List of works by Michelle M Le Beau

A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M

scientific article

A Morphologic and Cytochemical Study of Acute Myelomonocytic Leukemia with Abnormal Marrow Eosinophils Associated with Inv(16)(p13q22)

scientific article published on 01 June 1984

A complex genetic rearrangement in a t(10;14)(q24;q11) associated with T-cell acute lymphoblastic leukemia

scientific article published on January 1, 1992

A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q13 amplification

scientific article

A consistent pattern ofRIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q13 amplification

scientific article published in June 2000

A critical role for Apc in hematopoietic stem and progenitor cell survival

scientific journal article

A group of type I keratin genes on human chromosome 17: characterization and expression

scientific article

A human Hox 1 homeobox gene exhibits myeloid-specific expression of alternative transcripts in human hematopoietic cells

scientific article published on June 25, 1991

A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy

scientific article published on 29 December 2006

A long-range restriction map of the interleukin-4 and interleukin-5 linkage group on chromosome 5

scientific article published on 01 January 1990

A method for the rapid sequence-independent amplification of microdissected chromosomal material

scientific article published on August 1, 1992

A microarray study of altered gene expression after cytarabine resistance in acute myeloid leukemia

article

A model of APL with FLT3 mutation is responsive to retinoic acid and a receptor tyrosine kinase inhibitor, SU11657.

scientific article

A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.

scientific article published on 17 June 2013

A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes

scientific article

A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia

scientific article published on 01 February 2020

A physical and genetic linkage map of the distal long arm of human chromosome 5

scientific article published on 01 January 1992

A recurring chromosome rearrangement, dic(16;22), in acute nonlymphocytic leukemia

scientific article published on October 1988

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin

scientific article published on September 1, 1990

A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene

scientific article

ACUTE MYELOID LEUKAEMIA FOLLOWING INTERFERON-ALFA TREATMENT OF HAIRY CELL LEUKAEMIA

scientific article published on 01 March 1993

Abnormalities of chromosome band 11q23 and the MLL gene in pediatric myelomonocytic and monoblastic leukemias. Identification of the t(9;11) as an indicator of long survival

scientific article published on 01 November 1995

Acquired FANCA dysfunction and cytogenetic instability in adult acute myelogenous leukemia.

scientific article published on 13 March 2003

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

scientific article (publication date: September 2002)

Activation of Wnt/β-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cells

scientific article

Acute leukemia and related entities. Impact of new technology

scientific article published on 01 April 1991

Acute leukemia occurring after radiotherapy and chemotherapy with a nitrosourea, PCNU

scientific article published on 01 June 1988

Acute lymphoblastic leukemia in a patient with longstanding polycythemia vera: cytogenetic analysis reveals two distinct abnormal clones

scientific article published on 01 September 1988

Acute megakaryoblastic leukemia in Down's syndrome: report of a case and review of cytogenetic findings

scientific article published on January 1985

Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

scientific article

Acute myelomonocytic leukemia with abnormal eosinophils and inv(16) or t(16;16) has a favorable prognosis

scientific article published on 01 December 1986

Acute nonlymphocytic leukemia following etoposide and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung

scientific article published on 01 November 1987

Advances in high resolution SIMS studies of BrdU-labelled human metaphase chromosomes

scientific article published on 01 May 1996

Alternative splicing of human inwardly rectifying K+ channel ROMK1 mRNA

scientific article

Alternatively spliced ltk mRNA in neurons predicts a receptor with a larger putative extracellular domain

scientific article

Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer

scientific article

An (8;14)(q24;q11) translocation involving the T-cell receptor alpha-chain gene and the MYC oncogene 3' region in a B-cell lymphoma

scientific article published on 01 September 1989

An FHIT tumor suppressor gene?

scientific article published on April 1998

An anonymous DNA segment pTP5E (D5S70) maps to the long arm of chromosome 5 and identifies a Taq I polymorphism

scientific article published on March 1988

An integrated genomic approach to the assessment and treatment of acute myeloid leukemia.

scientific article published on April 2011

Analysis of deletions of the long arm of chromosome 11 in hematologic malignancies with fluorescence in situ hybridization

scientific article published on December 1993

Analysis of the t(6;11)(q27;q23) in leukemia shows a consistent breakpoint in AF6 in three patients and in the ML-2 cell line

scientific article

Anergic T lymphocytes selectively express an integrin regulatory protein of the cytohesin family

scientific journal article

Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders

scientific article

Assignment of SLC6A9 to human chromosome band 1p33 by in situ hybridization

scientific article published on January 1, 1995

Assignment of the GM-CSF, CSF-1, and FMS genes to human chromosome 5 provides evidence for linkage of a family of genes regulating hematopoiesis and for their involvement in the deletion (5q) in myeloid disorders

scientific article published on 01 January 1986

Assignment of the Gene Encoding the Human Apolipoprotein B mRNA Editing Enzyme (APOBEC1) to Chromosome 12p13.1

scientific article published on November 15, 1994

Assignment of the gastric inhibitory polypeptide receptor gene (GIPR) to chromosome bands 19q13.2-q13.3 by fluorescence in situ hybridization

scientific article

Assignment of the gene encoding glycogen synthase (GYS) to human chromosome 19, band q13.3.

scientific article published on 01 February 1993

Assignment of the gene encoding the alpha 1 subunit of the neuroendocrine/brain-type calcium channel (CACNL1A2) to human chromosome 3, band p14.3

scientific article published on August 1, 1992

Assignment of the human ubiquitous receptor gene (UNR) to 19q13.3 using fluorescence in situ hybridization

scientific article

Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia

scientific article published on 01 November 1987

Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. A unique cytogenetic-clinicopathological association

scientific article published on 01 September 1983

Association of red cell spherocytosis with deletion of the short arm of chromosome 8

scientific article published on 01 January 1987

Associations between morphology, karyotype, and clinical features in myeloid leukemias.

