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List of works by Jonathan A McCullers

A Single Point Mutation (Y89F) within the Non-Structural Protein 1 of Influenza A Viruses Limits Epithelial Cell Tropism and Virulence in Mice

article by Eike R. Hrincius et al published June 2012 in The American Journal of Pathology

A live-attenuated pneumococcal vaccine elicits CD4+ T-cell dependent class switching and provides serotype independent protection against acute otitis media

scientific article published on January 2014

A multi-valent vaccine approach that elicits broad immunity within an influenza subtype.

scientific article published on 07 January 2009

A novel cytotoxic sequence contributes to influenza A viral protein PB1-F2 pathogenicity and predisposition to secondary bacterial infection

scientific article published on 30 October 2013

A practical guide to alcohol-based hand hygiene infrastructure in a resource-poor pediatric hospital.

scientific article published on December 2009

A single amino acid change in the C-terminal domain of the matrix protein M1 of influenza B virus confers mouse adaptation and virulence

scientific article published on June 2005

A step closer to meeting the threat of avian influenza

scientific article published in September 2006

Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway

scientific article

Adjunctive corticosteroid therapy improves lung immunopathology and survival during severe secondary pneumococcal pneumonia in mice

scientific article published on 23 November 2013

Advances in vaccine technology and their impact on managed care.

scientific article published on January 2008

Antibiotic Choice for Children Hospitalized With Pneumonia and Adherence to National Guidelines

scientific article published on July 2015

Antimicrobial peptides alter early immune response to influenza A virus infection in C57BL/6 mice

scientific article

Antiviral therapy of influenza.

scientific article

Are toilet seats a vector for transmission of methicillin-resistant Staphylococcus aureus?

scientific article

Association Between Hospitalization With Community-Acquired Laboratory-Confirmed Influenza Pneumonia and Prior Receipt of Influenza Vaccination

scientific article

Association of sputum microbiota profiles with severity of community-acquired pneumonia in children

scientific article

Bacterial sinusitis and otitis media following influenza virus infection in ferrets

scientific article published on May 2006

Chloroquine is effective against influenza A virus in vitro but not in vivo

scientific article published on September 2007

Chronic helminth infections impair pneumococcal vaccine responses

scientific article published on 13 August 2014

Community-Acquired Pneumonia Hospitalization among Children with Neurologic Disorders

scientific article published on 17 March 2016

Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults

scientific article published on 14 July 2015

Community-acquired pneumonia requiring hospitalization among U.S. children

scientific article

Comparison of immune response to the influenza vaccine in obese and nonobese healthcare workers

scientific article published on March 2015

Contribution of vaccine-induced immunity toward either the HA or the NA component of influenza viruses limits secondary bacterial complications

scientific article

Correlates of vaccine protection from influenza and its complications ⬇️

scientific article published on January 1, 2012

Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections ⬇️

scientific article published on June 26, 2013

Distinct contributions of vaccine-induced immunoglobulin G1 (IgG1) and IgG2a antibodies to protective immunity against influenza

scientific article

Does Glycosylation as a modifier of Original Antigenic Sin explain the case age distribution and unusual toxicity in pandemic novel H1N1 influenza?

scientific article

Early vancomycin therapy and adverse outcomes in children with pneumococcal meningitis

scientific article published in May 2006

Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics

scientific article

Effect of antiviral treatment on the outcome of secondary bacterial pneumonia after influenza

scientific article published on 30 June 2004

Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus

scientific article

Evolution, benefits, and shortcomings of vaccine management.

scientific article published on September 2007

Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia

scientific article

Fatal influenza B infections: time to reexamine influenza research priorities

scientific article

Fatal outcome of pandemic H1N1 2009 influenza virus infection is associated with immunopathology and impaired lung repair, not enhanced viral burden, in pregnant mice

scientific article

FluBlok, a recombinant influenza vaccine

scientific article published on 01 February 2008

Glycan Shielding of the Influenza Virus Hemagglutinin Contributes to Immunopathology in Mice ⬇️

scientific article published on October 8, 2010

Glycosylation Analysis of Engineered H3N2 Influenza A Virus Hemagglutinins with Sequentially Added Historically Relevant Glycosylation Sites.

