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List of works by Hiroyuki Aburatani

A comparison of differences in the gene expression profiles of phorbol 12-myristate 13-acetate differentiated THP-1 cells and human monocyte-derived macrophage

scientific article published on January 2004

A genome-scale CRISPR/Cas9 knockout screening reveals SH3D21 as a sensitizer for gemcitabine

scientific article published on 16 December 2019

A meta-clustering analysis indicates distinct pattern alteration between two series of gene expression profiles for induced ischemic tolerance in rats

scientific article published on 15 February 2005

A novel cell-cycle-indicator, mVenus-p27K-, identifies quiescent cells and visualizes G0-G1 transition

scientific article published on 6 February 2014

A novel sensitive detection method for DNA methylation in circulating free DNA of pancreatic cancer

scientific article published on 10 June 2020

A simple knowledge-based mining method for exploring hidden key molecules in a human biomolecular network ⬇️

scientific article published on September 15, 2012

A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer

scientific article published in Nature Communications

A wave of nascent transcription on activated human genes

scholarly article

ABCC13, an unusual truncated ABC transporter, is highly expressed in fetal human liver

scientific article

AKR1B10 in usual interstitial pneumonia: expression in squamous metaplasia in association with smoking and lung cancer.

scientific article published on 20 March 2008

ASCL1-coexpression profiling but not single gene expression profiling defines lung adenocarcinomas of neuroendocrine nature with poor prognosis

scientific article published on 6 July 2011

Aberrant DNA methylation of pregnane X receptor underlies metabolic gene alterations in the diabetic kidney

scientific article published on 6 December 2017

Aberrant promoter methylation of PPP1R3C and EFHD1 in plasma of colorectal cancer patients

scientific article

Aberrantly methylated genes in human papillary thyroid cancer and their association with BRAF/RAS mutation

scientific article published on 05 December 2013

Accumulation of molecular aberrations distinctive to hepatocellular carcinoma progression

scientific article published on 08 July 2020

Activation of Bmp2-Smad1 Signal and Its Regulation by Coordinated Alteration of H3K27 Trimethylation in Ras-Induced Senescence ⬇️

scientific article published on November 3, 2011

Adrenomedullin inhibits choroidal neovascularization via CCL2 in the retinal pigment epithelium.

scientific article

Allelic dosage analysis with genotyping microarrays.

scientific article

Allelic imbalances and homozygous deletion on 8p23.2 for stepwise progression of hepatocarcinogenesis.

scientific article published in February 2009

Amyloid precursor protein is a primary androgen target gene that promotes prostate cancer growth

scientific article published in January 2009

An Excess of CYP24A1, Lack of CaSR, and a Novel lncRNA Near the PTH Gene Characterize an Ectopic PTH-Producing Tumor ⬇️

scientific article published on 3 May 2017

An integrated map of p53-binding sites and histone modification in the human ENCODE regions

scientific article

An opposing view on WWOX protein function as a tumor suppressor

scientific article (publication date: 15 December 2003)

Analysis of mechanism for human gammadelta T cell recognition of nonpeptide antigens

scientific article published on August 2005

Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer

scientific article published on 3 May 2013

Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling

scientific article published in December 2002

Angiotensin receptor 1 blocker valsartan normalizes gene expression profiles of 3T3-L1 adipocytes altered by co-culture with LPS-treated RAW264.7 macrophages.

scientific article published on October 2012

Anti-glypican 3 antibodies cause ADCC against human hepatocellular carcinoma cells

scientific article

Anti-glypican 3 antibody as a potential antitumor agent for human liver cancer

scientific article

Anti-tumor activity of dual inhibition of phosphatidylinositol 3-kinase and MDM2 against clear cell ovarian carcinoma

scientific article published on 05 September 2019

Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423.

scientific article published on 04 February 2014

Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster

scientific article

BHD-associated kidney cancer exhibits unique molecular characteristics and a wide variety of variants in chromatin remodeling genes

scientific article published on 01 August 2018

BMP2 regulates Osterix through Msx2 and Runx2 during osteoblast differentiation

scientific article

BRCC3 mutations in myeloid neoplasms

scientific article published on 22 May 2015

Base editors for simultaneous introduction of C-to-T and A-to-G mutations

scientific article published on 01 June 2020

Biological characterization of soft tissue sarcomas

scientific article

CARAT: a novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays

scientific article

CASTIN: a system for comprehensive analysis of cancer-stromal interactome

scientific article

CDX1 confers intestinal phenotype on gastric epithelial cells via induction of stemness-associated reprogramming factors SALL4 and KLF5 ⬇️

scientific article published on October 29, 2012

COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis.

