List of works - Feng Gu

A 'new lease of life': FnCpf1 possesses DNA cleavage activity for genome editing in human cells.

scientific article

A Single Multiplex crRNA Array for FnCpf1-Mediated Human Genome Editing

scientific article published on 15 June 2018

Basic and Clinical Application of Adeno-Associated Virus-Mediated Genome Editing

scientific article published on 28 February 2019

CRISPR/Cas9-AAV Mediated Knock-in at NRL Locus in Human Embryonic Stem Cells.

scientific article

CRISPR/Cas9-loxP-Mediated Gene Editing as a Novel Site-Specific Genetic Manipulation Tool

scientific article

Comparison of non-canonical PAMs for CRISPR/Cas9-mediated DNA cleavage in human cells

scientific article

Deciphering relationship between microhomology and in-frame mutation occurrence in human CRISPR-based gene knockout

scientific article published on 14 June 2016

DeepCRISPR: optimized CRISPR guide RNA design by deep learning.

scientific article published on 26 June 2018

Efficient Human Genome Editing Using SaCas9 Ribonucleoprotein Complexes

scientific article published on 17 May 2019

Efficient cleavage resolves PAM preferences of CRISPR-Cas in human cells

scientific article published on 28 October 2019

Functional non-homologous end joining patterns triggered by CRISPR/Cas9 in human cells

scientific article published on 08 May 2018

High-fidelity SaCas9 identified by directional screening in human cells

scientific article published on 09 July 2020

Identification of RPGR ORF15 mutation for X-linked retinitis pigmentosa in a large Chinese family and in vitro correction with prime editor

scientific article published in 2022

Molecular diagnosis of putative Stargardt disease by capture next generation sequencing

scientific article (publication date: 2014)

Photoreceptor Cell-Derived CAPN5 Regulates Retinal Pigment Epithelium Cell Proliferation Through Direct Regulation of SLIT2 Cleavage.

scientific article published in April 2018

Questions about NgAgo.

scientific article published on 15 November 2016

Recapitulating X-Linked Juvenile Retinoschisis in Mouse Model by Knock-In Patient-Specific Novel Mutation.

scientific article

Recapitulating and Correcting Marfan Syndrome in a Cellular Model

scientific article

SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells

scientific article published on 16 December 2017

List of works by Feng Gu

A 'new lease of life': FnCpf1 possesses DNA cleavage activity for genome editing in human cells.

A Single Multiplex crRNA Array for FnCpf1-Mediated Human Genome Editing

Basic and Clinical Application of Adeno-Associated Virus-Mediated Genome Editing

CRISPR/Cas9-AAV Mediated Knock-in at NRL Locus in Human Embryonic Stem Cells.

CRISPR/Cas9-loxP-Mediated Gene Editing as a Novel Site-Specific Genetic Manipulation Tool

Comparison of non-canonical PAMs for CRISPR/Cas9-mediated DNA cleavage in human cells

Deciphering relationship between microhomology and in-frame mutation occurrence in human CRISPR-based gene knockout

DeepCRISPR: optimized CRISPR guide RNA design by deep learning.

Efficient Human Genome Editing Using SaCas9 Ribonucleoprotein Complexes

Efficient cleavage resolves PAM preferences of CRISPR-Cas in human cells

Functional non-homologous end joining patterns triggered by CRISPR/Cas9 in human cells

High-fidelity SaCas9 identified by directional screening in human cells

Identification of RPGR ORF15 mutation for X-linked retinitis pigmentosa in a large Chinese family and in vitro correction with prime editor

Molecular diagnosis of putative Stargardt disease by capture next generation sequencing

Photoreceptor Cell-Derived CAPN5 Regulates Retinal Pigment Epithelium Cell Proliferation Through Direct Regulation of SLIT2 Cleavage.

Questions about NgAgo.

Recapitulating X-Linked Juvenile Retinoschisis in Mouse Model by Knock-In Patient-Specific Novel Mutation.

Recapitulating and Correcting Marfan Syndrome in a Cellular Model

SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells