List of works - Megan L Peach

Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs

scientific article published on 02 December 2020

Conformational energy range of ligands in protein crystal structures: The difficult quest for accurate understanding

scientific article

Diacylglycerol lactones targeting the structural features that distinguish the atypical C1 domains of protein kinase C ζ and ι from typical C1 domains

scientific article

Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein

scientific article published on 18 September 2019

Experimental and Chemoinformatics Study of Tautomerism in a Database of Commercially Available Screening Samples

scientific article (publication date: 28 November 2016)

Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP.

scientific article published on 10 March 2017

Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina

scientific article published on 27 March 2017

Molecular Modeling of the Bacterial Chemotaxis Receptors Tar and Trg ⬇️

doctoral thesis by Megan L. Peach, University of Washington, 2001

Probing the hras-1Y i-motif with small molecules

scientific article published on 05 October 2018

QSAR modeling of imbalanced high-throughput screening data in PubChem

scientific article

SAVI, in silico generation of billions of easily synthesizable compounds through expert-system type rules

scientific article published on 11 November 2020

Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity

scientific article published on 28 March 2016

Synthesis and Biological Evaluation of Several Bryostatin Analogues Bearing a Diacylglycerol Lactone C-Ring.

scientific article published on 5 August 2016

Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone core

scientific article

Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP.

scientific article

Synthetic derivatives of the SUMO consensus sequence provide a basis for improved substrate recognition.

scientific article

Therapeutic Antibodies to Ganglioside GD2 Evolved from Highly Selective Germline Antibodies.

scientific article published in August 2017

α-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine Releasing Protein 3 (RasGRP3) Ligands.

scientific article

List of works by Megan L Peach

Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs

Conformational energy range of ligands in protein crystal structures: The difficult quest for accurate understanding

Diacylglycerol lactones targeting the structural features that distinguish the atypical C1 domains of protein kinase C ζ and ι from typical C1 domains

Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein

Experimental and Chemoinformatics Study of Tautomerism in a Database of Commercially Available Screening Samples

Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP.

Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina

Molecular Modeling of the Bacterial Chemotaxis Receptors Tar and Trg ⬇️

Probing the hras-1Y i-motif with small molecules

QSAR modeling of imbalanced high-throughput screening data in PubChem

SAVI, in silico generation of billions of easily synthesizable compounds through expert-system type rules

Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity

Synthesis and Biological Evaluation of Several Bryostatin Analogues Bearing a Diacylglycerol Lactone C-Ring.

Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone core

Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP.

Synthetic derivatives of the SUMO consensus sequence provide a basis for improved substrate recognition.

Therapeutic Antibodies to Ganglioside GD2 Evolved from Highly Selective Germline Antibodies.

α-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine Releasing Protein 3 (RasGRP3) Ligands.