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List of works by David J Adams

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

scientific article

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

scientific article published on 12 October 2017

A lentiviral vector-based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma

scientific article published on 19 October 2018

Accelerating functional gene discovery in osteoarthritis

scientific article published on 20 January 2021

Analysis of CRISPR-Cas9 screens identify genetic dependencies in melanoma

scientific article published on 07 August 2020

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

scientific article

Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma

Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice

scientific article

CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation

scientific article published on 23 March 2021

Collateral damage and CRISPR genome editing

scientific article published on 14 March 2019

Common and distinct transcriptional signatures of mammalian embryonic lethality

scientific article published on 26 June 2019

Corrigendum: High-throughput discovery of novel developmental phenotypes.

scientific article published on 8 November 2017

Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer

scientific article published in 2023

Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia

scientific article published on 30 April 2021

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage

scientific article

Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.

scientific article published on 26 June 2017

Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML

scientific article published on 16 March 2020

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

scientific article published on 28 March 2017

Genomic analysis and clinical management of adolescent cutaneous melanoma

scientific article

Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology

scientific article published on 09 November 2020

Genomics in 2011: challenges and opportunities

scientific article published on 28 December 2011

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation

scientific article published on 16 December 2019

Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice

scientific article

Human and mouse essentiality screens as a resource for disease gene discovery

scientific article published on 31 January 2020

Identification of FoxR2 as an oncogene in medulloblastoma

scientific article published on 5 March 2014

Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis

scientific article published on 01 April 2022

Loss of TSLC1 causes male infertility due to a defect at the spermatid stage of spermatogenesis

scientific article

Melanoma predisposition-A limited role for germline BRCA1 and BRCA2 variants

scientific article published on 28 October 2019

Melanoma subtypes: genomic profiles, prognostic molecular markers and therapeutic possibilities

scientific article published on 15 February 2019

Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet

scientific article published in 2024

Mouse genomic variation and its effect on phenotypes and gene regulation

scientific article (publication date: 14 September 2011)

Mouse protein coding diversity: What's left to discover?

scientific article published on 14 November 2019

Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases

scientific article published on 27 August 2020

Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice

scientific article published on 20 January 2020

Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy

scientific article published on 23 July 2020

No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice

scientific article published on 09 July 2018

Normal germ line establishment in mice carrying a deletion of the Ifitm/Fragilis gene family cluster

scientific article published on 27 May 2008

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

scientific article published on 05 May 2021

Pulmonary metastatic colonisation and granulomas in NOX2-deficient mice

scientific article published on 19 September 2018

Revisiting olfactory receptors as putative drivers of cancer

scientific article published on 10 February 2017

Spontaneously occurring melanoma in animals and their relevance to human melanoma

scientific article published on 11 July 2020

Synthetic lethality: emerging targets and opportunities in melanoma

scientific article

The Deep Genome Project

scientific article published on 03 February 2020

The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence

scientific article published on 07 October 2020

The mutational signature profile of known and suspected human carcinogens in mice

scientific article published on 28 September 2020

Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis

scientific article published in 2022

Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression

scientific article published on 5 January 2015

Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells

scientific article

Tumors induce de novo steroid biosynthesis in T cells to evade immunity

scientific article published on 17 July 2020

Tumour gene expression signature in primary melanoma predicts long-term outcomes

scientific article published on 18 February 2021

ZMYM2 inhibits NANOG-mediated reprogramming

scientific article published on 06 June 2019

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