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List of works by Chih-Yang Huang

17β-Estradiol and/or estrogen receptor alpha blocks isoproterenol-induced calcium accumulation and hypertrophy via GSK3β/PP2A/NFAT3/ANP pathway.

scientific article published on 2 June 2017

17β-Estradiol and/or estrogen receptor alpha signaling blocks protein phosphatase 1 mediated ISO induced cardiac hypertrophy.

scientific article

A minireview of E4BP4/NFIL3 in heart failure

scientific article published on 01 June 2018

Acute hypoxic preconditioning prevents palmitic acid-induced cardiomyocyte apoptosis via switching metabolic GLUT4-glucose pathway back to CD36-fatty acid dependent

scientific article published on 11 November 2017

Adipose-derived stem cells decrease cardiomyocyte damage induced by porphyromonas gingivalis endotoxin through suppressing hypertrophy, apoptosis, fibrosis, and MAPK markers.

scientific article published on 31 January 2018

Alpinate Oxyphyllae Fructus (Alpinia Oxyphylla Miq) Extracts Inhibit Angiotensin-II Induced Cardiac Apoptosis in H9c2 Cardiomyoblast Cells

scientific article published on February 7, 2013

Alpinate Oxyphyllae extracts enhance the longevity and homing of mesenchymal stem cells and augment their protection against senescence in H9c2 cells

scientific article published on 04 December 2018

Alpinia oxyphylla Miq extract ameliorates cardiac fibrosis associated with D-galactose induced aging in rats

scientific article published on 27 October 2018

Andrographolide mitigates cardiac apoptosis to provide cardio-protection in high-fat-diet-induced obese mice

scientific article published on 05 February 2020

Anti-Inflammatory Effects of Probiotic Lactobacillus paracasi on Ventricles of BALB/C Mice Treated with Ovalbumin

scientific article published on February 29, 2012

Beneficial Effects ofOcimum gratissimumAqueous Extract on Rats with CCl4-Induced Acute Liver Injury ⬇️

scientific article published on June 27, 2012

Bioactive Peptide VHVV Upregulates the Long-Term Memory-Related Biomarkers in Adult Spontaneously Hypertensive Rats

scientific article published on 23 June 2019

Bioactive peptides attenuate cardiac apoptosis in spontaneously hypertensive rat hearts through activation of autophagy and mitochondrial biogenesis pathway

scientific article published on 05 March 2020

Bioactive peptides attenuate cardiac hypertrophy and fibrosis in spontaneously hypertensive rat hearts

scientific article published on 28 November 2019

CCN6 enhances ICAM‐1 expression and cell motility in human chondrosarcoma cells ⬇️

scientific article published on January 1, 2012

CHIP attenuates lipopolysaccharide-induced cardiac hypertrophy and apoptosis by promoting NFATc3 proteasomal degradation

scientific article published on 13 April 2019

CXCL2/CXCR2 axis induces cancer stem cell characteristics in CPT-11-resistant LoVo colon cancer cells via Gαi-2 and Gαq/11

scientific article published on 14 December 2018

Cardiac Injury Protection from Mouse Bone Marrow Stromal Cells with In Utero Transplantation Followed by Secondary Postnatal Boost

scientific article published on August 31, 2011

Carthamus tinctorius L. extract activates insulin-like growth factor-I receptor signaling to inhibit FAS-death receptor pathway and suppress lipopolysaccharides-induced H9c2 cardiomyoblast cell apoptosis

scientific article published on 04 September 2019

Chemoresistance-Associated Silencing of miR-4454 Promotes Colorectal Cancer Aggression through the GNL3L and NF-κB Pathway

scientific article published on 14 May 2020

Correction: Liu, Y.-S.; et al. Inhibition of Protein Phosphatase 1 Stimulates Noncanonical ER Stress eIF2α Activation to Enhance Fisetin-Induced Chemosensitivity in HDAC Inhibitor-Resistant Hepatocellular Carcinoma Cells. Cancers 2019, 11, 918

scientific article published on 03 November 2020

Cryptotanshinone (Dsh-003) from Salvia miltiorrhiza Bunge inhibits prostaglandin E2-induced survival and invasion effects in HA22T hepatocellular carcinoma cells

scientific article published on 12 September 2018

D-galactose-induced toxicity associated senescence mitigated by alpinate oxyphyllae fructus fortified adipose-derived mesenchymal stem cells