scientific article

Author Correction: RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia.

scientific article

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

scientific article published in Nature

BMP meets AML: induction of BMP signaling by a novel fusion gene promotes pediatric acute leukemia

scientific article

Bad-deficient mice develop diffuse large B cell lymphoma

scientific article

Balanced translocations involving chromosome bands 11q23 and 21q22 in therapy-related leukemia

scientific article published on 01 April 1992

Beta-cell transcription factors and diabetes: mutations in the coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not associated with maturity-onset diabetes of the young in Japanese

scientific article

Blast-1 possesses a glycosyl-phosphatidylinositol (GPI) membrane anchor, is related to LFA-3 and OX-45, and maps to chromosome 1q21-23

scientific article

Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia

scientific article

Bone marrow transplantation across major histocompatibility barriers in rabbits. I. A positive role for graft-versus-host reactivity in engraftment

scientific article published on 01 January 1990

Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice

scientific article

CBFA2(AML1) translocations with novel partner chromosomes in myeloid leukemias: association with prior therapy

scientific article published on 01 October 1998

CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia

scientific article published on 3 December 2012

Cancer biology: Heritable fragile sites in cancer

scientific article published in Nature

Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins

scientific article

Cancer predisposition and hematopoietic failure in Rad50(S/S) mice

scientific article published on September 2002

Cancer: hay in a haystack

scientific article

Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies

scientific article published in October 2001

Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia

scientific article published on 01 January 2006

Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc.

scientific article

Cellular myosin heavy chain in human leukocytes: isolation of 5' cDNA clones, characterization of the protein, chromosomal localization, and upregulation during myeloid differentiation

scientific article

Certain HLA antigens are associated with specific morphologic and cytogenetic subsets of acute myeloid leukemia.

scientific article published in March 1995

Characterization of a CD34+ cell line established from a child with large cell cutaneous lymphoma

scientific article published on August 1, 1993

Characterization of a novel myeloma cell line, MM.1.

scientific article published on March 1989

Characterization of donor-derived lymphocytes in chimeric rabbits

scientific article published on 01 June 1983

Characterization of the human pleiotrophin gene. Promoter region and chromosomal localization

scientific article (publication date: 25 December 1992)

Characterization of translocations in human cancer

scientific article published on 01 January 2003

Characterization of two 11q23.3–11q24 deletions and mapping of associated anonymous DNA markers

scientific article published on June 1, 1993

Characterization of yeast artificial chromosomes containing interleukin genes on human chromosome 5

scientific article published on January 1, 1992

Chromosomal abnormalities and molecular genetics of non-Hodgkin's lymphoma

scientific article published on 01 August 1998

Chromosomal abnormalities in Hodgkin's disease

scientific article

Chromosomal abnormalities in hematologic malignant diseases

scientific article published on January 1990

Chromosomal abnormalities in leukemia and lymphoma: clinical and biological significance

scientific article published on January 1986

Chromosomal abnormalities in myeloid hematologic malignancies

scientific article published on January 1989

Chromosomal abnormalities in non-Hodgkin's lymphomas

scientific article published on February 1990

Chromosomal assignment and tissue distribution of novel expressed sequence tags from a human pancreatic islet cDNA library

scientific article published on September 1995

Chromosomal fragile sites and cancer-specific breakpoints--a moderating viewpoint

scientific article published on 01 March 1988

Chromosomal fragile sites and cancer-specific rearrangements

scientific article published on April 1986

Chromosomal instability in chromosome band 12p13: multiple breaks leading to complex rearrangements including cytogenetically undetectable sub-clones.

scientific article

Chromosomal localization and characterization of c-abl in the t(6;9) of acute nonlymphocytic leukemia

scientific article published on December 1985

Chromosomal localization of the gene encoding GTPase-activating protein (RASA) to human chromosome 5, bands q13-q15.

scientific article published on February 1990

Chromosomal localization of the genes encoding the p50/p105 subunits of NF-kappa B (NFKB2) and the I kappa B/MAD-3 (NFKBI) inhibitor of NF-kappa B to 4q24 and 14q13, respectively

scientific article published on 01 October 1992

Chromosomal localization of the human AHR locus encoding the structural gene for the Ah receptor to 7p21-->p15.

scientific article published in January 1994

Chromosomal localization of the human G-CSF gene to 17q11 proximal to the breakpoint of the t(15;17) in acute promyelocytic leukemia

scientific article

Chromosomal localization of the human T cell receptor beta-chain genes

scientific article published on 01 May 1985

Chromosomal localization of the human hexabrachion (tenascin) gene and evidence for recent reduplication within the gene

scientific article published on April 1, 1990

Chromosomal location and some structural features of human clathrin light-chain genes (CLTA and CLTB)

scientific article

Chromosomal loss and deletion are the most common mechanisms for loss of heterozygosity from chromosomes 5 and 7 in malignant myeloid disorders

scientific article published on March 15, 1992

Chromosomal sensitivity of lymphocytes from individuals with therapy-related acute nonlymphocytic leukemia

scientific article published on 01 April 1989

Chromosomal sublocalization of the human p97 melanoma antigen

scientific article

Chromosome 18 breakpoint in t(11;18)(q21;q21) translocation associated with MALT lymphoma is proximal to BCL2 and distal to DCC

scientific article published on 01 February 1999

Chromosome abnormalities in advanced stage lymphoblastic lymphoma of children and adolescents: a report from CCG-E08.

scientific article published on January 2007

Chromosome abnormalities may correlate with prognosis in Burkitt/Burkitt-like lymphomas of children and adolescents: a report from Children's Cancer Group Study CCG-E08.

