List of works - Barbara Malawska

1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease

scientific article published on 26 November 2019

2,3-dihydro-1H-cyclopenta[b]quinoline derivatives as acetylcholinesterase inhibitors-synthesis, radiolabeling and biodistribution

scientific article

3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one and pregabalin attenuate tactile allodynia in the mouse model of chronic constriction injury

scientific article published on 21 May 2015

Advances toward multifunctional cholinesterase and β-amyloid aggregation inhibitors

scientific article published on 19 September 2017

Analgesic activity of 3-mono-substituted derivatives of dihydrofuran-2-one in experimental rodent models of pain

scientific article published in September 2009

Analgesic and anticonvulsant activity of new derivatives of 2-substituted 4-hydroxybutanamides in mice

scientific article published on 01 January 2012

Analgesic, anticonvulsant and antioxidant activities of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one dihydrochloride in mice

scientific article published on 28 December 2011

Analgesic, antioedematous and antioxidant activity of γ-butyrolactone derivatives in rodents

scientific article published on August 2012

Antiallodynic and antihyperalgesic activity of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one compared to pregabalin in chemotherapy-induced neuropathic pain in mice.

scientific article published on 12 April 2014

Antiarrhythmic and α-Adrenoceptor Antagonistic Properties of Novel Arylpiperazine Derivatives of Pyrrolidin-2-one.

scientific article published on 2 November 2015

Antiarrhythmic properties of phenylpiperazine derivatives of phenytoin with α₁-adrenoceptor affinities

scientific article published on 13 February 2012

Antidepressant-like activity of the phenylpiperazine pyrrolidin-2-one derivatives in mice.

scientific article published in January 2011

Application of RP-TLC technique for the determination of dissociation constants of 1-substituted pyrrolidin-2-one derivatives

scientific article

Application of a Library of Artificial Receptors Formed by Self-Organization ofN-Lipidated Peptides Immobilized on Cellulose for Preliminary Studies of Binding ofN-Phenylpiperazines

Application of a library of artificial receptors formed by the self-organization of N-lipidated peptides immobilized on cellulose in studying the effects of the incorporation of a fluorine atom.

scientific article

Application of computational methods for the design of BACE-1 inhibitors: validation of in silico modelling.

scientific article published on 24 March 2014

Biphenylalkoxyamine Derivatives-Histamine H Receptor Ligands with Butyrylcholinesterase Inhibitory Activity

scientific article published on 11 June 2021

Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands.

scientific article published on 20 April 2016

Corrigendum to "Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands" [Eur. J. Med. Chem. 185 (2020) 111785]

scientific article published on 10 August 2020

Design, Synthesis and Evaluation of Novel 2-(Aminoalkyl)-isoindoline-1,3-dione Derivatives as Dual-Binding Site Acetylcholinesterase Inhibitors

scientific article published on 30 March 2012

Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents.

scientific article published on 18 January 2018

Design, Synthesis, and Biological Evaluation of 2-(Benzylamino-2-Hydroxyalkyl)Isoindoline-1,3-Diones Derivatives as Potential Disease-Modifying Multifunctional Anti-Alzheimer Agents.

scientific article published on 7 February 2018

Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation

scientific article published on 26 September 2016

Design, synthesis and pharmacological evaluation of alpha-substituted N-benzylamides of gamma-hydroxybutyric acid with potential GABA-ergic activity. Part 6. Search for new anticonvulsant compounds.

scientific article published in March 2007

Design, synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxy-propyl]-3,3-diphenylpyrrolidin-2-one derivatives with antiarrhythmic, antihypertensive, and alpha-adrenolytic activity.

scientific article published on 22 April 2009

Determination of lipophilicity of alpha-(4-phenylpiperazine) derivatives of N-benzylamides using chromatographic and computational methods

scientific article

Determination of lipophilicity of γ-butyrolactone derivatives with anticonvulsant and analgesic activity using micellar electrokinetic chromatography

scientific article

Development of an in-vivo active reversible butyrylcholinesterase inhibitor.

scientific article published on 21 December 2016

Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and β-amyloid aggregation inhibitors with neuroprotective properties

scientific article

Development, recent achievements and current directions of research into GABA uptake inhibitors

scientific article published on 10 October 2019

Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines.

scientific article

Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives-Anticancer and Cholinesterase-Inhibiting Activity

scientific article published on 03 June 2020

Dual-acting diether derivatives of piperidine and homopiperidine with histamine H(3) receptor antagonistic and anticholinesterase activity

scientific article published on 02 May 2012

Electrophoretically mediated microanalysis technique as a tool for the rapid screening of novel acetylcholinesterase inhibitors.

