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List of works by Kaspar P Locher

A catalytically essential motif in external loop 5 of the bacterial oligosaccharyltransferase PglB

scientific article

Asymmetric states of vitamin B12 transporter BtuCD are not discriminated by its cognate substrate binding protein BtuF ⬇️

scientific article published on March 8, 2012

Binding Specificities of Nanobody•Membrane Protein Complexes Obtained from Chemical Cross-Linking and High-Mass MALDI Mass Spectrometry.

scientific article published on 21 March 2018

Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1

scientific article published on 05 October 2020

Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B

scientific article published on 01 December 2019

Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins

scientific article published on 01 November 2021

High-mass matrix-assisted laser desorption ionization-mass spectrometry of integral membrane proteins and their complexes

scientific article

Molecular basis of lipid-linked oligosaccharide recognition and processing by bacterial oligosaccharyltransferase.

scientific article

Oligomeric States and Siderophore Binding of the Ligand‐Gated FhuA Protein that Forms Channels Across Escherichia Coli Outer Membranes ⬇️

scientific article published on August 1, 1997

On the efficiency of NHS ester cross-linkers for stabilizing integral membrane protein complexes.

scientific article

Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody

scientific article

Structural basis of nanobody-mediated blocking of BtuF, the cognate substrate-binding protein of the Escherichia coli vitamin B12 transporter BtuCD.

scientific article published on 30 October 2017

Structural basis of small-molecule inhibition of human multidrug transporter ABCG2

scientific article published on 02 April 2018

Structural basis of the molecular ruler mechanism of a bacterial glycosyltransferase.

scientific article published on 31 January 2018

Structural basis of transcobalamin recognition by human CD320 receptor

scientific journal article

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

scientific article

Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1.

scientific article published on 13 February 2018

Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP

scientific article published in 2024

Structure of bacterial oligosaccharyltransferase PglB bound to a reactive LLO and an inhibitory peptide

scientific article published in Scientific Reports

Structure of the human lipid exporter ABCB4 in a lipid environment

scientific article published on 23 December 2019

Structure of the human transcobalamin beta domain in four distinct states.

scientific article

Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation.

scientific article

Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism

scientific article published on 19 July 2021

Transmembrane Gate Movements in the Type II ATP-binding Cassette (ABC) Importer BtuCD-F during Nucleotide Cycle ⬇️

scientific article published on September 27, 2011

Two Stacked Heme Molecules in the Binding Pocket of the Periplasmic Heme-Binding Protein HmuT from Yersinia pestis ⬇️

scientific article published on November 26, 2010

X-ray structure of a bacterial oligosaccharyltransferase ⬇️

scientific article published on June 15, 2011

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