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List of works by Geoffrey Neale

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Germline genomic variants associated with childhood acute lymphoblastic leukemia

scientific journal article
Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia

scientific journal article
Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse

scientific article
Molecular characterization of the pediatric preclinical testing panel

scientific article
Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer.

scientific article published on 30 March 2011
Initial testing (stage 1) of AZD6244 (ARRY-142886) by the Pediatric Preclinical Testing Program.

scientific article
mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis.

scientific article
Initial testing (stage 1) of the cyclin dependent kinase inhibitor SCH 727965 (dinaciclib) by the pediatric preclinical testing program.

scientific article
Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.

scientific article published on 19 December 2018
Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer

scientific article
Genetic and clinical factors associated with obesity among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort

scientific article
Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection.

scientific article published on 22 August 2016
Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells

scientific article published on 01 July 2018
Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.

scientific article published on 7 August 2017
IRF1 Is a Transcriptional Regulator of ZBP1 Promoting NLRP3 Inflammasome Activation and Cell Death during Influenza Virus Infection

scientific article published on 10 January 2018
SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents

scientific article published on 19 August 2021
MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat

scientific article published on 09 August 2019
Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

scientific article
PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.

scientific article published on 13 November 2017
Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs

scientific article published on 21 February 2020
Will Attention by Vaccine Developers to the Host's Nuclear Hormone Levels and Immunocompetence Improve Vaccine Success?

article
Evaluation of a two-step iterative resampling procedure for internal validation of genome-wide association studies

scientific article published on 17 September 2015
XAF1 as a modifier of p53 function and cancer susceptibility

scientific article published on 24 June 2020
Homeostasis and transitional activation of regulatory T cells require c-Myc

scientific article published on 01 January 2020
Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer

scientific article published on 10 July 2020
Epigenetic Age Acceleration and Chronic Health Conditions among Adult Survivors of Childhood Cancer

scientific article published on 24 September 2020
Diagnostic utility of DNA methylation analysis in genetically unsolved pediatric epilepsies and CHD2 episignature refinement

Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor

scientific article published on 20 December 2019
Diagnostic Utility of Genome-wide DNA Methylation Analysis in Genetically Unsolved Developmental and Epileptic Encephalopathies and Refinement of a CHD2 Episignature

Evaluation of two-step iterative resampling procedure for internal validation of genome-wide association studies

scientific article published on 29 September 2014
Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion

scientific article published on 09 March 2020
Cohort Profile: The St. Jude Lifetime Cohort Study (SJLIFE) for paediatric cancer survivors

scientific article published on 29 December 2020
Germline Elongator mutations in Sonic Hedgehog medulloblastoma

scientific article published on 01 April 2020

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