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List of works by John W Martens

4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer.

scientific article published on 7 August 2015

5-Fluorouracil treatment induces characteristic T>G mutations in human cancer

scientific article published on 08 October 2019

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium

scientific article published on 02 August 2012

APOBEC3B Gene Expression in Ductal Carcinoma In Situ and Synchronous Invasive Breast Cancer

scientific article published on 27 July 2019

An increased cell cycle gene network determines MEK and Akt inhibitor double resistance in triple-negative breast cancer

scientific article published on 16 September 2019

Association of microRNA-7 and its binding partner CDR1-AS with the prognosis and prediction of 1st-line tamoxifen therapy in breast cancer.

scientific article

Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer.

scientific article

Clinical performance of an analytically validated assay in comparison to microarray technology to assess PITX2 DNA-methylation in breast cancer

scientific article published in Scientific Reports

Clonality, Antigen Recognition, and Suppression of CD8+ T Cells Differentially Affect Prognosis of Breast Cancer Subtypes

scientific article published on 24 October 2019

Co-regulated gene expression of splicing factors as drivers of cancer progression

article

Comparative proteome analysis revealing an 11-protein signature for aggressive triple-negative breast cancer

scientific article published on 07 January 2014

Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

scientific article

Confirmation of a metastasis-specific microRNA signature in primary colon cancer.

scientific article published on 27 March 2018

Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

scientific article published in PLoS ONE

Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis

scientific article published on 19 December 2019

E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium.

scientific article published on 26 April 2018

Endocrine therapy resistance in estrogen receptor (ER)-positive breast cancer

scientific article published on 24 May 2016

Estrogen Receptor Pathway Activity Score to Predict Clinical Response or Resistance to Neoadjuvant Endocrine Therapy in Primary Breast Cancer

scientific article published on 14 November 2019

Evaluation of the ability of adjuvant tamoxifen-benefit gene signatures to predict outcome of hormone-naive estrogen receptor-positive breast cancer patients treated with tamoxifen in the advanced setting.

scientific article published on 10 July 2014

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

scientific article

Ferritin heavy chain in triple negative breast cancer: a favorable prognostic marker that relates to a cluster of differentiation 8 positive (CD8+) effector T-cell response

scientific article

Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus

scientific article

Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer

scientific article

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

scientific article

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

scientific article published on 27 March 2013

GATA3 mRNA expression, but not mutation, associates with longer progression-free survival in ER-positive breast cancer patients treated with first-line tamoxifen for recurrent disease.

scientific article

Genetic modifiers of CHEK2*1100delC-associated breast cancer risk

scientific article published on 06 October 2016

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

scientific article

High-throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium

scientific article published on 06 April 2016

IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer.

scientific article published on 22 January 2018

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Incorporating liquid biopsies into treatment decision-making: obstacles and possibilities

scientific article published on 03 June 2019

Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression

scientific article published on 31 March 2020

LAMP3 is involved in tamoxifen resistance in breast cancer cells through the modulation of autophagy.

scientific article published on 16 January 2014

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

Pan-cancer landscape of homologous recombination deficiency

scientific article published on 04 November 2020

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

article

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

scientific article

Poor prognosis of constitutive γ-H2AX expressing triple-negative breast cancers is associated with telomere length.

scientific article

Prognostic significance of nuclear expression of UMP-CMP kinase in triple negative breast cancer patients.

scientific article published on 25 August 2016

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

scientific article published on 18 October 2016

Proteome-wide onco-proteogenomic somatic variant identification in ER-positive breast cancer

scientific article published on 23 January 2019

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

scientific article published on 10 April 2018

Sensitive detection of mitochondrial DNA variants for analysis of mitochondrial DNA-enriched extracts from frozen tumor tissue

scientific article

Somatic Tumor Mutations Detected by Targeted Next Generation Sequencing in Minute Amounts of Serum-Derived Cell-Free DNA.

scientific article published on 18 May 2017

Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer

scientific article published on 27 September 2021

Targeted MS Assay Predicting Tamoxifen Resistance in Estrogen-Receptor-Positive Breast Cancer Tissues and Sera.

scientific article

The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer.

scientific article published on 07 October 2016

The Prevalence of CD146 Expression in Breast Cancer Subtypes and Its Relation to Outcome

scientific article published on 5 May 2018

The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies

scientific article published on 30 September 2019

The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact

scientific article published on 20 November 2019

The role of mitochondrial DNA in breast tumors

scientific article published on 22 March 2019

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

scientific article published on 01 March 2020

Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes

scientific article published on 05 July 2019

Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features

scientific article published on 25 January 2021

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