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List of works by Stefan Sleijfer

(Pre-)clinical pharmacology and activity of pazopanib, a novel multikinase angiogenesis inhibitor

scientific article

A new approach for rapid and reliable enumeration of circulating endothelial cells in patients.

scientific article

A phase I study on the combination of neoadjuvant radiotherapy plus pazopanib in patients with locally advanced soft tissue sarcoma of the extremities

scientific article published on 29 April 2015

A randomized phase 2 study exploring the role of bevacizumab and a chemotherapy-free approach in HER2-positive metastatic breast cancer: The HAT study (BOOG 2008-2003), a Dutch Breast Cancer Research Group trial.

scientific article published on 17 June 2016

AR splice variants in circulating tumor cells of patients with castration-resistant prostate cancer: relation with outcome to cabazitaxel

scientific article published on 28 June 2019

Abstract 4433: Deregulated microRNAs in NF1 derived malignant peripheral nerve sheath tumors (MPNST) and their role in carcinogenesis

Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review.

scientific article published on 17 May 2019

Active surveillance in desmoid-type fibromatosis: A systematic literature review

scientific article published on 29 July 2020

Adoptive immuno-gene therapy of cancer with single chain antibody [scFv(Ig)] gene modified T lymphocytes.

scientific article published in April 2004

Allele-Specific, Non-Extendable Primer Blocker PCR (AS-NEPB-PCR) for DNA Mutation Detection in Cancer ⬇️

scientific article published on November 14, 2012

Alternating Treatment With Pazopanib and Everolimus vs Continuous Pazopanib to Delay Disease Progression in Patients With Metastatic Clear Cell Renal Cell Cancer: The ROPETAR Randomized Clinical Trial

scientific article published on December 2016

An 8-gene mRNA expression profile in circulating tumor cells predicts response to aromatase inhibitors in metastatic breast cancer patients

scientific article published on 18 February 2016

An In-Depth Evaluation of the Validity and Logistics Surrounding the Testing of AR-V7 mRNA Expression in Circulating Tumor Cells

scientific article

An optimized workflow to evaluate estrogen receptor gene mutations in small amounts of cell-free DNA

article

Anaplastic lymphoma kinase aberrations in rhabdomyosarcoma: clinical and prognostic implications.

scientific article published on 19 December 2011

Androgen receptor expression in circulating tumor cells of patients with metastatic breast cancer

scientific article published on 27 February 2019

Angiogenesis inhibition in non-GIST soft tissue sarcomas

scientific article

Anti-epithelial cell adhesion molecule antibodies and the detection of circulating normal-like breast tumor cells.

scientific article published on 30 December 2008

Application of circulating tumor DNA in prospective clinical oncology trials - standardization of preanalytical conditions.

scientific article

Application of prolonged microdialysis sampling in carboplatin-treated cancer patients

scientific article published on 20 December 2008

Are immune signatures a worthwhile tool for decision making in early-stage human epidermal growth factor receptor 2-positive breast cancer?

scientific article published on 20 January 2015

Assessing the Desmoid-Type Fibromatosis Patients' Voice: Comparison of Health-Related Quality of Life Experiences from Patients of Two Countries

scientific article published on 26 July 2020

Association between single-nucleotide polymorphisms and adverse events in nivolumab-treated non-small cell lung cancer patients

scientific article published on 26 April 2018

Association of an extracellular matrix gene cluster with breast cancer prognosis and endocrine therapy response

scientific article

Association of pazopanib-induced toxicities with outcome of patients with advanced soft tissue sarcoma; a retrospective analysis based on the European Organisation for Research and Treatment of Cancer (EORTC) 62043 and 62072 clinical trials

scientific article published on 04 March 2019

Associations between AR-V7 status in circulating tumour cells, circulating tumour cell count and survival in men with metastatic castration-resistant prostate cancer

scientific article published on 19 September 2019

Biliary excretion of imatinib and its active metabolite CGP74588 during severe hepatic dysfunction

scientific article

Bioanalytical method for the quantification of sunitinib and its n-desethyl metabolite SU12662 in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry

scientific article

Bleomycin and scuba diving: where is the harm?