scientific article published on March 2004

Circulating immune complexes correlate with remission duration in acute myeloid leukemia

scientific article published on 01 February 1991

Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7

scientific article

Clinical and cytogenetic responses to granulocyte-macrophage colony-stimulating factor in therapy-related myelodysplasia

scientific article published on November 15, 1992

Clinical and prognostic significance of chromosomal abnormalities in childhood acute myeloid leukemia de novo

scientific article published on 01 January 1995

Clinical, morphologic, and cytogenetic characteristics of 26 patients with acute erythroblastic leukemia

scientific article published on 01 December 1992

Clinical, morphologic, and cytogenetic characteristics of patients with lymphoid malignancies characterized by both t(14;18)(q32;q21) and t(8;14)(q24;q32) or t(8;22)(q24;q11)

scientific article published on 01 July 1990

Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series.

scientific article

Clinicopathologic manifestations and breakpoints of the t(3;5) in patients with acute nonlymphocytic leukemia

scientific article published on January 1989

Clonal architecture in patients with myelodysplastic syndromes and double or minor complex abnormalities: Detailed analysis of clonal composition, involved abnormalities, and prognostic significance

scientific article published on 24 September 2018

Cloning and characterization of MST4, a novel Ste20-like kinase

scientific article

Cloning of cDNAs for human phosphoribosylpyrophosphate synthetases 1 and 2 and X chromosome localization of PRPS1 and PRPS2 genes

scientific article published on November 1990

Cloning, tissue expression, and chromosomal localization of SUR2, the putative drug-binding subunit of cardiac, skeletal muscle, and vascular KATP channels

scientific article

Coexistent double gammopathy, myeloproliferative disorder, and malignant lymphoma

scientific article published on 01 January 1990

Common fragile sites are characterized by histone hypoacetylation

scientific article published on 28 August 2009

Comparison of eosinophils in acute nonlymphocytic leukaemia associated with the t(8;21) and inv(16)

scientific article published on 01 January 1985

Comparison of the human and mouse genes encoding the telomeric protein, TRF1: chromosomal localization, expression and conserved protein domains

scientific article

Complex secondary chromosome abnormalities in advanced stage anaplastic large cell lymphoma of children and adolescents: a report from CCG-E08.

scientific article published on December 2006

Constitutional t(15;17): clarification of the chromosomal breakpoints

scientific article

Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21

scientific article published on July 3, 1995

Cooperation of Cytokine Signaling with Chimeric Transcription Factors in Leukemogenesis: PML-Retinoic Acid Receptor Alpha Blocks Growth Factor-Mediated Differentiation

Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation.

scientific article

Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis

scientific article published on 30 March 2015

Cytogenetic abnormalities in a secondary lymphoma complicating cardiac transplantation

scientific article published on 01 April 1989

Cytogenetic abnormalities in childhood acute lymphoblastic leukemia

scientific article published on January 1991

Cytogenetic analysis of 51 patients with chronic myeloid leukemia

scientific article published in October 1990

Cytogenetic and genetic pathways in therapy-related acute myeloid leukemia.

scientific article

Cytogenetic and molecular analysis of the deletions of chromosome 5 in myeloid disorders.

scientific article

Cytogenetic and molecular analysis of therapy-related leukemia

scientific article

Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases.

scientific article

Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases

scientific article

Cytogenetic and molecular detection of genetic mutations in human tumours

scientific article

Cytogenetic characterization of B-cell lymphomas from severe combined immunodeficiency disease mice given injections of lymphocytes from Epstein-Barr virus-positive donors

scientific article published on September 1, 1992

Cytogenetic clonality in myelodysplastic syndromes studied with fluorescence in situ hybridization: lineage, response to growth factor therapy, and clone expansion

scientific article published on 01 March 1993

Cytopenia levels for aiding establishment of the diagnosis of myelodysplastic syndromes

scientific article published on 17 August 2016

Cytotoxic Therapy-Induced Effects on Both Hematopoietic and Marrow Stromal Cells Promotes Therapy-Related Myeloid Neoplasms

scientific article published on 01 July 2020

DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia

scientific article

DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.

scientific article

Deletions of Interferon Genes in Acute Lymphoblastic Leukemia

article

Deletions of chromosome 5 in malignant myeloid disorders.

scientific article published on January 1992

Der(16)T(1-16) is a nonrandom secondary chromosome aberration in many types of human neoplasia, including myxoid liposarcoma, rhabdomyosarcoma and Philadelphia-chromosome-positive acute lymphoblastic-leukemia

scientific article published on March 1995

Detecting genetic changes in human tumor cells: have scientists "gone fishing?"

scientific article published on 01 April 1993

Detection of 11q23/MLL rearrangements in infant leukemias with fluorescence in situ hybridization and molecular analysis.

scientific article published on August 1995

Detection of 9p deletions in leukemia cell lines by interphase fluorescence in situ hybridization with YAC-derived probes

scientific article published on 01 August 1995

Detection of DNA rearrangements in the AML1 and ETO loci and of an AML1/ETO fusion mRNA in patients with t(8;21) acute myeloid leukemia

scientific article published on February 1993

Detection of numerical chromosomal abnormalities in neoplastic hematopoietic cells by in situ hybridization with a chromosome-specific probe

scientific article published on January 1990

Detection of translocations affecting the BCL6 locus in B cell non-Hodgkin's lymphoma by interphase fluorescence in situ hybridization

scientific article published on 01 September 2001

Detection of trisomy 12 in chronic lymphocytic leukemia by fluorescence in situ hybridization to interphase cells: a simple and sensitive method

scientific article published on 01 April 1992

Development of dysmyelopoietic syndrome in a hairy cell leukemia patient treated with chlorambucil: cytogenetic and morphologic evaluation

scientific article published on 01 February 1983

Diagnostic evaluation of RNA sequencing for the detection of genetic abnormalities associated with Ph-like acute lymphoblastic leukemia (ALL).