scientific article published in July 2009

Estimation of phospholipophilicity of 1-[3-(arylpiperazin-1-yl)-propyl]-pyrrolidin-2-one derivatives on immobilized artificial membrane stationary phase and its correlation with biological data

scientific article

Estimation of the lipophilicity of antiarrhythmic and antihypertensive active 1-substituted pyrrolidin-2-one and pyrrolidine derivatives

scientific article

Evaluation of anticonvulsant activity of novel pyrrolidin-2-one derivatives

scientific article published on 06 March 2014

Evaluation of antinociceptive and antioxidant properties of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one in mice

scientific article published on 14 March 2013

Evaluation of anxiolytic-like, anticonvulsant, antidepressant-like and antinociceptive properties of new 2-substituted 4-hydroxybutanamides with affinity for GABA transporters in mice.

scientific article published on 10 July 2013

Hybrid approach to structure modeling of the histamine H3 receptor: Multi-level assessment as a tool for model verification

scientific article published on 5 October 2017

Influence of new gamma-hydroxybutyric acid amide analogues on the central nervous system activity in mice.

scientific article published in November 2002

Investigation into new anticonvulsant derivatives of alpha-substituted N-benzylamides of gamma-hydroxy- and gamma-acetoxybutyric acid. Part 5: search for new anticonvulsant compounds

scientific article

Investigation of lipophilicity of anticancer-active thioquinoline derivatives

scientific article

Isoindoline-1,3-dione derivatives targeting cholinesterases: design, synthesis and biological evaluation of potential anti-Alzheimer's agents

scientific article published on 9 February 2015

Lipophilic properties of anti-Alzheimer's agents determined by micellar electrokinetic chromatography and reversed-phase thin-layer chromatography.

scientific article published on 15 March 2017

Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease

scientific article published on 01 December 2020

Multiple Ligands Targeting Cholinesterases and β-Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore

scientific article

New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition

scientific article published on 05 December 2019

New tacrine analogs as acetylcholinesterase inhibitors - theoretical study with chemometric analysis.

scientific article published on 4 March 2013

Novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties as cholinesterases inhibitors.

scientific article published on 17 September 2010

Novel application of capillary electrophoresis with a liposome coated capillary for prediction of blood-brain barrier permeability

scientific article published on 11 April 2020

Novel carbamate derivatives as selective butyrylcholinesterase inhibitors.

scientific article published on 3 March 2018

Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice

scientific article published on 29 December 2019

Novel multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease.

scientific article published on 31 January 2018

Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT6 receptor antagonists. Design, synthesis and biological evaluation.

scientific article published on 11 August 2016

Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer's disease

scientific article published on 21 August 2020

Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease.

scientific article published on January 2015

Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment

scientific article

SEARCH FOR POTENTIAL CHOLINESTERASE INHIBITORS FROM THE ZINC DATABASE BY VIRTUAL SCREENING METHOD.

scientific article

Search for anticonvulsant and analgesic active derivatives of dihydrofuran-2(3H)-one

scientific article published on 31 August 2012

Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives

scientific article published on 26 June 2019

Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands

scientific article published on 17 October 2019

Search for new potential anticonvulsants with anxiolytic and antidepressant properties among derivatives of 4,4-diphenylpyrrolidin-2-one

scientific article published on 22 September 2016

Stereocontrolled synthesis of the enantiomers of 1-[2-hydroxy-3-(4-phenyl-1-piperazinyl)-propyl]-pyrrolidin-2-one

article published in 2001

Structure-Activity Relationship Studies of a Number of α1 -Adrenoceptor Antagonists and Antiarrhythmic Agents.

scientific article

Structure-based search for new inhibitors of cholinesterases.

scientific article

Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy.

scientific article

Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease.

scientific article published on 14 May 2016

Synthesis and biological evaluation of new derivatives of 2-substituted 4-hydroxybutanamides as GABA uptake inhibitors

scientific article published on 04 November 2010

Synthesis and development of new 2-substituted 1-[3-(4-arylpiperazin-1-yl)propyl]-pyrrolidin-2-one derivatives with antiarrhythmic, hypotensive, and alpha-adrenolytic activity

scientific article published on 21 September 2005

Synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxypropyl]-pyrrolidin-2-one derivatives with anti-arrhythmic, hypotensive, and alpha-adrenolytic activity

scientific article published on 01 September 2007

Synthesis and pharmacological evaluation of new 1-[3-(4-phenylpiperazin-1-yl)-propyl]- and 1-[3-(4-phenylpiperidine)-propyl]- 3-aryl-3-alkyl-pyrrolidin-2-one derivatives with antiarrhythmic and antihypertensive activity

scientific article published in November 2009

Synthesis and pharmacological evaluation of pyrrolidin-2-one derivatives as antiarrhythmic, antihypertensive and alpha-adrenolytic agents

scientific article published in January 2010

Synthesis and pharmacological properties of new GABA uptake inhibitors.

scientific article published in January 2012

Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo

scientific article published on 27 March 2015

Synthesis of novel N-alkyl carbamates of a-substituted amides of g-hydroxybutyric acid as potential acetylcholinesterase inhibitors

scientific article published in December 2004

Synthesis of novel N-benzyl substituted piperidine amides of 1H-indole-5-carboxylic acid as potential inhibitors of cholinesterases.

scientific article published in May 2012

Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta.

scientific article

Synthesis, antiarrhythmic, and antihypertensive effects of novel 1-substituted pyrrolidin-2-one and pyrrolidine derivatives with adrenolytic activity.

scientific article published in March 2002

Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.

scientific article

Tetrahydroacridine derivatives with fluorobenzoic acid moiety as multifunctional agents for Alzheimer's disease treatment

scientific article published on 5 May 2017

Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy

scientific article published on 23 November 2016

The study of the lipophilicity of alpha-(4-phenylpiperazin-1-yl)-gamma-phthalimidobutyramides using chromatographic and computational methods

scientific article

Therapeutic strategies for Alzheimer's disease in clinical trials.

scientific article published on 05 August 2015

Trends in the development of new drugs for treatment of benign prostatic hyperplasia

scientific article published on January 2006

α-Adrenoceptor antagonistic and hypotensive properties of novel arylpiperazine derivatives of pyrrolidin-2-one

scientific article published on 09 March 2015

List of works by Barbara Malawska

1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease

2,3-dihydro-1H-cyclopenta[b]quinoline derivatives as acetylcholinesterase inhibitors-synthesis, radiolabeling and biodistribution

3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one and pregabalin attenuate tactile allodynia in the mouse model of chronic constriction injury

Advances toward multifunctional cholinesterase and β-amyloid aggregation inhibitors

Analgesic activity of 3-mono-substituted derivatives of dihydrofuran-2-one in experimental rodent models of pain

Analgesic and anticonvulsant activity of new derivatives of 2-substituted 4-hydroxybutanamides in mice

Analgesic, anticonvulsant and antioxidant activities of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one dihydrochloride in mice

Analgesic, antioedematous and antioxidant activity of γ-butyrolactone derivatives in rodents

Antiallodynic and antihyperalgesic activity of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one compared to pregabalin in chemotherapy-induced neuropathic pain in mice.

Antiarrhythmic and α-Adrenoceptor Antagonistic Properties of Novel Arylpiperazine Derivatives of Pyrrolidin-2-one.

Antiarrhythmic properties of phenylpiperazine derivatives of phenytoin with α₁-adrenoceptor affinities

Antidepressant-like activity of the phenylpiperazine pyrrolidin-2-one derivatives in mice.

Application of RP-TLC technique for the determination of dissociation constants of 1-substituted pyrrolidin-2-one derivatives

Application of a Library of Artificial Receptors Formed by Self-Organization ofN-Lipidated Peptides Immobilized on Cellulose for Preliminary Studies of Binding ofN-Phenylpiperazines

Application of a library of artificial receptors formed by the self-organization of N-lipidated peptides immobilized on cellulose in studying the effects of the incorporation of a fluorine atom.

Application of computational methods for the design of BACE-1 inhibitors: validation of in silico modelling.

Biphenylalkoxyamine Derivatives-Histamine H Receptor Ligands with Butyrylcholinesterase Inhibitory Activity

Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands.

Corrigendum to "Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands" [Eur. J. Med. Chem. 185 (2020) 111785]

Design, Synthesis and Evaluation of Novel 2-(Aminoalkyl)-isoindoline-1,3-dione Derivatives as Dual-Binding Site Acetylcholinesterase Inhibitors

Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents.

Design, Synthesis, and Biological Evaluation of 2-(Benzylamino-2-Hydroxyalkyl)Isoindoline-1,3-Diones Derivatives as Potential Disease-Modifying Multifunctional Anti-Alzheimer Agents.

Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation

Design, synthesis and pharmacological evaluation of alpha-substituted N-benzylamides of gamma-hydroxybutyric acid with potential GABA-ergic activity. Part 6. Search for new anticonvulsant compounds.

Design, synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxy-propyl]-3,3-diphenylpyrrolidin-2-one derivatives with antiarrhythmic, antihypertensive, and alpha-adrenolytic activity.

Determination of lipophilicity of alpha-(4-phenylpiperazine) derivatives of N-benzylamides using chromatographic and computational methods

Determination of lipophilicity of γ-butyrolactone derivatives with anticonvulsant and analgesic activity using micellar electrokinetic chromatography

Development of an in-vivo active reversible butyrylcholinesterase inhibitor.

Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and β-amyloid aggregation inhibitors with neuroprotective properties

Development, recent achievements and current directions of research into GABA uptake inhibitors

Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines.

Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives-Anticancer and Cholinesterase-Inhibiting Activity

Dual-acting diether derivatives of piperidine and homopiperidine with histamine H(3) receptor antagonistic and anticholinesterase activity

Electrophoretically mediated microanalysis technique as a tool for the rapid screening of novel acetylcholinesterase inhibitors.

Estimation of phospholipophilicity of 1-[3-(arylpiperazin-1-yl)-propyl]-pyrrolidin-2-one derivatives on immobilized artificial membrane stationary phase and its correlation with biological data

Estimation of the lipophilicity of antiarrhythmic and antihypertensive active 1-substituted pyrrolidin-2-one and pyrrolidine derivatives

Evaluation of anticonvulsant activity of novel pyrrolidin-2-one derivatives

Evaluation of antinociceptive and antioxidant properties of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one in mice

Evaluation of anxiolytic-like, anticonvulsant, antidepressant-like and antinociceptive properties of new 2-substituted 4-hydroxybutanamides with affinity for GABA transporters in mice.

Hybrid approach to structure modeling of the histamine H3 receptor: Multi-level assessment as a tool for model verification

Influence of new gamma-hydroxybutyric acid amide analogues on the central nervous system activity in mice.

Investigation into new anticonvulsant derivatives of alpha-substituted N-benzylamides of gamma-hydroxy- and gamma-acetoxybutyric acid. Part 5: search for new anticonvulsant compounds

Investigation of lipophilicity of anticancer-active thioquinoline derivatives

Isoindoline-1,3-dione derivatives targeting cholinesterases: design, synthesis and biological evaluation of potential anti-Alzheimer's agents

Lipophilic properties of anti-Alzheimer's agents determined by micellar electrokinetic chromatography and reversed-phase thin-layer chromatography.

Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease

Multiple Ligands Targeting Cholinesterases and β-Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore

New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition

New tacrine analogs as acetylcholinesterase inhibitors - theoretical study with chemometric analysis.

Novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties as cholinesterases inhibitors.

Novel application of capillary electrophoresis with a liposome coated capillary for prediction of blood-brain barrier permeability

Novel carbamate derivatives as selective butyrylcholinesterase inhibitors.

Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice

Novel multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease.

Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT6 receptor antagonists. Design, synthesis and biological evaluation.

Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer's disease

Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease.

Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment

SEARCH FOR POTENTIAL CHOLINESTERASE INHIBITORS FROM THE ZINC DATABASE BY VIRTUAL SCREENING METHOD.

Search for anticonvulsant and analgesic active derivatives of dihydrofuran-2(3H)-one

Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives

Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands

Search for new potential anticonvulsants with anxiolytic and antidepressant properties among derivatives of 4,4-diphenylpyrrolidin-2-one

Stereocontrolled synthesis of the enantiomers of 1-[2-hydroxy-3-(4-phenyl-1-piperazinyl)-propyl]-pyrrolidin-2-one

Structure-Activity Relationship Studies of a Number of α1 -Adrenoceptor Antagonists and Antiarrhythmic Agents.

Structure-based search for new inhibitors of cholinesterases.

Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy.

Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease.

Synthesis and biological evaluation of new derivatives of 2-substituted 4-hydroxybutanamides as GABA uptake inhibitors

Synthesis and development of new 2-substituted 1-[3-(4-arylpiperazin-1-yl)propyl]-pyrrolidin-2-one derivatives with antiarrhythmic, hypotensive, and alpha-adrenolytic activity

Synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxypropyl]-pyrrolidin-2-one derivatives with anti-arrhythmic, hypotensive, and alpha-adrenolytic activity

Synthesis and pharmacological evaluation of new 1-[3-(4-phenylpiperazin-1-yl)-propyl]- and 1-[3-(4-phenylpiperidine)-propyl]- 3-aryl-3-alkyl-pyrrolidin-2-one derivatives with antiarrhythmic and antihypertensive activity

Synthesis and pharmacological evaluation of pyrrolidin-2-one derivatives as antiarrhythmic, antihypertensive and alpha-adrenolytic agents

Synthesis and pharmacological properties of new GABA uptake inhibitors.

Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo

Synthesis of novel N-alkyl carbamates of a-substituted amides of g-hydroxybutyric acid as potential acetylcholinesterase inhibitors

Synthesis of novel N-benzyl substituted piperidine amides of 1H-indole-5-carboxylic acid as potential inhibitors of cholinesterases.

Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta.

Synthesis, antiarrhythmic, and antihypertensive effects of novel 1-substituted pyrrolidin-2-one and pyrrolidine derivatives with adrenolytic activity.