scientific article published on 01 November 2007

Bridging the Translational Divide in Oncology: In Vivo Testing of Chemo-Sensitivity

scientific article published on 01 June 2020

CD49f-based selection of circulating tumor cells (CTCs) improves detection across breast cancer subtypes ⬇️

scientific article published on December 24, 2011

Can docetaxel plus estramustine prolong survival of men with metastatic hormone-refractory prostate cancer?

scientific article published in February 2005

Cancer Clinical Trials—Do We Need a New Algorithm in the Age of Stratified Medicine? ⬇️

scientific article published on June 1, 2013

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen

scientific article

Cells meeting our immunophenotypic criteria of endothelial cells are large platelets

scientific article

Central venous access related adverse events after trabectedin infusions in soft tissue sarcoma patients; experience and management in a nationwide multi-center study

scientific article published on 31 January 2017

Changes in body composition and muscle attenuation during taxane-based chemotherapy in patients with metastatic breast cancer

scientific article published on 17 November 2017

Chemotherapy: Adjuvant chemotherapy in older patients with breast cancer

scientific article published in October 2009

Circulating Tumor Cell Enumeration and Characterization in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Cabazitaxel

scientific article published on 20 August 2019

Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-analysis.

scientific article published on 12 April 2018

Circulating endothelial cell enumeration demonstrates prolonged endothelial damage in recipients of myeloablative allogeneic stem cell transplantation.

scientific article published on 20 February 2015

Circulating endothelial cells in oncology: pitfalls and promises

scientific article published on 27 May 2008

Circulating endothelial cells, circulating tumour cells, tissue factor, endothelin-1 and overall survival in prostate cancer patients treated with docetaxel

scientific article published in July 2010

Circulating endothelial cells: a potential parameter of organ damage in sickle cell anemia?

scientific article published on 7 April 2009

Circulating tumor cell enumeration by the CellSearch system: the clinician's guide to breast cancer treatment?

scientific article published on 23 December 2014

Circulating tumor cell isolation and diagnostics: toward routine clinical use

scientific article published on 06 September 2011

Circulating tumor cells (CTCs): detection methods and their clinical relevance in breast cancer

scientific article published on May 2009

Circulating tumor cells and sample size: the more, the better.

scientific article published on 3 May 2010

Circulating tumor cells and survival in abiraterone- and enzalutamide-treated patients with castration-resistant prostate cancer

scientific article published on 12 February 2018

Circulating tumor cells, tumor-derived extracellular vesicles and plasma cytokeratins in castration-resistant prostate cancer patients

scientific article published on 10 April 2018

Circulating tumour cell detection on its way to routine diagnostic implementation?

scientific article

Clinical value of circulating endothelial cell detection in oncology.

scientific article

Comparison of variant allele frequency and number of mutant molecules as units of measurement for circulating tumor DNA

scientific article published on 18 October 2020

Controversies in the Management of Clinical Stage I Seminoma: Carboplatin a Decade in-Time to Start Backing Out.

scientific article published in February 2018

Correction: Tumor Volume as an Alternative Response Measurement for Imatinib Treated GIST Patients

Correlation between circulating endothelial cell counts and plasma thrombomodulin levels as markers for endothelial damage.

scientific article

Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes ⬇️

scientific article published on July 12, 2011

Current clinical trials for advanced osteosarcoma and soft tissue sarcoma

scientific article published on July 2014

Decrease of CD117 expression as possible prognostic marker for recurrence in the resected specimen after imatinib treatment in patients with initially unresectable gastrointestinal stromal tumors: a clinicopathological analysis

scientific article

Defining the dimensions of Circulating Tumor Cells in a large series of breast, prostate, colon, and bladder cancer patients ⬇️

scientific article published on 18 September 2020

Denosumab in breast cancer treatment ⬇️

scientific article published on March 29, 2013

Deregulated microRNAs in neurofibromatosis type 1 derived malignant peripheral nerve sheath tumors

scientific article published on 19 February 2020

Designing Transformative Clinical Trials in the Cancer Genome Era ⬇️

scientific article published on April 15, 2013

Detection of circulating tumor cells in breast cancer may improve through enrichment with anti-CD146.