scientific article published on 17 November 2016

Differing clinical features between Japanese and Caucasian patients with myelodysplastic syndromes: Analysis from the International Working Group for Prognosis of MDS

scientific article published on 06 September 2018

Direct cloning of DNA sequences from the common fragile site region at chromosome band 3p14.2.

scientific article published in July 1996

Direct correlation of cytogenetic findings with cell morphology using in situ hybridization: an analysis of suspicious cells in bone marrow specimens of two patients completing therapy for acute lymphoblastic leukemia

scientific article published on 01 June 1991

Dissecting the role of aberrant DNA methylation in human leukaemia

scientific article published on 22 May 2015

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.

scholarly article

Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis

scientific article published on 11 January 2013

Do terminal deletions of 11q23 exist? Identification of undetected translocations with fluorescence in situ hybridization

scientific article published on 01 August 1993

Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation

scientific article published on 3 June 2013

EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors

scientific article

ERK8, a new member of the mitogen-activated protein kinase family

scientific article

Enhanced expression of FHL2 leads to abnormal myelopoiesis in vivo

scientific article published on 16 April 2009

Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles.

scientific article published on 8 June 2016

Establishment and characterization of a megakaryoblast cell line with amplification of MLL.

scientific article published on July 1998

Establishment and characterization of a neuroendocrine skin carcinoma cell line.

scientific article published in March 1987

Establishment of a leukemia cell line with i(12p) from a patient with a mediastinal germ cell tumor and acute lymphoblastic leukemia

scientific article published on September 1994

Establishment of cell lines from B-cell precursor acute lymphoblastic leukemia

scientific article published on November 1993

Evaluation of recurring cytogenetic abnormalities in the treatment of myelodysplastic syndromes

scientific article published on 11 December 2006

Evidence favoring lineage fidelity in acute nonlymphocytic leukemia: absence of immunoglobulin gene rearrangements in FAB types M4 and M5

scientific article published on 01 January 1987

Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders

scientific article

Evidence for two distinct c-src loci on human chromosomes 1 and 20

scientific article published on November 1, 1984

Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy

scientific article

Expression and cytogenetic localization of the human SM22 gene (TAGLN)

scientific article

Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.

scientific article

Expression, regulation, and chromosomal localization of the Max gene

scientific article published on April 1, 1992

Familial Lymphoproliferative Disorders with Chromosomal Fragile Site Analysis.

scientific article

Familial myeloid leukemia associated with loss of the long arm of chromosome 5

scientific article published on 01 April 1996

Fluorescence in situ hybridization in cancer diagnosis

scientific article

Fluorescence in situ hybridization mapping of translocations and deletions involving the short arm of human chromosome 12 in malignant hematologic diseases.

scientific article published on November 1994

Fluorescence in situ hybridization: a sensitive method for trisomy 8 detection in bone marrow specimens

scientific article published on 01 June 1992

Fluorescence in situ hybridization: uses and limitations

scientific article

Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia

scientific article published on February 2006

Frequency of del(12p) is commonly underestimated in myelodysplastic syndromes: Results from a German diagnostic study in comparison with an international control group

scientific article published on 10 September 2015

Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia

scientific article

Gene encoding the alpha chain of the T-cell receptor is moved immediately downstream of c-myc in a chromosomal 8;14 translocation in a cell line from a human T-cell leukemia

scientific article published on May 1986

Gene expression profiles in acute myeloid leukemia with common translocations using SAGE.

scientific article

Gene mapping by FISH

scientific article published on 01 January 1997

Genetic and physical mapping of the Treacher Collins syndrome locus: refinement of the localization to chromosome 5q32-33.2

scientific article (publication date: July 1992)

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

scientific article

Genetic mapping of the human polymeric immunoglobulin receptor gene to chromosome region 1q31----q41

scientific article

Genetic pathways leading to therapy-related myeloid neoplasms

scientific article

Genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibility

scientific article published on 18 March 2009

Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.

scientific article

Genomic organization and chromosomal localization of the gene TCF15 encoding the early mesodermal basic helix-loop-helix factor bHLH-EC2

scientific article

Genomic organization and chromosomal localization of the human and mouse genes encoding the alpha receptor component for ciliary neurotrophic factor

scientific article published on January 1995

Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1

scientific article published on July 1, 1990

Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor

scientific article published in January 2002

Graft-versus-host reactions and abrogation of allotype suppression following histoincompatible lymphoid cell transfers in rabbits

scientific article published on 01 June 1984

Growth disadvantage of 45,X and 46,X,del (X) (p11) fibroblasts

scientific article published on April 1, 1988

HEN1 and HEN2: a subgroup of basic helix-loop-helix genes that are coexpressed in a human neuroblastoma

scientific article

HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo

scientific article

Haploinsufficiency of Apc leads to ineffective hematopoiesis

scientific article

Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders

scientific article

Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice

scientific article published on 31 December 2013

Haploinsufficient loss of multiple 5q genes may fine-tune Wnt signaling in del(5q) therapy-related myeloid neoplasms.