scholarly article

Calpain 6 is involved in microtubule stabilization and cytoskeletal organization

scientific article

Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure

scientific article published on 22 June 2009

Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis

scientific article published on 01 January 2022

Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure

scientific article published in Nature Communications

Caveolin-1, Id3a and two LIM protein genes are upregulated by estrogen in vascular smooth muscle cells

scientific article

Cell Type-specific Target Selection by Combinatorial Binding of Smad2/3 Proteins and Hepatocyte Nuclear Factor 4α in HepG2 Cells ⬇️

scientific article published on 06 June 2011

CellTree: an R/bioconductor package to infer the hierarchical structure of cell populations from single-cell RNA-seq data

scientific article

ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif ⬇️

scientific article published on July 15, 2011

Characteristics of Leiomyosarcoma: Induction of Hematogenous Metastasis by Isolated Uterine Mesenchymal Tumor Stem-like Cells

scientific article published on 01 March 2020

Characterization of the mouse Abcc12 gene and its transcript encoding an ATP-binding cassette transporter, an orthologue of human ABCC12.

scientific article published on May 2003

Chromosomal numerical abnormality profiles of gastrointestinal stromal tumors

scientific article published in February 2006

Classification of Epstein–Barr Virus–Positive Gastric Cancers by Definition of DNA Methylation Epigenotypes ⬇️

scientific article published on October 11, 2011

Clinical Application of Next-generation Sequencing for the Diagnosis of Lung Squamous Cell Carcinoma: Is It Primary or Secondary?

scientific article published on 12 February 2020

Clinical diagnosis of a double primary sigmoid colon cancer and metastatic tumour using a gene-targeted panel test: a case report

scientific article published on 25 April 2020

Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1)

scientific article published on 29 November 2020

Co-Activation of Epidermal Growth Factor Receptor and c-MET Defines a Distinct Subset of Lung Adenocarcinomas ⬇️

scientific article published on October 7, 2010

Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens

scientific article published on 05 March 2019

Comprehensive epigenome characterization reveals diverse transcriptional regulation across human vascular endothelial cells

scientific article published on 19 December 2019

Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior

scientific article

Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders

scientific article published on 11 November 2013

Constitutive Expression of Aryl Hydrocarbon Receptor in Keratinocytes Causes Inflammatory Skin Lesions

Constitutive activation of c-Met is correlated with c-Met overexpression and dependent on cell-matrix adhesion in lung adenocarcinoma cell lines

scientific article published on 22 October 2007

Control of histone H3 lysine 9 (H3K9) methylation state via cooperative two-step demethylation by Jumonji domain containing 1A (JMJD1A) homodimer

scientific article published on 8 November 2013

Cooperation of PU.1 With IRF8 and NFATc1 Defines Chromatin Landscapes During RANKL-Induced Osteoclastogenesis

scientific article published on 28 February 2019

Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells

scientific article published on 03 March 2020

Copy number variation: new insights in genome diversity

scientific article

Correction: Integrated Copy Number and Expression Analysis Identifies Profiles of Whole-Arm Chromosomal Alterations and Subgroups with Favorable Outcome in Ovarian Clear Cell Carcinomas

scientific article published on 6 July 2015

Correction: Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution

scientific article published on 19 May 2017

Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements

scientific article published on 10 April 2014

DGC-specific RHOA mutations maintained cancer cell survival and promoted cell migration via ROCK inactivation.