scientific article

Glycosylation changes in the globular head of H3N2 influenza hemagglutinin modulate receptor binding without affecting virus virulence

scientific article

Healthcare-Associated Infections at a Children's Cancer Hospital, 1983–2008 ⬇️

scientific article published on March 1, 2012

Helminth infections predispose mice to pneumococcal pneumonia but not to other pneumonic pathogens

scientific article published on 21 June 2014

Identification of Bacterial and Viral Codetections With Mycoplasma pneumoniae Using the TaqMan Array Card in Patients Hospitalized With Community-Acquired Pneumonia

scientific article published on 30 March 2016

Immunogenicity and safety of high-dose trivalent inactivated influenza vaccine compared to standard-dose vaccine in children and young adults with cancer or HIV infection

scientific article published on 26 April 2016

Immunogenicity and safety of inactivated monovalent 2009 H1N1 influenza A vaccine in immunocompromised children and young adults ⬇️

scientific article published on December 9, 2011

Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82 ⬇️

scientific article published on September 21, 2011

Immunotherapy with a Combination of Intravenous Immune Globulin and P4 Peptide Rescues Mice from Postinfluenza Pneumococcal Pneumonia ⬇️

scientific article published on March 7, 2011

Impaired wound healing predisposes obese mice to severe influenza virus infection

scientific article

Improving therapeutic strategies for secondary bacterial pneumonia following influenza

scientific article

Increased influenza vaccination of healthcare workers at a pediatric cancer hospital: results of a comprehensive influenza vaccination campaign

scientific article published on 06 January 2006

Influence of Antibiotics on the Detection of Bacteria by Culture-Based and Culture-Independent Diagnostic Tests in Patients Hospitalized With Community-Acquired Pneumonia

scientific article

Influenza enhances susceptibility to natural acquisition of and disease due to Streptococcus pneumoniae in ferrets.

scientific article

Influenza virus neuraminidase contributes to secondary bacterial pneumonia

scientific article published on 08 June 2005

Influenza virus primes mice for pneumonia from Staphylococcus aureus.

scientific article

Influenza: annual seasonal severity

scientific article published on 01 February 2019

Insights into the interaction between influenza virus and pneumococcus

scientific article

Kinetics of coinfection with influenza A virus and Streptococcus pneumoniae

scientific article

Lethal synergism between influenza virus and Streptococcus pneumoniae: characterization of a mouse model and the role of platelet-activating factor receptor

scientific article

Levels of total fungus and Aspergillus on a pediatric hematopoietic stem cell transplant unit

scientific article published on March 2004

Live attenuated influenza vaccine enhances colonization of Streptococcus pneumoniae and Staphylococcus aureus in mice

scientific article published on 18 February 2014

Live attenuated influenza vaccine is safe and immunogenic in immunocompromised ferrets

scientific article published on 27 January 2006

Live attenuated influenza virus increases pneumococcal translocation and persistence within the middle ear.

scientific article published on 11 December 2014

Live, attenuated influenza virus (LAIV) vehicles are strong inducers of immunity toward influenza B virus

scientific article published on 15 August 2008

Low Retinol-Binding Protein and Vitamin D Levels Are Associated with Severe Outcomes in Children Hospitalized with Lower Respiratory Tract Infection and Respiratory Syncytial Virus or Human Metapneumovirus Detection

scientific article published on 31 May 2017

Mathematical model of a three-stage innate immune response to a pneumococcal lung infection ⬇️

scientific article published on February 12, 2011

Molecular Detection and Characterization of Mycoplasma pneumoniae Among Patients Hospitalized With Community-Acquired Pneumonia in the United States

scientific article

Molecular signatures of virulence in the PB1-F2 proteins of H5N1 influenza viruses.

scientific article

Motivating factors for high rates of influenza vaccination among healthcare workers ⬇️

scientific article published on June 23, 2011

Multiple genotypes of influenza B virus circulated between 1979 and 2003.

scientific article published on December 2004

Mycoplasma pneumoniae Among Children Hospitalized With Community-acquired Pneumonia ⬇️

scientific article published on 01 January 2019

N-linked glycosylation attenuates H3N2 influenza viruses

scientific article

Naturally Occurring Swine Influenza A Virus PB1-F2 Phenotypes That Contribute to Superinfection with Gram-Positive Respiratory Pathogens ⬇️

scientific article published on June 6, 2012

New virulence determinants contribute to the enhanced immune response and reduced virulence of an influenza A virus A/PR8/34 variant

scientific article published on 27 August 2013

No evidence of a link between influenza vaccines and Guillain–Barre syndrome–associated antiganglioside antibodies ⬇️

scientific article published on September 29, 2011

Non-avian animal reservoirs present a source of influenza A PB1-F2 proteins with novel virulence-enhancing markers

scientific article

Nonstructural protein 1 (NS1)-mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections: insights into 1918 H1N1 pandemic?