scientific article published on 13 November 2015

Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis

scientific article

Hepsin, a cell membrane-associated protease. Characterization, tissue distribution, and gene localization

scientific article

Heterogeneity in the breakpoints in balanced rearrangements involving band 12p13 in hematologic malignancies identified by fluorescence in situ hybridization: TEL (ETV6 ) is involved in only one half

scientific article published on 01 December 1997

Heterogeneity of breakpoints of 11q23 rearrangements in hematologic malignancies identified with fluorescence in situ hybridization

scientific article published on 01 July 1993

High-throughput mapping of origins of replication in human cells

scientific article

Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome

scientific article

Homozygous deletion of the alpha- and beta 1-interferon genes in human leukemia and derived cell lines

scientific article

Hu-ets-2 is translocated to chromosome 8 in the t(8;21) in acute myelogenous leukemia

scientific article

Human CDC23: cDNA cloning, mapping to 5q31, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias

scientific article

Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): localization to chromosome 2 and identification of a simple tandem repeat polymorphism

scientific article

Human KRML (MAFB): cDNA cloning, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias

scientific article (publication date: August 1999)

Human Phosphoribosylpyrophosphate Synthetase (PRS) 2: An Independent Active, X Chromosone-Linked PRS Isoform

scientific article published on 01 January 1991

Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations

scientific article

Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency

scientific article

Human glucagon-like peptide-1 receptor gene. Localization to chromosome band 6p21 by fluorescence in situ hybridization and linkage of a highly polymorphic simple tandem repeat DNA polymorphism to other markers on chromosome 6

scientific article

Human glutamine: fructose-6-phosphate amidotransferase: characterization of mRNA and chromosomal assignment to 2p13

scientific article

Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity

scientific journal article

Human hexokinase II: localization of the polymorphic gene to chromosome 2.

scientific article

Human insulin receptor substrate-1 gene (IRS1): chromosomal localization to 2q35-q36.1 and identification of a simple tandem repeat DNA polymorphism

scientific article published on April 1993

Human mitochondrial enoyl-CoA hydratase gene (ECHS1): structural organization and assignment to chromosome 10q26.2-q26.3

scientific journal article

Human somatostatin receptor genes: localization of SSTR5 to human chromosome 20p11.2

scientific article (publication date: September 1993)

Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms

scientific article

Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical, and genetic map of chromosome 7.

scientific article

Human von Willebrand factor gene and pseudogene: structural analysis and differentiation by polymerase chain reaction

scientific article

Hypercalcemia and Lytic Bone Lesions in a Patient with B-Cell Non-Hodgkin's Lymphoma

scientific article published on January 26, 1984

Hyperdiploidy arising from near-haploidy in childhood acute lymphoblastic leukemia

scientific article published on 01 June 1992

Identification and analysis of the gene encoding human PC2, a prohormone convertase expressed in neuroendocrine tissues

scientific article published on June 1, 1992

Identification and characterization of the gene encoding a second proteolipid subunit of human vacuolar H(+)-ATPase (ATP6F)

scientific article

Identification and molecular characterization of CALM/AF10fusion products in T cell acute lymphoblastic leukemia and acute myeloid leukemia

scientific article

Identification of Nck family genes, chromosomal localization, expression, and signaling specificity

scientific article

Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study

scientific article published on 4 February 2013

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

scientific article published on December 1, 1991

Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells

scientific article

Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML.

scientific article

Identification of a novel metastasis-suppressor region on human chromosome 12

scientific article published on 01 August 1998

Identification of novel cryptic translocations involving IGH in B-cell non-Hodgkin's lymphomas

scientific article published on 01 October 2002

Identification of pericentric inversion 12, inv(12)(p13.1q11), by fluorescence in situ hybridization in a patient with acute myeloid leukemia (AML-M6)

scientific article published on 01 September 1997

Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas

scientific article

Identification of unstable sequences within the common fragile site at 3p14.2: implications for the mechanism of deletions within fragile histidine triad gene/common fragile site at 3p14.2 in tumors

scientific article published on June 2002

Imaging of BrdU-labeled human metaphase chromosomes with a high resolution scanning ion microprobe

scientific article published on 01 February 1997

Immunoglobulin gene rearrangements in acute lymphoblastic leukemia with the 9;11 translocation.

scientific article published in January 1991

Impact of chromosomal translocations on prognosis in childhood acute lymphoblastic leukemia

scientific article published in December 1991

Impact of disease burden at time of allogeneic stem cell transplantation in adults with acute myeloid leukemia and myelodysplastic syndromes

scientific article published on 01 May 2005

Impaired replication dynamics at the FRA3B common fragile site

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Implication of prior treatment with drug combinations including inhibitors of topoisomerase II in therapy-related monocytic leukemia with a 9;11 translocation

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Increased genetic instability of the common fragile site at 3p14 after integration of exogenous DNA.

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Increased numbers of marrow basophils may be associated with a t(6;9) in ANLL.

scientific article published in April 1985

Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia

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Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apcdel/+ MDS mouse model.

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Insertion (10;11)(p11;q23q24) in two cases of acute monocytic leukemia

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Interferon and c-ets-1 genes in the translocation (9;11)(p22;q23) in human acute monocytic leukemia

scientific article published on 01 January 1986

Interleukin-4 and interleukin-5 map to human chromosome 5 in a region encoding growth factors and receptors and are deleted in myeloid leukemias with a del(5q).

scientific article published in February 1989

International scoring system for evaluating prognosis in myelodysplastic syndromes

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Interphase cytogenetic analysis detects minimal residual disease in a case of acute lymphoblastic leukemia and resolves the question of origin of relapse after allogeneic bone marrow transplantation

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Interstitial deletion of chromosome 5, del(5q), in a newborn with Down syndrome and an unusual hematologic disorder

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Interstitial uniparental isodisomy at clustered breakpoint intervals is a frequent mechanism of NF1 inactivation in myeloid malignancies

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Inversion of chromosome 16 and uncommon rearrangements of the CBFB and MYH11 genes in therapy-related acute myeloid leukemia: rare events related to DNA-topoisomerase II inhibitors?