scientific article

Development and validation of an UPLC-MS/MS method for the quantification of tamoxifen and its main metabolites in human scalp hair

scientific article published on 12 June 2015

Diagnostic and therapeutic ionizing radiation and the risk of a first and second primary breast cancer, with special attention for BRCA1 and BRCA2 mutation carriers: a critical review of the literature

scientific article published on 08 December 2014

Diagnostic applications of cell-free and circulating tumor cell-associated miRNAs in cancer patients

scientific article

Differential diagnosis and mutation stratification of desmoid-type fibromatosis on MRI using radiomics

scientific article published on 08 September 2020

Differentially Methylated Regions in Desmoid-Type Fibromatosis: A Comparison Between CTNNB1 S45F and T41A Tumors

scientific article published on 29 October 2020

Dose selection in phase I studies: why we should always go for the top

scientific article published on 10 March 2008

Downregulation of SIAH2, an ubiquitin E3 ligase, is associated with resistance to endocrine therapy in breast cancer

scientific article published on 16 July 2008

Drug Insight: gastrointestinal stromal tumors (GIST)--the solid tumor model for cancer-specific treatment

scientific article published on February 2008

ESR1 mutations: Moving towards guiding treatment decision-making in metastatic breast cancer patients

scientific article

Editorial: the long and winding road to better cancer cell-specific therapies

scientific article published on 01 May 2008

Effects of Mannose-Binding Lectin Polymorphisms on Irinotecan-Induced Febrile Neutropenia ⬇️

scientific article published on October 7, 2010

Efficacy of Cabazitaxel in Castration-resistant Prostate Cancer Is Independent of the Presence of AR-V7 in Circulating Tumor Cells

scientific article published on 15 July 2015

Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients

scientific article published on 24 October 2017

Evidence on the cost of breast cancer drugs is required for rational decision making.

scientific article

Expression and inhibition of BRD4, EZH2 and TOP2A in neurofibromas and malignant peripheral nerve sheath tumors.

scientific article

External quality assurance of circulating tumor cell enumeration using the CellSearch® system: A feasibility study

article

First-Line Palliative HER2-Targeted Therapy in HER2-Positive Metastatic Breast Cancer Is Less Effective After Previous Adjuvant Trastuzumab-Based Therapy

scientific article published on 22 May 2017

GIST as the model of paradigm shift towards targeted therapy of solid tumors: update and perspective on trial design

scientific article

Gastrointestinal stromal tumors II: medical oncology and tumor response assessment

scientific article published on August 2009

Gene expression profiles of circulating tumor cells versus primary tumors in metastatic breast cancer.

scientific article published on 19 March 2015

Gene-modified T cells for adoptive immunotherapy of renal cell cancer maintain transgene-specific immune functions in vivo

scientific article

Genetic polymorphisms in ABCG2 and CYP1A2 are associated with imatinib dose reduction in patients treated for gastrointestinal stromal tumors

scientific article published on 04 February 2019

Genetic polymorphisms in angiogenesis-related genes are associated with worse progression-free survival of patients with advanced gastrointestinal stromal tumours treated with imatinib.

scientific article

Gynaecological sarcomas

scientific article

Health policy: Affordability of drugs used in oncology health care

scientific article published on 10 May 2016

High ctDNA molecule numbers relate with poor outcome in advanced ER+, HER2- postmenopausal breast cancer patients treated with everolimus and exemestane

scientific article published on 07 February 2020

High-throughput isolation of circulating tumor DNA: a comparison of automated platforms

scientific article published on 22 December 2018

Hotspot mutations in PIK3CA associate with first-line treatment outcome for aromatase inhibitors but not for tamoxifen ⬇️

scientific article published on April 17, 2013

How to decide whether to offer and use "nonstandard" therapies in patients with advanced sarcomas and gastrointestinal stromal tumors: global variations in clinical practice, assessment, and access to therapies in diseases with limited incidence and

scientific article

Identification and assessment of health-related quality of life issues in patients with sporadic desmoid-type fibromatosis: a literature review and focus group study

scientific article published on 16 July 2018

Identification of microRNA biomarkers for response of advanced soft tissue sarcomas to eribulin: Translational results of the EORTC 62052 trial

scientific article published on 16 February 2017

Imatinib-induced agranulocytosis in patients with gastrointestinal stromal tumors.

