List of works by E. Elizabeth Patton

A conditional zebrafish MITF mutation reveals MITF levels are critical for melanoma promotion vs. regression in vivo

scientific article published on 5 July 2013

A novel role for Glucocorticoid-Induced TNF Receptor Ligand (Gitrl) in early embryonic zebrafish development

scientific article published in January 2010

A zebrafish model for nevus regeneration

scientific article published on April 2011

ALDH1 Bio-activates Nifuroxazide to Eradicate ALDH Melanoma-Initiating Cells

scientific article published on 04 October 2018

ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species

scientific article published on 01 November 2020

ALDH2 mediates 5-nitrofuran activity in multiple species

scientific article published on July 2012

Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells

scientific article published in 2022

Assessment of biocompatibility of 3D printed photopolymers using zebrafish embryo toxicity assays.

scientific article published on 08 December 2015

BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.

scientific article published in February 2005

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export

article published in the Proceedings of the National Academy of Sciences of the United States of America

Bright insights into palladium-triggered local chemotherapy

scientific article published on 17 July 2018

Cancer: Trouble upstream

scientific article published in March 2013

Cell signalling: Red alert about lipid's role in skin cancer

scientific article published on 6 September 2017

Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation

scientific article

Continual low-level MEK inhibition ameliorates cardio-facio-cutaneous phenotypes in zebrafish

scientific article

Cross-species models of human melanoma

scientific article

DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans

scientific article

Deciphering melanoma cell states and plasticity with zebrafish models

scientific article published on 16 December 2020

Development and bioorthogonal activation of palladium-labile prodrugs of gemcitabine

scientific article

Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish.

scientific article

Differentiated melanocyte cell division occurs in vivo and is promoted by mutations in Mitf

scientific article

Dopamine from the brain promotes spinal motor neuron generation during development and adult regeneration.

scientific article published on 23 May 2013

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependant pigment progenitors in zebrafish

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish

scientific article published on 27 February 2019

Erratum

Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach.

scientific article

FGFR3 is a positive regulator of osteoblast expansion and differentiation during zebrafish skull vault development

scientific article

Fgfr3 is a positive regulator of osteoblast expansion and differentiation during zebrafish skull vault development

scientific article published on 07 May 2020

Fish from Head to Tail: The 9th European Zebrafish Meeting in Oslo.

scientific article published on 9 February 2016

Fishing for ancestry

scientific article published on 02 August 2018

Generating and analyzing fish models of melanoma.

scientific article published in January 2011

Generation and analysis of zebrafish melanoma models.

scientific article published on 18 April 2016

Genetic and environmental melanoma models in fish

scientific article

Genetic models of cancer in zebrafish

scientific article published on January 2008

Going forward together: cooperative invasion in melanoma

scientific article published on 10 November 2014

Kinase-activating and kinase-impaired cardio-facio-cutaneous syndrome alleles have activity during zebrafish development and are sensitive to small molecule inhibitors

scientific article

Knockdown of the zebrafish ortholog of the retinitis pigmentosa 2 (RP2) gene results in retinal degeneration

scientific article published on 5 May 2011

Let's make it happen: for gender equality in science!

scientific article published on 01 November 2015

Live imaging in zebrafish reveals neu(trophil) insight into the metastatic niche.

scientific article

Location, Location, Location: Spatio-Temporal Cues That Define the Cell of Origin in Melanoma.

scientific article published in November 2017

Long-term non-invasive drug treatments in adult zebrafish that lead to melanoma drug resistance

scientific article published in 2022

Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish.

scientific article published on 14 August 2017

MEK Inhibitors Reverse cAMP-Mediated Anxiety in Zebrafish

scientific article

Melanoma Regression and Recurrence in Zebrafish

scientific article published in January 2016

Melanoma models for the next generation of therapies

Mosaic Activating Mutations in GNA11 and GNAQ Are Associated with Phakomatosis Pigmentovascularis and Extensive Dermal Melanocytosis. ⬇️

scientific article published on 14 January 2016

Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy

scientific article published on 20 February 2018

Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy

scientific article published in November 2018

N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture

scientific article published on 29 July 2014

Notochord Injury Assays that Stimulate Transcriptional Responses in Zebrafish Larvae

article

PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation

scientific article published on 08 July 2020

Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back.

scientific article published in January 2010

Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase

scientific article

Rapid synthesis and zebrafish evaluation of a phenanthridine-based small molecule library

scientific article

Sharing chemical libraries within the European zebrafish community

scientific article published on 01 March 2010

Small molecule screening identifies targetable zebrafish pigmentation pathways.

scientific article

Small molecule screening in zebrafish: an in vivo approach to identifying new chemical tools and drug leads

scientific article

Spontaneously occurring melanoma in animals and their relevance to human melanoma

scientific article published on 11 July 2020

Spotlight on zebrafish: the next wave of translational research

scientific article published on 07 March 2019

Spotlight on zebrafish: translational impact

scientific article published on July 2014

Supporting women in science at PCMR

scientific article published on 01 July 2019

Taking human cancer genes to the fish: a transgenic model of melanoma in zebrafish.

scientific article published in January 2005

Temperature-sensitive splicing of mitfa by an intron mutation in zebrafish

scientific article published on 29 December 2014

The INT6 cancer gene and MEK signaling pathways converge during zebrafish development

scientific article (publication date: 2007)

The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models

scientific article published on January 2013

The melanocyte lineage in development and disease

scientific article

The melanocyte lineage in development and disease

scientific article published on April 2015

The twin pillars of Disease Models & Mechanisms

scientific article

The zebrafish as a model organism to study development of the immune system

scientific article published on January 2003

Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish

scientific article published on 20 April 2009

Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution

scientific article published on 04 June 2020

Wilms Tumor 1b defines a wound-specific sheath cell subpopulation associated with notochord repair.

scientific article

Xmrk in medaka: a new genetic melanoma model

scientific article published on 01 January 2010

Zebrafish MITF-Low Melanoma Subtype Models Reveal Transcriptional Subclusters and MITF-Independent Residual Disease

scientific article published on 03 October 2019

Zebrafish Rpgr is required for normal retinal development and plays a role in dynein-based retrograde transport processes

scientific article published in December 2009

Zebrafish have a competent p53-dependent nucleotide excision repair pathway to resolve ultraviolet B-induced DNA damage in the skin

scientific article

mc1r Pathway regulation of zebrafish melanosome dispersion

scientific article

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