dynamic Biofilm Model

scientific article published on 22 October 2019

Synergistic activity of fosfomycin, β-lactams and peptidoglycan recycling inhibition against Pseudomonas aeruginosa

scientific article published on 20 December 2016

Targeting the permeability barrier and peptidoglycan recycling pathways to disarm Pseudomonas aeruginosa against the innate immune system.

scientific article

Temperate Bacteriophages (Prophages) in Pseudomonas aeruginosa Isolates Belonging to the International Cystic Fibrosis Clone (CC274)

scientific article published on 25 September 2020

The Pseudomonas aeruginosa CreBC two-component system plays a major role in the response to β-lactams, fitness, biofilm growth, and global regulation.

scientific article published on 16 June 2014

The Versatile Mutational Resistome of Pseudomonas aeruginosa.

scientific article published on 6 April 2018

The effect of elevated mutation rates on the evolution of cooperation and virulence of Pseudomonas aeruginosa

scientific article published on 17 August 2009

The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant

scientific article published on 30 September 2021

The increasing threat of Pseudomonas aeruginosa high-risk clones.

scientific article published on 10 August 2015

The mismatch repair system (mutS, mutL and uvrD genes) in Pseudomonas aeruginosa: molecular characterization of naturally occurring mutants

scientific journal article

The problems of antibiotic resistance in cystic fibrosis and solutions

scientific article published on 26 December 2014

The threat of the carbapenemase-producing enterobacteriaceae in Spain: positioning report of the SEIMC study groups, GEIH and GEMARA

scientific article published on 22 April 2014

Therapeutic Efficacy of LN-1-255 in Combination with Imipenem in Severe Infection Caused by Carbapenem-Resistant Acinetobacter baumannii

scientific article published on 23 September 2019

Transferable multidrug resistance plasmid carrying cfr associated with tet(L), ant(4')-Ia, and dfrK genes from a clinical methicillin-resistant Staphylococcus aureus ST125 strain

scientific article published on 3 January 2012

Understanding the acute inflammatory response to Pseudomonas aeruginosa infection: differences between susceptible and multidrug-resistant strains in a mouse peritonitis model

scientific article

Unusual Diversity of Acquired β-lactamases in Multidrug-ResistantPseudomonas aeruginosaIsolates in a Mexican Hospital ⬇️

scientific article published on 03 May 2012

Use of Calgary and Microfluidic BioFlux Systems To Test the Activity of Fosfomycin and Tobramycin Alone and in Combination against Cystic Fibrosis Pseudomonas aeruginosa Biofilms.

scientific article published on 30 October 2017

Use of Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry Analysis of Serum Peptidome to Classify and Predict Coronavirus Disease 2019 Severity

scientific article published on 02 May 2021

Using the Electronic Nose to Identify Airway Infection during COPD Exacerbations

scientific article published on 9 September 2015

VIM-2-producing multidrug-resistant Pseudomonas aeruginosa ST175 clone, Spain

scientific article

VIM-47, a New Variant of the Autochthonous Metallo-β-Lactamase VIM-13 from the Balearic Islands in Spain

scientific article published on 14 March 2016

Validation of MALDI-TOF for the early detection of the ST175 high-risk clone of Pseudomonas aeruginosa in clinical isolates belonging to a Spanish nationwide multicenter study

scientific article published on 15 July 2020

WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones

scientific article published on 13 March 2017

Whole-genome sequence-guided PCR for the rapid identification of thePseudomonas aeruginosa ST175 high-risk clone directly from clinical samples

scientific article published on 22 December 2020

[Carbapenemases in Pseudomonas spp]

scientific article published on 01 January 2010

[Microbiological diagnosis of bronchopulmonary colonization-infection in cystic fibrosis]

scientific article published on 20 February 2009

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