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List of works by Mouldy Sioud

A combined immunostimulatory and immunoinhibitory short interference RNA reduces hypercoagulability in a rat model of acute promyelocytic leukaemia

scientific article published on 10 June 2010

A facile method for interfering with off-target silencing mediated by the sense strand

scientific article published on January 2015

A novel peptide carrier for efficient targeting of antigens and nucleic acids to dendritic cells

scientific article

A nuclease-resistant protein kinase Cα ribozyme blocks glioma cell growth ⬇️

scientific article published on June 1, 1998

Advances in RNA sensing by the immune system: separation of siRNA unwanted effects from RNA interference.

scientific article published in January 2010

An experimental approach for systematic identification of antisense transcripts

scientific article published on 01 February 2004

An overview of the immune system and technical advances in tumor antigen discovery and validation

scientific article

Analysis of the NF-kappa B p65 subunit, Fas antigen, Fas ligand and Bcl-2-related proteins in the synovium of RA and polyarticular JRA

scientific article published on 01 March 1998

Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method

scientific article

Cancer cell-binding peptide fused Fc domain activates immune effector cells and blocks tumor growth

scientific article published on 04 October 2016

Cationic liposome-mediated delivery of siRNAs in adult mice

scientific article published in December 2003

Cell wall anchoring of the 37-kilodalton oncofetal antigen by Lactobacillus plantarum for mucosal cancer vaccine delivery

scientific article

Cerebrovascular accidents in Horton's disease. Apropos of a case

scientific article published on 01 May 1995

Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway.

scientific article published on February 2007

Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice.

scientific article

Combination of endostatin and a protein kinase Calpha DNA enzyme improves the survival of rats with malignant glioma

scientific article

Cytoplasmic delivery of siRNAs to monocytes and dendritic cells via electroporation

scientific article published in January 2015

DNA enzyme targeting TNF-α mRNA improves hemodynamic performance in rats with postinfarction heart failure ⬇️

scientific article published on November 1, 2001

Deciphering the code of innate immunity recognition of siRNAs

scientific article published on January 2009

Dendritic Cells Loaded with Tumor Antigens and a Dual Immunostimulatory and Anti-Interleukin 10-Specific Small Interference RNA Prime T Lymphocytes against Leukemic Cells.

scientific article published on December 2009

Design of bifunctional siRNAs: combining immunostimulation and gene-silencing in one single siRNA molecule

scientific article published on 20 November 2006

Development of TLR7/8 small RNA antagonists

scientific article published in January 2010

Development of a new high-affinity human antibody with antitumor activity against solid and blood malignancies

article

Discovery of differentially expressed genes: technical considerations

scientific article published on January 2007

Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine

scientific article published on 18 July 2016

Does the understanding of immune activation by RNA predict the design of safe siRNAs?

scientific article published on May 2008

Druggable signaling proteins

scientific article published on January 2007

Efficient siRNA targeted delivery into cancer cells by gastrin-releasing peptides

scientific article

Engineering better immunotherapies via RNA interference

scientific article

Engineering therapeutic cancer vaccines that activate antitumor immunity

scientific article published in January 2015

Epidermal growth factor receptor (EGFR) density may not be the only determinant for the efficacy of EGFR-targeted photoimmunotherapy in human head and neck cancer cell lines

scientific article published on 19 May 2018

Evidence for the involvement of FAM110C protein in cell spreading and migration

scientific article

Exosome-derived miRNAs and cellular miRNAs activate innate immunity.

scientific article published on 14 June 2013

Exploring 5'-Biotinylation of the Sense Strand to Improve siRNA Specificity and Potency

scientific article published on 01 January 2020

Expression profiling of microRNAs in cancer cells: technical considerations

scientific article published on 01 January 2008

Frizzled2 signaling regulates growth of high-risk neuroblastomas by interfering with β-catenin-dependent and β-catenin-independent signaling pathways

scientific article published on 15 June 2016

Galectin-1 and -3 gene silencing in immature and mature dendritic cells enhances T cell activation and interferon-γ production

scientific article published on 13 December 2011

Gene Expression Analysis in Blood Cells in Response to Unmodified and 2′-Modified siRNAs Reveals TLR-dependent and Independent Effects

article

Gene silencing by systemic delivery of synthetic siRNAs in adult mice

scientific article published on 01 April 2003

Gene silencing in mammalian cells by preformed small RNA duplexes

scientific article published on July 2002

Gene-array analysis of glioma cells after treatment with an anti-PKCalpha siRNA: a general protocol

scientific article published on January 2004

Generation of an effective anti-tumor immunity after immunization with xenogeneic antigens.

