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List of works by Marguerite R Irvin

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS study

scholarly article by Xueyan Zhao et al published 31 January 2019 in BMC Medical Genomics

A data-driven method for identifying rare variants with heterogeneous trait effects ⬇️

scientific article published on August 4, 2011

A family-specific linkage analysis of blood lipid response to fenofibrate in the Genetics of Lipid Lowering Drug and Diet Network

scientific article

A genome-wide association study of carotid atherosclerosis in HIV-infected men

scientific article

A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network

scientific article published on March 2012

A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies

scientific article published on 21 March 2016

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

scientific article

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study.

scientific article

APOL1 Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis

scientific article published on 05 August 2019

APOL1 nephropathy risk variants are associated with altered high-density lipoprotein profiles in African Americans

scientific article

Admixture Mapping of Subclinical Atherosclerosis and Subsequent Clinical Events Among African Americans in 2 Large Cohort Studies

scientific article published on April 2017

Admixture mapping of serum vitamin D and parathyroid hormone concentrations in the African American-Diabetes Heart Study

scientific article published on 23 March 2016

Advancing stroke genomic research in the age of Trans-Omics big data science: Emerging priorities and opportunities

scientific article published on 18 September 2017

An Exome-Wide Sequencing Study of the GOLDN Cohort Reveals Novel Associations of Coding Variants and Fasting Plasma Lipids

An epigenome-wide association study of inflammatory response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network

scientific article

An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort.

scientific article published on 20 February 2018

Apolipoprotein E polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the Genetics of Lipid Lowering and Diet Network (GOLDN) Study

scientific article

Apparent Treatment-resistant Hypertension Among Individuals with History of Stroke or Transient Ischemic Attack

scientific article published on 10 March 2015

Apparent treatment-resistant hypertension and risk for stroke, coronary heart disease, and all-cause mortality

scientific article

Archeological Echocardiography: Digitization and Speckle Tracking Analysis of Archival Echocardiograms in the HyperGEN Study

scientific article

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

scientific article

Association of Central Adiposity With Adverse Cardiac Mechanics: Findings From the Hypertension Genetic Epidemiology Network Study.

scientific article

Association of DNA Methylation at CPT1A Locus with Metabolic Syndrome in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Study

scientific article published on 25 January 2016

Association of Estimated Sodium Intake With Adverse Cardiac Structure and Function: From the HyperGEN Study

scientific article published on August 2017

Association of Sickle Cell Trait With Incidence of Coronary Heart Disease Among African American Individuals

scientific article published on 04 January 2021

Association of Sickle Cell Trait With Ischemic Stroke Among African Americans: A Meta-analysis.

scientific article published on 23 April 2018

Association of comorbidity burden with abnormal cardiac mechanics: findings from the HyperGEN study

scientific article

Association of low-grade albuminuria with adverse cardiac mechanics: findings from the hypertension genetic epidemiology network (HyperGEN) study.

scientific article published on 27 September 2013

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Changes in lipidomic profile by anti-retroviral treatment regimen: An ACTG 5257 ancillary study

scientific article published on 01 July 2021

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

scientific article

Chronic kidney disease and incident apparent treatment-resistant hypertension among blacks: Data from the Jackson Heart Study.

scientific article published on 17 September 2017

Clinical correlates and heritability of cardiac mechanics: The HyperGEN study

scientific article published on 11 July 2018

D-Dimer in African Americans: Whole Genome Sequence Analysis and Relationship to Cardiovascular Disease Risk in the Jackson Heart Study

scientific article published on 14 September 2017

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

scientific article published on 30 November 2017

Diastolic wall strain: a simple marker of abnormal cardiac mechanics

scientific article

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

scientific article

Distracted Driving and Risk of Crash or Near-Crash Involvement Among Older Drivers Using Naturalistic Driving Data With a Case-Crossover Study Design

scientific article published on 01 March 2019

Does the Association of Diabetes With Stroke Risk Differ by Age, Race, and Sex? Results From the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study

scientific article published on 07 August 2019

Driving with pets and motor vehicle collision involvement among older drivers: A prospective population-based study

scientific article published on 7 January 2016

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

scientific article published on 24 August 2020

Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies

scientific article published on January 2017

Epigenetic Signatures of Cigarette Smoking

scientific article

Epigenetics of Lipid Phenotypes.

scientific article

Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

scientific article published in May 2015

Epigenome-wide association study of fasting blood lipids in the Genetics of Lipid-lowering Drugs and Diet Network study

scientific article

Epigenome-wide association study of metabolic syndrome in African-American adults.

scientific article published on 10 April 2018

Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference

scientific article published on July 2015

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

Fine Mapping and Identification of BMI Loci in African Americans

scientific article published on October 2013

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

General cognitive impairment as a risk factor for motor vehicle collision involvement: a prospective population-based study.

scientific article published on 6 March 2018

Genetic and Adverse Health Outcome Associations with Treatment Resistant Hypertension in GenHAT.

scientific article published on 31 October 2013

Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium

scientific article

Genetic variants modify the effect of age on APOE methylation in the Genetics of Lipid Lowering Drugs and Diet Network study

scientific article

Genetics of Blood Pressure: New Insights Into a Complex Trait.

scientific article published on 7 April 2017

Genome- and CD4+ T-cell methylome-wide association study of circulating trimethylamine-N-oxide in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN).

scientific article published on 8 March 2017

Genome-wide admixture and association study of subclinical atherosclerosis in the Women's Interagency HIV Study (WIHS).

scientific article published on 4 December 2017

Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium.

scientific article

Genome-wide association of body fat distribution in African ancestry populations suggests new loci

scientific article

Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study

scientific article

Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry

scientific article published on 01 June 2018

Genomics of post-prandial lipidomic phenotypes in the Genetics of Lipid lowering Drugs and Diet Network (GOLDN) study

scientific article published on 6 June 2014

Healthy lifestyle factors and risk of cardiovascular events and mortality in treatment-resistant hypertension: the Reasons for Geographic and Racial Differences in Stroke study.

scientific article

Heritable DNA Methylation in CD4+ Cells among Complex Families Displays Genetic and Non-Genetic Effects

scientific article

Incident ESRD and treatment-resistant hypertension: the reasons for geographic and racial differences in stroke (REGARDS) study

scientific article

Influence of Kidney Transplant Status on Warfarin Dose, Anticoagulation Control, and Risk of Hemorrhage.

scientific article published on 26 September 2017

Influence of common and rare genetic variation on warfarin dose among African-Americans and European-Americans using the exome array

scientific article published on 7 July 2017

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

scientific article published on 14 October 2020

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

scientific article published on 10 April 2017

Local Ancestry and Clinical Cardiovascular Events Among African Americans From the Atherosclerosis Risk in Communities Study

scientific article published on 10 April 2017

Metabolic and inflammatory biomarkers are associated with epigenetic aging acceleration estimates in the GOLDN study.

scientific article

Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study

scientific article published in 2021

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

National patterns in intensity and frequency of outpatient care for apparent treatment-resistant hypertension.

scientific article published on 19 January 2017

Nephropathy Risk Variants and Incident Cardiovascular Disease Events in Community-Dwelling Black Adults

scientific article published on 01 June 2018

PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites

scientific article

PCSK9 Variants, LDL-Cholesterol, and Neurocognitive Impairment: The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study

scientific article published on 16 November 2017

PCSK9 variation and association with blood pressure in African Americans: preliminary findings from the HyperGEN and REGARDS studies

scientific article

Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study

scientific article

Pharmacogenetic effects of 'candidate gene complexes' on stroke in the GenHAT study

scientific article

Pharmacogenomics of high-density lipoprotein-cholesterol-raising therapies.

scientific article published on March 2013

Phenomapping for the Identification of Hypertensive Patients with the Myocardial Substrate for Heart Failure with Preserved Ejection Fraction

scientific article

Prevalence and correlates of low medication adherence in apparent treatment-resistant hypertension

scientific article

Prevalence of apparent treatment-resistant hypertension among individuals with CKD.

scientific article published on 18 July 2013

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 01 July 2019

RYR3 gene variants in subclinical atherosclerosis among HIV-infected women in the Women's Interagency HIV Study (WIHS).

scientific article published on 30 January 2014

Rare PPARA variants and extreme response to fenofibrate in the Genetics of Lipid-Lowering Drugs and Diet Network Study.

scientific article published in May 2012

Refractory hypertension: determination of prevalence, risk factors, and comorbidities in a large, population-based cohort

scientific article

Response to Letter Regarding Article, “Apolipoprotein E Polymorphisms and Postprandial Triglyceridemia Before and After Fenofibrate Treatment in the GOLDN Study”

Response to Should More Significance Be Granted to Medication Response to Antihypertensives in Patients With Resistant Hypertension?

scientific article published on 01 April 2014

SNPs located at CpG sites modulate genome-epigenome interaction

scientific article published on 28 June 2013

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

scientific article published on 6 March 2019

Serum magnesium concentration and incident cognitive impairment: the reasons for geographic and racial differences in stroke study

scientific article published on 31 July 2020

Sickle Cell Trait and the Risk of ESRD in Blacks

scientific article published on 9 March 2017

Sickle cell trait and risk of cognitive impairment in African-Americans: The REGARDS cohort

scientific article published on 24 May 2019

Stroke in Indigenous Africans, African Americans, and European Americans: Interplay of Racial and Geographic Factors

scientific article published on 7 April 2017

The association of nocturnal hypertension and nondipping blood pressure with treatment-resistant hypertension: The Jackson Heart Study.

scientific article published on 13 February 2018

The effects of angiotensinogen gene polymorphisms on cardiovascular disease outcomes during antihypertensive treatment in the GenHAT study

scientific article

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

scientific article

Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci

scientific article published on 8 April 2017

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article published on 23 December 2019

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article

Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate

scientific article

Visual Sensory and Visual-Cognitive Function and Rate of Crash and Near-Crash Involvement Among Older Drivers Using Naturalistic Driving Data.

scientific article

West African ancestry and nocturnal blood pressure in African Americans: the Jackson Heart Study

scientific article published on 8 March 2018

Whole exome analyses to examine the impact of rare variants on left ventricular traits in African American participants from the HyperGEN and GENOA studies

scientific article published on 20 July 2017

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