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List of works by Young-Ger Suh

15-Deoxy-Δ12,14-prostaglandin J2 activates PI3K-Akt signaling in human breast cancer cells through covalent modification of the tumor suppressor PTEN at cysteine 136.

scientific article published on 14 March 2018

15-Keto prostaglandin E2 suppresses STAT3 signaling and inhibits breast cancer cell growth and progression

scientific article published on 28 March 2019

2-Aminophenylpyrimidines as Novel Inhibitors of Aminoacyl-tRNA Synthetase Interacting Multifunctional Protein 2 (AIMP2)-DX2 for Lung Cancer Treatment

scientific article published on 01 April 2020

6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE).

scientific article published on 21 May 2015

A concise total synthesis of (+)-tetrabenazine and (+)-α-dihydrotetrabenazine

scientific article published on 16 March 2010

A critical element of the light-induced quaternary structural changes in YtvA-LOV.

scientific article published on 24 September 2015

A novel antitumor activity of deguelin targeting the insulin-like growth factor (IGF) receptor pathway via up-regulation of IGF-binding protein-3 expression in breast cancer

scientific article published on 21 January 2013

A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy

scientific article published on December 2008

A novel iNOS and COX-2 inhibitor from the aerial parts of Rodgersia podophylla

scientific article published on 19 June 2006

A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction

scientific article published on 22 May 2020

A stereo-controlled access to functionalized macrolactams via an aza-Claisen rearrangement

scientific article published on 22 November 2011

A synthetic cryptochrome inhibitor induces anti-proliferative effects and increases chemosensitivity in human breast cancer cells.

scientific article published on 22 September 2015

A versatile synthetic approach to grandisol monoterpene pheromone

scientific article

Activation and activators of TRPV1 and their pharmaceutical implication

scientific article

Allosteric regulation of pathologic angiogenesis: potential application for angiogenesis-related blindness

scientific article

An Electrophilic Deguelin Analogue Inhibits STAT3 Signaling in H-Ras-Transformed Human Mammary Epithelial Cells: The Cysteine 259 Residue as a Potential Target

scientific article published on 12 October 2020

An improved method of 18F peptide labeling: hydrazone formation with HYNIC-conjugated c(RGDyK)

scientific article published on 12 June 2006

Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists

scientific article published in September 2005

Asymmetric Synthesis of (-)-6-Desmethyl-Fluvirucinine A₁ via Conformationally-Controlled Diastereoselective Lactam-Ring Expansions

scientific article published on 14 September 2018

Asymmetric Total Synthesis of (+)-(3E)-Pinnatifidenyne via Abnormally Regioselective Pd(0)-Catalyzed Endocyclization.

scientific article published on 12 January 2018

Asymmetric Total Synthesis of (+)-Intricenyne via an Endocyclization Route to Oxocane Skeleton

scientific article published in December 2017

Asymmetric formal synthesis of schulzeines A and C

scientific article published on 13 June 2012

Asymmetric syntheses of 1-deoxy-6,8a-di-epi-castanospermine and 1-deoxy-6-epi-castanospermine

scientific article published on 25 May 2012

Asymmetric total synthesis of bacillariolide III, a marine oxylipin

scientific article published on 01 February 2004

Beta-lapachone inhibits pathological retinal neovascularization in oxygen-induced retinopathy via regulation of HIF-1α.

scientific article

Biarylcarboxybenzamide derivatives as potent vanilloid receptor (VR1) antagonistic ligands

scientific article published in February 2005

Cationic complex: (99m)Tc-N,N'-dimethyldiaminedithiol

scientific article published in August 2002

Chain-Branched acyclic phenethylthiocarbamates as vanilloid receptor antagonists ⬇️

scientific article published on May 5, 2003

Chain-branched 1,3-dibenzylthioureas as vanilloid receptor 1 antagonists

scientific article published in April 2004

Cholesterol-derived novel anti-apoptotic agents on the structural basis of ginsenoside Rk1 ⬇️

scientific article published on October 21, 2010

Co-Amorphous Screening for the Solubility Enhancement of Poorly Water-Soluble Mirabegron and Investigation of Their Intermolecular Interactions and Dissolution Behaviors

scientific article published on 05 September 2018

CoMFA and CoMSIA 3D QSAR studies on pimarane cyclooxygenase-2 (COX-2) inhibitors

scientific article published on May 2004

Collective Syntheses of Guaiane Sesquiterpenes: Stereoselective Syntheses of (+)-Dysodensiol F, (+)-10β,14-Dihydroxy-allo-aromadendrane, and (-)-Dendroside C Aglycon

scientific article published on 13 October 2020

Combined effect of vascular-leakage-blocker Sac-1004 and antiangiogenic drug sunitinib on tumor angiogenesis

scientific article

Comparison of pharmacokinetics of loxoprofen and its active metabolites after an intravenous, intramuscular, and oral administration of loxoprofen in rats: evidence for extrahepatic metabolism.

scientific article published in October 2005

Concise Syntheses of (+)-Macrosphelides A and B

scientific article published on 18 June 2005

Concise Synthesis of Catechin Metabolites 5-(3',4'-Dihydroxyphenyl)-γ-valerolactones (DHPV) in Optically Pure Form and Their Stereochemical Effects on Skin Wrinkle-Reducing Activities

scientific article published on 23 April 2020

Concise and Enantioselective Total Synthesis of 15-Deoxy-Δ12,14-Prostaglandin J2 ⬇️

scientific article published on November 5, 2010

Concise syntheses of (+)-macrosphelides A and B: studies on the macro-ring closure strategy

scientific article

Concise synthesis of Obovatol: Chemoselective ortho-bromination of phenol and survey of Cu-catalyzed diaryl ether couplings

scientific article

Concise synthesis of rodgersinol and determination of the C-10 absolute configuration

scientific article published on 01 January 2007

Conformationally-Inspired Total Syntheses of Ohmyungsamycins A and B and Structural Revision of Ohmyungsamycin B.

scientific article published on 30 January 2018

Construction of the Azacyclic Core of Tabernaemontanine-Related Alkaloids via Tandem Reformatsky-Aza-Claisen Rearrangement

scientific article

Conversion of Medium-Sized Lactams to α-Vinyl or α-Acetylenyl Azacycles via ,-Acetal TMS Ethers

Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity

scientific article published on 08 December 2015

Design and synthesis of a macrosphelide A-biotin chimera

scientific article published on 01 September 2014

Design, synthesis and biological evaluation of novel imidazopyridines as potential antidiabetic GSK3β inhibitors.

scientific article

Design, synthesis and identification of novel colchicine-derived immunosuppressant.

scientific article

Design, synthesis and insight into the structure-activity relationship of 1,3-disubstituted indazoles as novel HIF-1 inhibitors

scientific article published on September 2011

Design, synthesis, and biological evaluation of novel constrained meta-substituted phenyl propanoic acids as peroxisome proliferator-activated receptor alpha and gamma dual agonists

scientific article published on October 2008

Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis

scientific article published on 7 December 2012

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists.

scientific article published on 11 April 2009

Design, synthesis, and biological evaluation of phenylpropanamides as novel transient receptor potential vanilloid 1 antagonists

scientific article published on 26 September 2009

Design, synthesis, and structure-activity relationship of carbamate-tethered aryl propanoic acids as novel PPARalpha/gamma dual agonists.

scientific article published on 25 April 2007

Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry

scientific article published on 25 January 2020

Development of acetylated HDD kit for preparation of 188Re-HDD/lipiodol

scientific article published on 28 September 2006

Diastereoselective Total Synthesis of (-)-Galiellalactone

scientific article published on 13 November 2015

Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice

scientific article

Discovery of highly selective and potent monoamine oxidase B inhibitors: Contribution of additional phenyl rings introduced into 2-aryl-1,3,4-oxadiazin-5(6H)-one

scientific article published in March 2017

Discovery of novel indazole-linked triazoles as antifungal agents

scientific article

Discovery of small molecules that enhance astrocyte differentiation in rat fetal neural stem cells

scientific article published on 29 September 2011

Divergent synthetic route to new cyclopenta[c]pyran iridoids: syntheses of jatamanin A, F, G and J, gastrolactone and nepetalactone

scientific article published on 08 December 2015

Efficient and Divergent Enantioselective Syntheses of DHPVs and Anti-Inflammatory Effect on IEC-6 Cells

scientific article published on 08 May 2020

Enantioselective total synthesis of a natural iridoid

scientific article published on 27 May 2011

Expedient synthesis of chiral homoallylamines via N,O-acetal TMS ethers and its application

scientific article

Fine tuning of 4,6-bisphenyl-2-(3-alkoxyanilino)pyrimidine focusing on the activity-sensitive aminoalkoxy moiety for a therapeutically useful inhibitor of receptor for advanced glycation end products (RAGE)

scientific article

First total syntheses of (-)-macrosphelides J and K and elucidation of their absolute configuration

scientific article published on 15 January 2009

First total synthesis and structural confirmation of fluvirucinine A2 via an iterative ring expansion strategy

scientific article published on 01 May 2010

Functional divergency oriented synthesis of azoninones as the key intermediates for bioactive indolizidine alkaloids analogs.

scientific article

Glucal-conjugated sterols as novel vascular leakage blocker: structure-activity relationship focusing on the C17-side chain.

