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List of works by Jochen Herms

4D in in vivo 2-photon laser scanning fluorescence microscopy with sample motion in 6 degrees of freedom

scientific article

5‐Aminolevulinic Acid‐induced Protoporphyrin IX Levels in Tissue of Human Malignant Brain Tumors ⬇️

scientific article published on September 20, 2010

A30P α-Synuclein interferes with the stable integration of adult-born neurons into the olfactory network

scientific article published on 03 February 2014

AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers

scientific article published on 26 April 2011

Absence of mutations in the AKT1 oncogene in glioblastomas and medulloblastomas.

scientific article

Activation of phosphatidylinositol 3-kinase by cellular prion protein and its role in cell survival

scientific article published in June 2005

Ambient Glutamate Promotes Paroxysmal Hyperactivity in Cortical Pyramidal Neurons at Amyloid Plaques via Presynaptic mGluR1 Receptors

scientific article published on 6 September 2016

Amyloid plaque formation precedes dendritic spine loss ⬇️

scientific article published on September 21, 2012

Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content

scientific article published in August 2007

Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis

scientific article published on 29 August 2016

An 8-Year-Old Girl with Posterior Fossa Mass

scientific article published on 01 May 2020

An assay to image neuronal microtubule dynamics in mice

scientific article

Analysis of 18F-FET PET for grading of recurrent gliomas: is evaluation of uptake kinetics superior to standard methods?

scientific article published in March 2006

Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities

scientific article

ApoE attenuates unresolvable inflammation by complex formation with activated C1q

scientific article published on 28 January 2019

Arc illuminates Alzheimer's pathophysiology

scientific article published in October 2012

Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy

scientific article published on 01 November 2020

Asymmetry of fibrillar plaque burden in amyloid mouse models

scientific article published on 15 May 2020

Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice

scientific article published on 29 February 2016

BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines

scientific article published on 26 July 2018

BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology

scientific article published on 11 January 2018

Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms.

scientific article published on June 2010

Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6.

scientific article published on 26 December 2016

Bevacizumab Has Differential and Dose-Dependent Effects on Glioma Blood Vessels and Tumor Cells ⬇️

scientific article published on July 25, 2011

Bevacizumab reduces toxicity of reirradiation in recurrent high-grade glioma

scientific article published on 25 June 2019

Bis(arylvinyl)pyrazines, -pyrimidines, and -pyridazines as imaging agents for tau fibrils and β-amyloid plaques in Alzheimer's disease models

scientific article published on 31 August 2012

Calcium dysregulation in Alzheimer's disease

scientific article published on 05 October 2007

Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein

scientific journal article

Cellular prion protein function in copper homeostasis and redox signalling at the synapse

scientific article

Cellular prion protein modulates the intracellular calcium response to hydrogen peroxide

scientific article

Chip-on-the-tip compact flexible endoscopic epifluorescence video-microscope for in-vivo imaging in medicine and biomedical research

scientific article

Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology.

scientific article

Consequences of Pharmacological BACE Inhibition on Synaptic Structure and Function

scientific article published on 23 June 2018

Contribution of the astrocytic tau pathology to synapse loss in progressive supranuclear palsy and corticobasal degeneration

scientific article published on 22 October 2020

Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members

scientific journal article

Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [18F]GE180 PET quantification

scientific article

Cross-sectional comparison of small animal [18F]-florbetaben amyloid-PET between transgenic AD mouse models

scientific article

Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium.

scientific article published on 5 May 2018

Dendritic Spine Pathology in Neurodegenerative Diseases

scientific article published on 22 February 2016

Dendritic pathology in prion disease starts at the synaptic spine.

scientific article

Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's disease

scientific article (publication date: 2013)

Dual PET Imaging of an H3K27M-Mutant Glioma With 18F-GE-180 and 18F-FET PET

scientific article published on 16 October 2020

Dynamic 18F-FET PET in suspected WHO grade II gliomas defines distinct biological subgroups with different clinical courses.