scientific article published in May 2018

DNA demethylation is associated with malignant progression of lower-grade gliomas

scientific article published in Scientific Reports

DNA methylation profiling of embryonic stem cell differentiation into the three germ layers

scientific article

DNA methylation status as a biomarker of anti-epidermal growth factor receptor treatment for metastatic colorectal cancer

scientific article

Defined lifestyle and germline factors predispose Asian populations to gastric cancer

scientific article published on 06 May 2020

Differential expression of S100A2 and S100A4 in lung adenocarcinomas: clinicopathological significance, relationship to p53 and identification of their target genes

scientific article

Differential regulation of CpG island methylation within divergent and unidirectional promoters in colorectal cancer

scientific article published on 02 March 2019

Differentiation and characterization of embryonic stem cells into three germ layers.

scientific article published on 27 February 2009

Direct evidence for pitavastatin induced chromatin structure change in the KLF4 gene in endothelial cells

scientific article

Distinct chromosomal bias of gene expression signatures in the progression of hepatocellular carcinoma.

scientific article published in October 2004

Distinct effects of Hoxa2 overexpression in cranial neural crest populations reveal that the mammalian hyomandibular-ceratohyal boundary maps within the styloid process.

scientific article published on 16 April 2015

Distinction in gene expression profiles of oligodendrogliomas with and without allelic loss of 1p.

scientific article published in June 2002

Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition

scientific article published on 30 November 2018

Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A.

scientific article

Dynamically and epigenetically coordinated GATA/ETS/SOX transcription factor expression is indispensable for endothelial cell differentiation

scientific article published on 17 March 2017

Dynamics of chromatin accessibility during TGF-β-induced EMT of Ras-transformed mammary gland epithelial cells.

scientific article

EG-13GENOME-WIDE METHYLATION ANALYSIS IDENTIFIES GENOMIC DNA DEMETHYLATION DURING MALIGNANT PROGRESSION OF GLIOMAS

scientific article published in November 2014

EWS-FLI1 regulates a transcriptional program in cooperation with Foxq1 in mouse Ewing sarcoma.

scientific article published on 18 July 2018

EYA4, deleted in a case with middle interhemispheric variant of holoprosencephaly, interacts with SIX3 both physically and functionally

scientific article

EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications

scientific article published on 6 March 2018

Echinomycin inhibits adipogenesis in 3T3-L1 cells in a HIF-independent manner.

scientific article published on 26 July 2017

Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers

scientific article

Engineered CRISPR-Cas9 nuclease with expanded targeting space

scientific article published in Science

Enhancement of bone formation ex vivo and in vivo by a helioxanthin-derivative

scientific article published on 9 April 2010

Enrichment of stem-like cell population comprises transformation ability of Epstein-Barr virus latent membrane protein 2A for non-transformed cells

scientific article

Epigenetic alteration to activate Bmp2-Smad signaling in Raf-induced senescence

scientific article published on February 2016

Epigenetic landscape influences the liver cancer genome architecture.

scientific article published on 24 April 2018

Epigenetic regulation of osteoclast differentiation.

scientific article published on December 2011

Epigenetic regulation of osteoclast differentiation: possible involvement of Jmjd3 in the histone demethylation of Nfatc1.

scientific article published in November 2011

Epigenetically coordinated GATA2 binding is necessary for endothelium-specificendomucinexpression ⬇️

scientific article published on June 10, 2011

Epigenomic Regulation of Smad1 Signaling During Cellular Senescence Induced by Ras Activation

scientific article published on January 2016

Epstein-Barr virus infection as an epigenetic driver of tumorigenesis

scientific article published on 03 July 2012

Erratum: Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

scientific article published on 01 May 2016

Establishment of mice expressing EGFP in the placode‐derived inner ear sensory cell lineage and FACS‐array analysis focused on the regional specificity of the otocyst ⬇️

scientific article published on December 1, 2010

Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment

scientific article published on 28 February 2015

Exploration of liver cancer genomes

scientific article published on 28 January 2014

Expression and functions of transmembrane mucin MUC13 in ovarian cancer.

scientific article

Expression and localization of P1 promoter-driven hepatocyte nuclear factor-4alpha (HNF4alpha) isoforms in human and rats

scientific article

Expression imbalance map: a new visualization method for detection of mRNA expression imbalance regions

scientific article published on 18 March 2003

Expression of PRMT5 in lung adenocarcinoma and its significance in epithelial-mesenchymal transition

scientific article published on 28 February 2014

Extracellular Acidic pH Activates the Sterol Regulatory Element-Binding Protein 2 to Promote Tumor Progression.