scientific article published on 05 September 2020

Danshen (Salvia miltiorhiza) inhibits Leu27 IGF-II-induced hypertrophy in H9c2 cells

scientific article published on 16 May 2020

Danshen mediates through estrogen receptors to activate Akt and inhibit apoptosis effect of Leu27IGF-II-induced IGF-II receptor signaling activation in cardiomyoblasts ⬇️

scientific article published on February 16, 2013

Deep ocean mineral water accelerates recovery from physical fatigue ⬇️

scientific article published on February 12, 2013

Deep sea minerals ameliorate diabetic-induced inflammation via inhibition of TNFα signaling pathways

scientific article published on 03 December 2019

Diallyl Trisulfide (DATS) Suppresses AGE-Induced Cardiomyocyte Apoptosis by Targeting ROS-Mediated PKCδ Activation

scientific article published on 09 April 2020

Dietary oxidised frying oil causes oxidative damage of pancreatic islets and impairment of insulin secretion, effects associated with vitamin E deficiency ⬇️

scientific article published on December 16, 2010

Dilong: Role in Peripheral Nerve Regeneration ⬇️

scientific article published on June 15, 2011

Dipeptide IF prevents the effects of hypertension-induced Alzheimer's disease on long-term memory in the cortex of spontaneously hypertensive rats

scientific article published on 30 December 2019

E2/ER β inhibit ISO-induced cardiac cellular hypertrophy by suppressing Ca2+-calcineurin signaling.

scientific article published on September 2017

ERβ targets ZAK and attenuates cellular hypertrophy via SUMO-1 modification in H9c2 cells

scientific article published on 22 June 2018

Earthworms Dilong: Ancient, Inexpensive, Noncontroversial Models May Help Clarify Approaches to Integrated Medicine Emphasizing Neuroimmune Systems ⬇️

scientific article published on July 25, 2012

Effect of Vasicinone against Paraquat-Induced MAPK/p53-Mediated Apoptosis via the IGF-1R/PI3K/AKT Pathway in a Parkinson's Disease-Associated SH-SY5Y Cell Model

scientific article published on 19 July 2019

Endothelin-1 enhances cell migration through COX-2 up-regulation in human chondrosarcoma ⬇️

scientific article published on March 21, 2013

Endothelin-1 promotes vascular endothelial growth factor-dependent angiogenesis in human chondrosarcoma cells ⬇️

scientific article published on April 15, 2013

Eriobotrya japonica ameliorates cardiac hypertrophy in H9c2 cardiomyoblast and in spontaneously hypertensive rats

scientific article published on 04 July 2018

Extracts of Jasminum sambac flowers fermented by Lactobacillus rhamnosus inhibit H<sub>2</sub> O<sub>2</sub> - and UVB-induced aging in human dermal fibroblasts

scientific article published on 03 December 2020

FOXC1 Regulation of miR-31-5p Confers Oxaliplatin Resistance by Targeting LATS2 in Colorectal Cancer

scientific article published on 16 October 2019

Fisetin activates Hippo pathway and JNK/ERK/AP-1 signaling to inhibit proliferation and induce apoptosis of human osteosarcoma cells via ZAK overexpression

scientific article published on 01 May 2019

Fisetin mediated apoptotic cell death in parental and Oxaliplatin/irinotecan resistant colorectal cancer cells in vitro and in vivo.

scientific article published on 25 March 2018

Functional potato bioactive peptide intensifies Nrf2-dependent antioxidant defense against renal damage in hypertensive rats

scientific article published on 03 December 2019

GABA tea attenuates cardiac apoptosis in spontaneously hypertensive rats (SHR) by enhancing PI3K/Akt-mediated survival pathway and suppressing Bax/Bak dependent apoptotic pathway

scientific article published on 30 April 2018

Growth-Promoting Effects of Quercetin on Peripheral Nerves in Rats ⬇️

scientific article published on 01 November 2011

H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis

scientific article

HMGB1 promotes ERK-mediated mitochondrial Drp1 phosphorylation for chemoresistance through RAGE in colorectal cancer

scientific article published on 26 September 2018

Heat-Killed Lactobacillus reuteri GMNL-263 Inhibits Systemic Lupus Erythematosus-Induced Cardiomyopathy in NZB/W F1 Mice

scientific article published on 08 June 2020

Herbal Supplement Ameliorates Cardiac Hypertrophy in Rats with CCl4-Induced Liver Cirrhosis ⬇️

scientific article published on November 6, 2012

High density lipoprotein (HDL) reverses palmitic acid induced energy metabolism imbalance by switching CD36 and GLUT4 signaling pathways in cardiomyocyte.

scientific article published on 13 May 2017

Histone acetylation is essential for ANG‐II‐induced IGF‐IIR gene expression in H9c2 cardiomyoblast cells and pathologically hypertensive rat heart ⬇️

scientific article published on January 1, 2012

Identification of an Autoantibody against the Proliferating Cell Nuclear Antigen from a Patient with Systemic Lupus Erythematosus

scientific article published on February 28, 2010

Illuminating the Molecular Intricacies of Exosomes and ncRNAs in Cardiovascular Diseases: Prospective Therapeutic and Biomarker Potential

scientific article published in 2022

Inhibition of Cardiac Hypertrophy Effects in D-Galactose-Induced Senescent Hearts by Alpinate Oxyphyllae Fructus Treatment

scientific article

Inhibition of cardiac hypertrophy by probiotic-fermented purple sweet potato yogurt in spontaneously hypertensive rat hearts ⬇️

scientific article published on October 12, 2012

Inhibitory effects of Rhenium-188-labeled Herceptin on prostate cancer cell growth: A possible radioimmunotherapy to prostate carcinoma ⬇️

scientific article published on February 27, 2013

LPS-enhanced IGF-IIR pathway to induce H9c2 cardiomyoblast cell hypertrophy was attenuated by Carthamus tinctorius extract via IGF-IR activation

scientific article published on 12 November 2019

Lactobacillus paracasei GMNL-32 exerts a therapeutic effect on cardiac abnormalities in NZB/W F1 mice.

scientific article published on 21 September 2017

Lower tumorigenesis without life extension in rats receiving lifelong deep ocean minerals

scientific article published on 03 April 2020

Lupeol alters ER stress-signaling pathway by downregulating ABCG2 expression to induce Oxaliplatin-resistant LoVo colorectal cancer cell apoptosis.

scientific article published on 13 February 2018

Mesenchymal Stem Cell Insights: Prospects in Hematological Transplantation ⬇️

scientific article published on November 27, 2012

Mitochondrial ROS-induced ERK1/2 activation and HSF2-mediated AT1 R upregulation are required for doxorubicin-induced cardiotoxicity.

scientific article published on 14 March 2017

Neferine modulates IGF-1R/Nrf2 signaling in doxorubicin treated H9c2 cardiomyoblasts

scientific article

Neferine suppresses diethylnitrosamine-induced lung carcinogenesis in Wistar rats

scientific article published on 10 November 2018

Oral administration of alcalase potato protein hydrolysate-APPH attenuates high fat diet-induced cardiac complications via TGF-β/GSN axis in aging rats

scientific article published on 21 September 2018

Overexpression of IGF-IIRα regulates cardiac remodeling and aggravates high salt induced apoptosis and fibrosis in transgenic rats

scientific article published on 18 November 2018

Overexpression of ZAKβ in human osteosarcoma cells enhances ZAKα expression, resulting in a synergistic apoptotic effect

scientific article published on 13 April 2018

Oxaliplatin resistance in colorectal cancer cells is mediated via activation of ABCG2 to alleviate ER stress induced apoptosis

scientific article

Pheretima aspergillum extract attenuates high-KCl-induced mitochondrial injury and pro-fibrotic events in cardiomyoblast cells

scientific article published on 07 May 2019

Poria cocos (Fuling) targets TGFβ/Smad7 associated collagen accumulation and enhances Nrf2-antioxidant mechanism to exert anti-skin aging effects in human dermal fibroblasts

scientific article published on 18 December 2020

Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis.

scientific article

Protective effect of autologous transplantation of resveratrol preconditioned adipose-derived stem cells in the treatment of diabetic liver dysfunction in rat model

scientific article published on 01 August 2019

Protective effects of galangin against H2 O2 -induced aging via the IGF-1 signaling pathway in human dermal fibroblasts

scientific article published on 30 September 2019

Protein Kinase C Alpha Location and the Expression of Phospho-MEK and MDR1 in Hepatitis Virus-Related Hepatocellular Carcinoma Biopsies

scientific article published on April 30, 2010

Protein supplementation enhances cerebral oxygenation during exercise in elite basketball players

scientific article published on 05 February 2018

Pro‐inflammation and pro‐fibrosis factors were highly induction in heart tissues of carotid arteries balloon‐injured animal model ⬇️

scientific article published on March 13, 2012

Pulse Analysis in Bipolar Disordered and Nonpsychotic Human Subjects ⬇️

scientific article published on January 1, 2012

RANKL increases migration of human lung cancer cells through intercellular adhesion molecule-1 up-regulation

scientific article published on March 1, 2011

ROS- and HIF1α-dependent IGFBP3 upregulation blocks IGF1 survival signaling and thereby mediates high-glucose-induced cardiomyocyte apoptosis

scientific article published on 19 January 2019

Rab9-dependent autophagy is required for the IGF-IIR triggering mitophagy to eliminate damaged mitochondria.

