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List of works by Giuseppina Tesco

APP substitutions V715F and L720P alter PS1 conformation and differentially affect Abeta and AICD generation

scientific article

Age-dependent effect of apolipoprotein E4 on functional outcome after controlled cortical impact in mice

scientific article

BACE is degraded via the lysosomal pathway

scientific article published on 20 July 2005

BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.

scientific article published on 2 February 2018

Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP).

scientific article published on 5 September 2003

Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity

scientific article

Generation of the β-Amyloid Peptide and the Amyloid Precursor Protein C-terminal Fragment γ Are Potentiated by FE65L1 ⬇️

scientific article (publication date: 19 December 2003)

Gga3 deletion and a GGA3 rare variant associated with late onset Alzheimer's disease trigger BACE1 accumulation in axonal swellings

scientific article published on 01 November 2020

Hypocapnia induces caspase-3 activation and increases Abeta production

scientific article published on January 2004

Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity

scientific article published on 15 July 2009

Protein aggregates and novel presenilin gene variants in idiopathic dilated cardiomyopathy

scientific article

Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1

scientific article published on 25 December 2008

Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion

scientific article published on 31 August 2006

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