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Involvement of the AML1 gene in the t(3;21) in therapy-related leukemia and in chronic myeloid leukemia in blast crisis

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Isolation and analysis of candidate myeloid tumor suppressor genes from a commonly deleted segment of 7q22.

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Isolation and analysis of the 21q+ chromosome in the acute myelogenous leukemia 8;21 translocation: evidence that c-mos is not translocated

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Isolation and chromosomal localization of the human glutathione peroxidase gene.

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Isolation of a cDNA Clone Encoding a KATP Channel-Like Protein Expressed in Insulin-Secreting Cells, Localization of the Human Gene to Chromosome Band 21q22.1, and Linkage Studies With NIDDM

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Isolation of a cDNA clone encoding a KATP channel-like protein expressed in insulin-secreting cells, localization of the human gene to chromosome band 21q22.1, and linkage studies with NIDDM

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Isolation of a yeast artificial chromosome spanning the 8;21 translocation breakpoint t(8;21)(q22;q22.3) in acute myelogenous leukemia

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Isolation of the human peroxisomal acyl-CoA oxidase gene: organization, promoter analysis, and chromosomal localization

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Janet Davidson Rowley (1925-2013).

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KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer

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Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts

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Lineage involvement by BCR/ABL in Ph+ lymphoblastic leukemias: chronic myelogenous leukemia presenting in lymphoid blast vs Ph+ acute lymphoblastic leukemia.

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Linkage and linkage disequilibrium in chromosome band 1p36 in American Chaldeans with inflammatory bowel disease

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Localization of human somatostatin receptor 5 gene (SSTR5) to chromosome band 16p13.3 by fluorescence in situ hybridization

scientific article published on April 10, 1995

Localization of prostate cancer metastasis-suppressor activity on human chromosome 17

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Localization of the Chinese hamster MHC locus to chromosome 1q17-->q18 by fluorescence in situ hybridization.

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Localization of the Gene Encoding a Neutral Amino Acid Transporter-like Protein to Human Chromosome Band 19q13.3 and Characterization of a Simple Sequence Repeat DNA Polymorphism

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Localization of the Genes Encoding Two Transcription Factors, LMX1 and CDX3, Regulating Insulin Gene Expression to Human Chromosomes 1 and 13

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Localization of the gene encoding insulin-degrading enzyme to human chromosome 10, bands q23→q25

scientific article published on January 1, 1991

Localization of the gene encoding proteinase-3 (the Wegener's granulomatosis autoantigen) to human chromosome band 19p13.3.

scientific article published on 01 January 1993

Localization of the glucagon receptor gene to human chromosome band 17q25

scientific article (publication date: 15 March 1994)

Localization of the human urate oxidase gene (UOX) to 1p22

scientific article published on 01 January 1992

Localization of the kappa opioid receptor gene to human chromosome band 8q11.2.

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Localization of the oncogene c-erbA1 immediately proximal to the acute promyelocytic leukaemia breakpoint on chromosome 17

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Localization of the proto-oncogene MOS to 8q11-q12 by in situ chromosomal hybridization

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Long-range mapping of the Philadelphia chromosome by pulsed-field gel electrophoresis.

scientific article published in March 1988

Low incidence of TAL1 gene rearrangements in adult acute lymphoblastic leukemia: A cancer and leukemia group B study (8762)

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MDM2 SNP309 and TP53 Arg72Pro interact to alter therapy-related acute myeloid leukemia susceptibility

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MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia

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MLL5, a homolog of Drosophila trithorax located within a segment of chromosome band 7q22 implicated in myeloid leukemia

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Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity

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Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia

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Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia

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Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16)

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MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia

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MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia

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Modeling myeloid leukemia tumor suppressor gene inactivation in the mouse

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Molecular analysis of TCRB and ABL in a t(7;9)-containing cell line (SUP-T3) from a human T-cell leukemia

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Molecular analysis of a chromosomal translocation, t(9;14)(p13;q32), in a diffuse large-cell lymphoma cell line expressing the Ki-1 antigen

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Molecular analysis of a t(11;14)(q23;q11) from a patient with null‐cell acute lymphoblastic leukemia

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Molecular analysis of human complement component C5: localization of the structural gene to chromosome 9

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Molecular biology and experimental models for hematologic malignant diseases: workshop of the NIH Pathology B Study Section

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Molecular characterization of 16p deletions associated with inversion 16 defines the critical fusion for leukemogenesis.

scientific article published on February 1995

Molecular characterization of KLHL3, a human homologue of the Drosophila kelch gene

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Molecular characterization of a human DNA kinase

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Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins

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Molecular cloning of the breakpoint junction of a human chromosomal 8;14 translocation involving the T-cell receptor alpha-chain gene and sequences on the 3' side of MYC.

scientific article published on September 1986

Molecular cloning of the breakpoints of a complex Philadelphia chromosome translocation: identification of a repeated region on chromosome 17.

scientific article published on June 1992

Molecular cloning, expression, and chromosomal localization of the gene encoding a human myeloid membrane antigen (gp150)

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Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure

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Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1-1.5 Mb and preparation of a PAC-based physical map.

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Molecular genetics of myeloid leukemia: identification of the commonly deleted segment of chromosome 20

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Monosomal karyotype in MDS: explaining the poor prognosis?

