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List of works by Franciszek K Główka

11β-Hydroxysteroid Dehydrogenase 2 in Preeclampsia

scientific article

11β-Hydroxysteroid dehydrogenase type 2 in hypertension: comparison of phenotype and genotype analysis

scientific article published on 10 January 2013

Activation of Prodrug Treosulfan at pH 7.4 and 37°C Accompanied by Hydrolysis of Its Active Epoxides: Kinetic Studies with Clinical Relevance

scientific article published on 30 September 2015

Assessment of the Risk of Rhabdomyolysis and Myopathy During Concomitant Treatment with Ticagrelor and Statins

scientific article published on 01 July 2018

Bioavailability of gliclazide from some formulation tablets

scientific article published in October 1998

Bioavailability of mesalazine from two coated formulation tablets

scientific article published on 28 February 2019

Bioavailability of moclobemide from two formulation tablets in healthy humans

scientific article published on 01 February 2019

Bioavailability of propylthiouracil from two formulation tablets

scientific article published on 01 December 2018

Bupivacaine administered intrathecally versus rectally in the management of intractable rectal cancer pain in palliative care

scientific article

CE Determination of Ketoprofen Enantiomers in Clinical Samples of Plasma, Synovial Fluid and Urine

scientific article published on 4 January 2008

Capillary zone electrophoresis method for determination of (+)-S clopidogrel carboxylic acid metabolite in human plasma and urine designed for biopharmaceutic studies

scientific article published on 6 March 2010

Clinical bioanalysis of treosulfan and its epoxides: The importance of collected blood processing for valid pharmacokinetic results.

scientific article published on 24 February 2018

Clinical pharmacokinetics of clopidogrel and its metabolites in patients with cardiovascular diseases

scientific article published on February 2014

Clinical pharmacokinetics of ketoprofen enantiomers in wild type of Cyp 2c8 and Cyp 2c9 patients with rheumatoid arthritis

scientific article

Correction to: Population pharmacokinetic approach for evaluation of treosulfan and its active monoepoxide disposition in plasma and brain on the basis of a rat model

scientific article published on 12 August 2020

Cortisol metabolism in pregnancies with small for gestational age neonates

scientific article published on 29 November 2019

DISSOLUTION KINETICS STUDIES OF CLOPIDOGREL FROM SELECTED MULTISOURCE COATED TABLETS WITH APPLICATION OF CAPILLARY ZONE ELECTROPHORESIS METHOD.

scientific article published in January 2016

Detailed analysis of cortisol, cortisone and their tetrahydro- and allo-tetrahydrometabolites in human urine by LC-MS/MS.

scientific article published on 21 March 2017

Determinants of high on-treatment platelet reactivity and agreement between VerifyNow and Multiplate assays

scientific article published on 24 February 2017

Determination of ketoprofen enantiomers in human serum by capillary zone electrophoresis: man pharmacokinetic studies after administration of rac-ketoprofen tablets

scientific article published in November 2002

Determination of partition coefficients n-octanol/water for treosulfan and its epoxy-transformers: an example of a negative correlation between lipophilicity of unionized compounds and their retention in reversed-phase chromatography.

scientific article published on 19 February 2013

Determination of prodrug treosulfan and its biologically active monoepoxide in rat plasma, liver, lungs, kidneys, muscle, and brain by HPLC-ESI-MS/MS method

scientific article published on 18 March 2017

Determination of roxithromycin in human plasma by HPLC with fluorescence and UV absorbance detection: application to a pharmacokinetic study

scientific article published on 20 February 2007

Determination of total and free voriconazole in human plasma: Application to pharmacokinetic study and therapeutic monitoring

scientific article published on 25 October 2019

Determination of treosulfan in plasma and urine by HPLC with refractometric detection; pharmacokinetic studies in children undergoing myeloablative treatment prior to haematopoietic stem cell transplantation

scientific article published on 22 December 2006

Development of a Limited Sampling Strategy for the Estimation of Exposure to High-Dose Etoposide After Intravenous Infusion in Pediatric Patients.

scientific article published on 20 December 2016

Development of an LC-MS/MS method for simultaneous determination of ticagrelor and its active metabolite during concomitant treatment with atorvastatin

scientific article published on 16 December 2018

Direct high-performance liquid chromatography method with refractometric detection designed for stability studies of treosulfan and its biologically active epoxy-transformers.

scientific article published on 16 October 2012

Disposition of treosulfan and its active monoepoxide in a bone marrow, liver, lungs, brain, and muscle: Studies in a rat model with clinical relevance.

scientific article published on 12 September 2017

Effect of Temperature on the Kinetics of the Activation of Treosulfan and Hydrolytic Decomposition of Its Active Epoxy Derivatives.

scientific article published on 6 June 2017

Enantioselective CE method for pharmacokinetic studies on ibuprofen and its chiral metabolites with reference to genetic polymorphism

scientific article published on 01 August 2007

FC33 dose-dependent first-order elimination of racemic ibuprofen in rabbits

scientific article published in September 1994

Formation Rate-Limited Pharmacokinetics of Biologically Active Epoxy Transformers of Prodrug Treosulfan

scientific article published on 01 April 2016

Genetic Determinants of Vitamin D-Related Disorders; Focus on Vitamin D Receptor

scientific article published on 01 January 2018

Genetic and non-genetic factors affecting the response to clopidogrel therapy.

scientific article published on 07 March 2012

Genetic factors influencing efficacy of clopidogrel treatment

scientific article

Glucocorticoid Metabolism in Hypertensive Disorders of Pregnancy: Analysis of Plasma and Urinary Cortisol and Cortisone.

scientific article published on 4 December 2015

HPCE AND HPLC METHODS FOR DETERMINATION OF CLOPIDOGREL AND ITS CARBOXYLIC ACID METABOLITE IN BIOLOGICAL SAMPLES: A COMPARATIVE ANALYSIS

HPLC Analysis of the Urinary Iodine Concentration in Pregnant Women

scientific article published on 10 November 2021

HPLC method for determination of biologically active epoxy-transformers of treosulfan in human plasma: pharmacokinetic application

scientific article published on 24 December 2011

HPLC method for determination of fluorescence derivatives of cortisol, cortisone and their tetrahydro- and allo-tetrahydro-metabolites in biological fluids

scientific article published on 26 November 2009

HPLC–MS/MS method for the simultaneous determination of clopidogrel, its carboxylic acid metabolite and derivatized isomers of thiol metabolite in clinical samples

scientific article published on 12 November 2012

HSD11B2, RUNX3, and LINE-1 Methylation in Placental DNA of Hypertensive Disorders of Pregnancy Patients.

scientific article

High performance capillary electrophoresis for determination of the enantiomers of 2-arylpropionic acid derivatives in human serum. Pharmacokinetic studies of ketoprofen enantiomers following administration of standard and sustained release tablets.

scientific article

High performance capillary electrophoresis method for determination of ibuprofen enantiomers in human serum and urine

scientific article published in May 2005

High-dose treosulfan in conditioning prior to hematopoietic stem cell transplantation ⬇️

scientific article published on October 1, 2010

High-performance liquid chromatography methods for the analysis of endogenous cortisol and cortisone in human urine: comparison of mass spectrometry and fluorescence detection

scientific article published on 25 June 2018

Impact of CYP3A4*1G Allele on Clinical Pharmacokinetics and Pharmacodynamics of Clopidogrel

scientific article published on 18 February 2016

Impact of common ABCB1 polymorphism on pharmacokinetics and pharmacodynamics of clopidogrel and its metabolites

scientific article published on 28 November 2014

Impact of genetic variants of selected cytochrome P450 isoenzymes on pharmacokinetics and pharmacodynamics of clopidogrel in patients co-treated with atorvastatin or rosuvastatin

scientific article published on 02 January 2020

In Vitro Study of the Enzymatic and Nonenzymatic Conjugation of Treosulfan with Glutathione

scientific article published on 01 October 2019

In Vivo Red Blood Cells/Plasma Partition Coefficient of Treosulfan and Its Active Monoepoxide in Rats.

scientific article published in October 2018

Increased cortisol metabolism in women with pregnancy-related hypertension.

scientific article published on 2 April 2018

Influence of genetic co-factors on the population pharmacokinetic model for clopidogrel and its active thiol metabolite.

scientific article published on 15 September 2017

Influence of statin treatment on pharmacokinetics and pharmacodynamics of clopidogrel and its metabolites in patients after coronary angiography/angioplasty

scientific article published on 25 May 2019

Kinetic and Mechanistic Study of the pH-Dependent Activation (Epoxidation) of Prodrug Treosulfan Including the Reaction Inhibition in a Borate Buffer

scientific article published on 22 March 2017

Kinetics of in Vitro Guanine- N7-Alkylation in Calf Thymus DNA by (2 S,3 S)-1,2-Epoxybutane-3,4-diol 4-methanesulfonate and (2 S,3 S)-1,2:3,4-Diepoxybutane: Revision of the Mechanism of DNA Cross-Linking by the Prodrug Treosulfan

scientific article published on 03 May 2019

LC procedure with SPE for quantification of indobufen enantiomers: pharmacokinetic studies

scientific article published on 01 February 2000

Liquid chromatography-tandem mass spectrometry method for simultaneous determination of three N-7-guanine adducts of the active epoxides of prodrug treosulfan in DNA in vitro

scientific article published on 08 February 2019

Lumbar paravertebral blockade as intractable pain management method in palliative care.

scientific article

Maternal Serum Endocan Concentration in Pregnancies Complicated by Intrauterine Growth Restriction

scientific article published on 09 May 2018

Measurement of plasma 25-hydroxyvitamin D2, 25-hydroxyvitamin D3 and 3-epi-25-hydroxyvitamin D3 in population of patients with cardiovascular disease by UPLC-MS/MS method

scientific article published on 29 August 2020

Modulatory effect of chiral nonsteroidal anti-inflammatory drugs on apoptosis of human neutrophils.