scientific article

Immune responses to transgene and retroviral vector in patients treated with ex vivo–engineered T cells ⬇️

scientific article published on January 6, 2011

Impact of CYP3A4*22 on Pazopanib Pharmacokinetics in Cancer Patients

scientific article published on 01 May 2019

Impact of Concomitant Administration of Gastric Acid-Suppressive Agents and Pazopanib on Outcomes in Soft-Tissue Sarcoma Patients Treated within the EORTC 62043/62072 Trials

scientific article published on 14 February 2019

Impact of panel design and cut-off on tumour mutational burden assessment in metastatic solid tumour samples

scientific article published on 25 February 2020

Improved Circulating Tumor Cell Detection by a Combined EpCAM and MCAM CellSearch Enrichment Approach in Patients with Breast Cancer Undergoing Neoadjuvant Chemotherapy

scientific article published on 31 December 2014

Improved diagnosis and prognostication of patients with pleural malignant mesothelioma using biomarkers in pleural effusions and peripheral blood samples - a short report.

scientific article published on 2 June 2017

Improved insight into resistance mechanisms to imatinib in gastrointestinal stromal tumors: a basis for novel approaches and individualization of treatment

scientific article

Incorporating liquid biopsies into treatment decision-making: obstacles and possibilities

scientific article published on 03 June 2019

Increasing tumoral 5-fluorouracil concentrations during a 5-day continuous infusion: a microdialysis study

scientific article

Inflammation and fatigue dimensions in advanced cancer patients and cancer survivors ⬇️

scientific article published on June 26, 2012

Interferon-alpha in oncology patients: fewer psychiatric side effects than anticipated

scientific article published on 01 January 2008

Interferon-alpha influences tryptophan metabolism without inducing psychiatric side effects

scientific article published on 17 September 2007

International expert opinion on patient-tailored management of soft tissue sarcomas

scientific article

International study on inter-reader variability for circulating tumor cells in breast cancer

scientific article

Irinotecan-induced central nervous system toxicity. Report on two cases and review of the literature

scientific article published in January 2008

It takes two to tango: combinations of conventional cytotoxics with compounds targeting the vascular endothelial growth factor-vascular endothelial growth factor receptor pathway in patients with solid malignancies

scientific article

KRAS and BRAF mutation status in circulating colorectal tumor cells and their correlation with primary and metastatic tumor tissue ⬇️

scientific article published on February 9, 2013

Liquid Biopsies to Select Patients for Perioperative Chemotherapy in Muscle-invasive Bladder Cancer: A Systematic Review

scientific article published on 11 February 2020

Long-term stability of T-cell activation and transduction components critical to the processing of clinical batches of gene-engineered T cells ⬇️

scientific article published on February 4, 2013

Low Tumor Mitochondrial DNA Content Is Associated with Better Outcome in Breast Cancer Patients Receiving Anthracycline-Based Chemotherapy

scientific article published on 18 April 2017

Low muscle attenuation is a prognostic factor for survival in metastatic breast cancer patients treated with first line palliative chemotherapy

scientific article

Lysosomal Sequestration Determines Intracellular Imatinib Levels

scientific article

Macrocytosis as a potential parameter associated with survival after tyrosine kinase inhibitor treatment.

scientific article published on 31 January 2016

Mapatumumab, a fully human agonistic monoclonal antibody that targets TRAIL-R1, in combination with gemcitabine and cisplatin: a phase I study.

scientific article

Medical oncology: clinical value of circulating tumor cells in breast cancer

scientific article published on 01 November 2011

MicroRNA expression and DNA methylation profiles do not distinguish between primary and recurrent well-differentiated liposarcoma

scientific article published on 23 January 2020

MicroRNA expression profiles distinguish liposarcoma subtypes and implicate miR-145 and miR-451 as tumor suppressors.

scientific article published on 16 January 2014

MicroRNA response to hypoxic stress in soft tissue sarcoma cells: microRNA mediated regulation of HIF3α

scientific article

MicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer

scientific article published on 19 May 2010

Minimal Increase in Survival Throughout the Years in Patients with Soft Tissue Sarcoma with Synchronous Metastases: Results of a Population-Based Study

scientific article published on 06 September 2018

Mitochondrial DNA content in breast cancer: Impact on in vitro and in vivo phenotype and patient prognosis

scientific article published on 11 April 2016

Mitochondrial RNA Expression and Single Nucleotide Variants in Association with Clinical Parameters in Primary Breast Cancers

scientific article published on 09 December 2018

Molecular Comparison of Imatinib-Naïve and Resistant Gastrointestinal Stromal Tumors: Differentially Expressed microRNAs and mRNAs

scientific article published on 24 June 2019

Molecular characteristics of circulating tumor cells resemble the liver metastasis more closely than the primary tumor in metastatic colorectal cancer

scientific article published on 20 June 2016

Molecular characterization of circulating tumor cells in large quantities of contaminating leukocytes by a multiplex real-time PCR

scientific article published on 30 December 2008

Moving molecular targeted drug therapy towards personalized medicine: Issues related to clinical trial design ⬇️

scientific article published on February 16, 2012

Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Res

scientific article

Natural history of well-differentiated liposarcoma of the extremity compared to patients treated with surgery

scientific article published on 09 April 2019

Neoadjuvant imatinib in locally advanced gastrointestinal stromal tumors (GIST): the EORTC STBSG experience

scientific article published on 13 June 2013

Neurotoxic and neuroprotective metabolites of kynurenine in patients with renal cell carcinoma treated with interferon-alpha: course and relationship with psychiatric status

scientific article

Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy

scientific article published on 26 October 2008

Non-Coding RNAs, a Novel Paradigm for the Management of Gastrointestinal Stromal Tumors

scientific article published on 22 September 2020

Non-islet-cell tumor induced hypoglycemia in patients with advanced gastrointestinal stromal tumor possibly worsened by imatinib

scientific article published on 01 June 2006

Novel methods to diagnose leptomeningeal metastases in breast cancer

scientific article published on 01 March 2019

On the origin of (CD105+) circulating endothelial cells

scientific article

Pan-cancer whole-genome analyses of metastatic solid tumours

scientific article published on 23 October 2019

Patterns and incidence of chromosomal instability and their prognostic relevance in breast cancer subtypes.

scientific article published on 15 July 2010

Pazopanib in advanced desmoplastic small round cell tumours: a multi-institutional experience

scientific article published on 29 July 2014

Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC stu

scientific article

Pazopanib, a new therapy for metastatic soft tissue sarcoma ⬇️

scientific article published on March 14, 2013

Phase I study of cisplatin, hyperthermia, and lapatinib in patients with recurrent carcinoma of the uterine cervix in a previously irradiated area

scientific article

Platelet MAO activity during treatment with pegylated interferon-alfa in melanoma patients

scientific article published on 18 November 2004

Potential biomarkers in metastatic gastrointestinal stromal tumors.

scientific article published in October 2007

Practical aspects of managing gastrointestinal stromal tumors.

scientific article

Pre- and Postoperative Chemotherapy in Localized Extremity Soft Tissue Sarcoma: A European Organization for Research and Treatment of Cancer Expert Survey.

scientific article published on 30 November 2017

Predictors for doxorubicin-induced hematological toxicity and its association with outcome in advanced soft tissue sarcoma patients; a retrospective analysis of the EORTC-soft tissue and bone sarcoma group database

scientific article published on 09 March 2018

Preferences to receive unsolicited findings of germline genome sequencing in a large population of patients with cancer

scientific article published on 01 April 2020

Process validation and clinical evaluation of a protocol to generate gene-modified T lymphocytes for imunogene therapy for metastatic renal cell carcinoma: GMP-controlled transduction and expansion of patient's T lymphocytes using a carboxy anhydras

scientific article

Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor

scientific article published on 17 October 2016

Prognostic and predictive factors for outcome to first-line ifosfamide-containing chemotherapy for adult patients with advanced soft tissue sarcomas

article by Stefan Sleijfer et al published January 2010 in European Journal of Cancer

