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List of works by Roberto Zoncu

A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold

scientific article published on 30 July 2018

Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition

scientific article published on 08 July 2019

ER-lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann-Pick type C

scientific article published on 23 September 2019

Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex.

scientific article published in March 2017

Lysosomal recycling of amino acids affects ER quality control

scientific article published on 26 June 2020

NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease

scientific article published on 11 March 2020

Rhomboids Distort Time and Space: Accelerated Proteolysis through Membrane Disruption

scientific article published on 12 April 2019

Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex

scientific article

Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD

scientific article published on 26 August 2020

The lysosome as a cellular centre for signalling, metabolism and quality control

scientific article published on 02 January 2019

Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth

scientific article

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