List of works by Shyam Kottilil

1297. Characteristics for PrEP Uptake, Retention, and Discontinuation: Data From the ANCHOR Study

158 Hepatitis C Treatment Update: Current Status and Future Direcctions.

scientific article

Altered expression of SHIP, a Toll-like receptor pathway inhibitor, is associated with the severity of liver fibrosis in chronic hepatitis C virus infection

scientific article

Altered regulation of extrinsic apoptosis pathway in HCV-infected HCC cells enhances susceptibility to mapatumumab-induced apoptosis

scientific article published on 25 September 2009

Analysis of Notch and TGF-β Signaling Expression in Different Stages of Disease Progression During Hepatitis B Virus Infection

scientific article

Are we nearing the end in the fight against hepatitis C?

scientific article published on 24 March 2017

Assessment of outcomes of hepatitis C treatment--reply

scientific article published in December 2014

Association of interleukin-15-induced peripheral immune activation with hepatic stellate cell activation in persons coinfected with hepatitis C virus and HIV.

scientific article

Augmentation of hepatitis B virus-specific cellular immunity with programmed death receptor-1/programmed death receptor-L1 blockade in hepatitis B virus and HIV/hepatitis B virus coinfected patients treated with adefovir

scientific article published on 11 February 2013

B cells in early and chronic HIV infection: evidence for preservation of immune function associated with early initiation of antiretroviral therapy ⬇️

scientific article published on September 13, 2010

Beyond interferon: rationale and prospects for newer treatment paradigms for chronic hepatitis C.

scientific article

Can directly acting antiviral regimens against hepatitis C induce host immune responses?

article

Changes in hepatitis C viral response after initiation of highly active antiretroviral therapy and control of HIV viremia in chronically co-infected individuals

scientific article published in January 2004

Comparative efficacy, pharmacokinetic, pharmacodynamic activity, and interferon stimulated gene expression of different interferon formulations in HIV/HCV genotype-1 infected patients

scientific article

Comparison of the Abbott 7000 and Bayer 340 Systems for Measurement of Hepatitis C Virus Load

scientific article

Cytokine/chemokine patterns connect host and viral characteristics with clinics during chronic hepatitis C.

scientific article published on 11 May 2012

Decline in immature transitional B cells after hepatitis B vaccination in hepatitis B positive newborns.

scientific article published on July 2013

Differential Specificity of Interferon-alpha Inducible Gene Expression in Association with Human Immunodeficiency Virus and Hepatitis C Virus Levels and Declines in vivo

scientific article published on January 2015

Differential antiviral effect of PEG-interferon-alpha-2b on HIV and HCV in the treatment of HIV/HCV co-infected patients

scientific article published in September 2007

Drug-Drug Interactions in Patients Co-infected With HCV and HIV--Reply

scientific article published on July 2015

Dynamic Changes of Post-Translationally Modified Forms of CXCL10 and Soluble DPP4 in HCV Subjects Receiving Interferon-Free Therapy

scientific article published on 16 July 2015

Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: impaired viral kinetics and therapeutic response

scientific article

Effect of HIV co-infection on adherence to a 12-week regimen of hepatitis C virus therapy with ledipasvir and sofosbuvir

scientific article published on January 2016

Effect of sofosbuvir and ribavirin treatment on peripheral and hepatic lipid metabolism in chronic hepatitis C virus, genotype 1-infected patients

scientific article

Eradication Strategies for Chronic Hepatitis B Infection

scientific article published on June 2016

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

scientific article published on 14 July 2008

Expansion of Treatment for Hepatitis C Virus Infection

Expansion of Treatment for Hepatitis C Virus Infection by Task Shifting to Community-Based Nonspecialist Providers: A Nonrandomized Clinical Trial

scientific article published on 8 August 2017

Favorable adverse event profile of sofosbuvir/ribavirin compared to boceprevir/interferon/ribavirin for treatment of hepatitis C.

scientific article

Four-Week Direct-Acting Antiviral Regimens in Noncirrhotic Patients With Hepatitis C Virus Genotype 1 Infection: An Open-Label, Nonrandomized Trial.

