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List of works by Ian A Wilson

A Dynamic Switch in Inactive p38γ Leads to an Excited State on the Pathway to an Active Kinase

scientific article published on 13 December 2019

A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite

scientific article published on 16 September 2020

A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.

scientific article published on 28 March 2018

A cross-neutralizing antibody between HIV-1 and influenza virus

scientific article published on 22 March 2021

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

scientific article published on 31 October 2019

A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV

scientific article published on 03 April 2020

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

scientific article published on 21 September 2020

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

scientific article published on 04 December 2020

A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

scientific article published on 10 April 2019

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.

scientific article

A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.

scientific article published on 10 July 2017

A small-molecule fusion inhibitor of influenza virus is orally active in mice

scientific article published on 7 March 2019

An MPER antibody neutralizes HIV-1 using germline features shared among donors

scientific article published on 26 November 2019

An alternate conformation of HCV E2 neutralizing face as an additional vaccine target

scientific article published on 24 July 2020

An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain

scientific article published on 27 July 2020

An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen

scientific article published on 20 July 2020

Antibody responses to viral infections: a structural perspective across three different enveloped viruses

scientific article published on 18 March 2019

Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification

scientific article published on 17 April 2019

Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.

scientific article published on 17 November 2017

Broadly protective human antibodies that target the active site of influenza virus neuraminidase

scientific article published on 01 October 2019

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

scientific article published in 2021

Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide

scientific article published in Nature Communications

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.

scientific article

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

scientific article published on 03 August 2020

Cryo-EM structure of circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts

scientific article published on 10 October 2018

Design of protein-binding proteins from the target structure alone

scientific article published on 24 March 2022

Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses

scientific article published on 01 June 2020

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.

scientific article published on 23 February 2018

Functional human IgA targets a conserved site on malaria sporozoites

scientific article published on 01 June 2021

Genetic and structural insights into broad neutralization of hepatitis C virus by human V1-69 antibodies

scientific article published on 02 January 2019

HIV-1 vaccine design through minimizing envelope metastability

article

Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses

scientific article published on 28 May 2020

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

scientific article published on 15 June 2020

Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.

scientific article

Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape

scientific article published on 06 March 2020

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains

scientific article published on 04 February 2019

Potent peptidic fusion inhibitors of influenza virus

scientific article published on 28 September 2017

Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis

scientific article published on 18 December 2017

Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines

scientific article published on 15 April 2020

Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms

scientific article published on 05 May 2021

Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines

scientific article published on 11 May 2021

Structural Biology of Influenza Hemagglutinin: An Amaranthine Adventure

scientific article published on 22 September 2020

Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

scientific article published on 16 February 2021

Structural basis of a shared antibody response to SARS-CoV-2

scientific article

Structural basis of broad HIV neutralization by a vaccine-induced cow antibody

scientific article published on 27 May 2020

Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

scientific article published on 12 May 2022

Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

scientific article published on 29 May 2019

Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein

scientific article published on 09 March 2020

Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.

scientific article

Structures of single-layer β-sheet proteins evolved from β-hairpin repeats

scientific article published on 02 August 2019

Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins

scientific article published in 2024

The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen

article

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

scientific article

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

scientific article published on 27 May 2020

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