Search filters

List of works by Rachel E Piddock

Activity of Bruton's tyrosine-kinase inhibitor ibrutinib in patients with CD117-positive acute myeloid leukaemia: a mechanistic study using patient-derived blast cells

scientific article

Acute myeloid leukemia induces pro-tumoral p16INK4a driven senescence in the bone marrow microenvironment

scientific article published on 06 November 2018

CD38-Driven Mitochondrial Trafficking Promotes Bioenergetic Plasticity in Multiple Myeloma

scientific article published on 08 January 2019

HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia

scientific article published on 28 February 2018

Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment.

scientific article

Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC.

scientific article

NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts.

scientific article

PGC-1α driven mitochondrial biogenesis in stromal cells underpins mitochondrial trafficking to leukemic blasts

scientific article published on 20 July 2018

PI3Kδ and PI3Kγ isoforms have distinct functions in regulating pro-tumoural signalling in the multiple myeloma microenvironment

scientific article published on 10 March 2017

Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection.

scientific article published on 11 May 2016

The Role of PI3K Isoforms in Regulating Bone Marrow Microenvironment Signaling Focusing on Acute Myeloid Leukemia and Multiple Myeloma.

scientific article

Paulina is supported by:

About Paulina

Help