scientific article published in February 2017

Ezetimibe decreases SREBP-1c expression in liver and reverses hepatic insulin resistance in mice fed a high-fat diet ⬇️

scientific article published on August 2, 2010

FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling

scientific journal article

FREQUENT H3F3A K27M MUTATIONS IN THALAMIC GLIOMAS FROM YOUNG ADULT PATIENTS.

scientific article published in July 2014

Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPARα-independent mechanisms ⬇️

scientific article published on April 21, 2011

Fish oil feeding alters liver gene expressions to defend against PPARalpha activation and ROS production

scientific article published in February 2002

Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier: high affinity transporter for thyroxine

scientific article

Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation

scientific article published on 22 May 2006

Fusion kinases identified by genomic analyses of sporadic microsatellite instability-high colorectal cancers

scientific article published on 02 October 2018

GADD45βDetermines Chemoresistance and Invasive Growth of Side Population Cells of Human Embryonic Carcinoma ⬇️

scientific article published on March 14, 2010

GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation

scientific article published in August 2013

GE-15CLONAL EVOLUTION AND INTRATUMORAL HETEROGENEITY OF LOW-GRADE GLIOMA GENOMES

scientific article published in November 2014

GENE-10. CHARACTERISTIC MOLECULAR PROFILE CHANGES IN PRIMARY AND RECURRENT GLIOMAS DEPENDING ON THEIR HISTOPATHOLOGY

scientific article published on 6 November 2017

GENE-60. INTEGRATED GENOMIC AND EPIGENOMIC ANALYSIS FOR HEMANGIOBLASTOMAS OF THE CENTRAL NERVOUS SYSTEM

scientific article published on 6 November 2017

GENO-27GENOMIC CHARACTERIZATION OF PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA REVEALS PREDOMINANT NONSYNONYMOUS SOMATIC MUTATIONS OF MYD88 AND PIM1 GENES.

scientific article

Gastric Cancer With Primitive Enterocyte Phenotype: An Aggressive Subgroup of Intestinal-type Adenocarcinoma

scientific article published on 12 May 2017

Gene expression profile after peroxisome proliferator activator receptor-gamma ligand administration in dextran sodium sulfate mice

scientific article published on 01 November 2002

Gene expression profile revealed different effects of angiotensin II receptor blockade and angiotensin-converting enzyme inhibitor on heart failure.

scientific article published in December 2003

Gene expression profiling and identification of novel prognostic marker genes in neuroblastoma

scientific article published in June 2004

Gene expression profiling of mouse growth plate cartilage by laser microdissection and microarray analysis

scientific article

Gene expression profiling of non-alcoholic steatohepatitis using gene set enrichment analysis

article

Generation of an anti-desmoglein 3 antibody without pathogenic activity of pemphigus vulgaris for therapeutic application to squamous cell carcinoma

scientific article published on 01 December 2018

Genetic Testing Distinguishes Multiple Chondroid Chordomas with Neuraxial Bone Metastases from Multicentric Tumors

scientific article published on 28 November 2020

Genetic and epigenetic aberrations occurring in colorectal tumors associated with serrated pathway

scientific article published on 28 October 2015

Genetic and epigenetic basis of hepatoblastoma diversity

scientific article published on 20 September 2021

Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling

scientific article published on 31 January 2018

Genome assembly comparison identifies structural variants in the human genome.

scientific article

Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells

scientific article

Genome-wide analysis revealed that DZNep reduces tubulointerstitial fibrosis via down-regulation of pro-fibrotic genes

scientific article published on 28 February 2018

Genome-wide approaches reveal functional interleukin-4-inducible STAT6 binding to the vascular cell adhesion molecule 1 promoter

scientific article

Genome-wide approaches reveal functional vascular endothelial growth factor (VEGF)-inducible nuclear factor of activated T cells (NFAT) c1 binding to angiogenesis-related genes in the endothelium

scientific article published on 25 August 2014

Genome-wide detection of human copy number variations using high-density DNA oligonucleotide arrays

scientific article

Genome-wide gene expression analysis for induced ischemic tolerance and delayed neuronal death following transient global ischemia in rats

scientific article published on 01 February 2004

Genome-wide maps of mono- and di-nucleosomes of Aspergillus fumigatus

scientific article published in July 2009

Genome-wide maps of mononucleosomes and dinucleosomes containing hyperacetylated histones of Aspergillus fumigatus

scientific article

Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism

scientific article

Genome-wide single nucleotide polymorphism arrays as a diagnostic tool in patients with synchronous endometrial and ovarian cancer.

