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List of works by Sylvain Chemtob

A critical role of interleukin-1 in preterm labor.

scientific article

A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway

scientific article

A novel mechanism for vasoconstrictor action of 8-isoprostaglandin F2 alpha on retinal vessels

scientific article published on 01 May 1998

Agonist-independent nuclear localization of the Apelin, angiotensin AT1, and bradykinin B2 receptors

scientific article (publication date: 27 February 2004)

Alterations in the electroretinogram of newborn piglets by propionic acid-derivative nonsteroidal antiinflammatory drugs but not by indomethacin and diclofenac

scientific article published on 01 January 1995

Altered gene expression in cells from patients with lysosomal storage disorders suggests impairment of the ubiquitin pathway

scientific article published on 4 August 2006

Altered vascular function in fetal programming of hypertension

scientific article published in December 2002

Alternating sequential dosing with furosemide and ethacrynic acid in drug tolerance in the newborn

scientific article published on 01 July 1989

An allosteric interleukin-1 receptor modulator mitigates inflammation and photoreceptor toxicity in a model of retinal degeneration

scientific article published on 27 November 2020

Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny

scientific article published in Scientific Reports

Antenatal Suppression of IL-1 Protects against Inflammation-Induced Fetal Injury and Improves Neonatal and Developmental Outcomes in Mice

scientific article published on February 2017

Antiangiogenic activity of aganirsen in nonhuman primate and rodent models of retinal neovascular disease after topical administration.

scientific article

Augmented vasoconstriction and thromboxane formation by 15-F(2t)-isoprostane (8-iso-prostaglandin F(2alpha)) in immature pig periventricular brain microvessels

scientific article published on February 2000

Author Correction: Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny

scientific article published on 15 April 2020

CD36 Deficiency Inhibits Retinal Inflammation and Retinal Degeneration in Cx3cr1 Knockout Mice

scientific article published on 01 January 2019

CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents

scientific article (publication date: February 2008)

CD36 plays an important role in the clearance of oxLDL and associated age-dependent sub-retinal deposits.

scientific article published on December 2010

CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.

scientific article

Changes in body water compartments with diuretic therapy in infants with chronic lung disease

scientific article published on 01 April 1997

Changes in cerebrovascular prostaglandins and thromboxane as a function of systemic blood pressure. Cerebral blood flow autoregulation of the newborn

scientific article published on 01 September 1990

Characterization and ontogeny of PGE2 and PGF2 alpha receptors on the retinal vasculature of the pig

scientific article published on 01 November 1995

Characterization and regulation of prostaglandin E2 receptor and receptor-coupled functions in the choroidal vasculature of the pig during development

scientific article published on 01 April 1997

Characterization of PGE2 receptors in fetal and newborn lamb ductus arteriosus

scientific article

Characterization of alpha 1 D-adrenoceptor subtype in rat myocardium, aorta and other tissues

scientific article published on September 1996

Characterization of the vasorelaxant activity of tyramine and other phenylethylamines in rat aorta

scientific article published on 01 June 1995

Choroid sprouting assay: an ex vivo model of microvascular angiogenesis

scientific article

Choroidal Involution Is Associated with a Progressive Degeneration of the Outer Retinal Function in a Model of Retinopathy of Prematurity: Early Role for IL-1β.

scientific article published on 18 October 2016

Choroidal involution is a key component of oxygen-induced retinopathy

scientific article published on 05 August 2011

Correction: Choroid Sprouting Assay: An Ex Vivo Model of Microvascular Angiogenesis.

scientific article published on 13 August 2013

Correction: Intracrine signaling through lipid mediators and their cognate nuclear G-protein-coupled receptors: a paradigm based on PGE2, PAF, and LPA1 receptors

scientific article published on 07 May 2020

Cytotoxicity of the E(2)-isoprostane 15-E(2t)-IsoP on oligodendrocyte progenitors

scientific article

Deficiency in the metabolite receptor SUCNR1 (GPR91) leads to outer retinal lesions.