scientific article

N-7-Guanine Adduct of the Active Monoepoxide of Prodrug Treosulfan: First Synthesis, Characterization, and Decomposition Profile Under Physiological Conditions

scientific article published on 27 June 2018

New Methods Used in Pharmacokinetics and Therapeutic Monitoring of the First and Newer Generations of Antiepileptic Drugs (AEDs)

scientific article published on 02 November 2020

Ocular disposition of treosulfan and its active epoxy-transformers following intravenous administration in rabbits.

scientific article published on 14 July 2016

Penetration of Treosulfan and its Active Monoepoxide Transformation Product into Central Nervous System of Juvenile and Young Adult Rats.

scientific article

Pharmacokinetic Drug-Drug Interactions among Antiepileptic Drugs, Including CBD, Drugs Used to Treat COVID-19 and Nutrients

scientific article published on 3 September 2021

Pharmacokinetic Interaction between Sorafenib and Atorvastatin, and Sorafenib and Metformin in Rats

scientific article published on 28 June 2020

Pharmacokinetic studies of enantiomers of ibuprofen and its chiral metabolites in humans with different variants of genes coding CYP2C8 and CYP2C9 isoenzymes.

scientific article published in June 2009

Pharmacokinetics of high-dose i.v. treosulfan in children undergoing treosulfan-based preparative regimen for allogeneic haematopoietic SCT.

scientific article published on October 2008

Pharmacokinetics of treosulfan and its active monoepoxide in pediatric patients after intravenous infusion of high-dose treosulfan prior to HSCT.

scientific article published on 16 December 2014

Population pharmacokinetic approach for evaluation of treosulfan and its active monoepoxide disposition in plasma and brain on the basis of a rat model

scientific article published on 30 May 2020

Population pharmacokinetics of treosulfan and development of a limited sampling strategy in children prior to hematopoietic stem cell transplantation.

scientific article published on 3 October 2017

Protein binding of indobufen enantiomers: pharmacokinetics of free fraction-studies after single or multiple doses of rac-indobufen

scientific article published in October 2002

RP-HPLC method with fluorescence detection for determination of small quantities of triamcinolone in plasma in presence of endogenous steroids after derivatization with 9-anthroyl nitrile; pharmacokinetic studies

scientific article published on 23 March 2006

Rapid and sensitive liquid chromatography-tandem mass spectrometry method for determination of protein-free pro-drug treosulfan and its biologically active monoepoxy-transformer in plasma and brain tissue.

scientific article published on 4 April 2014

Relationship between exposure to treosulfan and its monoepoxytransformer – An insight from population pharmacokinetic study in pediatric patients before hematopoietic stem cell transplantation

scientific article published on 27 April 2018

Reply to Comment on “Determination of treosulfan in plasma and urine by HPLC with refractometric detection; pharmacokinetic studies in children undergoing myeloablative treatment prior to haematopoietic stem cell transplantation” by G. Hempel and

scientific article published in June 2007

Resolution of indobufen enantiomers by capillary zone electrophoresis. Pharmacokinetic studies of human serum.

scientific article published in April 2004

Serum endocan concentration and its correlation with severity of hypertensive disorders in pregnancy

scientific article published on 2 December 2018

Serum sCD25 Protein as a Predictor of Lack of Long-Term Benefits from Immunotherapy in Non-Small Cell Lung Cancer: A Pilot Study

scientific article published on 23 July 2021

Steady-state pharmacokinetics of indobufen enantiomers in patients with obliterative atherosclerosis

scientific article published on June 2001

Stereoselective CZE method for analysis of verapamil and norverapamil in human plasma

scientific article

Stereoselective pharmacokinetics of ibuprofen and its lysinate from suppositories in rabbits

scientific article published on 01 April 2000

Stereoselective pharmacokinetics of indobufen from tablets and intramuscular injections in man

scientific article published on 01 January 2000

Studies on the metabolism of ibuprofen in isolated rat hepatocytes

scientific article published on 01 May 1997

The Overview on the Pharmacokinetic and Pharmacodynamic Interactions of Triazoles

scientific article published on 19 November 2021

The influence of genetic polymorphism of Cyp2c19 isoenzyme on the pharmacokinetics of clopidogrel and its metabolites in patients with cardiovascular diseases

scientific article published on 06 May 2014

Ticagrelor in modern cardiology - an up-to-date review of most important aspects of ticagrelor pharmacotherapy

scientific article published on 27 December 2017

Treosulfan Pharmacokinetics and its Variability in Pediatric and Adult Patients Undergoing Conditioning Prior to Hematopoietic Stem Cell Transplantation: Current State of the Art, In-Depth Analysis, and Perspectives.

scientific article published on 19 March 2018

Variants of HSD11B2 gene in hypertensive disorders of pregnancy

scientific article published on 10 August 2016

Vitamin D Receptor Gene Polymorphism and Vitamin D Status in Population of Patients with Cardiovascular Disease-A Preliminary Study

scientific article published on 6 September 2021

[Biological availability of ibuprofen in Imbun 500 suppositories]

scientific article published on 01 January 1990

[The in vitro neutralizing efficacy of different dosage forms of antacid preparations]

scientific article published on 01 January 1984

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