scientific article

Genomewide comprehensive analysis reveals critical cooperation between Smad and c-Fos in RANKL-induced osteoclastogenesis

scientific article published in May 2015

Genomic Approach Towards Personalized Anticancer Drug Therapy ⬇️

scientific article published on January 1, 2012

Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population.

scientific article

Genomic approach for the understanding of dynamic aspect of chromosome behavior

scientific article published in January 2006

Genomic characterization of primary central nervous system lymphoma

scientific article published on 12 January 2016

Genomic profiling of multiple primary cancers including synchronous lung adenocarcinoma and bilateral malignant mesotheliomas: Identification of a novel BAP1 germline variant

scientific article published on 24 June 2020

Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas

scientific article

Global Mapping of Cell Type–Specific Open Chromatin by FAIRE-seq Reveals the Regulatory Role of the NFI Family in Adipocyte Differentiation ⬇️

scientific article published on October 20, 2011

Global and non‐random CpG‐island methylation in gastric carcinoma associated with Epstein‐Barr virus ⬇️

scientific article published on January 1, 2003

Global epigenomic analysis indicates protocadherin-7 activates osteoclastogenesis by promoting cell-cell fusion

scientific article published on 13 November 2014

Global gene expression analysis of gastric cancer by oligonucleotide microarrays.

scientific article published on January 2002

Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

scientific article published on April 2004

Global variation in copy number in the human genome

scientific article

Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.

scientific article

Glypican 3-expressing gastric carcinoma: distinct subgroup unifying hepatoid, clear-cell, and alpha-fetoprotein-producing gastric carcinomas

scientific article published on 19 February 2009

Glypican-3 expression in clear cell adenocarcinoma of the ovary

scientific article

Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling

scientific article

H3F3A K27M mutations in thalamic gliomas from young adult patients

scientific article

H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation.

scientific article published on November 2015

Hepatic gene induction in murine bone marrow after hepatectomy

scientific article

High expression of ABCG2 induced by EZH2 disruption has pivotal roles in MDS pathogenesis

scientific article

High-density oligonucleotide array with sub-kilobase resolution reveals breakpoint information of submicroscopic deletions in nevoid basal cell carcinoma syndrome

scientific article

High-resolution characterization of a hepatocellular carcinoma genome

scientific article

High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array

scientific article published on 26 September 2006

Histone H2A T120 Phosphorylation Promotes Oncogenic Transformation via Upregulation of Cyclin D1.

scientific article published on October 2016

Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch

scientific article published on 19 April 2018

Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells

scientific article published on 13 May 2010

Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin/TCF.

scientific article

Hypoxia increases the motility of lung adenocarcinoma cell line A549 via activation of the epidermal growth factor receptor pathway

scientific article published on April 2007

Hypoxia-Inducible Factor-1α Activates the Transforming Growth Factor-β/SMAD3 Pathway in Kidney Tubular Epithelial Cells

scientific article published on 09 September 2016

IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis

scientific journal article

IMMU-58. REDUCED NEOANTIGEN EXPRESSION AS A POSSIBLE IMMUNE EVASION MECHANISM DURING GLIOMA PROGRESSION

Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma

scientific article published on 28 July 2006

Identification of CCDC6-RET Fusion in the Human Lung Adenocarcinoma Cell Line, LC-2/ad ⬇️

scientific article published on December 1, 2012

Identification of Cystatin SN as a novel tumor marker for colorectal cancer

scientific article

Identification of MYLK3 mutations in familial dilated cardiomyopathy

scientific article published on 13 December 2017

Identification of Nedd9 as a TGF-β-Smad2/3 Target Gene Involved in RANKL-Induced Osteoclastogenesis by Comprehensive Analysis.

scientific article

Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target

scientific article (publication date: June 2006)

Identification of Toll-like receptor 3 as a potential therapeutic target in clear cell renal cell carcinoma.