scientific article published in January 2003

Generation of new peptide-Fc fusion proteins that mediate antibody-dependent cellular cytotoxicity against different types of cancer cells

scientific article published on 4 November 2015

Harnessing the Antiviral-Type Responses Induced by Immunostimulatory siRNAs for Cancer Immunotherapy

scientific article published on 01 January 2020

High Cleavage Activity and Stability of Hammerhead Ribozymes with a Uniform 2′-Amino Pyrimidine Modification ⬇️

scientific article published on 01 September 1998

High-throughput analysis of microRNA gene expression using sensitive probes

scientific article published on 01 January 2005

Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts.

scientific article published on May 2008

How does autoimmunity cause tumor regression? A potential mechanism involving cross-reaction through epitope mimicry

scientific article

Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization

scientific article

Identification of genes differentially expressed in breast cancer cell line SKBR3: potential identification of new prognostic biomarkers

scientific article published on August 2004

Identification of novel carrier peptides for the specific delivery of therapeutics into cancer cells

scientific article published on 18 December 2002

Immunosuppressive factor blockade in dendritic cells via siRNAs results in objective clinical responses

scientific article published on 01 January 2015

Impaired expression of indoleamine 2, 3-dioxygenase in monocyte-derived dendritic cells in response to Toll-like receptor-7/8 ligands

scientific article published on 28 August 2007

Improving Dendritic Cell Cancer Vaccine Potency Using RNA Interference

scientific article published on 01 January 2020

Increased miR-21 expression during human monocyte differentiation into DCs

scientific article published on 01 June 2010

Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization

scientific article published on 22 March 2005

Influence of light fluence rate on the effects of photodynamic therapy in an orthotopic rat glioma model

scientific article published in January 2006

Inhibition of gene expression by nucleic acid enzymes in rodent models of human disease

scientific article published on 01 January 2004

Inhibition of stromal PlGF suppresses the growth of prostate cancer xenografts.

scientific article published on 3 September 2013

Innate sensing of self and non-self RNAs by Toll-like receptors

scientific article

Lamin A/C cleavage by caspase-6 activation is crucial for apoptotic induction by photodynamic therapy with hexaminolevulinate in human B-cell lymphoma cells

scientific article published on 31 July 2013

Main approaches to target discovery and validation

scientific article published on January 2007

Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins.

scientific article

Microbial sensing by hematopoietic stem and progenitor cells: Vigilance against infections and immune education of myeloid cells

scientific article published on 07 August 2020

Modified 2'-ribose small RNAs function as Toll-like receptor-7/8 antagonists

scientific article published on 01 January 2015

Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy

scientific article published in January 2015

Modulation of dendritic cell maturation and function by siRNA-bearing 5'-triphosphate

scientific article published on January 2010

Modulation of dendritic cell maturation and function with mono- and bifunctional small interfering RNAs targeting indoleamine 2,3-dioxygenase

scientific article published on 23 March 2009

Molecular basis for the immunostimulatory potency of small interfering RNAs

scientific article

Monitoring B cell response to immunoselected phage-displayed peptides by microarrays

scientific article

Mucosal vaccination with phage-displayed tumour antigens identified through proteomics-based strategy inhibits the growth and metastasis of 4T1 breast adenocarcinoma.

scientific article

NOD2/CARD15 on bone marrow CD34+ hematopoietic cells mediates induction of cytokines and cell differentiation

scientific article published on 24 February 2009

New Insights into Mesenchymal Stromal Cell‐Mediated T‐Cell Suppression Through Galectins ⬇️

scientific article published on February 1, 2011

Next Generation of Adoptive T Cell Therapy Using CRISPR/Cas9 Technology: Universal or Boosted?