scientific article published on June 2013

Development of a novel noncompetitive antagonist of IL-1 receptor

scientific article published on 01 May 2008

Developmental regulation of endothelial nitric oxide synthase in cerebral vessels of newborn pig by prostaglandin E(2)

scientific article

Developmental regulation of prostaglandin E2 synthase in porcine ductus arteriosus

scientific article

Developmentally increased cerebrovascular NO in newborn pigs curtails cerebral blood flow autoregulation

scientific article

Dominant role for calpain in thromboxane-induced neuromicrovascular endothelial cytotoxicity

scientific article

Early ibuprofen administration to prevent patent ductus arteriosus in premature newborn infants

scientific article

Effect of indomethacin on cerebral blood flow velocity of premature newborns

scientific article published in January 1988

Effects of early reduced light exposure on central visual development in preterm infants

scientific article published on 01 April 1999

Eicosanoid-dependent and endothelium-independent oscillations of rat aorta

scientific article published on 01 May 1992

Enhancing the Flexibility and Adaptability of the Darc Structural Representation for Computer-Aided Drug Design ⬇️

scientific article published on January 1, 1998

Epidemiology and pathophysiology of retinopathy of prematurity

scientific article

Examination of the active secondary structure of the peptide 101.10, an allosteric modulator of the interleukin-1 receptor, by positional scanning using β-amino γ-lactams

scientific article published on 04 February 2011

Exploring the relationship between turn geometry and allosteric antagonism of peptide mimic ligands for the prostaglandin F2alpha receptor

scientific article published in January 2009

Exposure of developing oligodendrocytes to cadmium causes HSP72 induction, free radical generation, reduction in glutathione levels, and cell death

scientific article published in November 2000

Expression of cyclooxygenases in ductus arteriosus of fetal and newborn pigs

scientific article published on 01 December 1998

Factors that increase the contractile tone of the ductus arteriosus also regulate its anatomic remodeling

scientific article published in July 2001

Fatty acid receptor Gpr40 mediates neuromicrovascular degeneration induced by transarachidonic acids in rodents

scientific article

Field stimulation-induced tetrodotoxin-resistant vasorelaxation is mediated by sodium hypochlorite

scientific article published in November 2006

Furosemide and ethacrynic acid: risk factors for the occurrence of serum electrolyte abnormalities and metabolic alkalosis in newborns and infants

scientific article published on 01 January 1989

G-protein-coupled receptors signalling at the cell nucleus: an emerging paradigm.

scientific article published on March 2006

G-protein-coupled receptors, channels, and Na+-H+ exchanger in nuclear membranes of heart, hepatic, vascular endothelial, and smooth muscle cells

scientific article published on March 2006

Ghrelin Modulates Physiologic and Pathologic Retinal Angiogenesis through GHSR-1a ⬇️

scientific article published on July 23, 2011

Hydrogen Sulfide Delays LPS-Induced Preterm Birth in Mice via Anti-Inflammatory Pathways

scientific article

Hypercapnia prevents neovascularization via nitrative stress

scientific article published on 14 November 2005

Hypercapnia- and trans-arachidonic acid-induced retinal microvascular degeneration: implications in the genesis of retinopathy of prematurity

scientific article published on June 2006

Hypercapnia- and trans-arachidonic acid-induced retinal microvascular degeneration: implications in the genesis of retinopathy of prematurity

scientific article published in November 2007

Hypoxia up-regulates CD36 expression and function via hypoxia-inducible factor-1- and phosphatidylinositol 3-kinase-dependent mechanisms

scientific article published on 29 July 2009

IL23R (Interleukin 23 Receptor) Variants Protective against Inflammatory Bowel Diseases (IBD) Display Loss of Function due to Impaired Protein Stability and Intracellular Trafficking

scientific article published on 17 February 2016

Immunometabolic modulation of retinal inflammation by CD36 ligand

scientific article published on 09 September 2019

Increased nitric oxide synthesis and action preclude choroidal vasoconstriction to hyperoxia in newborn pigs