Prognostic factors for soft tissue sarcoma patients with lung metastases only who are receiving first-line chemotherapy: An exploratory, retrospective analysis of the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sa

scientific article published on 31 January 2018

Prognostic value and kinetics of circulating endothelial cells in patients with recurrent glioblastoma randomised to bevacizumab plus lomustine, bevacizumab single agent or lomustine single agent. A report from the Dutch Neuro-Oncology Group BELOB t

scientific article published on 4 June 2015

Prognostic value of circulating tumour cells for early recurrence after resection of colorectal liver metastases

scientific article published on 6 January 2015

Prospective Analysis in GIST Patients on the Role of Alpha-1 Acid Glycoprotein in Imatinib Exposure

scientific article published on 26 July 2016

Quantification of circulating endothelial cells by flow cytometry

scientific article published on 01 May 2009

RAS and BRAF mutations in cell-free DNA are predictive for outcome of cetuximab monotherapy in patients with tissue-tested RAS wild-type advanced colorectal cancer

scientific article published on 30 September 2019

Re: Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib

scientific article published on 23 August 2011

Real-world data on discordance between estrogen, progesterone, and HER2 receptor expression on diagnostic tumor biopsy versus tumor resection material.

scientific article published on 13 February 2019

Relevance of breast cancer antiestrogen resistance genes in human breast cancer progression and tamoxifen resistance

scientific article

Retronectin-assisted retroviral transduction of primary human T lymphocytes under good manufacturing practice conditions: tissue culture bag critically determines cell yield

scientific article

Retroviral vectors for clinical immunogene therapy are stable for up to 9 years

scientific article

Selective recruitment of breast cancer anti-estrogen resistance genes and relevance for breast cancer progression and tamoxifen therapy response

scientific article

Self-Seeding Microwells to Isolate and Assess the Viability of Single Circulating Tumor Cells ⬇️

scientific article published on 23 January 2019

Severe sarcopenia might be associated with a decline of physical independence in older patients undergoing chemotherapeutic treatment

scientific article published on 15 December 2017

Side effects of interferon-alpha therapy

scientific article

Somatic Tumor Mutations Detected by Targeted Next Generation Sequencing in Minute Amounts of Serum-Derived Cell-Free DNA.

scientific article published on 18 May 2017

Somatic mutation detection using various targeted detection assays in paired samples of circulating tumor DNA, primary tumor and metastases from patients undergoing resection of colorectal liver metastases

scientific article

Sunitinib-Induced Hypothyroidism Is due to Induction of Type 3 Deiodinase Activity and Thyroidal Capillary Regression ⬇️

scientific article published on August 3, 2011

Sunitinib-Induced Systemic Vasoconstriction in Swine Is Endothelin Mediated and Does Not Involve Nitric Oxide or Oxidative Stress

scientific article published on 28 November 2011

Surgery after treatment with imatinib and/or sunitinib in patients with metastasized gastrointestinal stromal tumors: is it worthwhile?

scientific article

Survival and Cost-Effectiveness of Trabectedin Compared to Ifosfamide Monotherapy in Advanced Soft Tissue Sarcoma Patients

scientific article published on 02 June 2019

T Cell Maturation Stage Prior to and During GMP Processing Informs on CAR T Cell Expansion in Patients

scientific article

T cell receptor (TCR) gene therapy to treat melanoma: lessons from clinical and preclinical studies

scientific article

T cell receptor-engineered T cells to treat solid tumors: T cell processing toward optimal T cell fitness

scientific article published on December 2014

TCR-Engineered T Cells Meet New Challenges to Treat Solid Tumors: Choice of Antigen, T Cell Fitness, and Sensitization of Tumor Milieu

scientific article published in 2013

TP53 Outperforms Other Androgen Receptor Biomarkers to Predict Abiraterone or Enzalutamide Outcome in Metastatic Castration-Resistant Prostate Cancer

scientific article published on 12 September 2018

Telatinib Is an Effective Targeted Therapy for Pseudomyogenic Hemangioendothelioma.

