List of works - Dean J Naisbitt

7th Drug hypersensitivity meeting: part two.

scientific article

7th drug hypersensitivity meeting: part one.

scientific article

Application of in Vitro T Cell Assay Using Human Leukocyte Antigen-Typed Healthy Donors for the Assessment of Drug Immunogenicity.

scientific article published on 13 February 2018

Are chemically reactive metabolites responsible for adverse reactions to drugs?

scientific article

Are drug metabolites able to cause T-cell-mediated hypersensitivity reactions?

scientific article published on 15 December 2014

Cellular and molecular pathophysiology of cutaneous drug reactions

scientific article

Dapsone and Nitroso Dapsone Activation of Naı̈ve T-Cells from Healthy Donors.

scientific article

Dapsone- and nitroso dapsone-specific activation of T cells from hypersensitive patients expressing the risk allele HLA-B*13:01

scientific article published on 15 April 2019

Definition of Haptens Derived from Sulfamethoxazole: In Vitro and in Vivo

scientific article published on 11 September 2019

Drug hypersensitivity reactions in patients with HIV disease

scientific article published on May 2007

Drug-specific T-cell responses in patients with liver injury following treatment with the BACE inhibitor atabecestat

scientific article published on 04 November 2020

Gemcitabine and capecitabine with or without telomerase peptide vaccine GV1001 in patients with locally advanced or metastatic pancreatic cancer (TeloVac): an open-label, randomised, phase 3 trial

scientific article published on 19 June 2014

HLA-A*33:03-Restricted Activation of Ticlopidine-Specific T-Cells from Human Donors

scientific article published on 13 September 2018

IL-8 Release from Human Neutrophils Cultured with Pro-Haptenic Chemical Sensitizers ⬇️

scientific article published on September 12, 2012

Idiosyncratic Adverse Drug Reactions: Current Concepts ⬇️

scientific article published on March 8, 2013

Immune dysregulation increases the incidence of delayed-type drug hypersensitivity reactions

scientific article published on 23 November 2019

Immunological Mechanisms of Drug Hypersensitivity

scientific article

Immunological principles of T-cell-mediated adverse drug reactions in skin

scientific article

Immunological principles of adverse drug reactions: the initiation and propagation of immune responses elicited by drug treatment

scientific article

Implications of HLA-allele associations for the study of type IV drug hypersensitivity reactions

scientific article published on 20 February 2018

Mechanisms leading to T-cell activation in drug hypersensitivity

scientific article published on 01 August 2018

Metabolic activation in drug allergies.

scientific article

Modification of the cyclopropyl moiety of abacavir provides insight into the structure activity relationship between HLA-B*57:01 binding and T-cell activation

scientific article published on 09 October 2019

No Evidence for Drug-Specific Activation of Circulating T Cells from Patients with HLA-DRB1*07:01-Restricted Lapatinib-Induced Liver Injury

scientific article

Plasma cysteine deficiency and decreased reduction of nitrososulfamethoxazole with HIV infection

scientific article

Synthesis and reactions of nitroso sulphamethoxazole with biological nucleophiles: Implications for immune mediated toxicity

article

T cell responses to drugs and drug metabolites

scientific article published on January 2014

T-Cell Activation by Low Molecular Weight Drugs and Factors That Influence Susceptibility to Drug Hypersensitivity

scientific article published on 20 November 2019

The 2nd International Drug Hypersensitivity Meeting 18 - 21 April 2006, The University of Liverpool, Liverpool, UK.

scientific article published in September 2006

The Generation, Detection, and Effects of Reactive Drug Metabolites ⬇️

scientific article published on October 22, 2012

The chemical, genetic and immunological basis of idiosyncratic drug-induced liver injury.

scientific article

The danger hypothesis--potential role in idiosyncratic drug reactions

scientific article

The importance of hapten-protein complex formation in the development of drug allergy

scientific article

The skin as a metabolic and immune-competent organ: implications fordrug-induced skin rash

scientific article published on 14 October 2018

Tolvaptan- and Tolvaptan-Metabolite-Responsive T Cells in Patients with Drug-Induced Liver Injury

scientific article published on 21 October 2020

List of works by Dean J Naisbitt

7th Drug hypersensitivity meeting: part two.

7th drug hypersensitivity meeting: part one.

Application of in Vitro T Cell Assay Using Human Leukocyte Antigen-Typed Healthy Donors for the Assessment of Drug Immunogenicity.

Are chemically reactive metabolites responsible for adverse reactions to drugs?

Are drug metabolites able to cause T-cell-mediated hypersensitivity reactions?

Cellular and molecular pathophysiology of cutaneous drug reactions

Dapsone and Nitroso Dapsone Activation of Naı̈ve T-Cells from Healthy Donors.

Dapsone- and nitroso dapsone-specific activation of T cells from hypersensitive patients expressing the risk allele HLA-B*13:01

Definition of Haptens Derived from Sulfamethoxazole: In Vitro and in Vivo

Drug hypersensitivity reactions in patients with HIV disease

Drug-specific T-cell responses in patients with liver injury following treatment with the BACE inhibitor atabecestat

Gemcitabine and capecitabine with or without telomerase peptide vaccine GV1001 in patients with locally advanced or metastatic pancreatic cancer (TeloVac): an open-label, randomised, phase 3 trial

HLA-A*33:03-Restricted Activation of Ticlopidine-Specific T-Cells from Human Donors

IL-8 Release from Human Neutrophils Cultured with Pro-Haptenic Chemical Sensitizers ⬇️

Idiosyncratic Adverse Drug Reactions: Current Concepts ⬇️

Immune dysregulation increases the incidence of delayed-type drug hypersensitivity reactions

Immunological Mechanisms of Drug Hypersensitivity

Immunological principles of T-cell-mediated adverse drug reactions in skin

Immunological principles of adverse drug reactions: the initiation and propagation of immune responses elicited by drug treatment

Implications of HLA-allele associations for the study of type IV drug hypersensitivity reactions

Mechanisms leading to T-cell activation in drug hypersensitivity

Metabolic activation in drug allergies.

Modification of the cyclopropyl moiety of abacavir provides insight into the structure activity relationship between HLA-B*57:01 binding and T-cell activation

No Evidence for Drug-Specific Activation of Circulating T Cells from Patients with HLA-DRB1*07:01-Restricted Lapatinib-Induced Liver Injury

Plasma cysteine deficiency and decreased reduction of nitrososulfamethoxazole with HIV infection

Synthesis and reactions of nitroso sulphamethoxazole with biological nucleophiles: Implications for immune mediated toxicity

T cell responses to drugs and drug metabolites

T-Cell Activation by Low Molecular Weight Drugs and Factors That Influence Susceptibility to Drug Hypersensitivity

The 2nd International Drug Hypersensitivity Meeting 18 - 21 April 2006, The University of Liverpool, Liverpool, UK.

The Generation, Detection, and Effects of Reactive Drug Metabolites ⬇️

The chemical, genetic and immunological basis of idiosyncratic drug-induced liver injury.

The danger hypothesis--potential role in idiosyncratic drug reactions

The importance of hapten-protein complex formation in the development of drug allergy

The skin as a metabolic and immune-competent organ: implications fordrug-induced skin rash

Tolvaptan- and Tolvaptan-Metabolite-Responsive T Cells in Patients with Drug-Induced Liver Injury