scientific article published on 01 September 1996

Increased platelet-activating factor-induced periventricular brain microvascular constriction associated with immaturity

scientific article published in April 2003

Increased thromboxane-mediated contractions of retinal vessels of newborn pigs to peroxides

scientific article published on 01 February 1995

Indomethacin compromises hemodynamics during positive-pressure ventilation, independently of prostanoids

scientific article published on 01 April 1993

Induced and spontaneous colitis mouse models reveal complex interactions between IL-10 and IL-12/IL-23 pathways

scientific article published on 31 May 2019

Inflammatory Amplification: A Central Tenet of Uterine Transition for Labor ⬇️

journal article from 'Frontiers in Cellular and Infection Microbiology' published in 2021

Inflammatory lipid mediators in ischemic retinopathy

scientific article

Influences of Histidine-1 and Azaphenylalanine-4 on the Affinity, Anti-inflammatory, and Antiangiogenic Activities of Azapeptide Cluster of Differentiation 36 Receptor Modulators.

scientific article

Insertion of multiple alpha-amino gamma-lactam (Agl) residues into a peptide sequence by solid-phase synthesis on synphase lanterns.

scientific article published in January 2010

Interleukin-1 Receptor Modulation Using β-Substituted α-Amino-γ-Lactam Peptides From Solid-Phase Synthesis and Diversification

scientific article published on 21 December 2020

Interleukin-1 and ischemic brain injury in the newborn: development of a small molecule inhibitor of IL-1 receptor

scientific article

Interleukin-1β inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration.

scientific article published on May 2011

Intracellular signaling of lipid mediators via cognate nuclear G protein-coupled receptors

scientific article

Intracellular-specific colocalization of prostaglandin E2 synthases and cyclooxygenases in the brain

scientific journal article

Intracrine signaling through lipid mediators and their cognate nuclear G-protein-coupled receptors: a paradigm based on PGE2, PAF, and LPA1 receptors.

scientific article published on March 2006

Inverse agonist activities of beta-adrenoceptor antagonists in rat myocardium

scientific article published on June 1999

Ischemic Retinopathies: Oxidative Stress and Inflammation.

scientific article published on 19 December 2017

Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A

scientific article

Isomer-specific contractile effects of a series of synthetic f2-isoprostanes on retinal and cerebral microvasculature.

scientific article published in January 2004

Key role for cyclooxygenase-2 in PGE2and PGF2αreceptor regulation and cerebral blood f low of the newborn ⬇️

scientific article published on October 1, 1997

Lactate produced during labor modulates uterine inflammation via GPR81 (HCA1)

scientific article

Landscape of Preterm Birth Therapeutics and a Path Forward ⬇️

journal article from 'Journal of Clinical Medicine' published in 2021

Localization of functional prostaglandin E2 receptors EP3 and EP4 in the nuclear envelope

scientific article

Lymphocytic Microparticles Modulate Angiogenic Properties of Macrophages in Laser-induced Choroidal Neovascularization

scientific article

Lysophosphatidic acid induces endothelial cell death by modulating the redox environment.

scientific article published on 22 November 2006

Major role for neuronal NO synthase in curtailing choroidal blood flow autoregulation in newborn pig.

scientific article published in October 2001

Mechanism of the negative inotropic effects of alpha 1-adrenoceptor agonists on mouse myocardium

scientific article published in August 2003

Mechanisms of the biphasic effects of peroxides on the retinal vasculature of newborn and adult pigs

scientific article published on 01 September 1995

Microglia and interleukin-1β in ischemic retinopathy elicit microvascular degeneration through neuronal semaphorin-3A.

scientific article published on 13 June 2013

Modulation of pro-inflammatory gene expression by nuclear lysophosphatidic acid receptor type-1.