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Morphology in Ki-1(CD30)-positive non-Hodgkin's lymphoma is correlated with clinical features and the presence of a unique chromosomal abnormality, t(2;5)(p23;q35)

scientific article published on 01 April 1990

Multiple unrelated clonal abnormalities in host bone marrow cells after allogeneic stem cell transplantation

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Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis

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Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

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Myelodysplasia and acute leukemia following high-dose chemotherapy and autologous bone marrow or peripheral blood stem cell transplantation

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Myelodysplastic syndromes

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Myeloid Leukemia After Cytotoxic Therapy and Other Hematotoxins

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Myeloid leukemia after hematotoxins

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Myeloid malignancies induced by alkylating agents in Nf1 mice

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New comprehensive cytogenetic scoring system for primary myelodysplastic syndromes (MDS) and oligoblastic acute myeloid leukemia after MDS derived from an international database merge

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Nineteen cases of the t(1;22)(p13;q13) acute megakaryblastic leukaemia of infants/children and a review of 39 cases: report from a t(1;22) study group

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Nonlymphoblastic T-cell lymphoma in children

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Oncogenic K-ras cooperates with PML-RAR alpha to induce an acute promyelocytic leukemia-like disease.

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One FISH, two FISH, red FISH, blue FISH.

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Overexpression and knockout of miR-126 both promote leukemogenesis

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PML-RARα co-operates with Sox4 in acute myeloid leukemia development in mice

scientific article published on 9 November 2012

Pancreatic Islet Expression Studies and Polymorphic DNA Markers in the Genes Encoding Hepatocyte Nuclear Factor-3α, -3β, -3γ, -4γ, and -6

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Pesticide exposures in children with non-Hodgkin lymphoma

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Physical and genetic map of 5q31: use of fluorescence in situ hybridization data to identify errors in the CEPH database. Centre d'Etude de Polymorphisme Humain

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Physical localization of 70 polymorphic markers to human chromosome 5 by fluorescence in situ hybridization

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Point mutation in essential genes with loss or mutation of the second allele: relevance to the retention of tumor-specific antigens

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Post-transplant lymphoproliferative disorder subtypes correlate with different recurring chromosomal abnormalities

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Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone

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Precise localization of theFHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affectFHIT transcription in tumor cell lines

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Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites

scientific article published on August 1, 1991

Prenatal detection of 46,XY,rec(5),dup q, inv(5)(p13q33) using DNA analysis, flow cytometry, and in situ hybridization to supplement classical cytogenetic analysis

scientific article published on 01 November 1988

Prevalence of the inactivating 609C-->T polymorphism in the NAD(P)H:quinone oxidoreductase (NQO1) gene in patients with primary and therapy-related myeloid leukemia.

scientific article published in July 1999

Prognosis and therapy when acute promyelocytic leukemia and other "good risk" acute myeloid leukemias occur as a therapy-related myeloid neoplasm.

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Prognostic implications of morphology and karyotype in primary myelodysplastic syndromes

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Prognostic significance of additional cytogenetic abnormalities in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia treated with interferon-alpha: a Cancer and Leukemia Group B study.

scientific article published in July 2004

Progress in Cancer Research, Prevention, and Care

scientific article published on 01 September 2020

Prospective karyotype analysis in adult acute lymphoblastic leukemia: the cancer and leukemia Group B experience

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Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer

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Protooncogene expression and the clinical characteristics of acute nonlymphocytic leukemia: A Leukemia Intergroup pilot study.

scientific article published in January 1989

Publisher Correction: miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia.

scientific article published on 10 April 2018

RAS, FLT3, and TP53 mutations in therapy-related myeloid malignancies with abnormalities of chromosomes 5 and 7.

scientific article published in March 2004

RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia.

scientific article published on 21 March 2018

Rearrangements of chromosome 3 involving bands 3q21 and 3q26 are associated with normal or elevated platelet counts in acute nonlymphocytic leukemia

Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II

scientific article published on 01 December 1993

Reassignment of pEFD70.3 (D18S23) to human chromosome band 21q22.2 (D21S412) by physical mapping

scientific article published on 01 March 1993

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia

scientific article published on April 10, 2003

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia.

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Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes.

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Refined mapping of genomic rearrangements involving the short arm of chromosome 9 in acute lymphoblastic leukemias and other hematologic malignancies

scientific article published on 01 September 1995

Refinement of the Smallest Commonly Deleted Segment of Chromosome 20 in Malignant Myeloid Diseases and Development of a PAC-Based Physical and Transcription Map

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Refinement of the commonly deleted segment in myeloid leukemias with a del(20q)

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Refractory cytopenia with multilineage dysplasia: further characterization of an 'unclassifiable' myelodysplastic syndrome.

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Regional localization of the human thrombomodulin gene to 20p12-cen

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Regulated Capture of Vκ Gene Topologically Associating Domains by Transcription Factories

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Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction

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Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

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Report of the chromosome 5 workshop

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Report of the committee on the genetic constitution of chromosome 18.

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Report of the committee on the genetic constitution of chromosomes 18 and 19.

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Report of the first international workshop on human chromosome 18 mapping

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Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms

scientific article published on 4 March 2016

Revised international prognostic scoring system for myelodysplastic syndromes

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Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization

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Sequence-independent amplification and labeling of yeast artificial chromosomes for fluorescence in situ hybridization

scientific article published on 01 January 1994

Short remission durations in therapy-related leukemia despite cytogenetic complete responses to high-dose cytarabine

scientific article published on 01 October 1988

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

scholarly article

Somatic cell hybrid mapping of human chromosome band 5q31: a region important to hematopoiesis

scientific article published on January 1, 1992

Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder

scientific journal article

Specific chromosomal abnormalities in acute nonlymphocytic leukemia correlate with drug susceptibility in vivo.