scientific article

Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice

scientific article published on 27 September 2018

Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy

scientific article published on 26 August 2019

Early-phase [18F]PI-2620 tau-PET imaging as a surrogate marker of neuronal injury

scientific article published on 21 April 2020

Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional Aβ deposition rate and plaque burden at treatment initiation

scientific article published on 09 September 2018

Evidence of presynaptic location and function of the prion protein

scientific article (publication date: 15 October 1999)

Excitatory synaptic transmission is depressed in cultured hippocampal neurons of APP/PS1 mice

scientific article published on 20 February 2008

Expression of matrix metalloproteinases and their inhibitors in medulloblastomas and their prognostic relevance.

scientific article published in July 2004

Extent and prognostic value of MGMT promotor methylation in glioma WHO grade II

scientific article published on 12 November 2020

FET PET for the evaluation of untreated gliomas: correlation of FET uptake and uptake kinetics with tumour grading

scientific article published in September 2007

FRET-based calcium imaging: a tool for high-throughput/content phenotypic drug screening in Alzheimer disease

scientific article

Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

scientific article published on 08 June 2020

Fibrillar amyloid plaque formation precedes microglial activation

scientific article (publication date: 2015)

Fluorescent rhodanine-3-acetic acids visualize neurofibrillary tangles in Alzheimer's disease brains.

scientific article published on 27 June 2013

Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway.

scientific article published in August 2009

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

scientific article published on 09 February 2019

Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study

scientific article

HGG-15. MAPK PATHWAY ACTIVATION IN K27M MUTATED GLIOMAS – ASSOCIATION WITH CLINICAL PARAMETERS AND SURVIVAL.

scientific article published on 31 May 2017

High plasticity of axonal pathology in Alzheimer's disease mouse models.

scientific article published on 07 February 2017

Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation

scientific article published on 10 August 2020

Identification of Distant Metastases From Recurrent Gliosarcoma Using Whole-Body 18F-FDG PET/CT

scientific article published on 01 November 2019

Imaging glioma cell invasion in vivo reveals mechanisms of dissemination and peritumoral angiogenesis

scientific article

Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer's disease mouse model

scientific article

Impact of partial volume effect correction on cerebral β-amyloid imaging in APP-Swe mice using [(18)F]-florbetaben PET.

scientific article published on 20 September 2013

Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice

scientific article published on 17 December 2013

Improved risk stratification in younger <i>IDH</i> wild-type glioblastoma patients by combining a 4-miRNA signature with <i>MGMT</i> promoter methylation status

scientific article published on 01 January 2020

In Vivo Assessment of Neuroinflammation in 4-Repeat Tauopathies

scientific article published on 27 November 2020

In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria

scientific article published on 22 January 2019

In vivo imaging of retinal neurodegeneration at the single cell level in humans

scientific article published in June 2017

In vivo imaging reveals reduced activity of neuronal circuits in a mouse tauopathy model

scientific article published on 01 April 2019

In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques.

scientific article

In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks

scientific article

Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis

scientific article

Intraneuronal APP and extracellular Aβ independently cause dendritic spine pathology in transgenic mouse models of Alzheimer's disease

scientific article published on 11 April 2015

Involvement of GluN2B subunit containing N-methyl-d-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (Aβ) in murine models of Alzheimer's disease (AD).

scientific article published on 4 February 2017

Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease ⬇️

scientific article published on 05 February 2013

Label-free 3D-CLEM Using Endogenous Tissue Landmarks

scientific article published on 20 July 2018

Lack of Pur-alpha alters postnatal brain development and causes megalencephaly

scientific article published on 18 October 2011

Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau

scientific article published on 01 August 2019

Long-sustaining response in a patient with non-resectable, distant recurrence of glioblastoma multiforme treated by interstitial photodynamic therapy using 5-ALA: case report

scientific article

Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice

scientific article

Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second-Generation Amyloid-β Mouse Model

scientific article published on 13 July 2019

Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning

scientific article published on 13 July 2020

Longitudinal assessment of cerebral β-amyloid deposition in mice overexpressing Swedish mutant β-amyloid precursor protein using 18F-florbetaben PET.

