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List of works by David Rabuka

A Pictet-Spengler ligation for protein chemical modification

scientific article published on 13 December 2012

A chemical reporter strategy to probe glycoprotein fucosylation

scientific article published on September 2006

A modular approach for assembling aldehyde-tagged proteins on DNA scaffolds

scientific article published on 25 July 2014

A simple LC/MRM-MS-based method to quantify free linker-payload in antibody-drug conjugate preparations

scientific article published in June 2016

Aldehyde tag coupled with HIPS chemistry enables the production of ADCs conjugated site-specifically to different antibody regions with distinct in vivo efficacy and PK outcomes

scientific article

An efficient entry to new sugar modified ketolide antibiotics

article by Alex Romero et al published February 2005 in Tetrahedron Letters

An emerging playbook for antibody-drug conjugates: lessons from the laboratory and clinic suggest a strategy for improving efficacy and safety

scientific article published on 21 August 2015

CAT-02-106, a Site-Specifically Conjugated Anti-CD22 Antibody Bearing an MDR1-Resistant Maytansine Payload Yields Excellent Efficacy and Safety in Preclinical Models

scientific article published on 15 November 2017

Chemoenzymatic methods for site-specific protein modification ⬇️

scientific article published on October 26, 2010

Control of the molecular orientation of membrane-anchored biomimetic glycopolymers

scientific article published on July 2009

Corrigendum: Synthesis and Microcontact Printing of Dual End-Functionalized Mucin-like Glycopolymers for Microarray Applications

scientific article published in August 2012

Dimeric Aminoglycosides as Antibiotics

Dimeric aminoglycosides as antibiotics.

scientific article

Exploring the effects of linker composition on site-specifically modified antibody-drug conjugates

scientific article published on 23 August 2014

Generating aldehyde-tagged antibodies with high titers and high formylglycine yields by supplementing culture media with copper(II).

scientific article

Generating site-specifically modified proteins via a versatile and stable nucleophilic carbon ligation

scientific article

Glyco-optimization of aminoglycosides: new aminoglycosides as novel anti-infective agents

scientific article published in July 2004

Hierarchical assembly of model cell surfaces: synthesis of mucin mimetic polymers and their display on supported bilayers

scientific article published on 11 April 2007

Hydrazino-Pictet-Spengler Ligation as a Biocompatible Method for the Generation of Stable Protein Conjugates ⬇️

scientific article published on June 3, 2013

Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates

scientific article published on 13 April 2017

Interfacing carbon nanotubes with living cells

scientific article published in May 2006

Leveraging Formylglycine-Generating Enzyme for Production of Site-Specifically Modified Bioconjugates

scientific article published in January 2018

Molecular orientation of membrane-anchored mucin glycoprotein mimics

scientific article

Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes

scientific article

Recent Developments in ADC Technology: Preclinical Studies Signal Future Clinical Trends

scientific article published on 8 November 2017

Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion

scientific article published on 30 April 2015

Saccharide display on microtiter plates

scientific article

Site-Specific Tandem Knoevenagel Condensation-Michael Addition To Generate Antibody-Drug Conjugates

scientific article published on 30 August 2016

Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag

scholarly article

Site-specific chemical protein conjugation using genetically encoded aldehyde tags

scientific article

Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities

scientific article

Synthesis and NMR characterization of the six regioisomeric monophosphates of octyl beta-D-galactopyranosyl-(1 --> 4)-2-acetamido-2-deoxy-beta-D-glucopyranoside

scientific article published on 01 November 2002

Synthesis and microcontact printing of dual end-functionalized mucin-like glycopolymers for microarray applications

scientific article published on January 2009

Synthesis of O-glycolyl-linked neuraminic acids through a spirocyclic intermediate

scientific article published on 01 September 2002

Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag

scientific article

Synthetic trehalose glycolipids confer desiccation resistance to supported lipid monolayers

scientific article published on May 2009

The Mycobacterium tuberculosis virulence factor trehalose dimycolate imparts desiccation resistance to model mycobacterial membranes

scientific article published on 7 March 2008

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