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List of works by Yoshimi Nakagawa

Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion

scientific article published on 02 June 2014

Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model

scientific article

Association between Lysosomal Dysfunction and Obesity-Related Pathology: A Key Knowledge to Prevent Metabolic Syndrome

scientific article published on 27 July 2019

CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.

scientific article published on 16 December 2016

CREBH Regulates Systemic Glucose and Lipid Metabolism.

scientific article published on 8 May 2018

Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes

scientific article published on 20 January 2020

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.

scientific article published on 30 September 2007

Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice

scientific article

Elovl6 Deficiency Improves Glycemic Control in Diabetic db/db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity.

scientific article

Elovl6 promotes nonalcoholic steatohepatitis

scientific article published on 01 December 2012

Elucidation of Molecular Mechanism of a Selective PPARα Modulator, Pemafibrate, through Combinational Approaches of X-ray Crystallography, Thermodynamic Analysis, and First-Principle Calculations

scientific article published on 06 January 2020

Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood.

scientific article published on 12 February 2018

Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice

scientific journal article

Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.

scientific article published on 18 September 2014

Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system

scientific article published on 13 June 2016

Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice

scientific article published on 12 September 2011

Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice

scientific article published in March 2004

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.

scientific article published on 17 September 2016

Macrophage Elovl6 Deficiency Ameliorates Foam Cell Formation and Reduces Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

scientific article published on 04 August 2011

Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets

scientific article published on 5 May 2008

Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver

scientific article published on 12 February 2007

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

scientific article

SREBPs suppress IRS-2-mediated insulin signalling in the liver

scientific article published on 14 March 2004

Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy

scientific article published on 14 September 2015

Srebp-1c/Fgf21/Pgc-1α Axis Regulated by Leptin Signaling in Adipocytes-Possible Mechanism of Caloric Restriction-Associated Metabolic Remodeling of White Adipose Tissue

scientific article published on 10 July 2020

Sterol Regulatory Element–Binding Protein-1 Determines Plasma Remnant Lipoproteins and Accelerates Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

scientific article published on 05 May 2011

TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis

scientific article published on 24 July 2013

TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin.

scientific article published on 2 December 2012

TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice

scientific article

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

scientific article published on 4 December 2005

The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice

scientific article published on 23 July 2018