scientific article published on 25 January 2014

Hepatoprotective pyrrole derivatives of Lycium chinense fruits

scientific article published in January 2003

Heterocycle-linked phenylbenzyl amides as novel TRPV1 antagonists and their TRPV1 binding modes: constraint-induced enhancement of in vitro and in vivo activities.

scientific article

High affinity antagonists of the vanilloid receptor

scientific article

Hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retina is suppressed by HIF-1α destabilization by SH-1242 and SH-1280, novel hsp90 inhibitors

scientific article

Identification and Semi-Synthesis of 3-O-Protocatechuoylceanothic Acid, a Novel and Natural GPR120 Agonist †

scientific article published on 26 September 2019

Identification and Structural Analysis of New Nrf2 Activators by Mechanism-Based Chemical Transformation of 15-Deoxy-Δ12, 14 -PGJ2.

scientific article published on 25 July 2016

Identification and validation of cryptochrome inhibitors that modulate the molecular circadian clock

scientific article

Identification of a novel circadian clock modulator controlling BMAL1 expression through a ROR/REV-ERB-response element-dependent mechanism.

scientific article published on 12 December 2015

Identification of galiellalactone-based novel STAT3-selective inhibitors with cytotoxic activities against triple-negative breast cancer cell lines

scientific article published on 23 June 2017

Identification of small molecule inhibitors of the STAT3 signaling pathway: Insights into their structural features and mode of action.

scientific article published on 26 July 2015

Identification, biological activity, and mechanism of the anti-ischemic quinolone analog

scientific article published on 26 July 2007

Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents

scientific article published on 20 February 2019

Kinetics of the Solution-Mediated Polymorphic Transformation of the Novel l-Carnitine Orotate Polymorph, Form-II

scientific article published on 01 October 2018

Ligand-based design, synthesis, and biological evaluation of 2-aminopyrimidines, a novel series of receptor for advanced glycation end products (RAGE) inhibitors

scientific article

Light-regulated tetracycline binding to the Tet repressor

scientific article published on 29 January 2014

Lipiodol solution of 188Re-HDD as a new therapeutic agent for transhepatic arterial embolization in liver cancer: preclinical study in a rabbit liver cancer model

scientific article published on December 2003

Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells

scientific article published on 25 July 2011

N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor

scientific article

N-4-Substituted-benzyl-N'-tert-butylbenzyl thioureas as vanilloid receptor ligands: investigation on the role of methanesulfonamido group in antagonistic activity

scientific article published in February 2004

N-4-methansulfonamidobenzyl-N'-2-substituted-4-tert-butyl-benzyl thioureas as potent vanilloid receptor antagonistic ligands

scientific article published in April 2004

Nicrophorusamides A and B, Antibacterial Chlorinated Cyclic Peptides from a Gut Bacterium of the Carrion Beetle Nicrophorus concolor.

scientific article published on 7 November 2017

Novel C6-substituted 1,3,4-oxadiazinones as potential anti-cancer agents

scientific article published on 23 October 2015

Novel Galiellalactone Analogues Can Target STAT3 Phosphorylation and Cause Apoptosis in Triple-Negative Breast Cancer.

scientific article

Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy

scientific article published on 09 October 2018

Novel human umbilical vein endothelial cells (HUVEC)-apoptosis inhibitory phytosterol analogues: insight into their structure-activity relationships

scientific article published on 01 March 2012

Novel non-vanilloid VR1 antagonist of high analgesic effects and its structural requirement for VR1 antagonistic effects

scientific article

Novel potent antagonists of transient receptor potential channel, vanilloid subfamily member 1: structure-activity relationship of 1,3-diarylalkyl thioureas possessing new vanilloid equivalents

scientific article

Part II. Development of novel colchicine-derived immunosuppressants with improved pharmacokinetic properties

scientific article published on 25 August 2012

Potent inhibition of in vivo angiogenesis and tumor growth by a novel cyclooxygenase-2 inhibitor, enoic acanthoic acid.

scientific article published on 19 September 2007

Practical and Sustainable Synthesis of Optically Pure Levocabastine, a H₁ Receptor Antagonist

scientific article published on 15 November 2017

Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products (RAGE)

scientific article (publication date: 22 May 2014)

Rapid and Efficient Separation of Decursin and Decursinol Angelate from Angelica gigas Nakai using Ionic Liquid, (BMIm)BF4, Combined with Crystallization

scientific article published on 28 June 2019

Ring-truncated deguelin derivatives as potent Hypoxia Inducible Factor-1α (HIF-1α) inhibitors

scientific article published on 30 September 2015

Role of heme oxygenase-1 in potentiation of phagocytic activity of macrophages by taurine chloramine: Implications for the resolution of zymosan A-induced murine peritonitis

scientific article published on 09 February 2018

Sac-0601 prevents retinal vascular leakage in a mouse model of diabetic retinopathy.