scientific article

Functional genomics of innate host defense molecules in normal human monocytes in response to Aspergillus fumigatus

scientific article

Gene expression profiles predict emergence of psychiatric adverse events in HIV/HCV-coinfected patients on interferon-based HCV therapy

scientific article

HBV induces inhibitory FcRL receptor on B cells and dysregulates B cell-T follicular helper cell axis

scientific article published in Scientific Reports

HCC surveillance results in earlier HCC detection: results from an Indian cohort

scientific article

HCV in peripheral blood mononuclear cells are predominantly carried on the surface of cells in HIV/HCV co-infected individuals

scientific article published in December 2010

HIV Infection, hepatitis C infection, and HAART: hard clinical choices

scientific article published on July 2004

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

scientific article

HIV/HCV-coinfected natural viral suppressors have better virologic responses to PEG-IFN and ribavirin than ARV-treated HIV/HCV patients

scientific article

HIV/Hepatitis C Virus-Coinfected Virologic Responders to Pegylated Interferon and Ribavirin Therapy More Frequently Incur Interferon-Related Adverse Events Than Nonresponders Do

scientific article

Hepatic histologic response (HR) to combination therapy among HCV/HIV-coinfected individuals: interferon induces HR independent of sustained virologic response (SVR).

scientific article published in November 2006

Hepatitis B & hepatitis C in HIV-infection.

scientific article

Hepatitis C Viral Kinetics During Treatment With Peg IFN-alpha-2b in HIV/HCV Coinfected Patients as a Function of Baseline CD4+ T-Cell Counts

scientific article

Hepatitis C genotype 3 disease.

scientific article

Hepatitis C-associated mixed cryoglobulinemic vasculitis induces differential gene expression in peripheral mononuclear cells

scientific article

High adherence to all-oral directly acting antiviral HCV therapy among an inner-city patient population in a phase 2a study

scientific article published on 26 November 2015

High interferon-stimulated gene ISG-15 expression affects HCV treatment outcome in patients co-infected with HIV and HCV.

scientific article published on June 2013

Host gene expression changes correlating with anti-HIV-1 effects in human subjects after treatment with peginterferon Alfa-2a

scientific article published on 26 March 2012

Human immunodeficiency virus and hepatitis C infections induce distinct immunologic imprints in peripheral mononuclear cells

scientific article published on July 2009

Human immunodeficiency virus viremia induces plasmacytoid dendritic cell activation in vivo and diminished alpha interferon production in vitro.

scientific article published on 6 February 2008

IFNL4 Genotype Is Associated With Virologic Relapse After 8-Week Treatment With Sofosbuvir, Velpatasvir, and Voxilaprevir

scientific article published on 3 November 2017

IL28B polymorphism is not associated with HCV protease diversity in patients co-infected with HIV and HCV treated with pegylated interferon and ribavirin

scientific article published on October 2012

ITPA gene polymorphisms significantly affect hemoglobin decline and treatment outcomes in patients coinfected with HIV and HCV.

scientific article

Identification of novel markers for liver fibrosis in HIV/hepatitis C virus coinfected individuals using genomics-based approach

scientific article published on July 2008

Idiopathic CD4+ T lymphocytopenia is associated with increases in immature/transitional B cells and serum levels of IL-7

scientific article

Immune biomarker differences and changes comparing HCV mono-infected, HIV/HCV co-infected, and HCV spontaneously cleared patients

scientific article

Immunodeficiency and intrinsic IFN resistance are associated with viral breakthrough to HCV therapy in HIV-coinfected patients

scientific article published in November 2007

Impact of HIV on cell survival and antiviral activity of plasmacytoid dendritic cells

scientific article

Impact of interferon-ribavirin treatment on hepatitis C virus (HCV) protease quasispecies diversity in HIV- and HCV-coinfected patients

scientific article

Impaired HCV clearance in HIV/HCV coinfected subjects treated with PegIFN and RBV due to interference of IFN signaling by IFNαR2a

scientific article published on 30 October 2013

Impaired monocyte-macrophage functions and defective Toll-like receptor signaling in hepatitis E virus-infected pregnant women with acute liver failure

scientific article published on 31 August 2015

Infections caused by Scedosporium spp.