scientific article published on 7 July 2003

Multifactorial contributions to WINROP to enhance prediction of severe retinopathy of prematurity

scientific article published on 17 February 2019

Neovascularization in retinopathy of prematurity: opposing actions of neuronal factors GPR91 and semaphorins 3A ⬇️

scientific article published on 05 May 2012

New insights into the retinal circulation: inflammatory lipid mediators in ischemic retinopathy

scientific article

Nitric oxide signaling via nuclearized endothelial nitric-oxide synthase modulates expression of the immediate early genes iNOS and mPGES-1.

scientific article published on 30 March 2006

Novel Anti-Interleukin-1β Therapy Preserves Retinal Integrity: A Longitudinal Investigation Using OCT Imaging and Automated Retinal Segmentation in Small Rodents

scientific article published on 12 March 2020

Novel Noncompetitive IL-1 Receptor-Biased Ligand Prevents Infection- and Inflammation-Induced Preterm Birth

scientific article published on 24 August 2015

Nuclear localization of prostaglandin E2 receptors

scientific article

Nuclear prostaglandin signaling system: biogenesis and actions via heptahelical receptors ⬇️

scientific article published on February 1, 2003

Ontogeny of positive inotropic responses to sympathomimetic agents and of myocardial adrenoceptors in rats

scientific article published on 01 April 1994

PGE(2)-mediated eNOS induction in prolonged hypercapnia

scientific article published in May 2002

PGE2, via EP3 receptors, regulates brain nitric oxide synthase in the perinatal period.

scientific article published in December 1998

Peroxide-cyclooxygenase interactions in postasphyxial changes in retinal and choroidal hemodynamics ⬇️

scientific article published on June 1, 1995

Persistent functional and structural retinal anomalies in newborn rats exposed to hyperoxia

scientific article published on 01 January 1999

Platelet Activating Factor Receptors ⬇️

scientific article published on 01 January 2003

Platelet-activating factor in vasoobliteration of oxygen-induced retinopathy.

scientific article published in October 2002

Positional scanning for peptide secondary structure by systematic solid-phase synthesis of amino lactam peptides

scientific article

Postmenopausal hormone therapy increases retinal blood flow and protects the retinal nerve fiber layer

scientific article

Postnatal hyperoxia and the developing rat retina: beyond the obvious vasculopathy.

scientific article published on 10 December 2009

Postnatal weight gain modifies severity and functional outcome of oxygen-induced proliferative retinopathy.

scientific article

Preservation of neural function in the perinate by high PGE(2) levels acting via EP(2) receptors

scientific article published on 01 August 2000

Prevention of postasphyxia electroretinal dysfunction with a pyridoxal hydrazone

scientific article published on 01 January 1997

Proangiogenic effects of protease-activated receptor 2 are tumor necrosis factor-alpha and consecutively Tie2 dependent

scientific journal article

Probing Anti-inflammatory Properties Independent of NF-κB Through Conformational Constraint of Peptide-Based Interleukin-1 Receptor Biased Ligands

article

Proinflammatory gene induction by platelet-activating factor mediated via its cognate nuclear receptor

scientific article published in December 2002

Proliferative retinopathies: angiogenesis that blinds

scientific article published on 15 October 2009

Propranolol Attenuates Proangiogenic Activity of Mononuclear Phagocytes: Implication in Choroidal Neovascularization

scientific article published on 01 November 2019

Prostaglandin G/H Synthase-2 Is a Major Contributor of Brain Prostaglandins in the Newborn ⬇️

scientific article published on October 13, 1995

Prostanoids determine the range of cerebral blood flow autoregulation of newborn piglets

scientific article published in May 1990

Redox-dependent effects of nitric oxide on microvascular integrity in oxygen-induced retinopathy.