scientific article published on 25 March 2018

Ramipril and resveratrol co-treatment attenuates RhoA/ROCK pathway-regulated early-stage diabetic nephropathy-associated glomerulosclerosis in streptozotocin-induced diabetic rats

scientific article published on 07 May 2019

Resistin protects against 6‐hydroxydopamine‐induced cell death in dopaminergic‐like MES23.5 cells ⬇️

scientific article published on March 1, 2013

Resveratrol increases stem cell function in the treatment of damaged pancreas

scientific article published on 29 April 2019

Retinoic Acid Induces Apoptosis of Prostate Cancer DU145 Cells through Cdk5 Overactivation ⬇️

scientific article published on December 13, 2012

Rhubarb inhibits hepatocellular carcinoma cell metastasis via GSK-3-β activation to enhance protein degradation and attenuate nuclear translocation of β-catenin ⬇️

scientific article published on November 8, 2012

Role of potato protein hydrolysate and exercise in preventing high-fat diet-induced hepatocyte apoptosis in senescence-accelerated mouse

scientific article published on 19 October 2020

Seven traditional Chinese herbal extracts fermented by Lactobacillus rhamnosus provide anti-pigmentation effects by regulating the CREB/MITF/tyrosinase pathway

scientific article published on 14 December 2020

Short-Term Hypoxia Reverses Ox-LDL-Induced CD36 and GLUT4 Switching Metabolic Pathways in H9c2 Cardiomyoblast Cells

scientific article published on 4 April 2017

Short-term hypoxia upregulated Mas receptor expression to repress the AT1 R signaling pathway and attenuate Ang II-induced cardiomyocyte apoptosis

scientific article published on 20 October 2017

Signal transducer and activator of transcription 3 mediates apoptosis inhibition through reducing mitochondrial ROS and activating Bcl-2 in gemcitabine-resistant lung cancer A549 cells

scientific article published on 07 December 2020

Significant Association of Caveolin-1 Genotypes with Bladder Cancer Susceptibility in Taiwan

scientific article published on June 30, 2011

Significant Association of XPD Asp312Asn Polymorphism with Breast Cancer in Taiwanese Patients

scientific article published on April 30, 2010

Stem cells rescue cardiomyopathy induced by P. gingivalis-LPS via miR-181b.

scientific article published on 11 December 2017

Synergistic cardiac pathological hypertrophy induced by high-salt diet in IGF-IIRα cardiac-specific transgenic rats

scientific article published on 18 June 2019

Synergistic effect of HIF-1α and FoxO3a trigger cardiomyocyte apoptosis under hyperglycemic ischemia condition

scientific article published on 14 October 2017

Taiwanin C elicits apoptosis in arecoline and 4-nitroquinoline-1-oxide-induced oral squamous cell carcinoma cells and hinders proliferation via epidermal growth factor receptor/PI3K suppression

scientific article published on 18 March 2019

The combined inhibition of the CaMKIIδ and calcineurin signaling cascade attenuates IGF-IIR-induced cardiac hypertrophy

scientific article published on 04 October 2019

The multifaceted link between inflammation and human diseases.

scientific article published on 11 January 2018

Tid1, CHIP and ErbB2 interactions and their prognostic implications for breast cancer patients ⬇️

scientific article published on June 27, 2011

Tid1-S attenuates LPS-induced cardiac hypertrophy and apoptosis through ER-a mediated modulation of p-PI3K/p-Akt signaling cascade

scientific article published on 13 May 2019

Upregulation of IGF-IIRα intensifies doxorubicin-induced cardiac damage

scientific article published on 19 May 2019

Zanthoxylum avicennae extracts inhibit cell proliferation through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma cells in vitro and in vivo ⬇️

scientific article published on March 13, 2012

p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure.

scientific article published on 10 August 2017

β-catenin plays a key role in metastasis of human hepatocellular carcinoma ⬇️

scientific article published on May 26, 2011

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