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List of works by Zhenkun Lou

A novel UCHL inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair

scientific article published on 21 May 2019

ATR Inhibition Is a Promising Radiosensitizing Strategy for Triple-Negative Breast Cancer

Author Correction: Regulation of sister chromatid cohesion by nuclear PD-L1

scientific article published on 07 July 2020

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.

scientific article published on 09 January 2017

DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells

scientific article published on 30 October 2020

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

scientific article published on 30 April 2018

Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study

scientific article published on 6 December 2017

Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents

scientific article published on 11 September 2020

L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage

scientific article published on 26 March 2018

Regulation of sister chromatid cohesion by nuclear PD-L1

scientific article published on 29 April 2020

STK38 promotes ATM activation by acting as a reader of histone H4 ufmylation

scientific article published on 03 June 2020

The AMPK-Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome

scientific article published on 29 July 2019

The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53

scientific article published on 07 May 2020

The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair

scientific article published on 26 May 2020

The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization.

scientific article published on 16 February 2018

Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway

scientific article published on 30 August 2018

UFL1 promotes histone H4 ufmylation and ATM activation

scientific article published on 18 March 2019

USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization

scientific article published on 04 June 2018

USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling.

scientific article

USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP

scientific article published on 23 October 2020

ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex

scientific article published on 22 November 2019

ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage

scientific article published in Nature Communications