scientific article

Identification of a link between Wnt/β-catenin signalling and the cell fusion pathway

scientific article

Identification of chromosomal aberrations of metastatic potential in colorectal carcinoma

scientific article published on 01 May 2010

Identification of genes associated with dedifferentiation of hepatocellular carcinoma with expression profiling analysis.

scientific article

Identification of genes preferentially methylated in hepatitis C virus-related hepatocellular carcinoma

scientific article published on 27 February 2010

Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma

scientific article published in April 2004

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

scientific article

Immune suppressor factor confers stromal cell line with enhanced supporting activity for hematopoietic stem cells

scientific article published on 6 December 2005

Immunogenetic Profiling for Gastric Cancers Identifies Sulfated Glycosaminoglycans as Major and Functional B Cell Antigens in Human Malignancies.

scientific article published in August 2017

Impact of AAV2 and Hepatitis B Virus Integration Into Genome on Development of Hepatocellular Carcinoma in Patients with Prior Hepatitis B Virus Infection

scientific article published on 18 July 2019

Increased hepatic expression of ganglioside-specific sialidase, NEU3, improves insulin sensitivity and glucose tolerance in mice.

scientific article

Induction of hyper Th1 cell-type immune responses by dendritic cells lacking the suppressor of cytokine signaling-1 gene

scientific article published on 01 April 2005

Influence of polyunsaturated fatty acid on gene expression in HepG2 cells

scientific article published on 01 January 2002

Inhibition of histone demethylase JMJD1A improves anti-angiogenic therapy and reduces tumor-associated macrophages.

scientific article published on 14 March 2013

Initialization of epithelial cells by tumor cells in a metastatic microenvironment

scientific article published on 03 February 2020

Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution

scientific article

Integrated copy number and expression analysis identifies profiles of whole-arm chromosomal alterations and subgroups with favorable outcome in ovarian clear cell carcinomas

scientific article published on 4 June 2015

Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma

scientific article published on 3 July 2015

Integrated molecular analysis of adult T cell leukemia/lymphoma.

scientific article published on 5 October 2015

Integrated molecular analysis of clear-cell renal cell carcinoma

scientific article

Integrated molecular profiling of juvenile myelomonocytic leukemia.

scientific article published on 2 February 2018

Integrative analysis of FOXP1 function reveals a tumor-suppressive effect in prostate cancer

scientific article

Interleukin-1beta expression in human gastric carcinoma with Epstein-Barr virus infection

scientific article

Intermediate methylation epigenotype and its correlation to KRAS mutation in conventional colorectal adenoma

scientific article

International network of cancer genome projects

scientific article

Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues

scientific article published on August 2005

Involvement of proteasome β1i subunit, LMP2, on development of uterin leiomyosarcma.

scientific article published on September 2011

In vivo effects of mutant RHOA on tumor formation in an orthotopic inoculation model

scientific article published on 03 September 2019

JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis

scientific article published on 7 May 2015

LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA

scientific article published on 01 November 2019

Life style-related diseases of the digestive system: gene expression in nonalcoholic steatohepatitis patients and treatment strategies.

scientific article published on 06 October 2007

Long Noncoding RNA JHDM1D-AS1 Promotes Tumor Growth by Regulating Angiogenesis in Response to Nutrient Starvation

scientific article published on 26 June 2017

Loss of YAP1 defines neuroendocrine differentiation of lung tumors.

scientific article published on 15 July 2016

Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features ⬇️

scientific article published on January 4, 2013

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster

scientific article published on 30 November 2020

MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.

scientific article published on 21 September 2016

Marked Induction of c-Maf Protein during Th17 Cell Differentiation and Its Implication in Memory Th Cell Development ⬇️

scientific article published on March 14, 2011

Mechanistic background and clinical applications of indocyanine green fluorescence imaging of hepatocellular carcinoma

scientific article published on 20 November 2013

Mesenchymal Tumors with RREB1-MRTFB Fusion Involving the Mediastinum: Extra-Glossal Ectomesenchymal Chondromyxoid Tumors?

scientific article published on 28 January 2020

Metallothionein is upregulated by hypoxia and stabilizes hypoxia-inducible factor in the kidney

scientific article

Methionine metabolism regulates maintenance and differentiation of human pluripotent stem cells.