scientific article

Innate Immunity in HIV Infection

article

Innate immune dysfunction in HIV infection: effect of HIV envelope-NK cell interactions

article

Innate immunity in human immunodeficiency virus infection: effect of viremia on natural killer cell function

scientific article published on 13 March 2003

Inteleukin-23 promotes interferon-α responsiveness in hepatitis C virus/HIV-coinfected patients ⬇️

scientific article

Interferon Stimulated Gene Expression in HIV/HCV Coinfected Patients Treated with Nitazoxanide/Peginterferon-Alfa-2a and Ribavirin

scientific article published on 14 March 2016

Interferon stimulated exonuclease gene 20 kDa links psychiatric events to distinct hepatitis C virus responses in human immunodeficiency virus positive patients

scientific article

Interferon-Free Treatment of Hepatitis C Virus in HIV/Hepatitis C Virus-Coinfected Subjects Results in Increased Serum Low-Density Lipoprotein Concentration

scientific article published on 11 November 2015

Intracerebral tuberculoma misdiagnosed as neurosarcoidosis

scientific article published in May 2003

LIPS arrays for simultaneous detection of antibodies against partial and whole proteomes of HCV, HIV and EBV.

scientific article

Ledipasvir and sofosbuvir for hepatitis C genotype 4: a proof-of-concept, single-centre, open-label phase 2a cohort study

scientific article

Longterm Evaluation of Hemoglobin A1c Following Hepatitis C Therapy in Patients with and without HIV Co-infection.

scientific article published on 4 October 2017

Mechanisms of alcohol-induced hepatocellular carcinoma

scientific article

MicroRNA expression profiling in HCV-infected human hepatoma cells identifies potential anti-viral targets induced by interferon-α

scientific article

Multitarget Direct-Acting Antiviral Therapy Is Associated With Superior Immunologic Recovery in Patients Coinfected With Human Immunodeficiency Virus and Hepatitis C Virus.

scientific article published on 27 September 2018

NK cells in HIV infection: paradigm for protection or targets for ambush

scientific article

Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates

scientific article

Natural killer cells in HIV-1 infection: role of NK cell-mediated non-cytolytic mechanisms in pathogenesis of HIV-1 infection.

scientific article published in November 2003

No Improvement in Hemoglobin A1c Following Hepatitis C Viral Clearance in Patients With and Without HIV.

scientific article published on 17 November 2017

No scientific basis to restrict 8 weeks of treatment with ledipasvir/sofosbuvir to patients with hepatitis C virus RNA <6,000,000 IU/mL

scientific article

Normalization of B cell counts and subpopulations after antiretroviral therapy in chronic HIV disease.

scientific article published in February 2008

On-Treatment Elevation in Hepatic Transaminases during HCV Treatment with Ombitasvir, Paritaprevir, Dasabuvir, Ritonavir, and Ribavirin: A Case Series.

scientific article published on 26 May 2016

Patient-reported outcomes in patients co-infected with hepatitis C virus and human immunodeficiency virus treated with sofosbuvir and velpatasvir: The ASTRAL-5 study

scientific article published on 4 May 2017

Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy

scientific article

Persistently elevated abnormal B-cell subpopulations and anti-core antibodies in patients co-infected with HIV/HCV who relapse

scientific article published on 21 January 2015

Predictors for hematopoietic growth factors use in HIV/HCV-coinfected patients treated with peginterferon alfa 2b and ribavirin

scientific article published in September 2006

Proteome-wide anti-hepatitis C virus (HCV) and anti-HIV antibody profiling for predicting and monitoring the response to HCV therapy in HIV-coinfected patients

scientific article

Race or genetic makeup for hepatitis C virus treatment decisions?

scientific article published on 18 January 2017

Rapid changes in peripheral lymphocyte concentrations during interferon-free treatment of chronic hepatitis C virus infection.

scientific article published on 24 July 2017

Rapid development of advanced liver fibrosis after acquisition of hepatitis C infection during primary HIV infection.

scientific article

Re-treatment of chronic hepatitis C virus genotype 1 infection after relapse: an open-label pilot study

scientific article

Relationship between the frequency of HIV-specific CD8+ T cells and the level of CD38+CD8+ T cells in untreated HIV-infected individuals

scholarly article

Reply to Harrington et al.

