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List of works by Sophie Vacher

A Molecular Predictor Reassesses Classification of Human Grade II/III Gliomas

scientific article

Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer

scientific article published on 22 December 2015

Arpin downregulation in breast cancer is associated with poor prognosis

scientific article

CAG repeat size in Huntingtin alleles is associated with cancer prognosis

scientific article

CXC chemokines located in the 4q21 region are up-regulated in breast cancer.

scientific article published in December 2007

Cdk5 promotes DNA replication stress checkpoint activation through RPA-32 phosphorylation, and impacts on metastasis free survival in breast cancer patients

scientific article published on 3 August 2015

Cell death and neuronal differentiation of glioblastoma stem-like cells induced by neurogenic transcription factors.

scientific article published on 9 October 2012

Control of MT1-MMP transport by atypical PKC during breast-cancer progression

scientific article

Correlation between messenger RNA expression and protein expression of immune checkpoint-associated molecules in bladder urothelial carcinoma: A retrospective study

scientific article published on 10 March 2017

DNA repair gene expression and risk of locoregional relapse in breast cancer patients.

scientific article published on 21 January 2010

Differential distribution of erbB receptors in human glioblastoma multiforme: expression of erbB3 in CD133-positive putative cancer stem cells

scientific article

Distinct expression profiles and functions of Kindlins in breast cancer

ERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomas

scientific article published on 02 September 2016

ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

article published in 2018

Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data

scientific article published on 24 February 2015

Exome sequencing reveals aberrant signalling pathways as hallmark of treatment-naive anal squamous cell carcinoma

scientific article published on 8 December 2017

Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy

scientific article

Gain-of-function Prolactin Receptor Variants Are Not Associated With Breast Cancer and Multiple Fibroadenoma Risk

scientific article published on 30 August 2016

Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway

scientific article

Genome-wide DNA methylation profiling of CpG islands in breast cancer identifies novel genes associated with tumorigenicity.

scientific article published on March 2011

High AHR expression in breast tumors correlates with expression of genes from several signaling pathways namely inflammation and endogenous tryptophan metabolism

scientific article published on 10 January 2018

High tumoral levels of Kiss1 and G-protein-coupled receptor 54 expression are correlated with poor prognosis of estrogen receptor-positive breast tumors.

scientific article published in September 2007

Identification of 5 novel genes methylated in breast and other epithelial cancers

scientific article

Identification of new candidate therapeutic target genes in head and neck squamous cell carcinomas

scientific article published on 18 June 2016

Identification of new candidate therapeutic target genes in triple-negative breast cancer

scientific article

Importance of pre-analytical steps for transcriptome and RT-qPCR analyses in the context of the phase II randomised multicentre trial REMAGUS02 of neoadjuvant chemotherapy in breast cancer patients

scientific article

Inhibitory signalling to the Arp2/3 complex steers cell migration

scientific article

Large-scale real-time reverse transcription-PCR approach of angiogenic pathways in human transitional cell carcinoma of the bladder: identification of VEGFA as a major independent prognostic marker.

scientific article published on 23 May 2008

MDA-MB-231 breast cancer cells overexpressing single VEGF isoforms display distinct colonisation characteristics.

scientific article

MED12 mutations in breast phyllodes tumors: evidence of temporal tumoral heterogeneity and identification of associated critical signaling pathways

scientific article published on 31 October 2016

MiR-190b, the highest up-regulated miRNA in ERα-positive compared to ERα-negative breast tumors, a new biomarker in breast cancers?

scientific article published on 5 July 2015

NF-kappa B genes have a major role in inflammatory breast cancer

scientific article

PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups

scientific article

PIK3R1 underexpression is an independent prognostic marker in breast cancer

scientific article

Predictive gene signature of response to the anti-TweakR mAb PDL192 in patient-derived breast cancer xenografts

scientific article

Profiling of EGFR mRNA and protein expression in 471 breast cancers compared with 10 normal tissues: a candidate biomarker to predict EGFR inhibitor effectiveness.

scientific article published on 30 November 2011

Prognostic value of a newly identified MALAT1 alternatively spliced transcript in breast cancer

scientific article published on 12 May 2016

Protein kinase D1 regulates ERα-positive breast cancer cell growth response to 17β-estradiol and contributes to poor prognosis in patients

scientific article

Quantification of PKC family genes in sporadic breast cancer by qRT‐PCR: Evidence that PKCι/λ overexpression is an independent prognostic factor ⬇️

scientific article published on May 21, 2012

Rare overexpression of anaplastic lymphoma kinase gene in inflammatory and non-inflammatory breast cancer.

scientific article published on 8 May 2013

Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues

scientific article

SISH/CISH or qPCR as alternative techniques to FISH for determination of HER2 amplification status on breast tumors core needle biopsies: a multicenter experience based on 840 cases

scientific article

Similar NF-κB gene signatures in TNF-α treated human endothelial cells and breast tumor biopsies.

scientific article

Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer

Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon.

scientific article

Unraveling the Role of Huntingtin in Breast Cancer Metastasis

scientific article published on 20 August 2015

Vandetanib as a potential new treatment for estrogen receptor-negative breast cancers.

scientific article

Variations in the mRNA expression of poly(ADP-ribose) polymerases, poly(ADP-ribose) glycohydrolase and ADP-ribosylhydrolase 3 in breast tumors and impact on clinical outcome.

scientific article published on 9 August 2013

Vasculature analysis of patient derived tumor xenografts using species-specific PCR assays: evidence of tumor endothelial cells and atypical VEGFA-VEGFR1/2 signalings

scientific article

miRNA expression profiling of inflammatory breast cancer identifies a 5‐miRNA signature predictive of breast tumor aggressiveness ⬇️

scientific article published on April 13, 2013

microRNA expression profile in a large series of bladder tumors: Identification of a 3‐miRNA signature associated with aggressiveness of muscle‐invasive bladder cancer ⬇️

scientific article published on February 25, 2013

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