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List of works by Lorraine Pillus

A moonlighting metabolic protein influences repair at DNA double-stranded breaks.

scientific article

A programmable fate decision landscape underlies single-cell aging in yeast

scientific article published on 01 July 2020

A unique class of conditional sir2 mutants displays distinct silencing defects in Saccharomyces cerevisiae.

scientific article

Balancing chromatin remodeling and histone modifications in transcription ⬇️

scientific article published on July 16, 2013

Bypassing the requirement for an essential MYST acetyltransferase.

scientific article

Cell cycle roles for GCN5 revealed through genetic suppression

scientific article published on 13 August 2020

Chromatin Regulation by the NuA4 Acetyltransferase Complex Is Mediated by Essential Interactions Between Enhancer of Polycomb (Epl1) and Esa1.

scientific article

Chromatin-modifiying enzymes are essential when the Saccharomyces cerevisiae morphogenesis checkpoint is constitutively activated

scientific article

Collaboration between the essential Esa1 acetyltransferase and the Rpd3 deacetylase is mediated by H4K12 histone acetylation in Saccharomyces cerevisiae

scientific article published on 13 July 2009

Connecting GCN5's centromeric SAGA to the mitotic tension-sensing checkpoint

scientific article published on 11 July 2018

Conserved locus-specific silencing functions of Schizosaccharomyces pombe sir2+.

scientific article

Critical genomic regulation mediated by Enhancer of Polycomb.

scientific article

Crystal Structure and Functional Analysis of Homocitrate Synthase, an Essential Enzyme in Lysine Biosynthesis ⬇️

scientific article

Decoupling epigenetic and genetic effects through systematic analysis of gene position

scientific article

Distinct roles for the essential MYST family HAT Esa1p in transcriptional silencing

scientific article

Divergent Aging of Isogenic Yeast Cells Revealed through Single-Cell Phenotypic Dynamics

scientific article published on 06 March 2019

Dynamic reprogramming of transcription factors to and from the subtelomere

scientific article published in June 2009

Engineering longevity—design of a synthetic gene oscillator to slow cellular aging

scientific article published on 27 April 2023

Functional Antagonism between Sas3 and Gcn5 Acetyltransferases and ISWI Chromatin Remodelers ⬇️

scientific article published on October 4, 2012

Functional analyses of chromatin modifications in yeast

scientific article published on January 2004

Functions for diverse metabolic activities in heterochromatin

scientific article published on 2 March 2016

Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast

scientific article

Histone H3 phosphorylation can promote TBP recruitment through distinct promoter-specific mechanisms

scientific article

Histone deacetylation by Sir2 generates a transcriptionally repressed nucleoprotein complex

scholarly article

Homocitrate synthase connects amino acid metabolism to chromatin functions through Esa1 and DNA damage

scientific article published on September 2010

Identification of functionally distinct regions that mediate biological activity of the protein kinase a homolog Tpk2.

scientific article published on 30 October 2007

Identifying critical non-catalytic residues that modulate protein kinase A activity

scientific article published in 2009

MYSTs mark chromatin for chromosomal functions

scientific article published on 27 May 2008

Molecular requirements for gene expression mediated by targeted histone acetyltransferases

scientific article published in July 2004

Multigenerational silencing dynamics control cell aging

scientific article

Nuclear export modulates the cytoplasmic Sir2 homologue Hst2.

scientific article

Pho5p and newly identified nucleotide pyrophosphatases/ phosphodiesterases regulate extracellular nucleotide phosphate metabolism in Saccharomyces cerevisiae

scientific article published in November 2005

Phosphorylation of the 19S regulatory particle ATPase subunit, Rpt6, modifies susceptibility to proteotoxic stress and protein aggregation.

scientific article

Promotion of Cell Viability and Histone Gene Expression by the Acetyltransferase Gcn5 and the Protein Phosphatase PP2A in Saccharomyces cerevisiae.

scientific article published on 17 June 2016

STUbLs in chromatin and genome stability ⬇️

scientific article published on February 1, 2013

Slx5 Promotes Transcriptional Silencing and Is Required for Robust Growth in the Absence of Sir2

Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2.

scientific article

Structural Basis for Histone and Phosphohistone Binding by the GCN5 Histone Acetyltransferase ⬇️

scientific article published on August 1, 2003

Structural Basis for L-Lysine Feedback Inhibition of Homocitrate Synthase

scientific article

Suppression Analysis ofesa1Mutants inSaccharomyces cerevisiaeLinksNAB3to Transcriptional Silencing and Nucleolar Functions ⬇️

scientific article published on October 1, 2012

Telomerase-independent proliferation is influenced by cell type in Saccharomyces cerevisiae

scientific article

The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction.

scientific article

The SAGA subunit Ada2 functions in transcriptional silencing

scientific article

The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response

scientific article

The Sir4 C-terminal coiled coil is required for telomeric and mating type silencing in Saccharomyces cerevisiae

scientific article

The glucanosyltransferase Gas1 functions in transcriptional silencing

scientific article

The replicative lifespan-extending deletion of SGF73 results in altered ribosomal gene expression in yeast.

scientific article published on 31 May 2017

Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8.

scientific article

Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation

scientific article published on 24 September 2014

Unexpected function of the glucanosyltransferase Gas1 in the DNA damage response linked to histone H3 acetyltransferases in Saccharomyces cerevisiae

scientific article published on 13 February 2014

WADDINGTON’S LANDSCAPE OF CELL AGING

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

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