scientific article published on 4 February 2011

Sac-1004, a Pseudo-Sugar Derivative of Cholesterol, Restores Erectile Function through Reconstruction of Nonleaky and Functional Cavernous Angiogenesis in the Streptozotocin Induced Diabetic Mouse

scientific article

Sac-1004, a novel vascular leakage blocker, enhances endothelial barrier through the cAMP/Rac/cortactin pathway.

scientific article published on 9 May 2013

Sac-1004, a vascular leakage blocker, reduces cerebral ischemia-reperfusion injury by suppressing blood-brain barrier disruption and inflammation

scientific article

Silicon switch approach in TRPV1 antagonist MK-056 and its analogues

scientific article published on 10 November 2009

Simultaneous quantitative monitoring of drug-induced caspase cascade pathways in carcinoma cells

scientific article

Stereoselective Synthesis of 1,4,5-Tri-cis-guaiane Sesquiterpene: First Total Synthesis of (-)-Dendroside C Aglycon.

scientific article published on 16 January 2018

Stereoselective formation of N-acyliminium ion via chiral N,O-acetal TMS ether and its application to the synthesis of beta-amino acids

scientific article published on 01 October 2003

Stereoselective synthesis of 7-epi-incarvilline

scientific article published on 23 January 2013

Structural basis for depletion of heat shock protein 90 client proteins by deguelin.

scientific article

Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem Cells.

scientific article published on 16 May 2019

Structure-activity relationship of pentacylic triterpene esters from Uncaria rhynchophylla as inhibitors of phospholipase Cgamma1.

scientific article published on 24 September 2008

Structure-activity relationship of the 7-hydroxy benzimidazole analogs as glycogen synthase kinase 3β inhibitor

scientific article published on 28 January 2012

Syntheses and anti-MRSA activities of the C3 analogs of mansonone F, a potent anti-bacterial sesquiterpenoid: insights into its structural requirements for anti-MRSA activity

scientific article published in September 2004

Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization

scientific article published on 16 June 2015

Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90.

scientific article published on 14 May 2015

Synthesis and Structure-Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy

scientific article published on 21 April 2020

Synthesis and anti-inflammatory effects of novel pimarane diterpenoid analogs

scientific article published on July 2004

Synthesis and biological evaluation of C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors

scientific article published on 30 September 2016

Synthesis and structural optimization of multiple H-bonding region of diarylalkyl (thio)amides as novel TRPV1 antagonists.

scientific article

Synthesis of C4-modified acanthoic acid analogs and their biological evaluation as nitric oxide inhibitors

scientific article

Synthesis of N,N',N"-trisubstituted thiourea derivatives and their antagonist effect on the vanilloid receptor

scientific article published in February 2003

Synthetic studies on bioactive natural polyketides: intramolecular nitrile oxide-olefin cycloaddition approach for construction of a macrolactone skeleton of macrosphelide B

scientific article published on 10 June 2011

Taurine Chloramine Stimulates Efferocytosis Through Upregulation of Nrf2-Mediated Heme Oxygenase-1 Expression in Murine Macrophages: Possible Involvement of Carbon Monoxide

scientific article published in July 2015

Taurine chloramine potentiates phagocytic activity of peritoneal macrophages through up-regulation of dectin-1 mediated by heme oxygenase-1-derived carbon monoxide

scientific article published on 15 December 2017

The cryptochrome inhibitor KS15 enhances E-box-mediated transcription by disrupting the feedback action of a circadian transcription-repressor complex.

scientific article published on 10 March 2018

The structure-activity relationships of mansonone F, a potent anti-MRSA sesquiterpenoid quinone: SAR studies on the C6 and C9 analogs

scientific article published on 19 October 2005

The versatile conversion of acyclic amides to alpha-alkylated amines

scientific article published on 01 May 2002

Total Synthesis of Anmindenol A and Its Application to the Design, Synthesis, and Biological Evaluation of Derivatives Thereof

scientific article published on 12 August 2019

Total synthesis of (+)-Brefeldin A.

scientific article published in June 2002

Total synthesis of (+)-brasilenyne via concise construction of an oxonane framework containing a 1,3-cis,cis-diene

scientific article published on 01 January 2018

Total synthesis of (-)-deguelin via an iterative pyran-ring formation strategy.

scientific article published in May 2015

WS9326H, an Antiangiogenic Pyrazolone-Bearing Peptide from an Intertidal Mudflat Actinomycete.

scientific article published on 20 March 2018

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