scientific article

Telomerase reverse transcriptase promoter mutations in tumors originating from the adrenal gland and extra-adrenal paraganglia

scientific article

Ten-Year Progression-Free and Overall Survival in Patients With Unresectable or Metastatic GI Stromal Tumors: Long-Term Analysis of the European Organisation for Research and Treatment of Cancer, Italian Sarcoma Group, and Australasian Gastrointesti

scientific article published on 31 March 2017

Thalidomide in solid tumours: the resurrection of an old drug

scientific article published in November 2004

The CYP2C19*2 genotype predicts tamoxifen treatment outcome in advanced breast cancer patients

scientific article published on 10 August 2011

The Future of Drug Development? Seeking Evidence of Activity of Novel Drugs in Small Groups of Patients ⬇️

scientific article published on April 29, 2013

The Prevalence and Prognostic Value of Low Muscle Mass in Cancer Patients: A Review of the Literature

scientific article published on 13 July 2016

The Prevalence of CD146 Expression in Breast Cancer Subtypes and Its Relation to Outcome

scientific article published on 5 May 2018

The Prognostic Role of β-Catenin Mutations in Desmoid-type Fibromatosis Undergoing Resection Only: A Meta-analysis of Individual Patient Data

scientific article published on 02 December 2019

The addition of pravastatin to chemotherapy in advanced gastric carcinoma: A randomised phase II trial ⬇️

scientific article published on August 18, 2010

The effect of baseline morphology and its change during treatment on the accuracy of Response Evaluation Criteria in Solid Tumours in assessment of liver metastases

scientific article published on 27 January 2014

The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies

scientific article published on 30 September 2019

The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact

scientific article published on 20 November 2019

The impact of age on outcome of embryonal and alveolar rhabdomyosarcoma patients. A multicenter study

scientific article published on October 1, 2012

The pharmacologic basis of ifosfamide use in adult patients with advanced soft tissue sarcomas

scientific article

The potential of statins as part of anti-cancer treatment

scientific article published on 11 January 2005

The role of mitochondrial DNA in breast tumors

scientific article published on 22 March 2019

The use of bevacizumab in colorectal, lung, breast, renal and ovarian cancer: where does it fit?

scientific article published on 11 September 2008

The use of circulating tumor cells in guiding treatment decisions for patients with metastatic castration-resistant prostate cancer

scientific article published on 12 April 2016

The vascular endothelial growth factor receptor inhibitor sunitinib causes a preeclampsia-like syndrome with activation of the endothelin system

scientific article published on 13 June 2011

Treatment of Metastatic Renal Cell Carcinoma With CAIX CAR-engineered T cells: Clinical Evaluation and Management of On-target Toxicity ⬇️

scientific article published on February 19, 2013

Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience

scientific article published on 01 May 2006

Tumor volume as an alternative response measurement for imatinib treated GIST patients

scientific article

Unsolicited findings of next-generation sequencing for tumor analysis within a Dutch consortium: clinical daily practice reconsidered

scientific article published on 13 April 2016

Using single-agent therapy in adult patients with advanced soft tissue sarcoma can still be considered standard care

scientific article published in November 2005

Validation of serum amyloid α as an independent biomarker for progression-free and overall survival in metastatic renal cell cancer patients.

scientific article published on 23 January 2012

Whole exome sequencing of cell-free DNA - A systematic review and Bayesian individual patient data meta-analysis

scientific article published on 13 December 2019

Wnt targets genes are not differentially expressed in desmoid tumors bearing different activating β-catenin mutations

scientific article published on 18 October 2018

[Drug research in oncology; advances in the genome era]

scientific article published in January 2014

mRNA and microRNA Expression Profiles in Circulating Tumor Cells and Primary Tumors of Metastatic Breast Cancer Patients ⬇️

scientific article published on April 19, 2011

mRNA expression profiles in circulating tumor cells of metastatic colorectal cancer patients.

scientific article published on 21 January 2015

mRNA levels of CD31, CD144, CD146 and von Willebrand factor do not serve as surrogate markers for circulating endothelial cells

scientific article

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