scientific article

Methylation epigenotypes and genetic features in colorectal laterally spreading tumors.

scientific article

Methylation screening of reciprocal genome-wide UPDs identifies novel human-specific imprinted genes

scientific article published on 18 May 2011

Microarray-based analysis for hepatocellular carcinoma: from gene expression profiling to new challenges

scientific article published on March 2007

Molecular Pathology and Novel Clinical Therapy for Uterine Leiomyosarcoma

scientific article published on October 2016

Molecular Predictors of Sensitivity to the MET Inhibitor PHA665752 in Lung Carcinoma Cells ⬇️

scientific article published on September 1, 2010

Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer

scientific article published on 01 April 2015

Molecular classification and diagnostics of upper urinary tract urothelial carcinoma

scientific article published on 01 June 2021

Molecular mechanisms of uterine leiomyosarcomas: involvement of defect in LMP2 expression.

scientific article published on 22 July 2008

Molecular targets for liver cancer therapy: From screening of target genes to clinical trials

scientific article published on 25 September 2009

Multi-tumor analysis of cancer-stroma interactomes of patient-derived xenografts unveils the unique homeostatic process in renal cell carcinomas

scientific article published on 21 October 2021

Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome

scientific article

Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ

scientific journal article

Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma

scientific article

NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program

scientific article published on 14 August 2017

NFIA differentially controls adipogenic and myogenic gene program through distinct pathways to ensure brown and beige adipocyte differentiation

scientific article published on 29 September 2020

Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1.

scientific article

Neoantigen load and HLA-class I expression identify a subgroup of tumors with a T-cell-inflamed phenotype and favorable prognosis in homologous recombination-proficient high-grade serous ovarian carcinoma

scientific article published on 01 May 2020

Network-based analysis for identification of candidate genes for colorectal cancer progression

scientific article published on 30 May 2016

Noise reduction from genotyping microarrays using probe level information.

scientific article published on January 2006

Non-diethylstilbestrol exposed vaginal clear cell adenocarcinoma has a common molecular profile with ovarian clear cell adenocarcinoma: A case report

scientific article published on 5 June 2014

Novel lnc RNA regulated by HIF-1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia

scientific article

Novel p53 target gene FUCA1 encodes a fucosidase and regulates growth and survival of cancer cells

scientific article published on 21 March 2016

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming ⬇️

scientific article published on July 10, 2012

Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos

scientific article

Oncofetal protein glypican-3 in testicular germ-cell tumor

scientific article published on 04 August 2006

Organoid-based ex vivo reconstitution of Kras-driven pancreatic ductal carcinogenesis

scientific article published on 22 June 2019

Overexpression of MUC13 is associated with intestinal-type gastric cancer

scientific article

Overexpression of cadherins suppresses pulmonary metastasis of osteosarcoma in vivo

scientific article

Overexpression of p54nrb/NONO induces differential EPHA6 splicing and contributes to castration-resistant prostate cancer growth.

scientific article published on 8 January 2018

Overexpression of the aldo-keto reductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas.

scientific article

P28. Prediction of prognosis for small cell lung cancer based on genome-wide methylation analyses.

scientific article

PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt

scientific article

PPARα activation directly upregulates thrombomodulin in the diabetic retina

scientific article published on 02 July 2020

PPARβ/δ activation of CD300a controls intestinal immunity

scientific article

PRC2 overexpression and PRC2-target gene repression relating to poorer prognosis in small cell lung cancer

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Pemafibrate, a selective PPARα modulator, prevents non-alcoholic steatohepatitis development without reducing the hepatic triglyceride content

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Peroxisome proliferator-activated receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent acute colitis

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Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling

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Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2

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Pitx2 prevents osteoblastic transdifferentiation of myoblasts by bone morphogenetic proteins

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Plasma Pentraxin3 is a novel marker for nonalcoholic steatohepatitis (NASH).

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Population-genetic nature of copy number variations in the human genome

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Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease

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Potential biomarker for human uterine leiomyosarcoma

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Potential diagnostic biomarkers: differential expression of LMP2/β1i and cyclin B1 in human uterine leiomyosarcoma

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Potential role of LMP2 as an anti‐oncogenic factor in human uterine leiomyosarcoma: Morphological significance of calponin h1 ⬇️

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Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy.