scientific article

Novel strategy to prevent otitis media caused by colonizing Streptococcus pneumoniae

scientific article

Oseltamivir Use Among Children and Adults Hospitalized With Community-Acquired Pneumonia

scientific article

PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology

scientific article

Planning and implementation of an infection control training program for healthcare providers in Latin America

scientific article published on 22 October 2007

Planning for an influenza pandemic: thinking beyond the virus.

scientific article

Predicting Severe Pneumonia Outcomes in Children

scientific article

Preparing for the next influenza pandemic.

scientific article

Preventing and treating secondary bacterial infections with antiviral agents

scientific article

Randomized, double-blind comparison of standard-dose vs. high-dose trivalent inactivated influenza vaccine in pediatric solid organ transplant patients

scientific article published on 18 December 2014

Receptor-binding specificity of the human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoprotein ⬇️

scientific article published on August 16, 2011

Recipients of vaccine against the 1976 "swine flu" have enhanced neutralization responses to the 2009 novel H1N1 influenza virus

scientific article

Relationship Between Body Mass Index and Outcomes Among Hospitalized Patients With Community-Acquired Pneumonia

article published in 2017

Respiratory viruses predisposing to bacterial infections: role of neuraminidase

scientific article published on January 2004

Rhinovirus Viremia in Patients Hospitalized With Community-Acquired Pneumonia

scientific article

Risk of catheter-associated infection in young hematology/oncology patients receiving long-term peripheral nerve blocks

scientific article

Role of neuraminidase in lethal synergism between influenza virus and Streptococcus pneumoniae

scientific article published on 6 March 2003

Safety and immunogenicity of live attenuated and inactivated influenza vaccines in children with cancer

scientific article published on 23 September 2011

Safety of high dose trivalent inactivated influenza vaccine in pediatric patients with acute lymphoblastic leukemia

scientific article

Safety of live attenuated influenza vaccine in mild to moderately immunocompromised children with cancer ⬇️

scientific article published on April 13, 2011

Secondary bacterial infections in influenza virus infection pathogenesis.

scientific article published on January 2014

Secondhand Smoke Exposure and Illness Severity among Children Hospitalized with Pneumonia

scientific article

Serology Enhances Molecular Diagnosis of Respiratory Virus Infections Other than Influenza in Children and Adults Hospitalized with Community-Acquired Pneumonia

scientific article published on 19 October 2016

Seroprevalence of seasonal and pandemic influenza A viruses in domestic cats ⬇️

scientific article published on September 28, 2010

T cell receptor αβ diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection

scientific article published on April 2012

The Role of Punctuated Evolution in the Pathogenicity of Influenza Viruses

scientific article

The age distribution of mortality due to influenza: pandemic and peri-pandemic ⬇️

scientific article published on December 12, 2012

The clinical need for new antiviral drugs directed against influenza virus

scientific article

The co-pathogenesis of influenza viruses with bacteria in the lung.

scientific article

The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact pathogenesis

scientific article

The immune profile associated with acute allergic asthma accelerates clearance of influenza virus

scientific article

The novel parainfluenza virus hemagglutinin-neuraminidase inhibitor BCX 2798 prevents lethal synergism between a paramyxovirus and Streptococcus pneumoniae

scientific article

The platelet activating factor receptor is not required for exacerbation of bacterial pneumonia following influenza

scientific article published on 21 June 2007

The public health policy implications of understanding metabiosis

scientific article published on July 2014

Therapeutics Against Influenza ⬇️

scientific article published on January 1, 2013

Toll-Like Receptor 2 Mediates Fatal Immunopathology in Mice During Treatment of Secondary Pneumococcal Pneumonia Following Influenza ⬇️

scientific article published on September 7, 2011

Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenza

scientific article published on February 2009

Use of Multiple Imputation to Estimate the Proportion of Respiratory Virus Detections Among Patients Hospitalized With Community-Acquired Pneumonia.

scientific article published on 16 March 2018

Use of atmospheric non-thermal plasma as a disinfectant for objects contaminated with methicillin-resistant Staphylococcus aureus

scientific article published on 25 June 2009

Vaccines against pandemic influenza: what can be done before the next pandemic?

scientific article

Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions

scientific article

Virulent PB1-F2 residues: effects on fitness of H1N1 influenza A virus in mice and changes during evolution of human influenza A viruses.

scientific article

WASP- mice exhibit defective immune responses to influenza A virus, Streptococcus pneumoniae, and Mycobacterium bovis BCG.

scientific article published in April 2005

Wild-type and attenuated influenza virus infection of the neonatal rat brain

scientific article published in October 2004

c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection.

scientific article published on 18 July 2008

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