scientific article

Safe and effective sofosbuvir-based therapy in patients with mental health disease on hepatitis C virus treatment

scientific article

Safety, tolerability, and mechanisms of antiretroviral activity of pegylated interferon Alfa-2a in HIV-1-monoinfected participants: a phase II clinical trial

scientific article

Serious ophthalmic pathology compromising vision in HCV/HIV co-infected patients treated with peginterferon alpha-2b and ribavirin

scientific article

Short communication: Interferon/ribavirin treatment for HCV is associated with the development of hypophosphatemia in HIV/hepatitis C virus-coinfected patients

scientific article published on 14 June 2013

Short communication: serum-based assay accurately detects single nucleotide polymorphisms of IL28B and SOCS3 in HIV/hepatitis C virus-coinfected subjects

scientific article

Shortening Treatment for Hepatitis C Virus Infection.

scientific article published in March 2018

Shortening the duration of therapy for chronic hepatitis C infection

scientific article published on 09 August 2017

Simtuzumab treatment of advanced liver fibrosis in HIV and HCV-infected adults: results of a 6-month open-label safety trial

scientific article

Sofosbuvir and Velpatasvir for the Treatment of HCV in Patients Coinfected with HIV-1: an Open-Label, Phase 3 Study

scientific article published on 29 March 2017

Sofosbuvir and ledipasvir for HIV/HCV co-infected patients

scientific article published on 21 February 2016

Sofosbuvir and velpatasvir: a stellar option for patients with decompensated hepatitis C virus (HCV) cirrhosis

scientific article published on October 2016

Sofosbuvir for treatment of chronic hepatitis C.

scientific article published on 28 January 2015

Sofosbuvir/velpatasvir: a pangenotypic drug to simplify HCV therapy

scientific article published on 7 December 2016

Steatosis is an independent predictor of relapse following rapid virologic response in patients with HCV genotype 3.

scientific article

Strategies to eliminate HBV infection

scientific article

Successful Retreatment of Chronic HCV Genotype-1 Infection With Ledipasvir and Sofosbuvir After Initial Short Course Therapy With Direct-Acting Antiviral Regimens.

scientific article

Sustained Virologic Response for Chronic Hepatitis C Infection after 27 Days of Treatment with Sofosbuvir and Ribavirin.

scientific article

Targeted lysis of HIV-infected cells by natural killer cells armed and triggered by a recombinant immunoglobulin fusion protein: implications for immunotherapy.

scientific article published on February 2005

The interferon stimulated gene 15 functions as a proviral factor for the hepatitis C virus and as a regulator of the IFN response.

scientific article

The paradox of highly effective sofosbuvir-based combination therapy despite slow viral decline: can we still rely on viral kinetics?

scientific article published on 31 August 2017

Therapeutic response to peg-IFN-alpha-2b and ribavirin in HIV/HCV co-infected African-American and Caucasian patients as a function of HCV viral kinetics and interferon pharmacodynamics

scientific article

Tickling the TLR7 to cure viral hepatitis

scientific article

Time to end treatment restrictions for people with hepatitis C who inject drugs

scientific article published on 5 January 2018

Treatment of Chronic Hepatitis B Infection-Reply

scientific article published in The Journal of the American Medical Association

Treatment of hepatitis B virus: an update

scientific article published on 18 November 2016

Treatment of hepatitis C in patients with HIV.

scientific article published on 9 July 2015

Treatment of hepatitis C virus infection: is it time for the internist to take the reins?

scientific article published on September 2014

Treatment of hepatitis C with 8 weeks of ledipasvir/sofosbuvir: highly effective in a predominantly black male patient population

scientific article published on 6 October 2017

Treatment of hepatitis C: a systematic review

scientific article

Twice-weekly pegylated interferon-α-2a and ribavirin results in superior viral kinetics in HIV/hepatitis C virus co-infected patients compared to standard therapy

scientific article

Utility of hepatitis C viral load monitoring on direct-acting antiviral therapy

scientific article published on 2 March 2015

Variant Inosine Triphosphatase Phenotypes Are Associated With Increased Ribavirin Triphosphate Levels

scientific article published on 28 June 2016

Virologic response following combined ledipasvir and sofosbuvir administration in patients with HCV genotype 1 and HIV co-infection

scientific article published on March 2015

Virological response after 6 week triple-drug regimens for hepatitis C: a proof-of-concept phase 2A cohort study

scientific article published on 13 January 2015

What does the pharmacological future of treating chronic hepatitis C look like?

scientific article published on 06 August 2015

miRNA signatures can predict acute liver failure in hepatitis E infected pregnant females

scientific article published on 06 April 2017

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