scientific article published on 31 May 2013

Loss of HCN1 enhances disease progression in mouse models of CNG channel-linked retinitis pigmentosa and achromatopsia

scientific article published on 5 January 2016

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE

scientific article published on 07 January 2019

Loss of fragile X mental retardation protein precedes Lewy pathology in Parkinson's disease

scientific article published on 25 November 2019

Loss of the cellular prion protein affects the Ca2+ homeostasis in hippocampal CA1 neurons

scientific article published in September 2006

Methods for studying synaptosomal copper release

scientific article published in September 2003

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

scientific article

Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study

Modulation of L‐type voltage‐gated calcium channels by recombinant prion protein ⬇️

scientific article published on November 1, 2003

Molecular stereotactic biopsy technique improves diagnostic accuracy and enables personalized treatment strategies in glioma patients

scientific article published on 3 May 2014

Mouse brain synaptosomes accumulate copper-67 efficiently by two distinct processes independent of cellular prion protein

scientific article

Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice

scientific article

Mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons

scientific article published on 6 November 2006

Neurogenesis from Sox2 expressing cells in the adult cerebellar cortex

scientific article published on 21 July 2017

Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer's disease

scientific article

Non-invasive prediction of IDH-wildtype genotype in gliomas using dynamic 18F-FET PET

scientific article published on 13 August 2019

Optical needle endoscope for safe and precise stereotactically guided biopsy sampling in neurosurgery ⬇️

scientific article published on November 19, 2012

Pathological α-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb

scientific article

Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions

scientific article

Positron emission tomography with O-(2-[18F]fluoroethyl)-l-tyrosine versus magnetic resonance imaging in the diagnosis of recurrent gliomas

scientific article

Prion protein induced signaling cascades in monocytes

scientific article published on 6 December 2005

Proper cerebellar development requires expression of β1-integrin in Bergmann glia, but not in granule neurons

scientific article published on 28 February 2012

Publisher Correction: ApoE attenuates unresolvable inflammation by complex formation with activated C1q

scientific article published on 01 March 2019

Real-time imaging reveals the single steps of brain metastasis formation

scientific article

Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase.

scientific article published on February 2011

Role of APP for dendritic spine formation and stability ⬇️

scientific article published on November 18, 2011

Role of copper and manganese in prion disease progression

scientific article published on 25 July 2009

Role of presenilin1 in structural plasticity of cortical dendritic spines in vivo ⬇️

scientific article published on October 24, 2011

Seeding and transgenic overexpression of alpha-synuclein triggers dendritic spine pathology in the neocortex

scientific article

Small-Animal PET Imaging of Tau Pathology with 18F-THK5117 in 2 Transgenic Mouse Models

scientific article

Structural dynamics of dendritic spines are influenced by an environmental enrichment: an in vivo imaging study

scientific article

Synapse Formation and Function Is Modulated by the Amyloid Precursor Protein

scientific article

Tau deletion reduces plaque-associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease

scientific article published on 07 November 2019

Tcf4 regulates dendritic spine density and morphology in the adult brain.

scientific article

The NMDA receptor antagonist Radiprodil reverses the synaptotoxic effects of different amyloid-beta (Aβ) species on long-term potentiation (LTP)

scientific article published on 11 August 2018

The Role of APP in Structural Spine Plasticity

scientific article published on 10 May 2017

The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans

scholarly article by Xianyuan Xiang published in September 2018

The USP8 mutational status may predict long-term remission in patients with Cushing's disease

scientific article published on 29 June 2018

The neuropathology of fatal encephalomyelitis in human Borna virus infection

scientific article published on 26 July 2019

The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice.

scientific article

Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study

scientific article

Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice

scientific article published on 19 March 2019

Zoonotic spillover infections with Borna disease virus 1 leading to fatal human encephalitis, 1999-2019: an epidemiological investigation

scientific article published on 07 January 2020

hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations

scientific article published on 5 February 2013

η-Secretase processing of APP inhibits neuronal activity in the hippocampus

scientific article published on 31 August 2015

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