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Stage- and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells

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Structural organization and mapping of the human mitochondrial glycerol phosphate dehydrogenase-encoding gene and pseudogene

scientific article published in June 1996

Structure and chromosomal localization of the functional intronless human JUN protooncogene

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Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein

scientific article

Structure and chromosomal localization of the human gene for a brain form of prostaglandin D2 synthase

scientific article (publication date: 15 November 1992)

Structure of the gene encoding CD34, a human hematopoietic stem cell antigen

scientific article published on April 1, 1992

Structure of the gene for human plasminogen activator inhibitor-2. The nearest mammalian homologue of chicken ovalbumin

scientific article (publication date: 5 April 1989)

Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development

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Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis

scientific article published in November 2007

T-cell receptor alpha-chain gene is split in a human T-cell leukemia cell line with a t(11;14)(p15;q11).

scientific article published on December 1986

TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia

scientific article published on December 15, 1991

TEL and KIP1 define the smallest region of deletions on 12p13 in hematopoietic malignancies

scientific article published on August 15, 1995

TRF2 and lamin A/C interact to facilitate the functional organization of chromosome ends

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TTID: A novel gene at 5q31 encoding a protein with titin-like features

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The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

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The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

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The API2/MALT1 fusion product may lead to germinal center B cell lymphomas by suppression of apoptosis

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The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors

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The Dawn of the Molecular Era of the Myelodysplastic Syndromes

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The Harmful Consequences of Increased Fitness in Hematopoietic Stem Cells

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The LCK gene is involved in the t(1;7)(p34;q34) in the T-cell acute lymphoblastic leukemia derived cell line, HSB-2.

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The clathrin-binding domain of CALM-AF10 alters the phenotype of myeloid neoplasms in mice

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The cytogenetics of myelodysplastic syndromes

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The gene encoding decay-accelerating factor (DAF) is located in the complement-regulatory locus on the long arm of chromosome 1.

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The histone code and treatments for acute myeloid leukemia

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The human Evi-1 gene is located on chromosome 3q24-q28 but is not rearranged in three cases of acute nonlymphocytic leukemias containing t(3;5)(q25;q34) translocations

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The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26

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The human met oncogene is related to the tyrosine kinase oncogenes

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The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q

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The predictive value of initial cytogenetic studies in 148 adults with acute nonlymphocytic leukemia: A 12-year study (1970–1982)

scientific article published on 01 November 1983

The proportion of abnormal karyotypes in acute leukemia samples related to method of preparation

scientific article published on 01 March 1991

The relationship between secondary chromosomal abnormalities and blast transformation in chronic myelogenous leukemia

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The role of comprehensive cancer centers in survivorship care

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The role of late/slow replication of the FRA16D in common fragile site induction

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The role of the c-mos gene in the 8;21 translocation in human acute myeloblastic leukemia

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The spectrum of somatic mutations in high-risk acute myeloid leukaemia with -7/del(7q).

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The t(2;5)(p23;q35): a recurring chromosomal abnormality in Ki-1-positive anaplastic large cell lymphoma.

scientific article published on December 1989

Therapy-Related Myelodysplastic Syndrome

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Therapy-related myeloid leukaemia: A model for leukemogenesis in humans

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Therapy-related myeloid neoplasms: when genetics and environment collide

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Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12

scientific article published on January 1, 1991

Time-dependent changes in mortality and transformation risk in MDS.

scientific article published on 22 June 2016

Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q)

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Transforming growth factor type beta 3 maps to human chromosome 14, region q23-q24

scientific article published on 01 December 1988

Translocation (2;9)(p12;p23) in a case of acute leukemia with t(4;11)(q21;q23). Lack of rearrangement of the kappa and interferon gene loci

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Translocation and rearrangement of myeloperoxidase gene in acute promyelocytic leukemia

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Translocation of the p53 gene in t(15;17) in acute promyelocytic leukaemia

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Treatment of therapy-related myeloid neoplasms with high-dose cytarabine/mitoxantrone followed by hematopoietic stem cell transplant

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Trisomy 6: a recurring cytogenetic abnormality associated with marrow hypoplasia

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Trisomy 8 in human hematologic neoplasia and the c-myc and c-mos oncogenes

Tumor suppressor gene inactivation in myeloid malignancies

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Unexpected heterogeneity of BCR-ABL fusion mRNA detected by polymerase chain reaction in Philadelphia chromosome-positive acute lymphoblastic leukemia

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Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.

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Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies

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Validation of WHO classification-based Prognostic Scoring System (WPSS) for myelodysplastic syndromes and comparison with the revised International Prognostic Scoring System (IPSS-R). A study of the International Working Group for Prognosis in Myelo

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Validation of cytogenetic risk groups according to International Prognostic Scoring Systems by peripheral blood CD34+FISH: results from a German diagnostic study in comparison with an international control group

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Value of molecular monitoring during the treatment of chronic myeloid leukemia: a Cancer and Leukemia Group B study

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Variability of 11q23 rearrangements in hematopoietic cell lines identified with fluorescence in situ hybridization

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Variant translocations (9;11): identification of the critical genetic rearrangement

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axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

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c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations.

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c-src is consistently conserved in the chromosomal deletion (20q) observed in myeloid disorders

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cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins

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cDNA cloning, expression pattern, genomic structure and chromosomal location of RAB6KIFL, a human kinesin-like gene

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cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to chromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young

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der(5)t(5;7)(q11.2;p11.2): A new recurring abnormality in malignant myeloid disorders

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dic(5;17): a recurring abnormality in malignant myeloid disorders associated with mutations of TP53

scientific article published on 01 November 1997

miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia

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miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia

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miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia.

scientific article published on 24 June 2013

pMCT108.2 is a chimaeric clone which physically maps to human chromosome bands 9q33 (D9S203) and 18q21.1 (D18S24)

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t(1;3)(p36;p21) is a recurring therapy-related translocation

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t(3;21)(q26;q22): a recurring chromosomal abnormality in therapy-related myelodysplastic syndrome and acute myeloid leukemia

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β-Catenin induces T-cell transformation by promoting genomic instability

scientific article published on 26 December 2013