scientific article published in December 2004

Reduced responses of retinal vessels of the newborn pig to prostaglandins but not to thromboxane

scientific article published on 01 February 1994

Regulation of cerebrovascular prostaglandin E2 (PGE2) and PGF2 alpha receptors and their functions during development

scientific article published on 01 June 1996

Regulation of eNOS expression in brain endothelial cells by perinuclear EP(3) receptors

scientific article

Regulation of endothelial nitric oxide synthase by PGD(2) in the developing choroid

scientific article

Regulation of prostanoid vasomotor effects and receptors in choroidal vessels of newborn pigs

scientific article published on 01 March 1997

Relationship between Circulating Platelet Counts and Ductus Arteriosus Patency after Indomethacin Treatment ⬇️

scientific article published on December 30, 2010

Relationship of 2,3-Diphosphoglycerate and 2,3-Diphosphoglycerate Mutase in Various Mammals ⬇️

scientific article published on January 1, 1980

Responses of placental arteries from normotensive and preeclamptic women to endogenous vasoactive agents ⬇️

scientific article published on 01 March 1993

Restoration of renal function by a novel prostaglandin EP4 receptor-derived peptide in models of acute renal failure.

scientific article published on 14 November 2012

Retinopathy of prematurity: inflammation, choroidal degeneration, and novel promising therapeutic strategies

scientific article published on 22 August 2017

Retinopathy of prematurity: understanding ischemic retinal vasculopathies at an extreme of life

scientific article

Role of receptor-mediated endocytosis in the antiangiogenic effects of human T lymphoblastic cell-derived microparticles

scientific article

Role of thromboxane in retinal microvascular degeneration in oxygen-induced retinopathy

scientific article

Selective neuromicrovascular endothelial cell death by 8-Iso-prostaglandin F2alpha: possible role in ischemic brain injury

scientific article published on 20 February 2003

Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response

scientific article published on 20 August 2014

Sterile inflammation and pregnancy complications: a review

scientific article

Stimulation of prostaglandin G/H synthase‐2 expression by arachidonic acid monoxygenase product, 14,15‐epoxyeicosatrienoic acid ⬇️

scientific article published on October 27, 1997

Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis

scientific article published on 14 September 2014

Sustained hypercapnia induces cerebral microvascular degeneration in the immature brain through induction of nitrative stress

scientific article published on 31 March 2010

Syndrome of inappropriate secretion of antidiuretic hormone in enteroviral meningitis

scientific article published on 01 March 1985

THG113: a novel selective FP antagonist that delays preterm labor

scientific article published on December 2002

The Inability of the Choroid to Revascularize in Oxygen-Induced Retinopathy Results from Increased p53/miR-Let-7b Activity

scientific article published on 17 August 2019

The determinant role of IL-6 in the establishment of inflammation leading to spontaneous preterm birth ⬇️

journal article from 'Cytokine & Growth Factor Reviews' published in 2021

The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation

scientific article

The effect of oxygen and light on the structure and function of the neonatal rat retina.

scientific article published on 16 May 2008

The pharmacologic closure of the patent ductus arteriosus

scientific article

The role of lysophosphatidic acid receptor (LPA1) in the oxygen-induced retinal ganglion cell degeneration

scientific journal article

The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis

scientific article published on 5 October 2008

Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration

scientific article published on 27 November 2005

Trans-arachidonic acids: new mediators of nitro-oxidative stress

scientific article published on 27 May 2008

Understanding ischemic retinopathies: emerging concepts from oxygen-induced retinopathy.

scientific article published on 31 October 2009

Understanding retinopathy of prematurity: update on pathogenesis

scientific article

Uterotonic Neuromedin U Receptor 2 and Its Ligands Are Upregulated by Inflammation in Mice and Humans, and Elicit Preterm Birth ⬇️

scientific article

VEGFR-1: a safe target for prophylaxis of retinopathy of prematurity?

scientific article published on 19 November 2003

VRQ397 (CRAVKY): a novel noncompetitive V2 receptor antagonist

scientific article

p75 neurotrophin receptor participates in the choroidal antiangiogenic and apoptotic effects of T-lymphocyte-derived microparticles

scientific journal article

trans-Arachidonic acids induce a heme oxygenase-dependent vasorelaxation of cerebral microvasculature.

scientific article

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