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Profiling of Target Molecules for Immunotherapy in Mesenchymal Tumors

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Prognostic significance of CpG island methylator phenotype in surgically resected small cell lung carcinoma

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Promoter-wide analysis of Smad4 binding sites in human epithelial cells

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Publisher Correction: Base editors for simultaneous introduction of C-to-T and A-to-G mutations

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Publisher Correction: DNA demethylation is associated with malignant progression of lower-grade gliomas

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RHOA mutation in diffuse-type gastric cancer: a comparative clinicopathology analysis of 87 cases

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RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer

scientific article published on February 2015

Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

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Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms

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Reducing false positives in molecular pattern recognition

scientific article published in January 2003

Regulation of SREBP1c gene expression in skeletal muscle: role of retinoid X receptor/liver X receptor and forkhead-O1 transcription factor

scientific article published on 17 January 2008

Resistin-like molecule β is abundantly expressed in foam cells and is involved in atherosclerosis development

scientific article published on 23 May 2013

SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.

scientific article published on 12 February 2016

Screening of liver-targeted drugs

scientific article published on June 2008

Selective expression of a subset of neuronal genes in oligodendroglioma with chromosome 1p loss.

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Signals from intra-abdominal fat modulate insulin and leptin sensitivity through different mechanisms: neuronal involvement in food-intake regulation

scientific article published in March 2006

Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control

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Smad4 is required to inhibit osteoclastogenesis and maintain bone mass

scientific article published on 12 October 2016

Small lung tumor biopsy samples are feasible for high quality targeted next generation sequencing

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Spatial and temporal expansion of intrahepatic metastasis by molecularly-defined clonality in multiple liver cancers

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Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis

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Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma

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Spinal solitary fibrous tumor of the neck: Next-generation sequencing-based analysis of genomic aberrations

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Spontaneous Transdifferentiation from Small Cell Lung Carcinoma to Squamous Cell Carcinoma

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Spontaneous Transformation from EGFR and ALK Wild-Type Lung Adenocarcinoma to Neuroendocrine Carcinoma

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Stable knockdown of S100A4 suppresses cell migration and metastasis of osteosarcoma.

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TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed

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Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells

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The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension

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The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis

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The G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) facilitates tumor development by serving as an extracellular pH sensor ⬇️

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The first case of gastric carcinoma with NTRK rearrangement: identification of a novel ATP1B-NTRK1 fusion

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The frequency of neoantigens per somatic mutation rather than overall mutational load or number of predicted neoantigens per se is a prognostic factor in ovarian clear cell carcinoma.

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The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma

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The mammalian homolog of the Drosophila discs large tumor suppressor protein up-regulates expression of the ELR+ CXC chemokine Scyb5.

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The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop

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The role of NF-κB signaling in the maintenance of pluripotency of human induced pluripotent stem cells

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Three DNA methylation epigenotypes in human colorectal cancer

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Thrombomodulin, a novel molecule regulating inorganic phosphate-induced vascular smooth muscle cell calcification.

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Tissue-specific demethylation in CpG-poor promoters during cellular differentiation

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Topological and Functional Discovery in a Gene Coexpression Meta-Network of Gastric Cancer

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Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

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Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells

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Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice

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Transduced caudal-type homeobox (CDX) 2/CDX1 can induce growth inhibition on CDX-deficient gastric cancer by rapid intestinal differentiation.

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Trib1 promotes acute myeloid leukemia progression by modulating the transcriptional programs of Hoxa9

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Tumor suppressor miR-22 determines p53-dependent cellular fate through post-transcriptional regulation of p21.

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Two distinct gene expression signatures in pediatric acute lymphoblastic leukemia with MLL rearrangements.

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Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation

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Two subtypes of colorectal tumor with distinct molecular features in familial adenomatous polyposis.

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Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy

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Utility of ATRX immunohistochemistry in diagnosis of adult diffuse gliomas

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Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis

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Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency

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Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.

scientific article published on 11 April 2016

p63 - Key molecule in the early phase of epithelial abnormality in idiopathic pulmonary fibrosis

scientific article published on 10 April 2007

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