scientific article published on 01 January 2020

On the delivery of small interfering RNAs into mammalian cells

scientific article

Optimized protocols for siRNA delivery into monocytes and dendritic cells

scientific article published in January 2010

Optimized siRNA Delivery into Primary Immune Cells Using Electroporation

scientific article published on 01 January 2020

Overcoming self-tolerance to tumour cells

scientific article published in January 2010

Overcoming the challenges of siRNA activation of innate immunity: design better therapeutic siRNAs

scientific article

Phage Display Libraries: From Binders to Targeted Drug Delivery and Human Therapeutics

scientific article published on 01 April 2019

Potential design rules and enzymatic synthesis of siRNAs

scientific article published on 01 January 2004

Profiling microRNA expression using sensitive cDNA probes and filter arrays

scientific article published on 01 October 2004

Profiling of miRNA expression and prediction of target genes

scientific article published in January 2010

Promises and challenges in developing RNAi as a research tool and therapy

scientific article published on January 2011

Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses

scientific article

Psychiatric disorders and endocrine diseases. Apropos of a 8 cases ⬇️

scientific article published on 01 December 1996

RNA and CRISPR Interferences: Past, Present, and Future Perspectives

scientific article published on 01 January 2020

RNA interference

scientific article published in January 2006

RNA interference and innate immunity

scientific article published on 16 March 2007

RNA interference below the immune radar

scientific article published on 01 May 2006

RNA interference: mechanisms, technical challenges, and therapeutic opportunities

scientific article

RNA therapeutics: function, design, and delivery. Preface

article published in 2010

Recent advances in hematopoietic stem cell transplantation and perspectives of RNAi applications

scientific article published on January 2010

Recent advances in small interfering RNA sensing by the immune system

scientific article published on 26 February 2010

Recombinant Lactobacillus plantarum induces immune responses to cancer testis antigen NY-ESO-1 and maturation of dendritic cells

scientific article

Releasing the Immune System Brakes Using siRNAs Enhances Cancer Immunotherapy

Ribozyme- and siRNA-mediated mRNA degradation: a general introduction

scientific article published on January 2004

Ribozymes, DNAzymes and small interfering RNAs as therapeutics

scientific article

Selection of peptides for specific delivery of oligonucleotides into cancer cells

scientific article published on January 2004

Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis

scientific article published on 06 February 2020

Selective killing of cancer cells by peptide-targeted delivery of an anti-microbial peptide

scientific article

Selective targeting of cancer cells using synthetic peptides

scientific article published on December 2003

Signaling through toll-like receptor 7/8 induces the differentiation of human bone marrow CD34+ progenitor cells along the myeloid lineage.

scientific article

Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients

scientific article published on 25 April 2013

Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: a central role for 2'-hydroxyl uridines in immune responses

scientific article published on 01 May 2006

Strategies for siRNA navigation to desired cells

scientific article

Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs

scientific article

Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma

scientific article published on March 2010

Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs.

scientific article published on 16 July 2007

Systematic identification of sense-antisense transcripts in mammalian cells

scientific article published on 14 December 2003

Systematic search for natural antisense transcripts in eukaryotes (review)

scientific article

Systemic delivery of synthetic siRNAs

scientific article

Systemic delivery of synthetic siRNAs

scientific article published on 01 January 2004

T cell cross-reactivity may explain the large variation in how patients respond to checkpoint inhibitors.

scientific article published on 30 January 2018

TLR agonists induce the differentiation of human bone marrow CD34+ progenitors into CD11c+ CD80/86+ DC capable of inducing a Th1-type response

scientific article published on 01 October 2007

Target validation using RNA interference in solid tumors.

scientific article published on January 2007

Targeted Killing of Monocytes/Macrophages and Myeloid Leukemia Cells with Pro-Apoptotic Peptides

scientific article published on 31 July 2019

Targeted delivery of antisense oligonucleotides and siRNAs into mammalian cells

scientific article

Targeting Raf-1 gene expression by a DNA enzyme inhibits juvenile myelomonocytic leukemia cell growth

scientific article published on 01 June 2002

Targeting stromal-cancer cell interactions with siRNAs.

scientific article published on January 2009

Therapeutic siRNAs

scientific article published on January 2004

Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs.

scientific article

Transcriptional targeting of small interfering RNAs into cancer cells

scientific article

Treatment options and individualized medicine

scientific article published on January 2007

Tyrosine kinase receptor-ras-ERK signal transduction pathway as therapeutic tarfet in cancer

scientific article

Unleashing the Therapeutic Potential of Dendritic and T Cell Therapies Using RNA Interference

scientific article published on 01 January 2020

Vector-based delivery of siRNAs: in vitro and in vivo challenges.

scientific article published on May 2008

What are the key targeted delivery technologies of siRNA now?

scientific article published in January 2010

siRNA delivery in vivo

scientific article published in January 2005

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